Patents Assigned to UNIVERSITE GRENOBLE ALPES
  • Patent number: 11179599
    Abstract: A device for acclimatising at altitude comprising a breathing mask defining a confined air space when it is placed on the face of a user. The mask comprising a suction valve to let the surrounding air enter inside the confined space when breathing in; an expiration valve to let air exit with a determined resistance, so as to create an overpressurisation of air in the confined space, when breathing out; and a sensor to establish information about the pressure of the confined space behind. The acclimatisation device in addition comprises a unit for processing the pressure information configured to establish a breathing characteristic of the user and compare it to at least one target value, in view of recommending to them an adjustment of the breathing mode thereof. A method for functioning this device is also provided.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: November 23, 2021
    Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MÉDICALE, UNIVERSITE DE CHAMBERY-UNIVERSITE SAVOIE MONT BLANC
    Inventors: Samuel Verges, Bernard Wuyam, Thomas Rupp
  • Patent number: 11174568
    Abstract: A microfluidic chip comprising at least one dialysis crystallisation cell. The cell includes: a substrate made of PMMA; a first level including a tank defined at least partially by the substrate and by an outer wall of the cell, the tank being in fluid communication with a channel for inlet and a channel for outlet of a solution allowing the crystallisation method to be implemented; and a second level including a dialysis chamber defined at least partially by an inner wall of the cell without contact with the substrate and by a dialysis membrane forming an interface between the tank and the dialysis chamber, the inner wall including at least one one-piece portion in which the periphery of the membrane is kept sealed.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: November 16, 2021
    Assignees: UNIVERSITE GRENOBLE ALPES, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES, LTERNATIVES CENTRE NATIONAL DE LA RECHERCHE, SCIENTIFIQUE RHODIA OPERATIONS, RHODIA LABORATOIRE DU FUTUR, UNIVERSITE DE BORDEAUX
    Inventors: Monika Spano, Jean-Baptiste Salmon, Niels Heinz Junius
  • Publication number: 20210296699
    Abstract: The present invention relates to a solid polymer electrolyte comprising: at least one comb polymer comprising a main chain formed from 1-ethenyl- and/or 1-allyl-2,3,4,5,6-pentafluorobenzene monomers, some of the monomer units of the main chain bearing polymeric side chains based on polymers that are solvents for alkali metal or alkaline-earth metal salts; said chains being grafted in the para position of the pentafluorophenyl groups; and at least one alkali metal or alkaline-earth metal salt, in particular a lithium salt. The invention also relates to a process for preparing a solid polymer electrolyte film and to the use thereof in an electrochemical system, in particular a lithium battery.
    Type: Application
    Filed: February 12, 2021
    Publication date: September 23, 2021
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Lionel PICARD, Thomas CLEMENT, Patrice RANNOU
  • Publication number: 20210282963
    Abstract: The invention relates to a device for cooling an organ locally, that includes an elongate stem including a far end intended to make contact with an organ to be cooled and comprising including a cooling element having a cold finger, a crystal that has a capacity to cool via excitation at a set excitation wavelength, said crystal being positioned adjacent to said cooling element, an optical guide that is able to convey a light signal at said excitation wavelength and that opens onto said crystal, and an illuminating system including at least one light source, which light source is arranged to emit said light signal.
    Type: Application
    Filed: September 12, 2017
    Publication date: September 16, 2021
    Applicants: COMMISSARIAT A L'ENEGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES
    Inventors: Nicolas AUBERT, Claude CHARBROL, Stephan CHABARDES, Luarent DURAFFOURG
  • Publication number: 20210269883
    Abstract: The present disclosure relates to the identification of a biomarker, consisting in a circulating miRNA, suitable for use in the diagnosis and prognosis of high-grade serous ovarian carcinoma (HGSOC), and to diagnostic kits for use in such diagnosis.
