Patents Assigned to UNIVERSITY-INDUSTRY FOUNDATION (UIF)
  • Publication number: 20240066107
    Abstract: The present invention relates to a pharmaceutical composition for treating gout, and a gout treatment kit. According to an embodiment of the present invention, a pharmaceutical composition for treating gout comprising a probe containing at least one or more peptides specifically coupled to a monosodium urate MSU crystals; and a first enzyme which is coupled to the probe, and reacts with the target MSU crystal coupled to the probe or urea of surrounding joint fluid to remove the target MSU crystal is provided.
    Type: Application
    Filed: August 18, 2020
    Publication date: February 29, 2024
    Applicant: UNIVERSITY-INDUSTRY FOUNDATION(UIF), YONSEI UNIVERSITY
    Inventor: Jae-Chul PYUN
  • Patent number: 11696709
    Abstract: The present invention relates to a liquid information sensor comprises at least more than one electrode set including a first electrode, and a second electrode which is disposed spaced apart from the first electrode and to which an alternating current signal is applied between the first electrode and the second electrode; and a ferroelectric layer including a first side in contact with the first electrode and the second electrode and a second side facing the first side and defining a receiving area for receiving the target liquid, and generating sound waves by physical vibration when the AC signal is applied.
    Type: Grant
    Filed: December 4, 2019
    Date of Patent: July 11, 2023
    Assignee: UNIVERSITY-INDUSTRY FOUNDATION (UIF), YONSEI UNIVERSITY
    Inventors: Cheolmin Park, Jong Sung Kim, Eui Hyuk Kim, Chanho Park
  • Patent number: 11695097
    Abstract: A light-emitting device according to the present invention comprises, an electrode unit including a first electrode and a second electrode spaced apart from each other, with electrical signals having different polarity applying the first and second electrode, respectively; a first stimulation unit disposed on one surface of the electrode unit and having a first stimulation reaction layer expressing variable luminance according to a first stimulation; and a second stimulation unit disposed on the other surface facing the one surface of the electrode unit, and having a second stimulation reaction layer expressing a variable luminance according to a second stimulation different from the first stimulation.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: July 4, 2023
    Assignee: UNIVERSITY-INDUSTRY FOUNDATION (UIF), YONSEI UNIVERSITY
    Inventors: Cheolmin Park, Woo Kyoung Jin, Eui Hyuk Kim
  • Patent number: 11624745
    Abstract: A method of screening an antibody comprises preparing a serum having a target antibody and a non-target antibody; providing the serum with a first antigen that specifically binds the target antibody to obtain a first mixture; selectively obtaining the first conjugate by separating the first conjugate from the non-target antibody in the first mixture; dissociating the first conjugate, and a redundant non-target antibody adsorbed to the first conjugate into the first antigen, the target antibody and the redundant non-target antibody; removing the first antigen to obtain a second mixture of the target antibody and the redundant non-target antibody; providing the second mixture with a second antigen to form a second conjugate, so that third mixture including the target antibody and the second conjugate may be obtained; and selectively obtaining a target antibody by separating the second conjugate from the target antibody in the third mixture.
    Type: Grant
    Filed: March 1, 2020
    Date of Patent: April 11, 2023
    Assignee: UNIVERSITY-INDUSTRY FOUNDATION (UIF), YONSEI UNIVERSITY
    Inventor: Jae-Chul Pyun
  • Publication number: 20220405563
    Abstract: A method for predicting a molecular structure includes: preparing a learning data set including first learning data including an eigenvector value and a quantum mechanics calculation value for a monoatomic and molecular structural model, a bulk structural model, a slab structural model, and a nanoparticle structural model of a material including a plurality of elements; learning an artificial neural network using the learning data set to obtain a potential value; and predicting a molecular structure of another material by using the potential value.
