Abstract: The present disclosure relates to wound treatment and therapy and the promotion of tissue regeneration following injury. In particular, it relates to a microRNA-146a and nanoceria conjugate for improving wound healing and, in some embodiments, preventing adverse ventricular remodeling following myocardial infarction.
Type:
Grant
Filed:
November 23, 2016
Date of Patent:
December 5, 2023
Assignees:
THE REGENTS OF THE UNIVERSITY OF COLORADO, UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
Inventors:
Kenneth Liechty, Sudipta Seal, Robert Gorman
Abstract: A nanoparticle for use within a composition for treating tomatoes as well as other agricultural products comprises: (1) a first shell layer comprising a leachant permeable base material in addition to a multi-valent metal (i.e., typically copper) material; and (2) a second shell layer comprising a Quat material. Due to the multi-valent metal material and the Quat, the nanoparticle and the composition provide superior performance when treating tomatoes.
Type:
Application
Filed:
August 9, 2023
Publication date:
November 30, 2023
Applicant:
UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
Inventors:
Swadeshmukul Santra, Ali Ozcan, Mikaeel Young
Abstract: Interaction of acoustic waves in a piezoelectric-semiconductor resonant cavity with the charge carriers in the semiconductor layer can be directed toward amplification of the acoustic waves; such amplification scheme can be applied in building unilateral amplifiers, zero loss filters, oscillators, high detection range circuit-less wireless sensors, isolators, duplexers, circulators and other acoustic devices. An apparatus for acoustoelectric amplification is described. The apparatus includes a semiconductor layer and a thin piezoelectric layer bonded (or deposited) onto the semiconductor layer forming an acoustic cavity. Two or more tethers forming a current conduction path through the semiconductor layer and two or more access pads to silicon are positioned on two ends of the acoustic cavity and configured to inject a DC current in the semiconductor layer.
Type:
Grant
Filed:
July 20, 2020
Date of Patent:
November 21, 2023
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: Disclosed herein are microfluidic systems with recirculation of fluid and computer-implemented methods of calculating conditions within the microfluidic systems. The microfluidic systems include a computing device and a microfluidic device having first and second reservoirs, at least one chamber, and a fluid path connecting the first reservoir, the chamber, and the second reservoir. The methods for calculating conditions include receiving a first reservoir fluid volume, a second reservoir fluid volume, a first concentration, and a second concentration. The methods further include receiving a time-dependent imposed pressure difference between the first reservoir and the second reservoir, then determining a hydraulic pressure difference and an effective pressure difference. The effective pressure difference is used to account for reactions occurring within the microfluidic device and to determine the value of the condition within the microfluidic device.
Type:
Grant
Filed:
September 9, 2022
Date of Patent:
November 7, 2023
Assignee:
University of Central Florida Research Foundation
Inventors:
James Hickman, Kazi Tasneem, Christopher Long
Abstract: An adaptive system and a method for adjusting a parameter in the adaptive system includes operating an adaptive system with an output signal produced from an input signal applied to an input, in which a parameter with a finite range is determined based on a difference between the output signal and a target output signal. In one example the parameter with the finite range is a fixed-point parameter or an analog parameter. The parameter is accessed from the adaptive system. A probability distribution of the parameter is assigned. The finite range for the parameter is updated based on the probability distribution which has been assigned. The probability distribution function may be updated alone with the finite range of the parameter. The probability distribution may be derived from one or more historical values of the parameter, and a plurality of system parameters belonging to an identical category of data as the parameter.
Type:
Grant
Filed:
September 21, 2020
Date of Patent:
November 7, 2023
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: A system and method for converting a radio frequency (RF) to a direct current (DC) signal by generating acoustic phonons from the received RF signal utilizing a piezoelectric material. The acoustic phonons of the RF signal interact with the electrons of a semiconductive material to generate a DC signal that is proportional to the power of the RF signal. The DC signal can be used to power devices or can be interpreted as a measure of a local RF frequency spectrum.
