Patents Assigned to University of Houston System
  • Patent number: 11028659
    Abstract: Improved drilling systems and methods may include piezoelectric actuator(s) in a drill string at one or more locations to minimize or eliminate stick-slip while drilling. For example, piezoelectric actuators may be incorporated into the rock bit or drill bit in the openings in the bit body for receiving the cutters. As another example, the piezoelectric actuators may be incorporated into an independent module that is place on or in the drill string. The independent module may be placed between the top drive and the drill bit or at the top of the drill string near a top drive.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: June 8, 2021
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Gangbing Song, Devendra Patil, Qingzhao Kong, Robello Samuel
  • Publication number: 20210155845
    Abstract: A composition composed of highly reactive metal particles that are ball milled, bead milled or blended and dispersed in a solvent with/without polymer for significantly reducing the viscosity of heavy oil for extracting viscous heavy oil, such that the composition reacts with water and oil to produce heat, H2 gas, and hydroxide to lower the oil viscosity and facilitate extraction from an underground formation or transport of heavy oil, such as in a pipe from one place to another place.
    Type: Application
    Filed: November 23, 2020
    Publication date: May 27, 2021
    Applicant: University of Houston System
    Inventors: Zhifeng Ren, Dan Luo
  • Publication number: 20210135184
    Abstract: A method of manufacturing an electrode by disposing a three-dimensional substrate in a metal nitrate solution, drying, and thermally phosphatizing with a phosphorus source under inert gas to form a metal based phosphate catalyst on the substrate. An electrocatalyst and electrode produced via the method are also provided.
    Type: Application
    Filed: March 12, 2018
    Publication date: May 6, 2021
    Applicant: University of Houston System
    Inventors: Zhifeng Ren, Shuo Chen, Fang Yu, Haiqing Zhou
  • Publication number: 20210129377
    Abstract: A 4-dimensional printing system and method for printing reinforced concrete may allow reinforced concrete elements to be printed freeform and/or fully automated without the need for formwork, molding, or labor. The printing system may include software and hardware systems. The software system may process 3D models of the reinforced concrete element desired into multiple layers. The software system may utilize the individual layer to control operation of the hardware system to print the desired reinforced concrete element layer-by-layer. The hardware system may provide a concrete nozzle, a reinforcement material nozzle, as well as dispensing mechanisms for printing the materials at the desired locations and/or at desired times for the individual layer being printed. The hardware system may also include motion control mechanism(s) that allow the position of the nozzles to be moved side-to-side, up and down, and towards or away relative to the element being printed as desired during the printing process.
    Type: Application
    Filed: January 17, 2018
    Publication date: May 6, 2021
    Applicant: University of Houston System
    Inventors: Yi-Lung Mo, Cunjiang Yu, Jamshaid Sawab
  • Publication number: 20210135581
    Abstract: A single phase single stage level-1 electric vehicle (EV) battery charger can control the power flow in both directions. The converter efficiency is high as the devices undergo ZCS which reduces switching loss in the devices. This converter does not require any intermediate DC link capacitor stage and the power density of the converter is high.
    Type: Application
    Filed: August 2, 2018
    Publication date: May 6, 2021
    Applicant: University of Houston System
    Inventors: Kaushik Rajashekara, Parthasarathy Nayak, Sumit Kumar Pramanick
  • Patent number: 10991836
    Abstract: A semiconductor device and method for fabricating same is disclosed. Embodiments are directed to a semiconductor device and fabrication of same which include a polycrystalline or amorphous substrate. An electrically conductive Ion Beam-Assisted Deposition (IBAD) template layer is positioned above the substrate. At least one electrically conductive hetero-epitaxial buffer layer is positioned above the IBAD template layer. The at least one buffer layer has a resistivity of less than 100 ??cm. The semiconductor device and method foster the use of bottom electrodes thereby avoiding complex and expensive lithography processes.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: April 27, 2021
    Assignee: University of Houston System
    Inventor: Venkat Selvamanickam
  • Publication number: 20210117686
    Abstract: Preferred embodiments described herein relate to a pipeline framework that allows for customized analytic processes to be performed on multiple streams of videos. An analytic takes data as input and performs a set of operations and transforms it into information. The methods and systems disclosed herein include a framework (1) that allows users to annotate and create variable datasets, (2) to train computer vision algorithms to create custom models to accomplish specific tasks, (3) to pipeline video data through various computer vision modules for preprocessing, pattern recognition, and statistical analytics to create custom analytics, and (4) to perform analysis using a scalable architecture that allows for running analytic pipelines on multiple streams of videos.
