Patents Assigned to University of Houston System
  • Publication number: 20240287603
    Abstract: Embodiments of the present disclosure pertain to methods of utilizing force-modulated hybridization to determine the length of an analyte strand, to determine an unknown nucleic acid sequence, or to determine the binding of a nucleotide to an active agent. Additional embodiments of the present disclosure pertain to sample holder devices and methods of utilizing such devices. Further embodiments of the present disclosure pertain to detection devices.
    Type: Application
    Filed: May 2, 2024
    Publication date: August 29, 2024
    Applicant: University of Houston System
    Inventors: Shoujun Xu, Qiongzheng Hu, Yuhong Wang
  • Publication number: 20240288518
    Abstract: In an embodiment, the present disclosure pertains to electric field generators that include a signal generator electrically connected to a power amplifier, a impedance matching circuit electrically connected to the power amplifier, and a power divider electrically connected to the impedance matching circuit and to at least one of a first wall, a second wall, a third wall, a fourth wall, or a base area. In an additional embodiment, the present disclosure pertains to method of determining radio frequency (RF)-induced heating on a medical device utilizing an electric field generator of the present disclosure. Additional embodiments of the present disclosure pertain to methods of making electric field generators for testing a medical device.
    Type: Application
    Filed: May 6, 2024
    Publication date: August 29, 2024
    Applicant: University of Houston System
    Inventors: Ji Chen, Jianfeng Zheng
  • Publication number: 20240281061
    Abstract: A system for tracking an eye of a user includes one or more piezoelectric sensors positionable on the face of the user, and an eye tracking computer system in signal communication with the one or more piezoelectric sensors so as to receive signals from the one or more piezoelectric sensors, wherein the computer system is configured to detect movement in at least one direction of the eye of the user based on the signals received by the computer system from the one or more piezoelectric sensors when the one or more piezoelectric sensors are positioned on the face of the user in one or more locations each spaced from the eyelids of the user.
    Type: Application
    Filed: June 21, 2022
    Publication date: August 22, 2024
    Applicant: University of Houston System
    Inventors: Jae-Hyun Ryou, Nam-In Kim
  • Patent number: 12061018
    Abstract: A method for full spectrum solar thermal energy harvesting and collection includes storing a first heat in a phase change material in the presence of solar radiation based on absorbing full spectrum solar radiation, harvesting a second heat from the phase change material in the presence of solar radiation, storing molecular energy in a molecular storage material in the presence of solar radiation based on absorbing full spectrum solar radiation, transferring the second heat from the phase change material to the molecular storage material in the absence of solar radiation, and harvesting the molecular energy released by the molecular storage material.
    Type: Grant
    Filed: June 24, 2020
    Date of Patent: August 13, 2024
    Assignee: University of Houston System
    Inventors: Hadi Ghasemi, Varun Kashyap, T. Randall Lee, Siwakorn Sakunkaewkasem
  • Patent number: 12042525
    Abstract: Loss of cardiomyocytes underlies most causes of heart failure, and normal repair processes are inadequate to deal with extensive myocardial damage. The inventors have identified mutations of the N-terminus of serum response factor (SRF)'s MADS box, termed STEMINs, that block cardiac differentiation, but also powerfully activate the stem cell marker genes Nanog and Octomer 4, as well as cyclins, which promotes adult myocyte replication. SRF Stemin mutations are not cardiac-specific, and also propel mammalian fibroblasts into a proliferative state. Thus, STEMINs may be useful for regeneration of all tissue and organ types, by activating partial pluripotency programs and enhancing repair by increased cell replication. Following withdrawal of STEMINs, the cells then return to normal cell identity.
