Abstract: Path planning method for computing optimal parking maneuvers for road vehicles including the steps of computing a set of value functions of a cost function of parking maneuvers reaching the target set of states as unique viscosity solution of a Hamilton Jacobi Bellman equation, supplying the set of value functions, together with a starting state of the vehicle, as input to the dynamic programming calculation procedure calculating at least the set of vehicle controls. The set of equations modeling the evolution of the state of said road vehicle is a switched system of equations between a first sub-system if the vehicle is in forward motion and a second sub-system if the vehicle is in reverse motion. The cost function takes into account the arrival time a number of direction changes of the road vehicle between forward motion and reverse motion.

Abstract: A device for enhancing a user's grasping capability comprises a belt-like support configured to be tightly fitted about a user's part of the body; an articulated gripping element having a plurality of phalanxes: proximal, fixed to the support, intermediate and distal, which are articulated to each other by articular joints; a motor unit fixed to the support; a winding drum; a tendon partially wound on the drum and extending along the phalanxes and the joints, arranged so that, by pulling it from the drum, the phalanxes rotate about respective articular joints and move the articulated gripping element from an extended position to a gripping bow-shaped position, causing a flexion/extension movement of the articulated gripping element, the joints configured so that by releasing the tendon from the drum, the phalanxes rotate about the respective joints and move the articulated gripping element between gripping bow-shaped position and extended position.

Abstract: The present invention relates to new synthetic molecules with agonist activity of human Toll-like Receptor 4 (TLR4), compositions comprising them and uses thereof for the treatment of diseases in which it is useful to induce or increase an immune response. The compounds have general formula (1), wherein R1 is a saturated C8-C16 aliphatic chain having a =0 on C1, said chain being free from —OH substituents on C3, wherein R2 is a saturated C8-C16 aliphatic chain having a ?O on C1, said chain being free from —OH substituents on C3, wherein R3 is a saturated C8-C16 aliphatic chain having a ?O on C1, said chain being free from —OH substituents on C3; wherein R4 is a hydrogen atom (H) or a phosphate group (PO42?).

Abstract: The present invention relates to magnetic nanoparticles based on iron oxide having cubic shape, suitably functionalized for the release of targeting chemotherapeutic agents, i.e. selectively in the tumors being treated The invention also relates to the pharmaceutical compositions having such nanoparticles and to their use in combined oncological therapies of hyperthermia and chemotherapy, useful in particular in the treatment of ovarian tumors.

Abstract: Method and relative system for the measurement of haemodynamic indices, said method comprising: acquiring an ultrasound image of at least one segment of an arterial vessel; identifying in said image at least one sample volume; obtaining a time series indicating the blood velocity, or velocity signal (9), in said sample volume and in at least one cardiac cycle; calculating, by means of a processor, a first area (4) equal to the area subtended by the velocity signal (9) between the sample (6) relating to the instant of systole start of said at least one cardiac cycle and the sample (7) of systolic peak; calculating, by means of a processor, a second area (5) subtended by the velocity signal (9) between the sample (7) of systolic peak and the sample (8) relating to the instant of end diastole of said at least one cardiac cycle; calculating the relationship between the second area (5) and the first area (4); selecting a time instant of interest in said at least one cardiac cycle; obtaining the spatial distributio

Abstract: The present invention refers to a process for the preparation of a graphene dispersion comprising the following steps: i) providing cellulose acetate flakes or powders; ii) swelling the cellulose acetate flakes or powders in an alcohol having from 1 to 3 carbon atoms; iii) adding acetic anhydride in a concentration range from 30 to 50 wt % referred to the total weight of the mixture; iv) adding graphene nanoplatelets to yield a graphene dispersion. The graphene dispersion is used as ink for composite materials that are employed in the field of foldable electronics. The invention relates also to a composite material comprising uniformly dispersed graphene nanoplatelets and its use for manufacturing electronic devices.

Abstract: The present invention relates to a compound of formula (1): or an analogue thereof or a pharmaceutically acceptable salt thereof, for use in the treatment of a brain tumor, wherein the compound is administered intranasally and relative pharmaceutical compositions.

Abstract: A drying device for processing a gas to be dried, in particular air, comprises an air/air exchanger which includes an inlet for the gas to be dried and an outlet for the dried gas, an evaporator which receives the gas to be dried from the air/air exchanger, the evaporator being formed by means of a plurality of adjacent layers. The layers comprise at least a first layer configured for the passage of a refrigerating fluid, at least a second layer configured to receive the gas to be dried from the air/air exchanger and a plurality of third layers configured to receive a phase change material. The layers are arranged in a sequence which comprises in alternation a first layer, a third layer, a second layer and a further third layer.

