Patents Assigned to Universite Claude Bernard Lyon
  • Publication number: 20220186321
    Abstract: A method of prognosis of patient outcome and of the resistance to a chemotherapy treatment of an individual afflicted by a tumor. The method involves determining the amount of the product of each of at least 21 genes belonging to the group of 160 genes as set forth in SEQ ID NO: 1 to SEQ ID NO: 160.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 16, 2022
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE LÉON BERARD, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, UNIVERSITÉ CLAUDE BERNARD LYON 1
    Inventors: Véronique MAGUER-SATTA, Boris GUYOT, Flora CLÉMENT, Pierre SAINTIGNY, Jean-Philippe FOY, Emmanuel DELAY
  • Publication number: 20220178949
    Abstract: The invention relates to a process in vitro for diagnosing a paraneoplastic neurological syndrome (PNS) associated with a tumor in an individual, comprising the detection of at least one antibody chosen among antibodies against TRIM9 and antibodies against TRIM67, in a biological fluid of said individual.
    Type: Application
    Filed: May 2, 2019
    Publication date: June 9, 2022
    Applicants: HOSPICES CIVILS DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Le Duy DO, Jérôme HONNORAT, Véronique ROGEMOND
  • Patent number: 11351180
    Abstract: The present invention relates to a pharmaceutical or veterinary composition for the use thereof in preventing and/or treating infection by the influenza viruses. Said composition is characterized in that it contains, in an appropriate pharmaceutical carrier, at least one compound selected from among Etilefrine and Diltiazem.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: June 7, 2022
    Assignees: UNIVERSITE CLAUDE BERNARD LYON 1, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), HOSPICES CIVILS DE LYON, UNIVERSITE LAVAL
    Inventors: Manuel Rosa-Calatrava, Olivier Terrier, Julien Textoris, Guy Boivin, Mario Pizzorno
  • Publication number: 20220146402
    Abstract: A particle detector includes at least one resonant cavity partially formed at least by a first reflector, a second reflector disposed at a distance from the first reflector and a channel located between the first and second reflectors, the channel being intended to receive at least one fluid comprising particles and to receive at least one light radiation; and at least one detection system having at least one photodetector. The particle detector is configured so that a portion of the light radiation present in the channel escapes from the cavity throughout the second reflector and reaches the detection system, thereby enabling the at least one photodetector to detect leakage of the cavity. The second reflector is a photonic crystal membranes PCM based reflector.
    Type: Application
    Filed: December 23, 2019
    Publication date: May 12, 2022
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CPE LYON, ECOLE CENTRALE DE LYON, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1
    Inventors: Gabriel JOBERT, Salim BOUTAMI, Maryse FOURNIER, Christian SEASSAL
  • Patent number: 11313800
    Abstract: A method for the detection and quantification, in a complex aqueous fluid, of additives and water-soluble polymers used in the enhanced recovery of oil and shale gas.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: April 26, 2022
    Assignees: TOTAL SA, UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Mattéo Martini, Olivier Tillement, Arthur Marais, Christian Hurtevent, Stéphane Jouenne
  • Publication number: 20220119893
    Abstract: The invention relates to an in vitro process for classifying a glioma, comprising the following steps: a. Measuring at least, from a glioma patient biological sample, the Alternative Lengthening of Telomeres (ALT) status of said glioma; b. Optionally, determining the isocitrate dehydrogenase genes mutation status (IDH status) of said glioma; c. Based on the data obtained in steps (a) and optionally (b) and, if available, on the histological grade of said glioma, classifying said glioma in one of the five following classes: oligodendroglioma-like, glioblastoma IDHwt-like, glioblastoma IDHmt-like, low-grade astrocytoma-like, and other gliomas.
