Patents Assigned to University of Central Florida
  • Publication number: 20240288690
    Abstract: Here discloses an optical display system and an electronics device. The optical display system comprises: image-generating display; controllable polarization rotator module, which receives light from the image-generating display and outputs the light into polarized light with a first polarization and/or a second polarization under control; a first reflective lens, which reflects the polarized light with a first polarization to a pupil of an observer; and a second reflective lens, which reflects the polarized light with a second polarization to the pupil, wherein the first reflective lens and the second reflective lens have different optical powers to produce image planes at different depths.
    Type: Application
    Filed: June 21, 2022
    Publication date: August 29, 2024
    Applicants: University of Central Florida Research Foundation, Inc., Goertek Inc.
    Inventors: YANNANQI LI, Jianghao Xiong, Qian Yang, Kun Li, Shin-Tson Wu
  • Patent number: 12070474
    Abstract: Disclosed herein are novel compositions and methods for stimulation of and the production or expansion of natural killer (NK) cells. Numbers of NK cells can be increased following contact with exosomes modified with one or more stimulatory peptides. Methods and compositions for the production of exosomes, wherein the exosomes comprises stimulatory peptides are also described. Also described are methods of treating cancer using the disclosed NK-stimulating exosomes or NK cells stimulated by the disclosed methods.
    Type: Grant
    Filed: January 26, 2022
    Date of Patent: August 27, 2024
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Alicja J. Copik, Jeremiah L. Oyer, Robert Y. Igarashi, Deborah Altomare
  • Patent number: 12071436
    Abstract: The present disclosure provides compounds of Formula (I?), Formula (II), and Formula (III). The compounds described herein may useful in treating and/or preventing protozoan infections in a subject in need thereof, treating and/or preventing trypanosomal infections (e.g., Trypanosoma cruzi (T. cruzi) or Trypanosoma brucei infections) and/or plasmodial infections in a subject in need thereof, treating and/or preventing diseases in a subject in need thereof (e.g., Chagas disease, malaria, and/or sleeping sickness), and may be useful in treating and/or preventing infectious diseases in a subject in need thereof. Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including a compound described herein.
    Type: Grant
    Filed: November 22, 2021
    Date of Patent: August 27, 2024
    Assignees: University of Central Florida Research Foundation, Inc., The Regents of the University of California, Memorial Sloan-Kettering Cancer Center, The Broad Institute, Inc.
    Inventors: Derek Shieh Tan, Corinne N. Foley, Gustavo Moura-Letts, James McKerrow, Sivaraman Dandapani, Rahul Edwankar, Alyssa Verano, Debopam Chakrabarti, Bracken Roberts
  • Patent number: 12070031
    Abstract: Compositions and methods for systemic delivery of at least one cargo in a vascular plant. Compositions may include at least one cargo delivery particle, having a core and a shell; and at least one cargo disposed on the shell. The core may include at least one micronutrient. The shell may include a coating material. The at least one cargo delivery particle may have a size of less than about 10 nanometers. Methods may include administering an effective amount of the compositions to a plant.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: August 27, 2024
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Tyler Maxwell, Swadeshmukul Santra, Parthiban Rajasekaran
  • Patent number: 12071851
    Abstract: The system extracts water from lunar regolith and includes a regolith intake having a digging bucket that collects lunar regolith soil and a gravel separator that separates and discharges gravel and passes a mixture of ice-regolith powder having ice grains that are about 10-100 microns along the conveyor. A pneumatic separator receives the ice-regolith powder and pneumatically splits the ice-regolith powder into streams of different sized lithic fragments and ice particles per the ratio of inertial force and aerodynamic drag force of the lithic fragments and ice particles. Each split stream may include a magnetic separator that separates further the magnetic and paramagnetic lithic fragments from ice particles to discharge up to 80 percent of lithic fragments to slag.
