Patents Assigned to Universite de Lorraine
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Patent number: 12149150Abstract: The present invention relates to a superconducting pellet for a superconducting electrical machine, the superconducting pellet having a circumferential wall, the circumferential wall having: a first border, a second border opposite the first border, an inner face connecting the first border to the second border, an outer face opposite the inner face, and a cavity formed between the first border and the second border and defined by the inner face, and an additional wall which covers the first border or is flush with the first border so as to at least partially cover the cavity, or extends from the inner face at a distance from the first border and the second border so as to divide the cavity into two portions.Type: GrantFiled: December 7, 2020Date of Patent: November 19, 2024Assignees: SAFRAN, UNIVERSITE DE LORRAINEInventors: Sabrina Siham Ayat, Alexandre Colle, Rémy Biaujaud
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Publication number: 20240335375Abstract: An ocular delivery system useful for the treatment of glaucoma in subject in need thereof. Especially, a mucoadhesive solid or semisolid ocular delivery system that includes a matrix of preactivated thiomer of hyaluronic acid and one or more anti-glaucoma drugs. The ocular delivery system may be an ocular insert or an ocular film.Type: ApplicationFiled: August 3, 2022Publication date: October 10, 2024Applicants: BIOADHESIVE OPHTHALMICS, UNIVERSITÉ DE LORRAINEInventors: Jean CUINE, Boris BIZET, Frédéric LALLEMAND, Jean GARREC, Stéphane GIBAUD, Anne SAPIN-MINET
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Publication number: 20240292851Abstract: Strains of Carnobacterium maltaromaticum, a bacterial preparation including at least one strain of Carnobacterium maltaromaticum, and their use in the preparation of a food product. Also, a method for reducing microbial contamination during a process for the production of a fermented milk product to which a quantity of Carnobacterium maltaromaticum or a bacterial preparation including at least one strain of Carnobacterium maltaromaticum is added.Type: ApplicationFiled: October 14, 2020Publication date: September 5, 2024Applicant: UNIVERSITE DE LORRAINEInventors: Frédéric BORGES, Anne-Marie REVOL-JUNELLES
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Publication number: 20240245732Abstract: The disclosure relates to human mesenchymal stem cells from Wharton's jelly, a method for preparing them, and the therapeutic uses thereof, in particular for the treatment of sepsis and specifically septic shock. The treatment may involve the administration to a subject in need thereof a pharmaceutical composition including the human mesenchymal stem cells from Wharton's jelly and a pharmaceutically acceptable excipient.Type: ApplicationFiled: March 19, 2024Publication date: July 25, 2024Applicants: UNIVERSITÉ DE LORRAINE, CENTRE HOSPITALIER RÉGIONAL UNIVERSITAIRE DE NANCYInventors: Danièle BENSOUSSAN, Sébastien GIBOT, Loïc REPPEL, Caroline LAROYE, Amir BOUFENZER, Léonore AVERCENC, Céline HUSELSTEIN
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Publication number: 20240238336Abstract: Copper nanoclusters designated by the formula “CuNC@HisAc” or “CuNC@HisAcAsc”, wherein the copper nanoclusters: are covered on the surface thereof by a mixed layer including histidine (His), acetate ions (Ac) and possibly ascorbate ions (Asc); have a spherical shape; have a hydrodynamical diameter of 0.6-2.0 nm; have a metallic core with a diameter of 0.5-1.5 nm; have a temporal stability of 5-12 weeks in solution; have a temporal stability of at least 12 months in dried form; and have spectrophotometric properties, with a shoulder in the UV-Visible spectrum at 325±10 nm and a fluorescence spectrum with excitation wavelengths of 365-395 nm and emission wavelengths of 445-475 nm. Also, a method for preparation of the copper nanoclusters, and the use of the copper nanoclusters in a method treatment of pathologies related to a copper deficit, and in particular Menkes syndrome.Type: ApplicationFiled: May 10, 2022Publication date: July 18, 2024Applicants: UNIVERSITÉ DE LORRAINE, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE NANCY (CHRU)Inventors: Ariane BOUDIE, Igor CLAROT, François FEILLET