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: July 23, 2024
    Assignee: University of Houston System
    Inventors: Robert J. Schwartz, Dinakar Iyer
  • Patent number: 12013449
    Abstract: In an embodiment, the present disclosure pertains to electric field generators that include a signal generator electrically connected to a power amplifier, a impedance matching circuit electrically connected to the power amplifier, and a power divider electrically connected to the impedance matching circuit and to at least one of a first wall, a second wall, a third wall, a fourth wall, or a base area. In an additional embodiment, the present disclosure pertains to method of determining radio frequency (RF)-induced heating on a medical device utilizing an electric field generator of the present disclosure. Additional embodiments of the present disclosure pertain to methods of making electric field generators for testing a medical device.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: June 18, 2024
    Assignee: University of Houston System
    Inventors: Ji Chen, Jianfeng Zheng
  • Patent number: 12006542
    Abstract: Embodiments of the present disclosure pertain to methods of utilizing force-modulated hybridization to determine the length of an analyte strand, to determine an unknown nucleic acid sequence, or to determine the binding of a nucleotide to an active agent. Additional embodiments of the present disclosure pertain to sample holder devices and methods of utilizing such devices. Further embodiments of the present disclosure pertain to detection devices.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: June 11, 2024
    Assignee: University of Houston System
    Inventors: Shoujun Xu, Qiongzheng Hu, Yuhong Wang
  • Publication number: 20240173705
    Abstract: Interconnected zeolite nanosheets with a structural motif resembling self-pillared pentasil zeolites are synthesized through the use of MEL or MFI-type zeolites as crystalline seeds. The use of MEL- or MFI-type zeolites as crystalline seeds induces the spontaneous formation of pillared zeolites, thus avoiding, for the first time, the use of any organic or branching template for the crystallization of these hierarchical structures.
    Type: Application
    Filed: February 16, 2022
    Publication date: May 30, 2024
    Applicant: University of Houston System
    Inventors: Jeffrey D. Rimer, Rishabh Jain
  • Publication number: 20240175870
    Abstract: Presented herein are methods of evaluating cellular activity by: placing a cell population on an area; assaying for a dynamic behavior of the cell population as a function of time; identifying cell(s) of interest based on the dynamic behavior; characterizing a molecular profile of the cell(s); and correlating the obtained information. The assayed dynamic behavior can include cellular activation, cellular inhibition, cellular interaction, protein expression, protein secretion, cellular proliferation, changes in cellular morphology, motility, cell death, cell cytotoxicity, cell lysis, and combinations thereof. Sensors associated with the area may be utilized to facilitate assaying. Molecular profiles of the cell(s) can then be characterized by various methods, such as DNA analysis, RNA analysis, and protein analysis.
    Type: Application
    Filed: August 18, 2023
    Publication date: May 30, 2024
    Applicant: University of Houston System
    Inventors: Navin Varadarajan, Gabrielle Romain, Ivan Liadi, Victor G. Sendra, Badrinath Roysam
  • Publication number: 20240158756
    Abstract: The present invention relates to a culture media system that is useful for the isolation and epigenetically stable propagation of normal stem cells in culture, wherein the stem cells are derived from stratified epithelial tissues and cancer stem cells from epithelial cancers. In certain embodiments, the culture system is a feeder-free system.
    Type: Application
    Filed: October 9, 2020
    Publication date: May 16, 2024
    Applicant: University of Houston System
    Inventors: Frank McKEON, Wa XIAN, Matthew P. VINCENT, Jingzhong XIE, Wei RAO
  • Patent number: 11976153
    Abstract: Described herein are polymerization catalysts having a structure according to formula (1): wherein is a diimine ligand, A? is a counter anion, and R2 is a fluorinated alkane, alkene or alkyne, a fluorinated aromatic, a fluorinated cycloalkane or cylcoalkene, a fluorinated heteroaromatic, or a fluorinated heterocyclic. Also described herein are polymers having a terminus having a structure according to Formula (3): wherein R2 is a fluorinated alkane, alkene or alkyne, a fluorinated aromatic, a fluorinated cycloalkane or cylcoalkene, a fluorinated heteroaromatic, or a fluorinated heterocyclic.
    Type: Grant
    Filed: May 18, 2023
    Date of Patent: May 7, 2024
    Assignee: University of Houston System
    Inventors: Eva Harth, Huong Dau
  • Patent number: 11964230
    Abstract: A system configured to capture CO2 and able to be washed of the captured CO2 includes a material including an ionic liquid configured to capture CO2 in response to exposure to a gas comprising CO2 and to a thermal energy source and an aerogel holding the ionic liquid therein. The system may also include a washing solution configured to wash the captured CO2 from the material.
    Type: Grant
    Filed: October 6, 2022
    Date of Patent: April 23, 2024
    Assignee: University of Houston System
    Inventors: Hadi Ghasemi, Varun Kashyap, T. Randall Lee, Riddhiman Medhi
  • Patent number: 11959002
    Abstract: Provided herein are phosphors of the general molecular formula: (A2-2xEux)(Mg1-yCay)PO4F wherein the variables are as defined herein. Methods of producing the phosphors are also provided. In some aspects, the present disclosure provides light-emitting devices comprising these phosphors.