    Type: Grant
    Filed: May 17, 2023
    Date of Patent: August 27, 2024
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventor: Philip Metzger
  • Publication number: 20240272434
    Abstract: An optical imaging system and an imaging device are disclosed. The optical imaging system includes: a display assembly, which outputs lights of an image; a lens assembly, which enlarges the image; a polarization converter, wherein the polarization converter is a frequency-dependent polarization converter, which can convert the lights of a first frequency to a first polarization and convert the lights of a second frequency to a second polarization; and an aberration-correcting optical assembly, which is a polarization-dependent planar optics assembly.
    Type: Application
    Filed: February 8, 2024
    Publication date: August 15, 2024
    Applicants: University of Central Florida Research Foundation, Inc., Goertek Inc.
    Inventors: Zhenyi Luo, Yannanqi Li, Shin-Tson Wu, Yi Rao
  • Patent number: 12061165
    Abstract: One type of plasmonic organic electrochemical transistor (POECT) includes a channel comprising an organic semiconductor, a gate electrode comprising at least one of: an ensemble of nanoparticles and an array of nanostructures, wherein each of the at least one of: an ensemble of nanoparticles and an array of nanostructures comprises localized plasmonic material, an analyte formed at least one of: (a) over the at least one of: the ensemble of nanoparticles and the array of nanostructures and (b) around the at least one of: the ensemble of nanoparticles and the array of nanostructures, wherein an electrolyte is configured to be formed at least one of: between the channel and the gate electrode and over the channel and the gate electrode, a source electrode electrically connected to a first end of the channel; and a drain electrode electrically connected to a second end of the channel which is opposite the first end.
    Type: Grant
    Filed: November 22, 2021
    Date of Patent: August 13, 2024
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Jayan Thomas, Jinxin Li, Foram Madiyar
  • Publication number: 20240263362
    Abstract: A method for manufacturing a color-changing product using an electrical connectorization system including an ultrasonic welder includes providing a fabric to the electrical connectorization system where the fabric includes a plurality of color-changing fibers, providing a connection bus to the electrical connectorization system, and operating the electrical connectorization system to move the fabric and the connection bus into engagement with the ultrasonic welder to generate one or more welds between the connection bus and at least a subset of the plurality of color-changing fibers as the fabric and the connection bus pass the ultrasonic welder.
    Type: Application
    Filed: April 2, 2024
    Publication date: August 8, 2024
    Applicant: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Ayman Abouraddy, Joshua Kaufman, Morgan Monroe, Felix Tan
  • Patent number: 12055724
    Abstract: An optical display system and an electronic device are disclosed. The optical display system comprises: an image generating unit, which generates an image light output, wherein the image light output has a narrow angular luminance distribution; and an optical lens system, which is placed in front of the image generating unit and guides the image light output to an eye of a viewer, wherein the image generating unit includes: an image generating component, which generates a polarized light output; a polarization-dependent light deflection component, disposed to accept the polarized light output from the image-generating component and increase the amount of the polarized light output that can enter an exit pupil of the optical lens system, and the polarized light output deflected by the polarization-dependent light deflection component has the narrow angular luminance distribution.
    Type: Grant
    Filed: December 20, 2021
    Date of Patent: August 6, 2024
    Assignees: University of Central Florida Research Foundation, Inc., Goertek Inc.
    Inventors: Tao Zhan, En-Lin Hsiang, Jianghao Xiong, Shin-Tson Wu, Kun Li
  • Publication number: 20240257361
    Abstract: A method for motion estimation in CT systems is provided. The method includes dividing projection data, obtained by scanning a heart using the CT system, into a plurality of partial-angle-reconstruction (PAR) bins, reconstructing a plurality of PAR volumes from the PAR-binned projection data, obtaining, based on the plurality of reconstructed PAR volumes, a number of short-scan volumes, determining, based on the obtained number of short-scan volumes, a plurality of nodes throughout the heart, estimating, for each of the determined plurality of nodes, a plurality of model parameters of a motion model, and generating, based on the plurality of model parameters estimated for each of the plurality of nodes, parameters of a global motion model at each voxel of a volume of the heart. The method also includes reconstructing, based on the generated motion parameters of the global motion model at each voxel of the volume of the heart, a motion-compensated short-scan volume.
