Patents Assigned to University of Ottawa
  • Patent number: 10004773
    Abstract: The disclosure provides compositions containing preparations from plants of the family Marcgraviaceae and from plants of the family Platanaceae. The disclosure also provides methods and uses of plant preparations for treating anxiety, stress and glucocorticoid related disorders.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: June 26, 2018
    Assignee: University of Ottawa
    Inventors: Tony Durst, John Douglas Baker, John Thor Arnason, Jose Miguel Wade, Zulfiquar Merali, Martha Mullally, Christian Cayer, Stanley J. Alkemade, Ana Francis Carballo, Iqubal Velji
  • Patent number: 9986754
    Abstract: Bacterial strains are provided that can be isolated from the microflora of lowbush blueberry (Vaccinium angustifolium), and that are capable of increasing the antioxidant content of their growth medium. The bacteria can be used, for example, to increase the antioxidant content of various foodstuffs, as probiotics or as additives to animal feed. Antioxidant-enriched compositions produced by fermentation processes utilizing the bacteria are also provided. The antioxidant-enriched compositions can be used in the preparation of cosmetics and nutritional supplements. The antioxidant-enriched compositions also have therapeutic applications.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: June 5, 2018
    Assignee: University of Ottawa
    Inventors: Chantal Matar, Luc J. Martin
  • Publication number: 20180112190
    Abstract: Provided are compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
    Type: Application
    Filed: January 26, 2016
    Publication date: April 26, 2018
    Applicants: Ottawa Hospital Research Institute, University of Ottawa
    Inventors: Jean-Simon Diallo, Christopher Noyce Boddy, Mark Dornan, Ramya Krishnan, Rozanne Arulanandam, Fabrice Le Boeuf, Jeffrey Smith, Andrew Macklin
  • Publication number: 20180043310
    Abstract: A method for fabricating a nanopore at a particular location in a membrane includes controlling a dielectric strength of the membrane at a particular location on the membrane while applying one of an electric potential or an electric current to the membrane, monitoring an electrical property across the membrane while one of the electric potential or the electric current is being applied across the membrane, detecting an abrupt change in the electrical property across the membrane while one of the electric potential or the electric current is being applied across the membrane; and removing the electric potential or the electric current from the membrane in response to detecting the abrupt change in the electrical property.
    Type: Application
    Filed: February 24, 2016
    Publication date: February 15, 2018
    Applicant: The University of Ottawa
    Inventors: Jose BUSTAMANTE, Kyle BRIGGS, Vincent TABARD-COSSA
  • Patent number: 9746748
    Abstract: A method and apparatus is disclosed for generating tunable attosecond-scale radiation pulses, with a frequency in range of mid-infrared to ultra-violet, from a silicon medium. The invention utilizes an intense laser pulse to drive a high harmonic generation (HHG) process in a silicon medium and a weak secondary field to control the HHG process. The weak secondary field has a frequency equal to the second harmonic of the intense laser pulse. The spatial, temporal and spectral properties of the HHG process and the emitted harmonic beam are tuned by adjusting the relative delay between the two fields and the intensity of the weak secondary field.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: August 29, 2017
    Assignee: University of Ottawa
    Inventors: Giulio Vampa, Paul B. Corkum
  • Publication number: 20170223996
    Abstract: Bacterial strains are provided that can be isolated from the microflora of lowbush blueberry (Vaccinium angustifolium), and that are capable of increasing the antioxidant content of their growth medium. The bacteria can be used, for example, to increase the antioxidant content of various foodstuffs, as probiotics or as additives to animal feed. Antioxidant-enriched compositions produced by fermentation processes utilising the bacteria are also provided. The antioxidant-enriched compositions can be used in the preparation of cosmetics and nutritional supplements. The antioxidant-enriched compositions also have therapeutic applications.
    Type: Application
    Filed: December 15, 2016
    Publication date: August 10, 2017
    Applicant: University of Ottawa
    Inventors: Chantal MATAR, Luc J. Martin
  • Publication number: 20170145459
    Abstract: The present invention relates to the cell-based production of bacterial nonulosonates and their biosynthetic precursors. Specifically, the present invention provides recombinant cells for the production of pseudaminic acid, legionaminic acid, UDP-2,4-diacetamido-2,4,6-trideoxy-?-L-altropyranose, and UDP-2,4-diacetamido-2,4,6-trideoxy-?-D-glucopyranose. Methods for producing the sugars are also provided.