    Type: Application
    Filed: February 19, 2020
    Publication date: April 21, 2022
    Applicants: HOSPICES CIVILS DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1
    Inventor: Delphine PONCET
  • Patent number: 11287397
    Abstract: This gaseous elementary-particle detector is equipped with a readout plate comprising: conductive tiles (80) that are all identical to one another and all located at the same distance from an exterior face (39), these conductive tiles being distributed over the front face of a dielectric layer (72) and being mechanically separated from one another by a dielectric material (76), the smallest dimension of each tile being larger than 300 ?m, and electrical connections (88), which are located under the dielectric layer (72) and which electrically connect the conductive tiles in series so as to form conductive strips, these electrical connections being arranged so that each conductive tile belongs to a single conductive strip and each side of one tile is adjacent to the side of another tile belonging to another conductive strip.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: March 29, 2022
    Assignees: Université Claude Bernard Lyon 1, Centre National De La Recherche Scientifique
    Inventor: Imad Laktineh
  • Patent number: 11286557
    Abstract: A method of preparing a crystalline thin film having a formula MY2 includes (1) preparing an MYx amorphous film by atomic layer deposition on a surface of a substrate, and (2) annealing the amorphous MYx film at 350° C. or more to provide the crystalline MY2 film. The amorphous MYx film is formed from at least one metal M precursor and at least one element Y precursor, wherein x is 1.5 to 3.1, M is tungsten or molybdenum, and Y is sulfur or selenium. Step (1) includes a) introducing a first metal M precursor or element Y precursor into a deposition chamber, b) purging with inert gas, c) introducing a second metal M precursor when the first precursor is element Y, or element Y precursor when the first precursor is metal M, d) purging with inert gas, e) repeating steps a) to d), and f) obtaining the amorphous MYx film.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: March 29, 2022
    Assignees: Commissariat A L'Energie Atomique Et Aux Engergies Alternatives, Centre National De La Recherche Scientifique, Universite Claude Bernard Lyon 1, CPE Lyon Formation Continue et Recherche
    Inventors: Stéphane Cadot, Francois Martin, Elsje Quadrelli, Chloé Thieuleux
  • Publication number: 20220089966
    Abstract: The present invention relates to a dinuclear molybdenum complex with ligands selected from fatty tertiary amines of formula (I): R—N[(CH2)nR2][(CH2)nR3]??(I) wherein R represents a linear or branched alkyl comprising 3 to 30 carbon atoms, preferably 3 to 20, advantageously 7 to 17 carbon atoms; n, identical or different, represents 2 or 3; R2 and R3, identical or different, represent an O, OR, NR?2, COOR?, or COO group, where R?, identical or different, represents a hydrogen atom or an alkaline or alkaline earth metal, preferably R? is H, preferably R2 and R3, identical or different, represent an OH or NH2 group.
    Type: Application
    Filed: January 21, 2020
    Publication date: March 24, 2022
    Applicants: TOTAL MARKETING SERVICES, Centre national de la recherche scientifique, ECOLE CENTRALE DE LYON, Université Claude Bernard Lyon 1
    Inventors: Benoît THIEBAUT, Catherine CHARRIN, Camella OUMAHI, Maria Isabel DE BARROS BOUCHET, Pavel AFANASIEV
  • Publication number: 20220091018
    Abstract: An optical particle detector including at least one channel intended to receive a fluid carrying at least one particle, and across which light rays are intended to pass such that the light rays are partially scattered by the at least one particle, a plurality of photodetectors capable of receiving said scattered light rays, wherein the detector includes at least one optical waveguide configured to collect, at least at one entrance of the waveguide, light rays that were not scattered by the at least one particle and having crossed the channel, and to reinject the unscattered light rays into the channel through at least one exit of the waveguide.
    Type: Application
    Filed: September 21, 2021
    Publication date: March 24, 2022
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CPE LYON FORMATION CONTINUE ET RECHERCHE, ECOLE CENTRALE DE LYON, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1
    Inventors: Salim BOUTAMI, Maryse FOURNIER, Gabriel JOBERT, Christian SEASSAL, Cécile JAMOIS
  • Patent number: 11267947
    Abstract: A method for modifying a cellular polymer foam with apparent porosity, which includes providing a cellular polymer foam with apparent porosity, placing the cellular polymer foam in contact with at least one compound in order to obtain a cellular polymer foam including on the surface thereof an intermediate phase formed from the compound having at least one catechol unit. The foam may be used as a catalyst substrate.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: March 8, 2022
    Assignees: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1
    Inventors: David Edouard, Vincent Ritleng, Loïc Jierry, Nguyet Trang Thanh Chau Dalencon
  • Publication number: 20220028574
    Abstract: The invention relates to an electrically insulating composite material (1) comprising a polyepoxide matrix (2) of cycloaliphatic type or of diglycidyl ether type in a content of less than 40% by mass, from 20 to 75% by mass of one or several micrometric and/or mesometric filler(s) (3), and from 0.1 to 20% by mass of at least one ionic liquid (4), the masses being expressed relative to the total mass of the electrically insulating composite material (1). The invention also relates to a method for manufacturing such an electrically insulating composite material (1), as well as its use for an electrically insulating support (9) in a metal-enclosed substation (5).
    Type: Application
    Filed: December 27, 2019
    Publication date: January 27, 2022
    Applicants: SUPERGRID INSTITUTE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE CLAUDE BERNARD LYON 1, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVERSITE JEAN MONNET SAINT ETIENNE
    Inventors: Thibaut LEFORT, Damien BACHELLERIE, Sébastien PRUVOST, Jannick DUCHET, Sébastien LIVI
  • Patent number: 11229597
    Abstract: The present invention relates to a novel pharmaceutical composition comprising doxycycline for topical application, in particular to the eye and eyelids. The invention also relates to this topical composition for use in the treatment of bacterial infections of the skin and mucous membranes.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: January 25, 2022
    Assignees: HORUS PHARMA, UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Marion Dubald, Sandrine Bourgeois, Hatem Fessi, Martine Claret
  • Publication number: 20220007620
    Abstract: The present invention relates to an avian model enabling the amplification of human or animal circulating tumour cells (CTC) and to the use thereof for monitoring and determining the sensitivity of a patient or an animal suffering from cancer to one or more therapeutic agent(s), as well as for screening novel therapeutic agents intended for the treatment of cancer.
