Patents Assigned to Universite de Lorraine
  • Patent number: 12149150
    Abstract: The present invention relates to a superconducting pellet for a superconducting electrical machine, the superconducting pellet having a circumferential wall, the circumferential wall having: a first border, a second border opposite the first border, an inner face connecting the first border to the second border, an outer face opposite the inner face, and a cavity formed between the first border and the second border and defined by the inner face, and an additional wall which covers the first border or is flush with the first border so as to at least partially cover the cavity, or extends from the inner face at a distance from the first border and the second border so as to divide the cavity into two portions.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: November 19, 2024
    Assignees: SAFRAN, UNIVERSITE DE LORRAINE
    Inventors: Sabrina Siham Ayat, Alexandre Colle, Rémy Biaujaud
  • Publication number: 20240335375
    Abstract: An ocular delivery system useful for the treatment of glaucoma in subject in need thereof. Especially, a mucoadhesive solid or semisolid ocular delivery system that includes a matrix of preactivated thiomer of hyaluronic acid and one or more anti-glaucoma drugs. The ocular delivery system may be an ocular insert or an ocular film.
    Type: Application
    Filed: August 3, 2022
    Publication date: October 10, 2024
    Applicants: BIOADHESIVE OPHTHALMICS, UNIVERSITÉ DE LORRAINE
    Inventors: Jean CUINE, Boris BIZET, Frédéric LALLEMAND, Jean GARREC, Stéphane GIBAUD, Anne SAPIN-MINET
  • Publication number: 20240292851
    Abstract: Strains of Carnobacterium maltaromaticum, a bacterial preparation including at least one strain of Carnobacterium maltaromaticum, and their use in the preparation of a food product. Also, a method for reducing microbial contamination during a process for the production of a fermented milk product to which a quantity of Carnobacterium maltaromaticum or a bacterial preparation including at least one strain of Carnobacterium maltaromaticum is added.
    Type: Application
    Filed: October 14, 2020
    Publication date: September 5, 2024
    Applicant: UNIVERSITE DE LORRAINE
    Inventors: Frédéric BORGES, Anne-Marie REVOL-JUNELLES
  • Publication number: 20240245732
    Abstract: The disclosure relates to human mesenchymal stem cells from Wharton's jelly, a method for preparing them, and the therapeutic uses thereof, in particular for the treatment of sepsis and specifically septic shock. The treatment may involve the administration to a subject in need thereof a pharmaceutical composition including the human mesenchymal stem cells from Wharton's jelly and a pharmaceutically acceptable excipient.
    Type: Application
    Filed: March 19, 2024
    Publication date: July 25, 2024
    Applicants: UNIVERSITÉ DE LORRAINE, CENTRE HOSPITALIER RÉGIONAL UNIVERSITAIRE DE NANCY
    Inventors: Danièle BENSOUSSAN, Sébastien GIBOT, Loïc REPPEL, Caroline LAROYE, Amir BOUFENZER, Léonore AVERCENC, Céline HUSELSTEIN
  • Publication number: 20240238336
    Abstract: Copper nanoclusters designated by the formula “CuNC@HisAc” or “CuNC@HisAcAsc”, wherein the copper nanoclusters: are covered on the surface thereof by a mixed layer including histidine (His), acetate ions (Ac) and possibly ascorbate ions (Asc); have a spherical shape; have a hydrodynamical diameter of 0.6-2.0 nm; have a metallic core with a diameter of 0.5-1.5 nm; have a temporal stability of 5-12 weeks in solution; have a temporal stability of at least 12 months in dried form; and have spectrophotometric properties, with a shoulder in the UV-Visible spectrum at 325±10 nm and a fluorescence spectrum with excitation wavelengths of 365-395 nm and emission wavelengths of 445-475 nm. Also, a method for preparation of the copper nanoclusters, and the use of the copper nanoclusters in a method treatment of pathologies related to a copper deficit, and in particular Menkes syndrome.