    Type: Grant
    Filed: November 19, 2021
    Date of Patent: April 16, 2024
    Assignee: University of Houston System
    Inventors: Jakoah Brgoch, Shruti Hariyani
  • Patent number: 11923105
    Abstract: An MOCVD system fabricates high quality superconductor tapes with variable thicknesses. The MOCVD system can include a gas flow chamber between two parallel channels in a housing. A substrate tape is heated and then passed through the MOCVD housing such that the gas flow is perpendicular to the tape's surface. Precursors are injected into the gas flow for deposition on the substrate tape. In this way, superconductor tapes can be fabricated with variable thicknesses, uniform precursor deposition, and high critical current densities.
    Type: Grant
    Filed: August 15, 2022
    Date of Patent: March 5, 2024
    Assignee: University of Houston System
    Inventors: Goran Majkic, Venkat Selvamanickam
  • Patent number: 11910727
    Abstract: An ultra-thin film superconducting tape and method for fabricating same is disclosed. Embodiments are directed to a superconducting tape being fabricated by processes which include removing a portion of the superconducting tape's substrate subsequent the substrate's initial formation, whereby a thickness of the superconducting tape is reduced to 15-80 ?m.
    Type: Grant
    Filed: April 18, 2022
    Date of Patent: February 20, 2024
    Assignee: University of Houston System
    Inventor: Venkat Selvamanickam
  • Patent number: 11901097
    Abstract: A round superconductor wire and method for fabricating same are disclosed. Embodiments are directed to a round superconductor wire including at least two superconductor tapes wound on a wire former. Each superconductor tape includes: bottom stabilizer and silver layers; substrate disposed above the bottom silver layer; buffer film stack disposed above the substrate; superconductor film disposed above the buffer film stack; top silver layer disposed above the superconductor film; and top stabilizer layer disposed above the top silver layer. At least one of the bottom stabilizer layer, bottom silver layer, substrate, buffer film stack, superconductor film, top silver layer, or top stabilizer layer is of a different width, thickness, or material composition in one of the superconductor tapes than in another of the superconductor tapes. These and other embodiments achieve a round superconductor wire having improved current density in high magnetic field applications when made in small diameters.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: February 13, 2024
    Assignees: University of Houston System, AMPEERS LLC
    Inventors: Goran Majkic, Anis Ben Yahia, Wenbo Luo, Venkat Selvamanickam, Soumen Kar
  • Patent number: 11881328
    Abstract: A method and composition for doped HTS tapes having directional flux pinning and critical current.
    Type: Grant
    Filed: April 12, 2022
    Date of Patent: January 23, 2024
    Assignees: University of Houston System, SuperPower, Inc.
    Inventors: Venkat Selvamanickam, Yimin Chen
  • Publication number: 20240018388
    Abstract: Durable antibacterial coatings are prepared by inter-diffusing zwitterionic polyurethane in acrylic polyurethane. Bacterial attachment is substantially eliminated from the surface of the coatings due to the hydrophilicity of the zwitterionic polyurethane. Long-term antibacterial properties were observed for both Gram-negative and Gram-positive bacteria even when the coatings were constantly challenged by mechanical abrasion.
    Type: Application
    Filed: September 12, 2023
    Publication date: January 18, 2024
    Applicant: University of Houston System
    Inventors: Hadi Ghasemi, Zixu Huang
  • Patent number: 11865157
    Abstract: Described herein are pharmaceutical compositions containing peptoids of general formula (I), (II), or (III) capable of reducing proliferation of cancer stem cells in a subject and methods of treatment or prophylactic administration of these pharmaceutical compositions to treat cancer. Also provided herein are method of detecting and treating cancerous cell masses by use of peptoids of general formula (I), (II), or (III).
    Type: Grant
    Filed: January 20, 2023
    Date of Patent: January 9, 2024
    Assignees: University of Houston System, The Board of Regents of the University of Texas System
    Inventors: Damith Gomika Udugamasooriya, Aaron Raymond, John Minna
  • Publication number: 20230414566
    Abstract: Aryl-substituted acetamide and pyrrolidin-2-one (?-butyrolactam) derivatives have useful activity in the inhibition, prevention, or treatment of seizures. The derivatives may be useful in the treatment of epilepsy, including medically refractory epilepsy, and nerve agent poisoning.
    Type: Application
    Filed: September 7, 2023
    Publication date: December 28, 2023
    Applicant: University of Houston System
    Inventors: Anton Dubrovskiy, Arcadius V. Krivoshein