Abstract: The present invention relates to compounds having the following general formula (I): wherein: A represents a SO2 or CX group, X representing O or S; R1, R2, R?, R4 represent in particular H, R represents in particular an alkyl group or an aryl group, as well as to the pharmaceutically acceptable salts thereof, the compound of formula (I) taking the form of a pure stereoisomer or an enantiomer and/or diastereoisomer mixture, including racemic mixtures.
Type:
Application
Filed:
March 11, 2010
Publication date:
April 19, 2012
Applicants:
UNIVERSITE D'ORLEANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
Inventors:
Sylvain Cesar Leonce Routier, Gerald Guillaumet, Rajaa Boulahjar, Laurent Meijer, Matteo Chiurato
Abstract: The present invention relates to a method for extracting organic molecules and/or organic minerals from a limestone material, including placing said limestone material in contact with a solution including at least one organic solvent, water and at least one acid, as well as to the organic molecules and/or organic minerals produced by the method. The products produced by the method can be used, for example, in therapeutic and non-therapeutic fields, in particular the agri-food, cosmetic and medical fields.
Type:
Application
Filed:
April 9, 2010
Publication date:
March 22, 2012
Applicants:
Centre National De La Recherche Scientifique-CNRS-, Universite D'Orleans, Museum National D'Histoire Naturelle
Abstract: A system (1) for analyzing solid particles in a medium (2), includes illumination elements (3) capable of generating a light field (30) in the medium (2), elements (4) for trapping at least a portion (30?) of the light field (30) generated and arranged in the direction (31) of the light field, and main detection element (5) for detecting the light field (30?) diffused by the solid particles within the medium (2). The main detection element includes a photodetector (52) for the light field (30?) diffused by the solid particles in the medium and a counter (53) for counting these solid particles in this medium, this main detection element being positioned in a direction (51) forming an angle (?) substantially ranging between 10° and 20° with respect to the direction of the light field generated. A method for analyzing solid particles in a medium implementing such an analysis system is described.
Type:
Application
Filed:
November 17, 2009
Publication date:
December 22, 2011
Applicants:
ENVIRONNEMENT S.A., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CNRS, UNIVERSITE D'ORLEANS
Abstract: A composite suitable as a charge-storing material for electrochemical capacitors contains carbon nanotubes and a carbonaceous materiel. The carbonaceous material is the carbonization residue of a biopolymer or seaweed rich in heteroatoms. Wherein the carbonization residue of the biopolymer or seaweed is electrically conductive and has a heteroatom content as detected by XPS of at least 6%.
Type:
Grant
Filed:
August 17, 2009
Date of Patent:
November 15, 2011
Assignees:
SGL Carbon SE, Centre National de la Recherche Scientifique, L'Universite d'Orleans
Inventors:
Martin Cadek, Mario Wachtler, Encarnacion Raymundo-Pinero, Francois Beguin
Abstract: The present invention relates to novel synthetic analogues of phosphatidyl-myo-inositol mannosides (hereinafter referred to as PIMs) of general formula (I): or a pharmaceutically acceptable salt thereof, to the method for preparing same and to the use thereof in the prevention or treatment of a disease associated with the overexpression of cytokines or of chemokines, in particular of TNF and/or of IL-12. The invention also relates to a pharmaceutical composition comprising at least one synthetic derivative of PIM.
Type:
Application
Filed:
May 20, 2009
Publication date:
September 15, 2011
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS-, UNIVERSITE D'ORLEANS
Inventors:
Valérie Quesniaux Fyffel, Olivier Martin, Sophie Front
Abstract: A carbon material suitable for the preparation of electrodes for electrochemical capacitors is obtained by single-stage carbonization of biopolymers with a large content of heteroatoms. Neither addition of an activating agent during carbonization nor subsequent gas phase activation is necessary. Several biopolymers which are available by extraction from seaweed are suitable precursors. Alternatively, the seaweed containing such biopolymers is carbonized directly.
Type:
Grant
Filed:
August 1, 2008
Date of Patent:
May 24, 2011
Assignees:
SGL Carbon SE, Centre National de la Recherche Sientifique, L'Universite d'Orleans
Inventors:
Martin Cadek, Francois Beguin, Encarnacion Raymundo-Pinero
Abstract: An electrolytic capacitor (1) includes a first electrode (2) and a second electrode (3) each including carbon and an aqueous electrolyte (4) situated at the interface of the two electrodes. The carbon surface of the first electrode (2) has an atomic degree of functionalization which is at least twice that of the carbon surface of the second electrode (3).
Type:
Grant
Filed:
November 30, 2007
Date of Patent:
May 3, 2011
Assignees:
Centre National de la Recherche Scientifique (C.N.R.S.), Universite d'Orleans
Abstract: The invention relates to a method for making a composite material including a porous polymer matrix containing HEMA monomers and in which silver nanoparticles are dispersed, and to the use thereof as an anti-microbial material.