    Type: Application
    Filed: October 29, 2019
    Publication date: January 13, 2022
    Applicants: INOVOTION, HOSPICES CIVILS DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1
    Inventors: Xavier ROUSSET, Emilien DOSDA, Jean VIALLET, Léa PAYEN-GAY, Denis MAILLET
  • Publication number: 20210364660
    Abstract: A multilayer scintillation detector, includes at least three layers superposed on one another, and each extending parallel to a plane, called the detection plane, wherein each layer is formed by a first material, called a scintillation material, capable of interacting with an ionizing radiation and of forming, following the interaction, a scintillation light in a scintillation spectral band; each layer has a plurality of light guides, respectively extending parallel to the detection plane, according to a length, the light guides being disposed, over all or part of their length, parallel to an axis of orientation; the axis of orientation of the light guides of each layer is oriented, in the detection plane, according to an orientation, the orientations of the respective axes of orientation of at least three layers being different from one another, such that each layer has an associated orientation; and the scintillation material has a first refractive index.
    Type: Application
    Filed: March 20, 2019
    Publication date: November 25, 2021
    Applicants: UNIVERSITE CLAUDE BERNARD LYON 1, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, HOSPICES CIVILS DE LYON, CPE LYON FORMATION CONTINUE ET RECHERCHE, ECOLE CENTRALE DE LYON
    Inventors: Patrick PITTET, Guo-Neng LU, Patrice JALADE, Jean-Marc GALVAN
  • Patent number: 11176727
    Abstract: This method for acquiring a spatial map of auditory perception of a subject comprises a plurality of successive test sequences, each test sequence comprising steps of: a) calibration (1002) of the subject's position, by displaying instructions to the subject, using a head-mounted visual display system worn by the subject, in order to acquire a reference position of the subject, the subject's position being measured using a video motion capture system by measuring the spatial coordinates of a first optical marker worn by the subject, b) choosing (1004) spatial coordinates of a target location of a sound source, said target cation being located around the subject, c) emitting (1006) a predefined sound, using a sound source placed at said target location, d) in response to acquisition instructions generated by the subject using an acquisition interface, acquiring (1008) an estimated location of said sound source, by using the video motion capture system to measure the spatial coordinates of a second optical mark
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: November 16, 2021
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE CLAUDE BERNARD LYON 1, UNIVERSITE JEAN MONNET SAINT ETIENNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Romeo Salemme, Alessandro Farne, Valérie Gaveau, Anaël Belle, Eric Koun, Francesco Pavani
  • Publication number: 20210308491
    Abstract: A therapy apparatus for treating tissue by the emission of focused ultrasound waves, including: a creation surface of a pressure field of focused ultrasound waves divided into at least N sectors having segments of asymmetrical concave curve (S1, S2, . . . ) with centres of curvature; centres of curvature (c1, c2, . . . ) asymmetrical to the extent where the centres of curvature are situated at different distances from the plane of symmetry (A1) or from the axis of symmetry (S) and/or at different depths taken according to the axis of symmetry; the individual axes (a1, a2, . . . ) intersecting between the focal zones (Zc1, Zc2, . . . ) and the creation surface (8) or beyond the focal zones such that the beams originating from the sectors intersect to create a focal coverage zone (Zr) which is off-axis relative to the plane of symmetry (A1) or to the axis of symmetry (S); the sectors of this creation surface (8) creating energy deposit zones with profiles corresponding to the focal coverage zones (Zr).
    Type: Application
    Filed: April 1, 2021
    Publication date: October 7, 2021
    Applicants: EDAP TMS FRANCE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE LEON BERARD
    Inventors: Marine SANCHEZ, David MELO DE LIMA, Jérémy VINCENOT
  • Patent number: 11136499
    Abstract: The invention relates to an aqueous composition comprising a suspension of ZnO particles and a polymer stabiliser containing carboxylic acid functions and carboxylic acid salt functions.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: October 5, 2021
    Assignees: UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stéphane Daniele, Audrey Valette, Thibaut Cornier
  • Publication number: 20210292328
    Abstract: The disclosure relates to benzoimidazole derivatives, acting as anticancer drugs, as well as pharmaceutical composition containing said compounds. These compounds are able to firstly inhibit the protein/protein interactions of the MAP Kinase Erk, leading to inhibition of proliferation and secondly to induce apoptosis in human cancer cell lines.
    Type: Application
    Filed: September 20, 2017
    Publication date: September 23, 2021
    Applicants: CENTRE LEON BERARD, HOSPICES CIVILS DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Toufic RENNO, Isabelle COSTE-INVERNIZZI, Stéphane GIRAUD, Serge LEBECQUE
  • Patent number: 11078226
    Abstract: The invention relates to novel glycosidase substrates of formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R?9, V, X, Y and Z are as defined in claim 1, and a method for detecting the presence of a catalytically active glycosidase by means of one of said substrates.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: August 3, 2021
    Assignees: ECOLE NORMALE SUPERIEURE DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jens Hasserodt, Corentin Gondrand, Maxime Prost, Gaël Yvert, Gérard Triqueneaux