Abstract: The invention relates to tetrahydroquinoline derivatives and their use in the treatment and/or the prevention of a disease wherein the Epac protein is involved, such as inflammation, cancer, vascular diseases, kidney diseases, cognitive disorders and cardiac diseases.

Abstract: An electrochemical capacitor includes a first electrode connected to a positive terminal of a power source during the charge of the electrochemical capacitor and a second electrode connected to a negative terminal of a power source during the charge of the electrochemical capacitor. The first and the second electrodes each have a carbon material. The electrochemical capacitor further includes a porous separator to separate the first and second electrodes and to be impregnated with an almost neutral aqueous electrolyte situated between the two electrodes. The neutral aqueous electrolyte has a salt formed by a metallic cation and an anion.

Abstract: The invention relates to tetrahydroquinoline derivatives and their use in the treatment and/or the prevention of a disease wherein the Epac protein is involved, such as inflammation, cancer, vascular diseases, kidney diseases, cognitive disorders and cardiac diseases.

Abstract: A method of producing a silicon/carbon composite material which includes the following successive steps: providing a silicon/polymer composite material from silicon particles and a carbonaceous polymer compound, precursor of carbon and able to be cross-linked, performing at least partial cross-linking of the polymer of the silicon/polymer composite material so as to obtain a cross-linked silicon/polymer composite material, the polymer having a cross-linking rate greater than or equal to 50% and, pyrolyzing the cross-linked silicon/polymer composite material until said silicon/carbon composite material is obtained.

Abstract: The invention relates to a method of analyzing particles, in particular particles of diameter less than 1 ?m, the method comprising the following steps: firing laser shots into a cold plasma (45) at low pressure; using an optical spectrometer device (60) to acquire emission spectra of the light emitted by the plasma as a result of the laser shots, in such a manner that for each acquired spectrum, an acquisition period begins no later than 100 ns after firing the laser shot; and analyzing the particles present in the plasma on the basis of the emission spectra. A system for detecting and/or analyzing particles by performing the method.

Abstract: The invention concerns a compound formed by functionalized micro- or nanoparticles associated covalently with rheology-modifying polymers. The invention is characterized in that the functionalized micro- or nanoparticles are functionalized micro- or nanoparticles of cerium oxide (CeO2) having a nominal diameter of between 1 and 1500 nm. The rheology-adapting or -modifying polymers are selected from among non-associative or associative polymers. The invention is used in skin protection or decontamination.

Abstract: The invention relates to a method for making a composite material including a porous polymer matrix containing HEMA monomers and in which silver nanoparticles are dispersed, and to the use thereof as an anti-microbial material.

Abstract: The invention relates to a method for producing carbon electrodes by deposition on a substrate, to produce a fuel cell. The method comprises the steps of alternately and/or simultaneously depositing porous carbon and a catalyst onto the substrate by plasma spaying in a vacuum chamber. The catalyst is used to accelerate at least one of the chemical reactions that takes place in the fuel cell. The thickness of each layer of porous carbon is chosen so that the catalyst deposited on this carbon layer is distributed essentially throughout this layer, thereby by providing a layer of catalyzed carbon. The total thickness of catalyzed carbon in the electrode is less than 2 micrometers, and preferably equal to no more than 1 micrometer.

Abstract: A method of producing a silicon/carbon composite material which includes the following successive steps: providing a silicon/polymer composite material from silicon particles and a carbonaceous polymer compound, precursor of carbon and able to be cross-linked, performing at least partial cross-linking of the polymer of the silicon/polymer composite material so as to obtain a cross-linked silicon/polymer composite material, the polymer having a cross-linking rate greater than or equal to 50% and, pyrolysing the cross-linked silicon/polymer composite material until said silicon/carbon composite material is obtained.

Abstract: The present invention relates to novel synthetic analogs of phosphatidyl-myo-inositol mannosides (hereinafter referred to as PIMs) of general formula (I): or a pharmaceutically acceptable salt thereof, to the method for preparing same and to the use thereof in the prevention or treatment of a disease associated with the overexpression of cytokines or of chemokines, in particular of TNF and/or of IL-12. The invention also relates to a pharmaceutical composition comprising at least one synthetic derivative of PIM.

Abstract: The present invention relates to a composition comprising a maxi-K potassium channel opener the use in the treatment of fragile X syndrome. More specifically the present invention relates to a composition comprising a fluoro-oxindole or a chloro-oxindole for use in the treatment of fragile X syndrome.