    Type: Application
    Filed: June 1, 2022
    Publication date: December 22, 2022
    Applicants: HYUNDAI MOTOR COMPANY, KIA CORPORATION, YONSEI UNIVERSITY, UNIVERSITY - INDUSTRY FOUNDATION (UIF)
    Inventors: Seunghyo Noh, Kyungju Nam, Byungchan Han
  • Patent number: 11454835
    Abstract: Disclosed are a light emission device including a magnetoactive element, a method of fabricating the same, and an electronic device including the light emission device. The disclosed light emission device may include a light emission layer; a first electrode and a second electrode spaced apart from each other on a first surface side of the light emission layer; and a magnetoactive fluid layer disposed on a second surface side of the light emission layer and having a plurality of nanostructures of which arrangement and distribution is configured to change according to application of a magnetic field. The light emitting properties of the light emission layer may be changed according to the arrangement and distribution of a plurality of nanostructures in the magnetoactive fluid layer. The plurality of nanostructures may include conductive nanowire and magnetic nanoparticle provided on the surfaces of the conductive nanowire.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: September 27, 2022
    Assignee: UNIVERSITY-INDUSTRY FOUNDATION (UIF), YONSEI UNIVERSITY
    Inventors: Cheolmin Park, Soyeon Baek, Seung Won Lee
  • Patent number: 11192330
    Abstract: Provided are a porous structure and a method of fabricating the same. The porous structure may include an aluminum oxide containing at least one of fluorine and phenyl group. For example, the porous structure may be formed from alumina which contains fluorine or phenyl group. The method of fabricating the porous structure may include preparing an aluminum precursor including at least one of fluorine and phenyl group; providing a precursor solution by mixing the precursor with a solvent; and forming the porous structure having 3-dimensional network structure including the aluminum oxide containing the at least one of fluorine and phenyl group from the precursor solution through gelation.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: December 7, 2021
    Assignee: UNIVERSITY-INDUSTRY FOUNDATION (UIF), YONSEI UNIVERSITY
    Inventors: Hyung Ho Park, Hee Yoon Chung, Hae Noo Ree Jung, Tae Won Lee
  • Patent number: 11075065
    Abstract: The present disclosure relates to a sample plate for laser desorption/ionization mass spectrometry comprising a substrate including a surface corrosion layer, and the surface corrosion layer constitutes at least a portion of the photoreaction catalyst layer, and a photocatalytic catalyst layer including a metal oxide formed on the substrate, wherein a sample to be analyzed is disposed on the photocatalytic catalyst layer.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: July 27, 2021
    Assignee: UNIVERSITY-INDUSTRY FOUNDATION (UIF), YONSEI UNIVERSITY
    Inventor: Jae-Chul Pyun
  • Publication number: 20210202826
    Abstract: The present invention relates to a piezoelectric structure, a method of fabricating the same, and a pressure sensor using the same. A piezoelectric structure comprises perovskite structure layers including a material having an ABO3 perovskite structure and an interlayer including a metal oxide A*O interposed between the perovskite structure layers. A or A* is one of an alkaline earth metal element, an alkali metal element, a lanthanum group element, and a post-transition metal element, B is a transition metal element, and O is an oxygen element.
    Type: Application
    Filed: November 18, 2020
    Publication date: July 1, 2021
    Applicant: UNIVERSITY-INDUSTRY FOUNDATION(UIF), YONSEI UNIVERSITY
    Inventors: Hyung Ho PARK, Kyung Mun KANG, Yue WANG, Min Jae KIM, Chabungbam Akendra SINGH, Chan LEE
  • Patent number: 10989779
    Abstract: An under-sampling apparatus for MR image reconstruction by using machine learning and a method thereof, an MR image reconstruction device by using machine learning and a method thereof, and a recoding medium thereof are disclosed. The disclosed under-smapling apparatus includes: a setting portion that sets a region corresponding to a center of the k-space image as a first region and remaining regions as a second region; and an under-sampling portion that full-samples the first region and under-samples the second region, wherein in the under-sampling performed in the second region, lines are selected at regular intervals and then only the selected line is full-sampled. According to the under-sampling apparatus, a high-resolution MR image can be acquired while reducing imaing time.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: April 27, 2021
    Assignee: YONSEI UNIVERSITY, UNIVERSITY - INDUSTRY FOUNDATION (UIF)
    Inventors: Chang Min Hyun, Jin Keun Seo, Hwa Pyung Kim, Sung Min Lee, Sung Chul Lee
  • Publication number: 20210088815
    Abstract: Disclosed are a light emission device including a magnetoactive element, a method of fabricating the same, and an electronic device including the light emission device. The disclosed light emission device may include a light emission layer; a first electrode and a second electrode spaced apart from each other on a first surface side of the light emission layer; and a magnetoactive fluid layer disposed on a second surface side of the light emission layer and having a plurality of nanostructures of which arrangement and distribution is configured to change according to application of a magnetic field. The light emitting properties of the light emission layer may be changed according to the arrangement and distribution of a plurality of nanostructures in the magnetoactive fluid layer. The plurality of nanostructures may include conductive nanowire and magnetic nanoparticle provided on the surfaces of the conductive nanowire.