Type:
Grant
Filed:
May 5, 2023
Date of Patent:
November 7, 2023
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: A three-way catalyst for reduced palladium loading is provided. The catalyst includes an inert substrate and a palladium catalyst material coating the substrate. The palladium catalyst material includes a support material formed from one of 10% CeO2/Al2O3, 20% CeO2—Al2O3 (20CeAlOy), 30% CeO2—Al2O3 (30CeAlOy), Al2O3, and MOx-Al2O3, wherein M is one of copper, iron, manganese, titanium, zirconium, magnesium, strontium, and barium. The palladium catalyst material includes a layer of CeO2 material disposed upon the support material, wherein the layer of CeO2 material is dispersed on a surface of the support material. The palladium catalyst material includes an active component including a layer of praseodymium oxide particles dispersed across the surface of the layer of CeO2 material and a layer of palladium particles disposed upon and dispersed across the surface of the layer of CeO2 material at locations each corresponding to a respective location of each of the praseodymium particles.
Type:
Grant
Filed:
April 21, 2022
Date of Patent:
October 31, 2023
Assignees:
GM GLOBAL TECHNOLOGY OPERATIONS LLC, University of Central Florida Research Foundation, Inc., BASF Corporation
Abstract: A three-way catalyst for reduced palladium loading is provided. The catalyst includes an inert substrate and a palladium catalyst material coating the substrate. The palladium catalyst material includes a support material formed from one of 10% CeO2/Al2O3, 20% CeO2—Al2O3 (20CeAlOy), 30% CeO2—Al2O3 (30CeAlOy), Al2O3, and MOx-Al2O3, wherein M is one of copper, iron, manganese, titanium, zirconium, magnesium, strontium, and barium. The palladium catalyst material includes a layer of CeO2 material disposed upon the support material, wherein the layer of CeO2 material is dispersed on a surface of the support material. The palladium catalyst material includes an active component including a layer of praseodymium oxide particles dispersed across the surface of the layer of CeO2 material and a layer of palladium particles disposed upon and dispersed across the surface of the layer of CeO2 material at locations each corresponding to a respective location of each of the praseodymium particles.
Type:
Application
Filed:
April 21, 2022
Publication date:
October 26, 2023
Applicants:
GM GLOBAL TECHNOLOGY OPERATIONS LLC, University of Central Florida, BASF Corporation
Abstract: A method for isolating at least one conductive via from a surrounding glass substrate is provided. A support layer is formed over at least one surface of the glass substrate. Thereafter, the glass substrate is removed. As a result, the at least one conductive via can be analyzed without interference from the glass substrate.
Type:
Grant
Filed:
May 28, 2021
Date of Patent:
October 24, 2023
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: One or more cameras capture objects at a higher resolution than the human eye can perceive. Objects are segmented from the background of the image and scaled to human perceptible size. The scaled-up objects are superimposed over the unscaled background. This is presented to a user via a display whereby the process selectively amplifies the size of the objects' spatially registered retinal projection while maintaining a natural (unmodified) view in the remainder of the visual field.
Type:
Grant
Filed:
June 29, 2022
Date of Patent:
October 24, 2023
Assignee:
University of Central Florida Research Foundation, Inc.
Inventors:
Gerd Bruder, Gregory Welch, Kangsoo Kim, Zubin Choudhary
Abstract: A sensor device is for detecting metal. The sensor device may have a substrate, an electrode on the substrate, and a biopolymer-metal composite film on the electrode. The biopolymer-metal composite film may include a metal and a biopolymer. The sensor device may further have circuitry coupled to the electrode and configured to apply a sensing signal to the electrode.
Type:
Grant
Filed:
August 6, 2019
Date of Patent:
October 10, 2023
Assignee:
UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
Abstract: A layered catalyst structure for purifying an exhaust gas stream includes a catalyst support and a palladium catalyst layer including an atomic dispersion of palladium ions electrostatically adsorbed onto an exterior surface of the catalyst support. The catalyst support includes an alumina substrate, a first ceria layer disposed on and extending substantially continuously over the alumina substrate, and a second colloidal ceria layer formed directly on the first ceria layer over the alumina substrate. The palladium catalyst layer is formed on the exterior surface of the catalyst support by applying a palladium-containing precursor solution to the exterior surface of the catalyst support and then heating the catalyst support and the palladium-containing precursor solution. The palladium-containing precursor solution includes a positively charged palladium complex in an aqueous medium and has a pH greater than a point of zero charge of the second colloidal ceria layer.