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Publication number: 20240230538Abstract: The facility for detecting at least one characteristic parameter of a medium (M), has as device (3) illuminating the medium (M) with a visible polychromatic light, a device (4) exciting the medium (M) with a visible-light or infrared monochromatic radiation, a first device (5) collecting and conveying at least a first electromagnetic radiation emitted by the medium (M), a second device (6) collecting and conveying at least a second electromagnetic radiation emitted by the medium (M), at least one visible-band spectrometer (7) obtaining at least one visible-band spectrum of the medium (M) from the at least first electromagnetic radiation, at least one Raman spectrometer (8) obtaining at least one Raman spectrum of the medium (M) from the at least second electromagnetic radiation, and a device (9) detecting the at least one characteristic parameter from the at least one visible-band spectrum and the at least one Raman spectrum.Type: ApplicationFiled: May 2, 2022Publication date: July 11, 2024Applicants: CENTRALESUPELEC, UNIVERSITE DE LORRAINEInventors: Patrick Perre, Ninel Kokanyan, Cédric Guérin, Mahamadou Mounkaila, Emilie Michiels, Victor Pozzobon
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Patent number: 11963984Abstract: The disclosure relates to human mesenchymal stem cells from Wharton's jelly, a method for preparing them, and the therapeutic uses thereof, in particular for the treatment of sepsis and specifically septic shock. The treatment may involve the administration to a subject in need thereof a pharmaceutical composition including the human mesenchymal stem cells from Wharton's jelly and a pharmaceutically acceptable excipient.Type: GrantFiled: February 28, 2018Date of Patent: April 23, 2024Assignees: UNIVERSITÉ DE LORRAINE, CENTRE HOSPITALIER RÉGIONAL UNIVERSITAIRE DE NANCYInventors: Danièle Bensoussan, Sébastien Gibot, Loïc Reppel, Caroline Laroye, Amir Boufenzer, Léonore Avercenc, Céline Huselstein
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Patent number: 11964407Abstract: A flame retardant treatment of a lignocellulosic material, which includes: optionally steam exploding the lignocellulosic material, impregnating the optionally steam-exploded lignocellulosic material, in or with an aqueous solution, from 0.5% to 10% of phytic acid and from 1% to 30% of urea, based on the total weight of the aqueous solution, optionally drying of the impregnated lignocellulosic material, until the impregnated lignocellulosic material has a moisture content from 5% to 20% by weight, cooking the impregnated and optionally dried lignocellulosic material, the resulting flame-retarded lignocellulosic material including a phosphorous content originating from the phytic acid from 0.1% to 10% by weight.Type: GrantFiled: April 8, 2021Date of Patent: April 23, 2024Assignees: UNIVERSITE DE LORRAINE, INSTITUT MINES TELECOM, UNIVERSITE LIBANAISEInventors: Nicolas Brosse, Romain Kapel, Rodolphe Sonnier, Roland El Hage, César Segovia, Karina Antoun, Maria Moussa
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Publication number: 20240097548Abstract: This invention relates to a superconducting electric machine (1), for example with axial flux or with radial flux, comprising an inductor (3) comprising superconducting pellets (7) circumferentially distributed around an axis (X) of the electric machine (1) and a flux barrier (12) comprising a superconducting material, said flux barrier (12) being centered on the axis (X) of rotation and extending radially inward of the superconducting pellets (7).Type: ApplicationFiled: January 18, 2022Publication date: March 21, 2024Applicants: SAFRAN, UNIVERSITE DE LORRAINEInventors: Sabrina Siham AYAT, Rémi Luc Stéphane DORGET, Benjamin DAGUSE
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Publication number: 20240097549Abstract: The present invention relates to a superconducting electric machine (1) comprising an inductor (3) having: —superconducting pellets (7) circumferentially distributed about an axis (X) of the electric machine (1), —an armature (2) comprising coils (5), each coil (5) having a circumferential radially inner edge (10) and a circumferential radially outer edge (9), and—at least one flow barrier (12, 12?) extending circumferentially with respect to the axis (X), each flow barrier (12) extending between the superconducting pellets (7) and the armature (2) so as to at least partially cover at least one of the radially outer edge (9) and the radially inner edge (10) of all or part of the coils (5) of the armature (2).Type: ApplicationFiled: January 13, 2022Publication date: March 21, 2024Applicants: SAFRAN, UNIVERSITE DE LORRAINEInventors: Sabrina Siham AYAT, Rémi Luc Stéphane DORGET, Benjamin DAGUSE