    Type: Application
    Filed: September 24, 2020
    Publication date: March 25, 2021
    Applicant: UNIVERSITY-INDUSTRY FOUNDATION(UIF), YONSEI UNIVERSITY
    Inventors: Cheolmin PARK, Soyeon BAEK, Seung Won LEE
  • Patent number: 10929284
    Abstract: A memory system including a memory subsystem and a memory controller is provided. The memory subsystem includes a plurality of first memory modules implemented by a phase-change memory and a second memory module implemented by a memory whose write speed is faster than that of the phase-change memory. The memory controller generates a non-blocking code from a plurality of sub-data into which original data are divided, writes the non-blocking code to the second memory module, writes the plurality of sub-data to the plurality of first memory modules, respectively, and reconstructs the original data from some sub-data of the plurality of sub-data which are read from some of the plurality of first memory modules and the non-blocking code read from the second memory under a predetermined condition at a read request.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: February 23, 2021
    Assignees: MemRay Corporation, Yonsei University, University-Industry Foundation (UIF)
    Inventors: Myoungsoo Jung, Gyuyoung Park
  • Patent number: 10929059
    Abstract: A resistance switching memory-based accelerator configured to be connected to a host including a CPU and a system memory is provided. A resistance switching memory module includes a memory cell array including a plurality of resistance switching memory cells, and stores a kernel offloaded from the host. An accelerator core includes a plurality of processing elements, and the kernel is executed by a target processing element among the plurality of processing elements. An MCU manages a memory request generated in accordance with execution of the kernel by the target processing element. A memory controller is connected to the resistance switching memory module, and allows data according to the memory request to move between the resistance switching memory module and the target processing element, in accordance with the memory request transferred from the MCU. A network integrates the accelerator core, the plurality of processing elements, and the memory controller.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: February 23, 2021
    Assignees: MemRay Corporation, Yonsei University, University-Industry Foundation (UIF)
    Inventors: Myoungsoo Jung, Gyuyoung Park, Jie Zhang
  • Patent number: 10904539
    Abstract: Disclosed are methods, apparatuses, and systems for encoding and decoding an image. The present invention provides an intra prediction unit receives an input image, removes high frequency ingredients by low pass filtering an encoded luma pixel value in the input image during intra prediction, and generates a prediction block by predicting a chroma pixel value by using a low pass filter (LPF) LM chroma mode for applying an LM chroma mode, which is an extended chroma mode technique for generating a prediction block by predicting the chroma pixel value by applying a correlation between color planes to the luma pixel value having removed therefrom the high frequency ingredients.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: January 26, 2021
    Assignee: UNIVERSITY-INDUSTRY FOUNDATION(UIF), YONSEI UNIVERSITY
    Inventors: Yoon Sik Choe, Jang Won Choi
  • Patent number: 10886451
    Abstract: Provided are a thermoelectric material, a method of fabricating the same, and a thermoelectric device. The thermoelectric material includes a first material layer including a chalcogen element; and a second material layer including a reaction compound between the chalcogen element and a metal element, wherein the thermoelectric material has a structure in which the first material layer is inserted in the second material layer.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: January 5, 2021
    Assignee: UNIVERSITY-INDUSTRY FOUNDATION (UIF), YONSEI UNIVERSITY
    Inventors: Mann Ho Cho, Hye Jin Choi, Ji Min Chae, Han Bum Park
  • Publication number: 20200378960
    Abstract: The present invention relates to a bio-electrode for current measurement including silicon carbide (SiC) doped at least partially with nitrogen (N). The bio-electrode for current measurement according to an embodiment of the present invention is a bio-electrode for a current measurement which is contact with an object to be analyzed, which generates a current signal by an electrochemical reaction, and includes silicon carbide (SiC) doped at least partially with nitrogen (N). The electrode may be used in a high-sensitive bio-quantification kit, a high-sensitive bio-quantification device, and an immunoassay device.
