Abstract: The invention relates to peptides which can become fixed to the engrailed transcription factor and which can modulate the activity thereof.

Abstract: The invention relates to peptides which can become fixed to the engrailed transcription factor and which can modulate the activity thereof.

Abstract: The present invention relates to derivatives of 1-hydroxymethylene-1,1-bisphosphonic acid, the pharmaceutical compositions comprising them, and their application in therapeutics, particularly for the treatment of cancerous tumors. It is also directed to a methods of preparation of such derivatives.

Abstract: A method for analyzing a diffusing sample comprises steps of: a) illuminating the sample with temporally coherent and wavelength-modulated incident light beam; b) producing a succession of interference signals with the diffuse light; c) combining each interference signal with a reference signal (Ref(t,?0)) generating a time port; d) extracting the continuous component of each signal characteristic of the predetermined delay (?0) derived form c); applying a nonlinear function on each of the continuous components of the signals characterizing the predetermined delay (?0); and f) averaging each of the images, with the non-linear function, of the continuous components of the signals characterizing the predetermined delay (?0). The invention is useful for observing organs of the human body.

Abstract: The invention proposes a novel technique for implementing high performance atomic lithography, and in particular high resolution lithography. The technique makes use of Stern-Gerlach type atomic interferometry enabling disturbances to be implemented in the atomic phase of the beam. Such interaction then directly modulates the intensity of the associated wave in the plane extending transversely to the beam of atoms, and does so in controllable manner. The installation of the invention for nanolithography by atomic interferometry comprises a Stern-Gerlach type interferometer comprising, as its phase object, four-pole magnetic induction having a transverse gradient created by four parallel bars carrying alternating direct currents, bracketed between two separator plates, preceded and followed respectively by a spin polarizer and by an analyzer operating by laser pumping.

Abstract: The present invention relates to derivatives of 1-hydroxymethylene-1,1-bisphosphonic acid, the pharmaceutical compositions comprising them, and their application in therapeutics, particularly for the treatment of cancerous tumors. It is also directed to a methods of preparation of such derivatives.