    Type: Application
    Filed: May 10, 2022
    Publication date: July 18, 2024
    Applicants: UNIVERSITÉ DE LORRAINE, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE NANCY (CHRU)
    Inventors: Ariane BOUDIE, Igor CLAROT, François FEILLET
  • Publication number: 20240230538
    Abstract: The facility for detecting at least one characteristic parameter of a medium (M), has as device (3) illuminating the medium (M) with a visible polychromatic light, a device (4) exciting the medium (M) with a visible-light or infrared monochromatic radiation, a first device (5) collecting and conveying at least a first electromagnetic radiation emitted by the medium (M), a second device (6) collecting and conveying at least a second electromagnetic radiation emitted by the medium (M), at least one visible-band spectrometer (7) obtaining at least one visible-band spectrum of the medium (M) from the at least first electromagnetic radiation, at least one Raman spectrometer (8) obtaining at least one Raman spectrum of the medium (M) from the at least second electromagnetic radiation, and a device (9) detecting the at least one characteristic parameter from the at least one visible-band spectrum and the at least one Raman spectrum.
    Type: Application
    Filed: May 2, 2022
    Publication date: July 11, 2024
    Applicants: CENTRALESUPELEC, UNIVERSITE DE LORRAINE
    Inventors: Patrick Perre, Ninel Kokanyan, Cédric Guérin, Mahamadou Mounkaila, Emilie Michiels, Victor Pozzobon
  • Patent number: 11963984
    Abstract: The disclosure relates to human mesenchymal stem cells from Wharton's jelly, a method for preparing them, and the therapeutic uses thereof, in particular for the treatment of sepsis and specifically septic shock. The treatment may involve the administration to a subject in need thereof a pharmaceutical composition including the human mesenchymal stem cells from Wharton's jelly and a pharmaceutically acceptable excipient.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: April 23, 2024
    Assignees: UNIVERSITÉ DE LORRAINE, CENTRE HOSPITALIER RÉGIONAL UNIVERSITAIRE DE NANCY
    Inventors: Danièle Bensoussan, Sébastien Gibot, Loïc Reppel, Caroline Laroye, Amir Boufenzer, Léonore Avercenc, Céline Huselstein
  • Patent number: 11964407
    Abstract: A flame retardant treatment of a lignocellulosic material, which includes: optionally steam exploding the lignocellulosic material, impregnating the optionally steam-exploded lignocellulosic material, in or with an aqueous solution, from 0.5% to 10% of phytic acid and from 1% to 30% of urea, based on the total weight of the aqueous solution, optionally drying of the impregnated lignocellulosic material, until the impregnated lignocellulosic material has a moisture content from 5% to 20% by weight, cooking the impregnated and optionally dried lignocellulosic material, the resulting flame-retarded lignocellulosic material including a phosphorous content originating from the phytic acid from 0.1% to 10% by weight.
    Type: Grant
    Filed: April 8, 2021
    Date of Patent: April 23, 2024
    Assignees: UNIVERSITE DE LORRAINE, INSTITUT MINES TELECOM, UNIVERSITE LIBANAISE
    Inventors: Nicolas Brosse, Romain Kapel, Rodolphe Sonnier, Roland El Hage, César Segovia, Karina Antoun, Maria Moussa
  • Publication number: 20240097548
    Abstract: This invention relates to a superconducting electric machine (1), for example with axial flux or with radial flux, comprising an inductor (3) comprising superconducting pellets (7) circumferentially distributed around an axis (X) of the electric machine (1) and a flux barrier (12) comprising a superconducting material, said flux barrier (12) being centered on the axis (X) of rotation and extending radially inward of the superconducting pellets (7).
    Type: Application
    Filed: January 18, 2022
    Publication date: March 21, 2024
    Applicants: SAFRAN, UNIVERSITE DE LORRAINE
    Inventors: Sabrina Siham AYAT, Rémi Luc Stéphane DORGET, Benjamin DAGUSE
  • Publication number: 20240097549
    Abstract: The present invention relates to a superconducting electric machine (1) comprising an inductor (3) having: —superconducting pellets (7) circumferentially distributed about an axis (X) of the electric machine (1), —an armature (2) comprising coils (5), each coil (5) having a circumferential radially inner edge (10) and a circumferential radially outer edge (9), and—at least one flow barrier (12, 12?) extending circumferentially with respect to the axis (X), each flow barrier (12) extending between the superconducting pellets (7) and the armature (2) so as to at least partially cover at least one of the radially outer edge (9) and the radially inner edge (10) of all or part of the coils (5) of the armature (2).