    Type: Application
    Filed: November 17, 2016
    Publication date: May 25, 2017
    Applicants: National Research Council of Canada, University of Ottawa
    Inventors: Dennis M. WHITFIELD, Susan M. LOGAN, Ian C. SCHOENHOFEN, Christopher N. BODDY, Benjamin R. LUNDGREN
  • Patent number: 9644202
    Abstract: The disclosure relates to a switchable aptamer having a high affinity for a selected target such as a virus, cell or antibody when in the presence of a binding ion and a low affinity for said target in the absence of said binding ion. The switchable aptamer may be isolated from a pool comprising a mixture of aptamers by incubating the pool with the target ligand and a binding ion to form target-aptamer complexes; separating unbound aptamer molecules from the target-aptamer complexes; contacting the target-aptamer complexes with a chelating agent having affinity for the binding ion wherein a switchable aptamer specific to said target is released from the target-aptamer complexes; and isolating the switchable aptamer released in the preceding step.
    Type: Grant
    Filed: May 14, 2014
    Date of Patent: May 9, 2017
    Assignee: University of Ottawa
    Inventors: Maxim V. Berezovski, Mohamed Wehbe, Mahmoud Aziz Mahmoud Labib, Darija Muharemagic, Anna S. Zamay, Shahrokh Ghobadloo
  • Patent number: 9640942
    Abstract: A method and apparatus for launching optical pump signals into a disordered gain medium at two points thereby producing a narrow line-width random fiber laser within the disordered gain medium. The optical pump signals are propagated in a direction through the disordered gain medium towards one another. The apparatus may comprise an optical gain fiber having a first end configured to receive a first fiber pump signal and a second end configured to receive a second fiber pump signal such that the first fiber pump signal and the second fiber pump signal propagate within the optical gain fiber in a direction towards one another. An optical loss device is coupled to the optical gain fiber, wherein the optical loss device isolates a narrow line-width random fiber laser signal from a signal generated within the optical gain fiber.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: May 2, 2017
    Assignee: University of Ottawa
    Inventors: Zhonghua Ou, Xiaoyi Bao, Yang Li, Liang Chen
  • Patent number: 9512455
    Abstract: The present invention relates to the cell-based production of bacterial nonulosonates and their biosynthetic precursors. Specifically, the present invention provides recombinant cells for the production of pseudaminic acid, legionaminic acid, UDP-2,4-diacetamido-2,4,6-trideoxy-?-L-altropyranose, and UDP-2,4-diacetamido-2,4,6-trideoxy-?-D-glucopyranose. Methods for producing the sugars are also provided.
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: December 6, 2016
    Assignees: National Research Council of Canada, University of Ottawa
    Inventors: Christopher N. Boddy, Susan M. Logan, Benjamin R. Lundgren, Ian C. Schoenhofen, Dennis M. Whitfield
  • Patent number: 9500562
    Abstract: A Kerr medium is introduced into OFDR configuration to enable phase to power variation conversion thereby enabling an all-optical beat signal acquisition, thus eliminating performance limits associated with bandwidth capabilities of electronic and optoelectronic components.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: November 22, 2016
    Assignee: University of Ottawa
    Inventors: Chams Baker, Xiaoyi Bao
  • Patent number: 9496681
    Abstract: A method and apparatus is disclosed for generating tunable attosecond-scale radiation pulses, with a frequency in range of ultraviolet to soft-X-ray, from a solid-state medium. The invention utilizes an intense laser pulse to drive a high harmonic generation (HHG) process in a solid state medium and a weak secondary field to control the HHG process. The weak secondary field has a frequency equal to the second harmonic of the intense laser pulse. The spatial, temporal and spectral properties of the HHG process and the emitted harmonic beam are tuned by adjusting the relative delay between the two fields and the intensity of the weak secondary field.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: November 15, 2016
    Assignee: University of Ottawa
    Inventors: Giulio Vampa, Paul Corkum, Thomas Brabec
  • Patent number: 9462842
    Abstract: Safety head wear for use for example in high risk activities such as sports and industrial purposes where protection from head injuries is required. Components are provided inserted between the liner and outer shell and consists of two parts; a pod and a foam or foam like surrogate or structure. The foam or foam like material is contained in the chamber and is positioned in such a way to create constant force between the surface of the shell and head. The device provides a method of managing compression force characteristics of the helmet around the head designed to decrease brain trauma resulting from high linear acceleration during impacts to the helmet.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: October 11, 2016
    Assignee: University of Ottawa
    Inventors: Thomas Blaine Hoshizaki, Andrew Michael Post
  • Publication number: 20160210167
    Abstract: Technologies are generally provided to virtualize hardware acceleration. In some examples, a coprovisor component may be configured to multiplex multiple domains' requests to access a hardware accelerator such as a field programmable gate array (FPGA), an application specific integrated circuit (ASIC), or a comparable accelerator in a paravirtualized environment. Hyper-requesting may be employed for hardware acceleration virtualization, where a hardware acceleration module concurrently loads a portion of data of a request for a first accelerator application and a portion of data of another request for a second accelerator application and simultaneously processes the two portions of data. Directly situated on a device driver layer, the coprovisor may schedule portions of access requests to the hardware accelerator at the same time through direct memory access (DMA) context switching.