Type:
Application
Filed:
February 3, 2009
Publication date:
March 3, 2011
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'ORLEANS
Inventors:
Roland Benoit, Marie-Louise Saboungi, Fabienne Brulé
Abstract: An electrolytic capacitor (1) includes a first electrode (2) and a second electrode (3) each including carbon and an aqueous electrolyte (4) situated at the interface of the two electrodes. The carbon surface of the first electrode (2) has an atomic degree of functionalization which is at least twice that of the carbon surface of the second electrode (3).
Type:
Application
Filed:
November 30, 2007
Publication date:
June 10, 2010
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE D'ORLEANS
Abstract: A composite suitable as a charge-storing material for electrochemical capacitors contains carbon nanotubes and a carbonaceous materiel. The carbonaceous material is the carbonization residue of a biopolymer or seaweed rich in heteroatoms. Wherein the carbonization residue of the biopolymer or seaweed is electrically conductive and has a heteroatom content as detected by XPS of at least 6%.
Type:
Application
Filed:
August 17, 2009
Publication date:
February 11, 2010
Applicants:
SGL CARBON SE, CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE, L'UNIVERSITÉ D'ORLÉANS
Inventors:
Martin Cadek, Mario Wachtler, Encarnacion Raymundo-Pinero, Francois Beguin
Abstract: The present invention relates to a process for depositing a thin film of a metal alloy on a substrate, said film comprising at least four components and said alloy being either: an amorphous alloy containing 50 at % of the elements Ti and Zr, or a high-entropy alloy, the elements of which are chosen from the group consisting of Al, Co, Cr, Cu, Fe, Ni, Si, Mn, Mo, V, Zr and Ti; by simultaneous magnetron sputtering of at least two targets. The present invention also relates to a metal alloy in the form of a thin film comprising at least four components, which can be deposited on a substrate by implementing the process.
Abstract: A carbon material suitable for the preparation of electrodes for electrochemical capacitors is obtained by single-stage carbonization of biopolymers with a large content of heteroatoms. Neither addition of an activating agent during carbonization nor subsequent gas phase activation is necessary. Several biopolymers which are available by extraction from seaweed are suitable precursors. Alternatively, the seaweed containing such biopolymers is carbonized directly.
Type:
Application
Filed:
August 1, 2008
Publication date:
February 26, 2009
Applicants:
SGL CARBON AG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, L'UNIVERSITE D'ORLEANS
Inventors:
Martin Cadek, Francois Beguin, Encarnacion Raymundo-Pinero
Abstract: The invention concerns a radiation source, comprising an anode (2), a cathode (3), an electric discharge gap (4) between the anode (2) and the cathode (3) and a gas input conduit (30) in the discharge gap (4). The gas input conduit (30) is electrically connected to the anode and the cathode. The invention is characterized in that the gas input conduit (30) is supplied with gas by a gas supply conduit (32), designed to form between its portion (42) connected to the gas input conduit (30) and another of its portions connected to a fixed potential, an electric impedance such that it counters the generation of electric discharges inside the gas input conduit (30).
Type:
Grant
Filed:
June 27, 2003
Date of Patent:
September 2, 2008
Assignees:
Centre National de la Recherche Scientifique (C.N.R.S.), Universite d'Orleans
Inventors:
Christophe Cachoncinlle, Rémi Dussart, Claude Fleurier, Jean-Michel Pouvesle, Eric Robert, Raymond Viladrosa
Abstract: A method of separating and analyzing slightly volatile cations and/or anions contained in a sample immediately and simultaneously. The sample is injected into a chromatography device in liquid phase co-operating with at least one stationary phase likely to retain the cations and the anions contained in the sample by competing interactions with the stationary phase or phases. The cations and anions are eluted by feeding at least one mobile phase which can be evaporated through the stationary phase or phases. The cations and the anions present in the mobile phase or phases are analyzed with the aid of an evaporative light scattering detector.
Type:
Grant
Filed:
December 15, 1998
Date of Patent:
November 21, 2000
Assignees:
Sedere S.A., Universite d'Orleans-UFR de Sciences
Abstract: The drug contains an active substance consisting of 1-(3'-benzofuryl)-4-benzylpiperazine. In order to prepare the compound, a reaction is carried out with reflux between 3-coumaranone and N-benzylpiperazine in the presence of acetic acid and in an aromatic solvent.
Type:
Grant
Filed:
January 29, 1981
Date of Patent:
May 10, 1983
Assignees:
Andre Buzas, Jean-Marie Melon, Laboratoires Sauba S.A., Universite d'Orleans
Inventors:
Andre Buzas, Jean-Marie Melon, Gilbert Lavielle, Andre Champagnac
Abstract: The disubstituted 2,5-benzamides correspond to the following general formula: ##STR1## where R is an alkyl group (possessing 1 to 5 carbon atom) or an allyl group, ##STR2## represents one of the following groups: phenylpiperazine, benzylpiperazine, piperonylpiperazine, dimethylaminoethylamino, diethylaminoethylamino, pyrrolidinyl-1 substituted methylamino, morpholine or piperidine, R' is an alkyl possessing 1 to 8 carbon atoms, a phenyl, or substituted phenyl, an alpha-aminomethyl or acrylic group, Y is an oxygen atom, an oxime, oxime ether, oxime ester or imine group.