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Patent number: 11935665Abstract: The present invention relates to a process for treating aqueous effluents from the primary circuit of a nuclear power plant implementing a separation of boric acid using a reverse osmosis membrane, characterized by the fact that it comprises steps consisting of treating the effluents using a multi-stage assembly composed of reverse osmosis modules comprising a membrane with a high boron rejection rate, arranged in parallel and in series, and recycling of the intermediate products to different points in the assembly.Type: GrantFiled: December 4, 2019Date of Patent: March 19, 2024Assignees: Electricite de France, Centre National de la Recherche Scientifique (CNRS), Universite de LorraineInventors: Thibaut Neveux, Eve Bailleul, Christophe Castel, Eric Favre
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Patent number: 11933926Abstract: A device for radioactivity counting and characterization for a solution. The device includes a container having at least two recesses, a first recess for receiving a vial and a second recess for receiving a radioactivity sensor, a radioactivity sensor having a semiconductor sensor presenting a cone of detection directed to the first recess of the container for receiving a vial, a removable closure element, an armored cover around the container and its upper face, the upper face of the armored cover having an opening for introducing the vial into the container and a plate for supporting the device.Type: GrantFiled: June 18, 2020Date of Patent: March 19, 2024Assignee: UNIVERSITE DE LORRAINEInventors: Guénolé Mathias-Laot, Quentin Thomas
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Patent number: 11832633Abstract: A process for producing a protein isolate from an oilseed meal, and the isolate thus obtained, said isolate comprising proteins and an amount of 4 wt. % or less of phytic acid, said amount of phytic acid being by weight of proteins in said isolate. The process may comprise the following steps: a) providing an oilseed meal; b) mixing the oilseed meal with a first aqueous solvent to form a slurry at a pH ranging from 6 to 7.8, said slurry having a solid phase; c) separating said solid phase from said slurry, d) mixing said separated solid phase with a second aqueous solvent at a pH ranging from 1 to 3.Type: GrantFiled: November 14, 2018Date of Patent: December 5, 2023Assignees: AVRIL, UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Claire Defaix, Romain Kapel, Olivier Galet
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Patent number: 11838530Abstract: A method for concealing data in an image or a video stream inside a compression chain, being implemented by a computer and including a structuring and processing phase, during which at least one image is structured into blocks including coefficients, a phase of converting and quantifying blocks so as to generate converted and quantified coefficients, with entropic coding intended to code the converted and quantified coefficients. The method includes a step of concealing data, during which bits of the data are concealed by modifying converted and quantified coefficients located in a high frequency zone of at least some of the blocks that relate to the luminance component of the video stream and that are intra-coded. This modification is performed after the quantification but before the entropic coding.Type: GrantFiled: February 20, 2020Date of Patent: December 5, 2023Assignees: UNIVERSITE DE LORRAINE, UNIVERSITE DE STRASBOURGInventors: Jean-Marie Moureaux, Amine Chaabouni, Yann Gaudeau
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Publication number: 20230273208Abstract: The use of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) as a marker in a method for identifying a subject suffering from a disease caused by a coronavirus such as COVID-19 at risk of having or developing a severe form and/or a complication or at risk of death, in a method for assessing the severity of a disease caused by a coronavirus such as COVID-19, and in a method for monitoring a subject suffering from a disease caused by a coronavirus such as COVID-19.Type: ApplicationFiled: June 7, 2021Publication date: August 31, 2023Applicants: INOTREM, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE NANCY, UNIVERSITE DE LORRAINE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUMInventors: Jean-Jacques GARAUD, Marc DERIVE, Margarita SALCEDO-MAGGUILLI, Lucie JOLLY, Sébastien GIBOT, David MOULIN, Mihai NETEA, Aline DE NOOIJER