    Type: Application
    Filed: March 29, 2020
    Publication date: December 3, 2020
    Applicant: UNIVERSITY-INDUSTRY FOUNDATION(UIF), YONSEI UNIVERSITY
    Inventor: Jae-Chul PYUN
  • Publication number: 20200371092
    Abstract: A method of screening an antibody comprises preparing a serum having a target antibody and a non-target antibody; providing the serum with a first antigen that specifically binds the target antibody to obtain a first mixture; selectively obtaining the first conjugate by separating the first conjugate from the non-target antibody in the first mixture; dissociating the first conjugate, and a redundant non-target antibody adsorbed to the first conjugate into the first antigen, the target antibody and the redundant non-target antibody; removing the first antigen to obtain a second mixture of the target antibody and the redundant non-target antibody; providing the second mixture with a second antigen to form a second conjugate, so that third mixture including the target antibody and the second conjugate may be obtained; and selectively obtaining a target antibody by separating the second conjugate from the target antibody in the third mixture.
    Type: Application
    Filed: March 1, 2020
    Publication date: November 26, 2020
    Applicant: UNIVERSITY-INDUSTRY FOUNDATION(UIF), YONSEI UNIVERSITY
    Inventor: Jae-Chul PYUN
  • Publication number: 20200370104
    Abstract: The present invention provides a method for detection of a mutation in a nucleotide sequence, the method comprising the steps of: obtaining a plurality of target genes for one subject sample by using a gene panel including probes for the plurality of target genes; collecting multiple replicates of nucleotide sequences including nucleotide sequences being identical or non-identical with each of the plurality of target genes by sequencing each of the plurality of target genes in multiple rounds through next generation sequencing (NGS); matching the multiple replicates of nucleotide sequences with reference nucleotide sequences; determining nucleotide sequences unmatched with the reference nucleotide sequences for the plurality of target genes among the multiple replicates of nucleotide sequences; and determining candidates of nucleotide sequence mutations for the plurality of target genes in the subject sample, based on a probability of mutation for a discordant gene locus with the unmatched nucleotide sequence
    Type: Application
    Filed: August 6, 2018
    Publication date: November 26, 2020
    Applicant: Yonsei University, University - Industry Foundation (UIF)
    Inventors: Sangwoo Kim, Junho Kim
  • Patent number: 10831376
    Abstract: A flash-based accelerator configured to be connected to a host including a CPU and a system memory is provided. A plurality of processors execute a plurality of kernels offloaded from the host. A memory system includes a first memory that is used to map a data section of each kernel to the flash memory. A supervisor processor maps a region of the first memory pointed by a data section of a first kernel to a region of the flash memory to allow first data to move between the region of the first memory and the region of the flash memory, based on a first message which is transferred in accordance with execution of the first kernel by a first processor among the plurality of processors. A network integrates the flash backbone, the memory system, the plurality of processors, and the supervisor processor.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: November 10, 2020
    Assignees: MemRay Corporation, Yonsei University, University- Industry Foundation (UIF)
    Inventors: Myoungsoo Jung, Jie Zhang
  • Patent number: 10824341
    Abstract: In a flash-based accelerator, a flash-based non-volatile memory stores data in pages, and a buffer subsystem stores data in words or bytes. An accelerator controller manages data movement between the flash-based non-volatile memory and the buffer subsystem. A plurality of processors processes data stored in the buffer subsystem. A network integrates the flash-based non-volatile memory, the buffer subsystem, the accelerator controller, and the plurality of processors.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: November 3, 2020
    Assignees: MemRay Corporation, Yonsei University, University-Industry Foundation (UIF)
    Inventors: Myoungsoo Jung, Jie Zhang