    Type: Application
    Filed: July 4, 2019
    Publication date: September 2, 2021
    Applicants: UNIVERSITE DE CAEN NORMANDIE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE REGIONAL FRANCOIS BACLESSE, UNIVERSITE GRENOBLE ALPES
    Inventors: Nicolas VIGNERON, Christophe DENOYELLE, Laurent POULAIN, Jean-Paul ISSARTEL, Bernard LAMBERT, Matthieu MERYET-FIGUIERE, Mégane VERNON, Audrey GUTTIN
  • Patent number: 11104578
    Abstract: The invention relates to an exfoliation method according to which a fluid loaded with particles flows at a first flow rate into a first (2), and then into a second, section of a pipe (1), the first flow rate being suitable for generating shear stresses and cavitation bubbles in the fluid as it passes through the first section (2) of the pipe (1), the second section (3) having a hydraulic diameter suitable for bringing about an implosion of cavitation bubbles as soon as the fluid exits the first section (2) and flows into the second section (3), so that an exfoliation of the particles is brought about under the combined action of the shear stresses and a shock wave generated by the implosion of the cavitation bubbles, the first section (2) having a hydraulic diameter less than 300 ?m.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: August 31, 2021
    Assignee: UNIVERSITE GRENOBLE ALPES
    Inventors: Frédéric Ayela, Damien Colombet
  • Patent number: 11097336
    Abstract: A device and method for producing metal slugs, in which: a movable support has a plurality of cavities separated by partition walls, such that the cavities travel over a path, a feeding means is positioned above a location on said path and is capable of forming a stream of molten metal, flowing under the effect of gravity, such that, during the continuous movement of the movable support, the continuous stream of molten metal from the feeding means is divided or fragmented into slugs formed successively in said cavities, under the effect of said partition walls.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: August 24, 2021
    Assignees: UNIVERSITE GRENOBLE ALPES, INSTITUT POLYTECHNIQUE DE GRENOBLE
    Inventors: Sébastien Gravier, Georges Kapelski
  • Publication number: 20210253760
    Abstract: The present invention relates to a comb polymer comprising a main chain formed from 1-ethenyl- and/or 1-allyl-2,3,4,5,6-pentafluorobenzene monomers and polymeric side chains grafted in the para position of the pentafluorophenyl groups, in which said polymeric side chains are linked to said main chain by an oxygen atom, the molar grafting rate of polymeric side chains being greater than or equal to 50%. It also relates to a method for the preparation of such a comb polymer.
    Type: Application
    Filed: February 12, 2021
    Publication date: August 19, 2021
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Lionel PICARD, Thomas CLEMENT, Patrice RANNOU
  • Publication number: 20210245613
    Abstract: An electrical power converter unit (2) includes: a first connection interface (10) comprising two leads (12, 14) forming a DC input/output interface for connecting a first electrical device to the power converter unit, a three-phase rectifier power converter circuit (16) and a second connection interface (30) for connecting a second electrical device to the power converter unit. The second connection interface includes a switching unit (46) adapted to switch between:—a DC input/output mode, in which first, second and third arms of the power converter circuit (16) are electrically connected together, forming one DC input/output; and—an AC input/output mode, in which the arms are disconnected from each other, forming separate input/outputs for a three-phase AC voltage.
    Type: Application
    Filed: July 25, 2018
    Publication date: August 12, 2021
    Applicants: VOLVO TRUCK CORPORATION, UNIVERSITE GRENOBLE ALPES
    Inventors: Michael MILLET, Christophe MAGNET, David FREY, Julien RICHER, Philippe LE BRUSQ
  • Publication number: 20210219955
    Abstract: The invention relates to a sheath (10) for an endoscopic ultrasound probe, comprising: a first flexible portion (10a) suited to surrounding a catheter (4) of the ultrasound probe, made of a material suited to allowing ultrasounds to pass, having a closed distal end, a second portion (10b) suited to surrounding a handle (2) and a cable (3) for electrically connecting the probe to an ultrasound station, and a fitting (11) arranged between the first and the second portion (10a, 10b), said fitting (11) being suited to being removably attached to the handle (2).