    Type: Application
    Filed: January 13, 2022
    Publication date: March 21, 2024
    Applicants: SAFRAN, UNIVERSITE DE LORRAINE
    Inventors: Sabrina Siham AYAT, Rémi Luc Stéphane DORGET, Benjamin DAGUSE
  • Patent number: 11935665
    Abstract: The present invention relates to a process for treating aqueous effluents from the primary circuit of a nuclear power plant implementing a separation of boric acid using a reverse osmosis membrane, characterized by the fact that it comprises steps consisting of treating the effluents using a multi-stage assembly composed of reverse osmosis modules comprising a membrane with a high boron rejection rate, arranged in parallel and in series, and recycling of the intermediate products to different points in the assembly.
    Type: Grant
    Filed: December 4, 2019
    Date of Patent: March 19, 2024
    Assignees: Electricite de France, Centre National de la Recherche Scientifique (CNRS), Universite de Lorraine
    Inventors: Thibaut Neveux, Eve Bailleul, Christophe Castel, Eric Favre
  • Patent number: 11933926
    Abstract: A device for radioactivity counting and characterization for a solution. The device includes a container having at least two recesses, a first recess for receiving a vial and a second recess for receiving a radioactivity sensor, a radioactivity sensor having a semiconductor sensor presenting a cone of detection directed to the first recess of the container for receiving a vial, a removable closure element, an armored cover around the container and its upper face, the upper face of the armored cover having an opening for introducing the vial into the container and a plate for supporting the device.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: March 19, 2024
    Assignee: UNIVERSITE DE LORRAINE
    Inventors: Guénolé Mathias-Laot, Quentin Thomas
  • Patent number: 11832633
    Abstract: A process for producing a protein isolate from an oilseed meal, and the isolate thus obtained, said isolate comprising proteins and an amount of 4 wt. % or less of phytic acid, said amount of phytic acid being by weight of proteins in said isolate. The process may comprise the following steps: a) providing an oilseed meal; b) mixing the oilseed meal with a first aqueous solvent to form a slurry at a pH ranging from 6 to 7.8, said slurry having a solid phase; c) separating said solid phase from said slurry, d) mixing said separated solid phase with a second aqueous solvent at a pH ranging from 1 to 3.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: December 5, 2023
    Assignees: AVRIL, UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Claire Defaix, Romain Kapel, Olivier Galet
  • Patent number: 11838530
    Abstract: A method for concealing data in an image or a video stream inside a compression chain, being implemented by a computer and including a structuring and processing phase, during which at least one image is structured into blocks including coefficients, a phase of converting and quantifying blocks so as to generate converted and quantified coefficients, with entropic coding intended to code the converted and quantified coefficients. The method includes a step of concealing data, during which bits of the data are concealed by modifying converted and quantified coefficients located in a high frequency zone of at least some of the blocks that relate to the luminance component of the video stream and that are intra-coded. This modification is performed after the quantification but before the entropic coding.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: December 5, 2023
    Assignees: UNIVERSITE DE LORRAINE, UNIVERSITE DE STRASBOURG
    Inventors: Jean-Marie Moureaux, Amine Chaabouni, Yann Gaudeau
  • Publication number: 20230273208
    Abstract: The use of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) as a marker in a method for identifying a subject suffering from a disease caused by a coronavirus such as COVID-19 at risk of having or developing a severe form and/or a complication or at risk of death, in a method for assessing the severity of a disease caused by a coronavirus such as COVID-19, and in a method for monitoring a subject suffering from a disease caused by a coronavirus such as COVID-19.