Type:
Grant
Filed:
January 21, 2022
Date of Patent:
October 3, 2023
Assignees:
GM GLOBAL TECHNOLOGY OPERATIONS LLC, UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
Abstract: A method can include milling a powder with a test grinding media, and determining an amount of abraded grinding media that abrades from the test grinding media into the powder due to the milling of the powder. The method can include creating a compensated powder to account for the amount of the abraded grinding media such that the powder milling process results in a desired powder composition.
Type:
Application
Filed:
March 17, 2023
Publication date:
September 21, 2023
Applicant:
University of Central Florida Research Foundation, Inc.
Abstract: This disclosure relates to an intermolecularly-fabricated composition for capturing plant materials, agrochemicals and pharmaceuticals which can simultaneously capture inorganic particulates and organic compounds in which the capture materials have mutual chemical affinity with the composition matrix thereby exhibiting an adhesive property.
Type:
Application
Filed:
March 14, 2023
Publication date:
September 21, 2023
Applicant:
University of Central Florida Research Foundation, Inc.
Inventors:
Jorge Pereira, Giuliana Gan Giannelli, Edwin Davidson, Swadeshmukul Santra, Sebastian Leon
Abstract: Disclosed herein are polyamine transport inhibitors (PTI) and methods of use as antivirals. Disclosed PTI compounds are useful as treatments for viral infections or can be used as prophylactic agents that protect high risk individuals from becoming infected by the virus. The disclosed PTI compounds can be used alone or in combination with other agents (or other antivirals) to improve patient outcomes such as DFMO (or Remdesivir).
Type:
Grant
Filed:
September 8, 2021
Date of Patent:
September 12, 2023
Assignees:
University of Central Florida Research Foundation, Inc., Boston University
Abstract: A QCL may include a substrate, an emitting facet, and semiconductor layers adjacent the substrate and defining an active region. The active region may have a longitudinal axis canted at an oblique angle to the emitting facet of the substrate. The QCL may include an optical grating being adjacent the active region and configured to emit one of a CW laser output or a pulsed laser output through the emitting facet of substrate.
Type:
Grant
Filed:
October 11, 2022
Date of Patent:
September 12, 2023
Assignee:
UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
Abstract: A method of forming a high-throughput, three-dimensional (3D) microelectrode array for in vitro electrophysiological applications includes 3D printing a well plate having a top face and bottom face. A plurality of culture well each includes a plurality of 3D printed, vertical microchannels and microtroughs communicating with the microchannels. The microtroughs and the microchannels are filled with a conductive paste to form self-isolated microelectrodes in each of the culture wells and conductive traces that communicate with the self-isolated microelectrodes.
Type:
Grant
Filed:
June 16, 2021
Date of Patent:
September 5, 2023
Assignee:
UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
Inventors:
Swaminathan Rajaraman, Avra Kundu, Adam Rozman, Jorge Manrique Castro
Abstract: A method of detecting and diagnosing cancers characterized by the presence of at least one nodule/neoplasm from an imaging scan is presented. To detect nodules in an imaging scan, a 3D CNN using a single feed forward pass of a single network is used. After detection, risk stratification is performed using a supervised or an unsupervised deep learning method to assist in characterizing the detected nodule/neoplasm as benign or malignant. The supervised learning method relies on a 3D CNN used with transfer learning and a graph regularized sparse MTL to determine malignancy. The unsupervised learning method uses clustering to generate labels after which label proportions are used with a novel algorithm to classify malignancy. The method assists radiologists in improving detection rates of lung nodules to facilitate early detection and minimizing errors in diagnosis.
Type:
Grant
Filed:
November 4, 2019
Date of Patent:
August 22, 2023
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: A device may analyze a plurality of entries of a data set. The plurality of entries identify a plurality of variables. Each entry indicates a co-occurrence of variables of different types. The device may identify, based on analyzing the plurality of entries, variables of a first type and variables of a second type. The device may determine relationships between the variables of the first type and variables of the second type based on co-occurrences indicated by the plurality of entries. The relationships are determined without determining meaning of the variables of the first type and the variables of the second type. The device may detect a display size of a display device. The device may determine, based on the display size, a subset of the network diagram to provide to the display device and may provide the subset of the network diagram to the display device.
Type:
Application
Filed:
February 13, 2023
Publication date:
August 17, 2023
Applicant:
University of Central Florida Research Foundation, Inc.