    Type: Application
    Filed: June 3, 2019
    Publication date: July 22, 2021
    Applicant: Universite Grenoble Alpes
    Inventors: Guillaume Custillon, Nicolas Dubois
  • Publication number: 20210212570
    Abstract: The invention relates to a photoacoustic ultrasound probe (100), comprising: a catheter (4), an ultrasound sensor (5) arranged at a distal end (40) of the catheter, at least one optical fibre (50) suited to being connected to a laser source, said optical fibre extending into the catheter up to the distal end (40), said probe being characterised in that the catheter has an inclined distal portion (42) and/or a bevelled distal end (40).
    Type: Application
    Filed: June 3, 2019
    Publication date: July 15, 2021
    Applicant: Universite Grenoble Alpes
    Inventors: Guillaume Custillon, Nicolas Dubois
  • Patent number: 11061325
    Abstract: A photosensitive composition activatable by multiphoton absorption usable for the fabrication of a three-dimensional structure which is biodegradable and/or biocompatible and/or bioresorbable. This structure is usable as a matrix for cell culture. The photosensitive composition comprises: gelatin, collagen, a water-soluble photoinitiator, able to be excited by several photons and capable of generating singlet oxygen, optionally a cell adhesion promoter, and water. A process for preparing the photosensitive composition, a process for preparing a three-dimensional structure from the photosensitive composition, the three-dimensional structure obtained by this preparation process and a matrix for cell culture comprising this structure.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: July 13, 2021
    Assignee: UNIVERSITE GRENOBLE ALPES
    Inventors: Olivier Stephan, Laetitia Gredy
  • Publication number: 20210196172
    Abstract: A method for determining a membership function, the membership functions allowing a stress level of a user to be determined on the basis of a physiological parameter measured on the user, the membership function varying, depending on the physiological parameter, between: a first value, representative of a rest state; and a second value, representative of a stressed state; the membership function taking into account a distribution function, which is defined beforehand, the distribution function being a continuous and monotonic function, the distribution function being applied to a normalized parameter established on the basis of a measured physiological parameter, the method comprising determining a normalization function, and optionally a standardization function, the normalization function and the optional standardization function being determined on the basis of physiological parameters measured on a plurality of test individuals, in various calibration periods.
    Type: Application
    Filed: December 23, 2020
    Publication date: July 1, 2021
    Applicants: Commissariat à l'Energie Atomique et aux Energies Alternatives, UNIVERSITE GRENOBLE ALPES
    Inventors: Gaël VILA, Christelle GODIN
  • Patent number: 11045539
    Abstract: The present disclosure is related to a live-attenuated strain of Pseudomonas for its use as a vaccine, and for use in a method for preventive immunizing and for treating Pseudomonas infection, in particular in patients suffering from cystic fibrosis. Preferably, the live-attenuated strain of Pseudomonas is furthermore treated to become ‘killed but metabolically active’.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: June 29, 2021
    Assignees: Universite Grenoble Alpes, Centre Hospitalier Universitaire Grenoble Alpes, Establissement Francais Du Sang
    Inventors: Audrey Le Gouellec, Bertrand Toussaint, Jean-Luc Lenormand, David Laurin, Elodie Meynet
  • Patent number: 11040191
    Abstract: The invention concerns a method of forming a medical device, the method comprising: forming a graphene film (100) over a substrate (204); depositing, by gas phase deposition, a polymer material covering a surface of the graphene film (100); and removing the substrate (204) from the graphene film (100), wherein the polymer material forms a support (102) for the graphene film (100).
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: June 22, 2021
    Assignees: Centre National de la Recherche Scientifique, UNIVERSITE GRENOBLE ALPES
    Inventors: Dipankar Kalita, Vincent Bouchiat, Laetitia Marty, Nedjma Bendiab
  • Publication number: 20210147899
    Abstract: Method for determining the sensitivity of a bacterial strain of interest to a viral strain of bacteriophages, the method comprising: a) preparing a sample, this comprising bringing bacteria, belonging to the bacterial strain of interest, into contact with bacteriophages, each bacteriophage belonging to the same viral strain, the bacteria being either in a liquid medium, or in an agar medium; b) placing the sample between a light source and an image sensor, the light source emitting a light wave in an emission spectral band comprised between 500 nm and 600 nm; c) illuminating the sample using the light source and acquiring at least one image of the sample, with the image sensor, in the emission spectral band, no image-forming optic being placed between the sample and the image sensor; d) on the basis of the acquired images, determining a sensitivity of the bacterial strain of interest to the viral strain.