    Type: Application
    Filed: October 15, 2020
    Publication date: April 22, 2021
    Applicant: University of Houston System
    Inventors: Shishir K. Shah, Pranav Mantini
  • Patent number: 10961564
    Abstract: A methodology for assays and diagnostics utilizes a nanoporous or corrugated metal-containing surface, fiber or particle which enhances or suppresses the optical detectability of a label. The resulting optical, electromagnetic, or imaging signal signals the presence of a pathogen or analyte of interest. Preferred embodiments pertain to label-free, in situ monitoring of individual DNA hybridization in microfluidics using molecular sentinel probes immobilized on nanoporous gold disks. By immobilizing molecular sentinel probes on nanoporous gold disks, single-molecule sensitivity is demonstrated via surface-enhanced Raman scattering which provides robust signals. The described methodology is generally applicable to most amplification independent assays and molecular diagnostics.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: March 30, 2021
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Wei-Chuan Shih, Richard Willson
  • Publication number: 20210078052
    Abstract: Systems and methods for the ultrasonic disruption of biofilm and algae growth on underwater structures utilize an ultrasonic actuator (10) that produces a natural frequency in the ultrasonic range. In some embodiments, the ultrasonic actuator (10) includes one or more piezoelectric transducers (110).
    Type: Application
    Filed: March 20, 2018
    Publication date: March 18, 2021
    Applicant: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Gangbing Song, Siu Chun Michael Ho, Devendra Patil
  • Patent number: 10948411
    Abstract: Disclosed are methods of detecting one or more analytes in a sample by: (1) associating the sample with a surface that includes an analyte binding agent to result in the immobilization of the analytes on the surface; (2) contacting the analyte with a composition that includes at least one phosphor compound with an affinity for the analyte; (3) formation of immobilized analyte binding agent-analyte-phosphor complexes on the surface; (4) separating unbound phosphor compounds from the immobilized complexes; (5) detecting a presence or absence of a luminescence signal from the immobilized complexes; and (6) correlating the luminescence signal to the presence or absence of the analyte in the sample. The phosphor compound may include (Sr1-?Ba?)2-j-kMgSi2O7:EujDyk, (Sr1-?Ba?)2-xMgSi2O7:Eu2+Dy3+, (Sr1-?Ba?)2MgSi2O7:Eu2+Dy3+, (Sr1-?Ba?)2-xMgSi2O7:Eu2+, and combinations thereof.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: March 16, 2021
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Jakoah Brgoch, Erin Finley, Andrew Paterson, Richard Willson
  • Patent number: 10947117
    Abstract: A method of restoring the proton conductivity of a sintered pyrophosphate membrane of intermediate temperature fuel cells (IT-FCs) by introducing phosphoric acid into the sintered SnP2O7 membrane to react with the degraded SnP2O7 species and thus restore the membrane pyrophosphate and proton conductivity. Such cells operate with low external humidification, and the active area of the cells may be fabricated up to 100 cm2 in size.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: March 16, 2021
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Anima B. Bose, Wei Li
  • Publication number: 20210069294
    Abstract: Loss of cardiomyocytes underlies most causes of heart failure, and normal repair processes are inadequate to deal with extensive myocardial damage. The inventors have identified mutations of the N-terminus of serum respose factor (SRF)'s MADS box, termed STEMINs, that block cardiac differentiation, but also powerfully activate the stem cell marker genes Nanog and Octomer 4, as well as cyclins, which promotes adult myocyte replication. SRF Stemin mutations are not cardiac-specific, and also propel mammalian fibroblasts into a proliferative state. Thus, STEMINs may be useful for regeneration of all tissue and organ types, by activating partial pluripotency programs and enhancing repair by increased cell replication. Following withdrawal of STEMINs, the cells then return to normal cell identity.
    Type: Application
    Filed: December 31, 2018
    Publication date: March 11, 2021
    Applicant: University of Houston System
    Inventors: Robert J. SCHWARTZ, Dinakar IYER
  • Publication number: 20210066748
    Abstract: A class of improved solid-state electrolytes and methods for forming such electrolytes are discussed herein. The improved electrolytes may be a sodium oxy-sulfide, such as with a nominal composition of Na3PS4 _xOx (0<x?2). The electrolytes can be synthesized from using a simple one-step ball-milling method. The ball-milling may be performed at high rotation speeds. The resulting ball-milled materials may further be optionally pressed. The pressing may be performed at low or room temperatures and/or relatively low pressure, and the resulting electrolytes achieve high relative densities. The solid-state electrolyte forms a highly dense layer that approaches a continuous glass that is nearly flawless, is mainly amorphous, and/or maintains a stable low-resistance interface with Na metal and Na-alloy electrodes.