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Patent number: 11712744Abstract: An electrolyte for the electrochemical machining of a ?-?? nickel-based superalloy, includes NaNO3 in a content of between 10% and 30% by weight relative to the total weight of the electrolyte; a complexing agent selected from sulfosalicylic acid at a pH of between 3 and 10 and nitrilotriacetic acid at a pH of between 7 and 14, the complexing agent being present in a content of between 1% and 5% by weight relative to the total weight of the electrolyte; optionally, an anionic surfactant in a content of between 1% and 5% by weight relative to the total weight of the electrolyte; optionally, NaOH in order to obtain the desired pH; and an aqueous solvent.Type: GrantFiled: December 17, 2019Date of Patent: August 1, 2023Assignees: SAFRAN AIRCRAFT ENGINES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LORRAINEInventors: Mariem Msakni Malouche, Janvier Lecomte, Mickael Rancic, Nicolas Stein, Clotilde Boulanger
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Publication number: 20230182342Abstract: A flame retardant treatment of a lignocellulosic material, which includes: optionally steam exploding the lignocellulosic material, impregnating the optionally steam-exploded lignocellulosic material, in or with an aqueous solution, from 0.5% to 10% of phytic acid and from 1% to 30% of urea, based on the total weight of the aqueous solution, optionally drying of the impregnated lignocellulosic material, until the impregnated lignocellulosic material has a moisture content from 5% to 20% by weight, cooking the impregnated and optionally dried lignocellulosic material, the resulting flame-retarded lignocellulosic material including a phosphorous content originating from the phytic acid from 0.1% to 10% by weight.Type: ApplicationFiled: April 8, 2021Publication date: June 15, 2023Applicants: UNIVERSITE DE LORRAINE, INSTITUT MINES TELECOM, UNIVERSITE LIBANAISEInventors: Nicolas BROSSE, Romain KAPEL, Rodolphe SONNIER, Roland EL HAGE, César SEGOVIA, Karina ANTOUN, Maria MOUSSA
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Patent number: 11667873Abstract: The present invention relates to an enzymatic method for removing sulphite. In particular, the present invention relates to a method for converting sulphite present in a composition into thiosulphate, comprising the introduction of 3-mercaptopyruvate sulphurtransferase (3-MST) and a substrate of said 3-mercaptopyruvate sulphurtransferase into said composition. The present invention can be used in particular in the pharmaceutical, cosmetic, food and chemical fields, and any field involving the use of sulphite.Type: GrantFiled: December 22, 2017Date of Patent: June 6, 2023Assignee: UNIVERSITÉ DE LORRAINEInventors: Jean-Christophe Lec, Alexandre Kriznik, François Talfournier, Sandrine Boschi
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Patent number: 11661446Abstract: The present invention relates to a novel method for the affinity purification of proteins of interest in a single step, based on the lectin activity of the CRD (Carbohydrate Recognition Domain) of a galectin or part of said domain retaining the ability to bind ?-galactosidase derivative.Type: GrantFiled: May 11, 2017Date of Patent: May 30, 2023Assignees: UNIVERSITÉ DE LORRAINE, CENTRE HOSPITALIER RÉGIONAL DE NANCYInventors: Alexandre Kriznik, Pascal Saim Reboul, Mélissa Jenner Yelehe-Okouma
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Publication number: 20230147036Abstract: Disclosed is a rotating electrical machine with axial air gap, comprising two rotors, each provided with superconducting axial magnetic flux barrier elements around an axis of rotation and having, between them, axial magnetic flux passage areas, at least one armature, comprising windings and a superconducting field coil surrounding the elements and the armature and capable of inducing an axial magnetic field. Each armature is positioned between two of the rotors. The superconducting elements of the rotors are coaxial with one another and also the flux passage areas. A first annular cryogenic enclosure encloses the field coil and a second cryogenic enclosure encloses the two rotors and the armature or only one rotor, with a third cryogenic enclosure around the other rotor without the armature.Type: ApplicationFiled: March 11, 2021Publication date: May 11, 2023Applicants: UNIVERSITE DE LORRAINE, SAFRANInventors: Alexandre COLLE, Sabrina Siham AYAT, Rémy BIAUJAUD