Abstract: Synthons for the synthesis of phosphonates prodrugs POM and POC, especially for direct Cross Metathesis.

Abstract: This invention relates to a method for determining the average surface radius ro and/or the density r of the particles of a nanopowder in a sample levitating in an electropositive plasma with a volume V formed between a first electrode powered by a radiofrequency voltage and a second electrode with a fixed voltage, in particular a ground one, characterized in that: V is the amplitude at the measuring time t of the radiofrequency voltage RF powering the first electrode when the powder is present in the plasma, V is the amplitude of said radiofrequency voltage powering the first electrode in the absence of powder in the plasma, V is the self-polarization voltage of the first electrode at the time t when the powder is present in the plasma, V is the self-polarization voltage of the first electrode in the absence of powder in the plasma, ?AB is the surface variation of the second electrode in the presence of powder at the time t relative to a situation in which powder is absent, and the values of n and K are dete

Abstract: The invention relates to a static copolymer of linear polyethylenimine that comprises two monomer units of the following formulas I and II, in which R1 is a hydrogen atom or a C1-C6 alkyl radical, R2 is a hydrogen atom, a C1-C6 alkyl, aryl or aralkyl group, wherein the alkyl group is a C1-C6 one, n is a number between 1 and 99% of the total monomers, m is a number between 1 and 99% of the total monomers, and advantageously m+n=100%. The invention also relates to complexes of this copolymer with a nucleic acid, and to the use thereof in in vivo, in vitro or ex vivo gene transfection.

Abstract: An electrochemical capacitor includes a first electrode connected to a positive terminal of a power source during the charge of the electrochemical capacitor and a second electrode connected to a negative terminal of a power source during the charge of the electrochemical capacitor. The first and the second electrodes each have a carbon material. The electrochemical capacitor further includes a porous separator to separate the first and second electrodes and to be impregnated with an almost neutral aqueous electrolyte situated between the two electrodes. The neutral aqueous electrolyte has a salt formed by a metallic cation and an anion.

Abstract: A new device based on very short pulsed discharges, generating plasmas balls and plumes over very long distances (up to several meters). These plasma balls travel in a dielectric guide at the end of which there is generation of an apparent plasma plume like zone, with a shape and intensity dependent on the discharge repetition rate. A secondary mixture plasma can be produced close to a given surface by adding other gas fluxes in the main gas stream. The plasma balls can be generated in gases at a repetition rate in the range from single shot to multi-kilohertz.

Abstract: A method for measuring the viscosity of any liquid gaseous or supercritical, optionally multiphase fluid, under extended conditions of pressure, temperature and chemical composition, the method is based on the application of a flow law of the fluid through a permeable medium, the permeability of which is known. A viscosimeter for carrying out this measurement method is also described.

Abstract: A system of computation tools sharing, the computing tools having been used to generate results presented in scientific publications, includes a computing tool being composed of a source code and a program execution tool whose function is to execute the program described by the said source code, and at least one server being used to memorize the computing tools, the computing tools being accessible remotely by an accessing user by the use of an Internet portal, the access to a computing tool through the Internet portal being linked to the scientific publication for which it has been used to generate results.

Abstract: The present invention relates to a compound of the following general formula (I): wherein: R1 is notably H, a halogen or an aryl group, R2 is notably a halogen or an aryl group, R3 is notably a halogen, or an aryl or heteroaryl group, as well as to its pharmaceutically acceptable salts, its hydrates or its polymorphic crystalline structures, its racemates, diastereoisomers or enantiomers, except the compound 1-(2,4-diaminopyrido[3,2-d]pyrimidin-7-yl)-3,6,6-trimethyl-6,7-dihydro-1H-indol-4(5H)-one.

Abstract: This invention relates to a method for determining the average surface radius ro and/or the density r of the particles of a nanopowder in a sample levitating in an electropositive plasma with a volume V formed between a first electrode powered by a radiofrequency voltage and a second electrode with a fixed voltage, in particular a ground one, characterised in that: V is the amplitude at the measuring time t of the radiofrequency voltage RF powering the first electrode when the powder is present in the plasma, V is the amplitude of said radiofrequency voltage powering the first electrode in the absence of powder in the plasma, V is the self-polarisation voltage of the first electrode at the time t when the powder is present in the plasma, V is the self-polarisation voltage of the first electrode in the absence of powder in the plasma, ?AB is the surface variation of the second electrode in the presence of powder at the time t relative to a situation in which powder is absent, and the values of n and K are dete