    Type: Application
    Filed: January 26, 2024
    Publication date: August 1, 2024
    Applicants: iTOMOGRAPHY CORPORATION, THE UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, Inc., CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Seongjin YOON, Alexander KATSEVICH, Michael FRENKEL, Qiulin TANG, Liang CAl, Jian ZHOU, Zhou YU
  • Publication number: 20240255830
    Abstract: A system can include a beamsplitter configured to be in optical communication with an optical input source configured to generate one or more input optical signals. The beamsplitter can be configured to split the one or more input optical signals into one or more seed optical signals configured to propagate along a first optical path, and one or more pump optical signals configured to propagate along a second optical path. The system can include a frequency divider in optical communication with the beamsplitter to receive the one or more seed optical signals. The frequency divider can be configured to divide optical frequencies of the one or more seed optical signals in half to provide one or more subharmonic seed optical signals. The system can include a beam combiner in optical communication with the frequency divider to receive the one or more subharmonic seed optical signals, and with the beamsplitter to receive the one or more pump optical signals.
    Type: Application
    Filed: January 12, 2024
    Publication date: August 1, 2024
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventor: Konstantin Vodopyanov
  • Publication number: 20240256770
    Abstract: A prediction system may train a neural network model to analyze data to predict sentiments associated with the data and a measure of incompleteness of the data. The prediction system may obtain communication data regarding a communication session between a first device and a second device. The communication data is obtained via a network. The prediction system may provide the communication data as an input to the trained neural network model. The prediction system may determine, using the trained neural network model, a first set of sentiments associated with the first device and a second set of sentiments associated with the second device. The prediction system may determine, using the trained neural network model, a measure of incompleteness of the communication data based on the first set of sentiments and the second set of sentiments. The prediction system may perform an action based on the measure of incompleteness.
    Type: Application
    Filed: January 26, 2024
    Publication date: August 1, 2024
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventors: Varadraj Gurupur, Muhammed Shelleh, Roger Azevedo
  • Patent number: 12049663
    Abstract: Methods of accurately determining DNA barcodes using a cylindrical nanopore system. The methods include steps of leveraging the average velocity of a double-stranded DNA segment passing through a single cylindrical nanopore that is measured through repeated scanning to accurately determine protein tag locations on the double-stranded DNA segment. As such, the methods provide for the accurate calculation of a barcode for the double-stranded DNA segment based on protein tag locations without underestimation or overestimate issues. The underlying concept and the methods are equally applicable to other multi-nanopore systems which use the dwell time and time of flight velocities to measure the barcodes.
    Type: Grant
    Filed: February 1, 2022
    Date of Patent: July 30, 2024
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Aniket Bhattacharya, Swarnadeep Seth
  • Patent number: 12050320
    Abstract: A display device and an electronic apparatus are disclosed. The display device comprises: an image-display component, which generates an image light output, wherein at least one pixel light of the image light output has light polarization components of at least two polarization states or has a polarization light component of a polarization state and a non-polarization light component; and a polarization dependent image offset component, which receives the image light output coming from the image display component and deflects the polarization light components based on the polarization states to separate each of the at least one pixel light into at least two pixel lights, or deflects the polarization light component from the non-polarization light component to separate each of the at least one pixel light into at least two pixel lights.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: July 30, 2024
    Assignees: University of Central Florida Research Foundation, Inc., Goertek Inc.
    Inventors: Tao Zhan, Jianghao Xiong, Guanjun Tan, Yun-Han Lee, Shin-Tson Wu, Sheng Liu, Jilin Yang
  • Patent number: 12044950
    Abstract: A method is for operating a phased array. The method includes operating circuity coupled between first and second electrically conductive contacts to apply a voltage signal between the first and second electrically conductive contacts, change the voltage signal to selectively set phase change between IR radiation emitted from adjacent elliptical holes to emit the IR radiation at an angle from normal, and change the voltage signal to selectively set a frequency range of the IR radiation.