    Type: Application
    Filed: June 7, 2021
    Publication date: August 31, 2023
    Applicants: INOTREM, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE NANCY, UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM
    Inventors: Jean-Jacques GARAUD, Marc DERIVE, Margarita SALCEDO-MAGGUILLI, Lucie JOLLY, Sébastien GIBOT, David MOULIN, Mihai NETEA, Aline DE NOOIJER
  • Patent number: 11712744
    Abstract: An electrolyte for the electrochemical machining of a ?-?? nickel-based superalloy, includes NaNO3 in a content of between 10% and 30% by weight relative to the total weight of the electrolyte; a complexing agent selected from sulfosalicylic acid at a pH of between 3 and 10 and nitrilotriacetic acid at a pH of between 7 and 14, the complexing agent being present in a content of between 1% and 5% by weight relative to the total weight of the electrolyte; optionally, an anionic surfactant in a content of between 1% and 5% by weight relative to the total weight of the electrolyte; optionally, NaOH in order to obtain the desired pH; and an aqueous solvent.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: August 1, 2023
    Assignees: SAFRAN AIRCRAFT ENGINES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LORRAINE
    Inventors: Mariem Msakni Malouche, Janvier Lecomte, Mickael Rancic, Nicolas Stein, Clotilde Boulanger
  • Publication number: 20230182342
    Abstract: A flame retardant treatment of a lignocellulosic material, which includes: optionally steam exploding the lignocellulosic material, impregnating the optionally steam-exploded lignocellulosic material, in or with an aqueous solution, from 0.5% to 10% of phytic acid and from 1% to 30% of urea, based on the total weight of the aqueous solution, optionally drying of the impregnated lignocellulosic material, until the impregnated lignocellulosic material has a moisture content from 5% to 20% by weight, cooking the impregnated and optionally dried lignocellulosic material, the resulting flame-retarded lignocellulosic material including a phosphorous content originating from the phytic acid from 0.1% to 10% by weight.
    Type: Application
    Filed: April 8, 2021
    Publication date: June 15, 2023
    Applicants: UNIVERSITE DE LORRAINE, INSTITUT MINES TELECOM, UNIVERSITE LIBANAISE
    Inventors: Nicolas BROSSE, Romain KAPEL, Rodolphe SONNIER, Roland EL HAGE, César SEGOVIA, Karina ANTOUN, Maria MOUSSA
  • Patent number: 11667873
    Abstract: The present invention relates to an enzymatic method for removing sulphite. In particular, the present invention relates to a method for converting sulphite present in a composition into thiosulphate, comprising the introduction of 3-mercaptopyruvate sulphurtransferase (3-MST) and a substrate of said 3-mercaptopyruvate sulphurtransferase into said composition. The present invention can be used in particular in the pharmaceutical, cosmetic, food and chemical fields, and any field involving the use of sulphite.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: June 6, 2023
    Assignee: UNIVERSITÉ DE LORRAINE
    Inventors: Jean-Christophe Lec, Alexandre Kriznik, François Talfournier, Sandrine Boschi
  • Patent number: 11661446
    Abstract: The present invention relates to a novel method for the affinity purification of proteins of interest in a single step, based on the lectin activity of the CRD (Carbohydrate Recognition Domain) of a galectin or part of said domain retaining the ability to bind ?-galactosidase derivative.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: May 30, 2023
    Assignees: UNIVERSITÉ DE LORRAINE, CENTRE HOSPITALIER RÉGIONAL DE NANCY
    Inventors: Alexandre Kriznik, Pascal Saim Reboul, Mélissa Jenner Yelehe-Okouma
  • Publication number: 20230147036
    Abstract: Disclosed is a rotating electrical machine with axial air gap, comprising two rotors, each provided with superconducting axial magnetic flux barrier elements around an axis of rotation and having, between them, axial magnetic flux passage areas, at least one armature, comprising windings and a superconducting field coil surrounding the elements and the armature and capable of inducing an axial magnetic field. Each armature is positioned between two of the rotors. The superconducting elements of the rotors are coaxial with one another and also the flux passage areas. A first annular cryogenic enclosure encloses the field coil and a second cryogenic enclosure encloses the two rotors and the armature or only one rotor, with a third cryogenic enclosure around the other rotor without the armature.
    Type: Application
    Filed: March 11, 2021
    Publication date: May 11, 2023
    Applicants: UNIVERSITE DE LORRAINE, SAFRAN
    Inventors: Alexandre COLLE, Sabrina Siham AYAT, Rémy BIAUJAUD