    Type: Application
    Filed: September 24, 2013
    Publication date: July 21, 2016
    Applicant: University of Ottawa
    Inventors: Miodrag Bolic, Jonathan Parri, Wei Wang
  • Patent number: 9397241
    Abstract: Apparatus and techniques are presented such as can be used for electro-optic modulation and detection or other applications. For example, an optical metal grating is disposed on a thin metal film to couple light from broadside to the metal film as surface plasmon-polariton waves; below the metal film is located a thin insulating layer and a doped semiconductor region forming a metal-insulator-semiconductor structure. The device can be configured to operate as a reflection or transmission modulator, or as a photodetector, for example. Modulating the voltage applied to the metal-insulator-semiconductor structure modulates the carrier concentration in the semiconductor near the insulating layer, which modulates the refractive index of the semiconductor in this region, thus modulating the coupling efficiency to the surface plasmon-polaritons, thus modulating the reflectance and transmittance of the device.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: July 19, 2016
    Assignee: University of Ottawa
    Inventors: Pierre Simon Joseph Berini, Chengkun Chen
  • Patent number: 9358262
    Abstract: A method of treating or preventing diabetes or obesity that comprises administering an antioxidant-enriched composition produced by fermenting fruit extracts with the bacteria Serratia vaccinii. The antioxidant-enriched composition is capable of decreasing plasma glucose levels, increasing circulating adiponectin levels and decreasing hyperphagia in a subject.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: June 7, 2016
    Assignee: University of Ottawa
    Inventors: Chantal Matar, Pierre S. Haddad
  • Patent number: 9356421
    Abstract: A method and apparatus for launching optical pump signals into a disordered gain medium at two points thereby producing a narrow line-width random fiber laser within the disordered gain medium. The optical pump signals are propagated in a direction through the disordered gain medium towards one another. The apparatus may comprise an optical gain fiber having a first end configured to receive a first fiber pump signal and a second end configured to receive a second fiber pump signal such that the first fiber pump signal and the second fiber pump signal propagate within the optical gain fiber in a direction towards one another. An optical loss device is coupled to the optical gain fiber, wherein the optical loss device isolates a narrow line-width random fiber laser signal from a signal generated within the optical gain fiber.
    Type: Grant
    Filed: October 15, 2014
    Date of Patent: May 31, 2016
    Assignee: University of Ottawa
    Inventors: Zhonghua Ou, Xiaoyi Bao, Yang Li, Liang Chen
  • Patent number: 9276373
    Abstract: A high-finesse Fabry-Perot interferometer (FPI) is introduced into a coherent Brillouin RFL configuration to thereby produce a frequency stabilized random laser.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: March 1, 2016
    Assignee: University of Ottawa
    Inventors: Meng Pang, Xiaoyi Bao, Liang Chen, Zengguang Qin, Yang Lu, Ping Lu
  • Patent number: 9252555
    Abstract: A method and apparatus for producing single mode random fiber ring laser by inducing random distributed feedback in a short section of the fiber ring to thereby enable single mode lasing while reducing frequency jitter and relative intensity noise. The random distributed feedback maybe achieved through deep refractive index modulation at a series of randomly distributed laser-irradiated points inscribed along the length of the induced random distributed feedback fiber. The laser-processed random distributed feedback fiber maybe incorporated into the fiber ring in conjunction with a variable optical attenuator and band pass optical filter for enhancing the single mode operation.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: February 2, 2016
    Assignee: University of Ottawa
    Inventors: Yang Li, Ping Lu, Xiaoyi Bao, Zhonghua Ou
  • Patent number: 9162991
    Abstract: A compound of Formula I or Formula II:
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: October 20, 2015
    Assignee: University of Ottawa
    Inventors: Christophe Pardin, Jeffrey W. Keillor, William D. Lubell