    Type: Grant
    Filed: December 7, 2023
    Date of Patent: July 23, 2024
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Michael N. Leuenberger, Muhammad Waqas Shabbir
  • Patent number: 12037710
    Abstract: A method of manufacturing a color-changing fiber includes loading a polymeric material and a thermochromic pigment material into a fiber fabrication machine that comprises an extruder and a spinneret, operating the extruder to provide a molten mixture of the polymeric material and the thermochromic pigment material, providing a volume of the molten mixture to the spinneret, and operating the spinneret to coat an electrically conductive core with the molten mixture to form a coating layer around the electrically conductive core to produce the color-changing fiber. The polymeric material and the thermochromic pigment material are provided as (a) a first raw material comprising the polymeric material and a second raw material comprising the thermochromic pigment material or (b) a thermochromic pigment and polymer mixture.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: July 16, 2024
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Ayman Abouraddy, Joshua Kaufman, Felix Tan, Morgan Monroe
  • Patent number: 12040094
    Abstract: An example method for training a graph convolutional neural network (GCNN) configured for virtual screening of molecules for drug discovery is described herein. The method can include receiving a first data set including a plurality of molecules, and training the GCNN to initialize one or more parameters of the GCNN using the first data set. The method can also include receiving a second data set including a plurality of molecules and respective inhibition rates for a disease, and training the GCNN to refine the one or more parameters of the GCNN using the second data set. The molecules in the first and second data sets can be expressed in a computer-readable format. An example method for virtually screening molecules on Plasmodium falciparum (P. falciparum) is also described herein.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: July 16, 2024
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Jiann-Shiun Yuan, Debopam Chakrabarti, Milad Salem, Arash Keshavarzi Arshadi
  • Publication number: 20240231097
    Abstract: An optical display system and a head-mounted display electronics apparatus are disclosed. The optical display system comprises: an image-generating apparatus, which generates image light; and an image-viewing apparatus, which guides the image light to eyes of a viewer, wherein the image-viewing apparatus comprises an imaging optical assembly and a multifocal assembly placed, the multifocal assembly has at least two optical powers and is programmable to choose at least one of the optical powers at a given time.
    Type: Application
    Filed: December 31, 2021
    Publication date: July 11, 2024
    Applicants: University of Central Florida Research Foundation, Inc., Goertek Inc.
    Inventors: JIANGHAO XIONG, Tao Zhan, Junyu Zou, Kun Li, Shin-Tson Wu
  • Publication number: 20240235475
    Abstract: Photoluminescence and electroluminescence are essential characterization techniques for photovoltaics cells and modules. For electroluminescence, the main technical challenge is easily injecting current into the photovoltaic to cause luminescence. The technique described herein enables daylight electroluminescence imaging without the need for external power sources. For photoluminescence, characterization is performed on photovoltaic cells, modules, strings, and arrays in daylight and without temporary mounting of LED modulators. Instead, the modulation is performed using a permanent electronic module installed within the electric circuit on the DC side. This enables automation or triggering of modulation on demand, 100% inspection without changes in hardware configuration because the cells are never shaded and provides a path to high throughput imaging.
    Type: Application
    Filed: November 8, 2023
    Publication date: July 11, 2024
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventors: Hubert Seigneur, Ryan Smith
  • Patent number: 12029447
    Abstract: A laparoscopic surgery support system can include a plurality of ports configured to receive a trocar therethrough and a plurality of arms connecting the plurality of ports together and configured to allow fixation of a relative position of the plurality of ports. For example, the plurality of ports can include three or more ports.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: July 9, 2024
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Sang-Eun Song, Eric Barker, Israel Camacho, Tanner Drake, Immanuel Girgis, Matthew Hook, Karina Thomas, Alex Zaffos