    Type: Application
    Filed: November 13, 2020
    Publication date: May 20, 2021
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPES
    Inventors: Prisca PERLEMOINE, Thomas BORDY, Pierre MARCOUX, Emmanuel PICARD, Rémi TOUTAIN, Marc ZELSMANN, Alexis MAIRE
  • Patent number: 11005261
    Abstract: A control method allows the control of an installation for transmitting electricity comprising a DC transmission network including a group of electricity transmission lines that are linked to one another. The method allows the opening of at least one N-1 safety system, for each safety system being opened, the contribution to the flow of current through the group of transmission lines, originating from the converter station associated with the safety system that is opened, is removed. Furthermore, the method also allows a search for the short-circuit fault in order to identify the faulty transmission line, and an operation, implemented after identification of the faulty transmission line by the search step, of isolating the faulty transmission line by opening the line circuit breakers of the faulty transmission line.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: May 11, 2021
    Assignees: Supergrid Institute, Universite Grenoble Alpes
    Inventors: Dieynaba Loume, Alberto Bertinato, Bertrand Raison
  • Publication number: 20210130385
    Abstract: The present invention relates to a compound of formula (I): (I) as defined in the description. The present invention also relates to a method for extracting biological membrane-associated membrane proteins, comprising a step of bringing an aqueous solution of biological membrane-associated membrane proteins into contact with at least one compound of the invention. The present invention also relates to a method for stabilizing membrane proteins in solution in an aqueous solution, comprising a step (i) consisting in bringing an aqueous solution of a membrane protein in solution into contact with at least one compound of the invention.
    Type: Application
    Filed: December 27, 2017
    Publication date: May 6, 2021
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1, UNIVERSITE GRENOBLE ALPES
    Inventors: Pierre FALSON, Julien DAUVERGNE, Ahcène BOUMENDJEL, Marine PEUCHMAUR, Kim Anh NGUYEN, Sandrine MAGNARD
  • Patent number: 10978234
    Abstract: A magnetic stack includes a first element including a ferromagnetic layer; a second element including a metal layer able to confer on the assembly formed by the first and the second elements a magnetic anisotropy perpendicular to the plane of the layers. The first element further includes a refractory metal material, the second element being arranged on the first element.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: April 13, 2021
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITÉ GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Jyotirmoy Chatterjee, Paulo Veloso Coelho, Bernard Dieny, Ricardo Sousa, Lucian Prejbeanu
  • Patent number: 10960191
    Abstract: The device, that can be implanted in the intestinal cavity, comprises a reactor comprising a semi-permeable or porous membrane or coating linked to a element for attachment to an intestinal or gastric wall. The reactor can be in the form of a ribbon, a structure having more than two faces or an open structure delimiting a lumen, comprising, or formed from, a semi-permeable or porous membrane. The reactor can also delimit, at least partially with the semi-permeable or porous membrane of same, a closed inner space. The reactor can comprise or carry enzymes or micro-organisms, in particular bacteria or yeast. The reactor is used for generating a chemical reaction with one or more molecules present in the intestine, or for producing one or more biologically active molecules. It can, in particular, be used for consuming sugars, disaccharides and simple sugars or producing essential amino acids or other molecules having a positive effect on the health.
    Type: Grant
    Filed: April 4, 2016
    Date of Patent: March 30, 2021
    Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE
    Inventors: Philippe Cinquin, Dominique Schneider, Max Maurin, Donald Martin, Sarra El Ichi, Abdelkader Zebda, Jean-Pierre Alcaraz, Fabian Reche, Patrick Tuvignon, Jacques Thelu, Audrey Le Gouellec, Bertrand Toussaint