    Type: Application
    Filed: January 14, 2019
    Publication date: March 4, 2021
    Applicant: University of Houston System
    Inventors: Yan Yao, Xiaowei Chi
  • Publication number: 20210062145
    Abstract: The present invention relates to a culture media system that is useful for the isolation and epigenetically stable propagation of normal stem cells in culture which are derived from columnar epithelial tissues and cancer stem cells from epithelial cancers. In certain embodiments, the culture system is a feeder-free system.
    Type: Application
    Filed: December 28, 2018
    Publication date: March 4, 2021
    Applicants: University of Houston System, Tract Pharmaceuticals, Inc.
    Inventors: Wa XIAN, Frank McKEON, Marcin DULEBA, Matthew P. VINCENT
  • Patent number: 10934475
    Abstract: A Janus graphene nanosheet (JGN) surfactant formed from a two-dimensional graphene oxide sheet and functionalized to produce an amphiphilic graphene nanosheet. The JGN may be a component of a nanofluid utilized in nanofluid flooding for oil recovery. The JGN may also be used as solid surfactants to form emulsions for oil recovery.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: March 2, 2021
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Zhifeng Ren, Feng Wang, Dan Luo
  • Patent number: 10930834
    Abstract: Discussed herein are systems and methods for fabrication of MgSnGe-based thermoelectric materials for applications from room temperature and near room temperature to high temperature applications. The TE materials may be fabricated by hand or ball milling a powder to a predetermined particle size and hot-pressing the milled powder to form a thermoelectric component with desired properties including a figure of merit (ZT) over a temperature range. The TE materials fabricated may be disposed in thermoelectric devices for varying applications.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: February 23, 2021
    Assignee: University of Houston System
    Inventors: Zhifeng Ren, Weishu Liu
  • Publication number: 20210041395
    Abstract: A method of measuring dissociation of the biomolecular bonds in one or multiple sample wells using super-resolution force spectroscopy (SURFS). SURFS utilizes precise ultrasound radiation to exert an acoustic radiation force on the biomolecular bonds labeled with magnetic particles. The force-induced dissociation of the protein bonds labeled with magnetic particles may be measured as a reduced magnetic signal by a magnetic sensor. The force resolution allows for differentiating biomolecular bonds with an extremely high level of precision. The biomolecular bonds include protein-protein, protein-nucleic acid, nucleic acid-nucleic acid, small molecule-protein, and small molecule-nucleic acid interactions.
    Type: Application
    Filed: February 8, 2018
    Publication date: February 11, 2021
    Applicant: University of Houston System
    Inventors: Shoujun Xu, Yuhong Wang, Haina Jia, Heng Yin, Yujia Mao
  • Patent number: 10897120
    Abstract: Externally-strained devices such as LED and FET structures as discussed herein may have strain applied before or during their being coupled to a housing or packaging substrate. The packaging substrate may also be strained prior to receiving the structure. The strain on the devices enables modulation of light intensity, color, and electrical currents in some embodiments, and in alternate embodiments, enables a fixed strain to be induced and maintained in the structures.
    Type: Grant
    Filed: September 29, 2018
    Date of Patent: January 19, 2021
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Jae-Hyun Ryou, Shahab Shervin, Seung Hwan Kim
  • Patent number: 10874724
    Abstract: In some embodiments the present disclosure pertains to a method of activating an anti-tumor immune response for the treatment of a cancer. In some embodiments, such a method comprises detecting CD26 expression in a subject in need thereof. In some embodiments, the method comprises administering to the subject a therapeutically effective amount of a composition comprising adenosine deaminase. In some embodiments, the adenosine deaminase stimulates T cell proliferation and activates maturation of macrophages or dendritic cells. In some embodiments, the present disclosure pertains to a method for targeted reduction of adenosine or deoxyadenosine in a tumor microenvironment of a solid tumor.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: December 29, 2020
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: Navin Varadarajan, Irfan Naseem Bandey
  • Publication number: 20200377675
    Abstract: A facile and scalable method to prepare graphene-based amphiphilic Janus nanosheets with high efficiency utilizing the formation of hydrogen bonding to immobilize graphene oxide (GO) on the surfaces of starch microspheres. After selective functionalization of the exposed surface using alkylamine, amphiphilic Janus nanosheets (AJN) were obtained by releasing the nanosheets from the starch microspheres.
    Type: Application
    Filed: July 27, 2018
    Publication date: December 3, 2020
    Applicant: University of Houston System
    Inventors: Zhifeng Ren, Dan Luo, Feng Wang