Abstract: The present invention concerns 4-amino-2-pyrido-bicyclic pyrimidines of Formula (I) that function as type II topoisomerase inhibitors and their use thereof as medicaments especially in the treatment of cancer. The invention also provides a method for the manufacture of 4-amino-2-pyrido bicyclic pyrimidines of Formula (I).

Abstract: A process and device for the plenoptic capture of photographic or cinematographic images are described, both based on the correlation measure or “Correlation Plenoptic Imaging” (CPI), comprising the steps of splitting a primary light beam (6) coming from at least one light source in at least two distinct light beams (7, 8), directing said distinct light beams towards two image capturing sensors to capture images, so that the first light beam is directed towards at least one first capturing sensor to capture a spatial measure of a scene and the second light beam is directed towards a second capturing sensor to capture an angular measure of said scene, said angular measure being adapted to provide the propagation direction of the light beam coming from the scene, said spatial measure being adapted to provide the conventional two-dimensional capture of the image of the scene.

Abstract: A process for manufacturing customized facemasks, includes: producing respective impressions of patient's forehead and chin, to record an anatomic structure thereof, using impression materials commonly utilized in dentistry for intraoral impressions; producing respective 3D digital images of a patient's forehead and chin through a 3d-scanning of the forehead and chin impressions; 3D printing of customized forehead and chin pads; detecting patient's side profile line from a side picture of patient's face; 3D printing of a midline rod modelled according to said profile line; and assembling the forehead and chin pads and said midline rod into a facemask featuring a facial frame providing retention to elastic bands connectable to an intraoral appliance, in the forehead pad a temperature sensor is inserted while a pressure sensor is embedded into the chin pad.

Abstract: Methods are disclosed for the use of GC-1 (sobetirome), a prodrug thereof, or a pharmaceutically acceptable salt or prodrug thereof to increase liver regeneration and healing in liver transplant donors and recipients.

Abstract: A nucleic acid molecule encoding a chimeric chondroitin sulfate proteoglycan 4 (CSPG4) protein, wherein the chimeric CSPG4 protein comprises, from the N-terminal to the C-terminal: i) a first portion derived from the human CSPG4 sequence and a second portion derived from the canine CSPG4 sequence or ii) a first portion derived from the canine CSPG4 sequence and a second portion derived from the human CSPG4 sequence.

Abstract: A comprehensive system for treatment of wrist joint proprioception. The system includes a manipulandum unit and a controller. The unit includes a base, a handle, a linkage assembly, and motors. The base supports a subject's forearm, and the handle is gripped by the palm. The linkage assembly connects the handle to the base, and establishes three DOFs. The motors are operatively connected to the linkage assembly. The controller is programmed to actuate, and receive feedback information from, each of the plurality of motors. Further, the controller is programmed to perform wrist proprioception assessment operations by actuating the plurality of motors to effectuate movement of the handle relative to the base in a prescribed manner indicative of position motion sense acuity as an objective measure of wrist proprioception functioning. The controller is optionally further programmed to perform rehabilitation training via controlled operation of the unit and a virtually reality environment.

Abstract: Process for the plasma surface treatment under vacuum of a fabric, nonwoven fabric or paper material for obtaining materials to be used for the filtration and separation of two immiscible liquids.

Abstract: A device for cutting a web of material comprises movement means for moving a web of material to be cut, defining a feed path for the web at least partly rotatable about a central axis and equipped with at least one conveyor mounted around the central axis, at least one cutting head equipped with a laser source and an optical system configured to direct the laser beam towards a cutting zone, where the optical system of the cutting head comprises at least one directing member located inside the conveyor to direct the laser beam away from the central axis towards the cutting zone.

Abstract: A new grape variety distinguished by its strong blistering of the upper side of the leaf blade, cuneiform shaped leaves, fruit cluster of medium bunch density with 3-4 wings, medium harvesting time (early September in northeastern Italy), and resistance to downy mildew and powdery mildew.

Abstract: A new grape variety distinguished by its resistance to downy mildew and powdery mildew, strong blistering on the upper side of the leaf blade, early-medium harvesting time (end of August in northeastern Italy), and semi-erect shoot attitude.

Abstract: A new grape variety distinguished by its high vigour, circular shaped leaves, medium weight fruit clusters, early-medium harvesting time (end of August in northeastern Italy), green dorsal and ventral internodes, and resistance to downy mildew and powdery mildew.

Abstract: A new grape variety distinguished by its high vigour with a semi-erect growth habit, low-medium blistering of the upper side of the leaf blade, circular shaped leaves, fruit clusters of medium or medium-large bunch density with 3-4 wings, medium harvesting time (early September in northeastern Italy), and resistance to downy mildew.