Abstract: Parkinson's Disease in animals is treated by administering to the animal 3-ethyl-aminodamantane in a pharmaceutically acceptable carrier.

Abstract: Apparatus is described for detecting air disturbances created by low level wind shear. The apparatus includes optics for directing infrared radiation towards a continuously rotating chopper wheel having a plurality of infrared filters which have effectively different distance sensitivities and therefrom to a radiation sensor which produces an analog output signal that is demodulated by a synchronous demodulator. The demodulated signal is then routed through a gated integrator to a selective multiplexing circuit which has a plurality of output channels and is controlled by an electronic detector connected with the chopper wheel. Each channel includes a low pass filter and the outputs therefrom are coupled to a signal processor which thus receives periodically updated information to provide a display indicative of sensed air disturbances due to low level wind shear.

Abstract: Fraction I protein from plant leaves is purified and subsequently crystallized. The crystallization methods disclosed herein unexpectedly produce crystallization in all crop leaves examined, although for some species modification by salt addition is required to achieve crystallization and to prevent formation of substantial percentages of amorphous protein precipitates. It has been found that a fraction I protein solution, when mixed with a precipitant solution having a pH generally within the range of 4.8-7.2, in an amount and at a pH sufficient to provide a mixed solution (protein solution mixed with precipitant solution) having a final pH in the range of 6.6-7.0, causes crystallization of fraction I protein from plant leaves, provided that the precipitant solution is at a pH lower than the pH of the protein solution. Optimum results have been obtained when the pH of the precipitant solution is in the range of 5.0 to 6.0 and the protein solution in the range of 7.0 to 7.5.

Abstract: Stable aqueous solutions for substantially non-inflammatory, non-immunogenic parenteral administration to domesticated animals, especially livestock animals, comprising water-soluble organometallic complexes of ions of zinc, copper, manganese, chromium and selenium and including at least two organic, metal-ion-complexing agents. Stable solutions further including soluble organometallic complexes of iron and cobalt. Methods for restoring and/or maintaining normal micromineral-dependent metabolic function, increasing feed intake, increasing vigor, and facilitating resistance to infectious disease comprising administering such solutions to domesticated animals.

Abstract: The reticulocyte content present in a specimen of red blood cells is quantitatively measured based upon the selective immunoreactivity of the reticulocyte portion of the specimen with a reticulocyte-specific antibody which is immunoreactive with proteinaceous material associated with reticulocytes but not associated with mature red blood cells. Such immunoreactive proteinaceous material may be transferrin, transferrin receptor, transcobalamin II, or transcobalamin II receptor. Various procedures are described for quantitating such selective immunoreactivity, including fluorescent and radioactive detection techniques employing direct or indirect fluorescent or radioactive labeling of the reticulocyte-specific antibody.

Abstract: An esophageal cardiac pulse probe includes a lumen for insertion into the esophagus, the end of the lumen preferably being closed by a flexible diaphragm. Pressure variations imparted to the fluid within the lumen in response to sounds from the heart and the lungs are transmitted to an electrical transducer which produces an electrical signal proportional to the time-varying frequency and intensity of the pressure variations. This signal is selectively filtered to effectively eliminate signal components due to respiratory noise and audible heart sounds and the resulting signal is fed to an appropriate visual display apparatus. Direct acoustic cardiac sound monitoring is also achievable with an earpiece connected to the lumen. Several probe geometries and a method of cardiac pulse waveform monitoring are also disclosed.

Abstract: The disclosure is directed to an apparatus and method for generating a two-dimensional back-projected image of a slice of an object, and also to an optical filtering apparatus and method which, inter alia, is useful therein. Successive beams of light are generated, each having a narrow elongated cross-section with an optical intensity that is a function of the density characteristic of the slice of the object as measured at a particular relative rotational angle. The beams are optically filtered and spread in a direction transverse to their length. Optical filtering with a filter function having both positive and negative components is preferably performed using a single-channel time modulated technique. A television camera receives the spread filtered beams. Relative rotation is effected between the beams and the camera, the rotation being related to the relative rotational angles of the object associated with the generation of the successive beams of light.

Abstract: The disclosure is directed to an apparatus and method for generating a two-dimensional back-projected image of a slice of an object, and also to an optical filtering apparatus and method which, inter alia, is useful therein. Successive beams of light are generated, each having a narrow elongated cross-section with an optical intensity that is a function of the density characteristic of the slice of the object as measured at a particular relative rotational angle. The beams are optically filtered and spread in a direction transverse to their length. Optical filtering with a filter function having both positive and negative components is preferably performed using a single-channel time modulated technique. A television camera receives the spread filtered beams. Relative rotation is effected between the beams and the camera, the rotation being related to the relative rotational angles of the object associated with the generation of the successive beams of light.

Abstract: Anti human chorionic gonadotropin (anti-hCG) and/or anti human chorionic gonadotropin- beta subunit (anti-hCG-.beta.) labeled with Technetium-99M are/is administered to a human. The biodistribution of the labeled composition is monitored in order to determine whether the labeled composition accumulates at cancer sites, e.g. tumors that produce human chorionic gonadotropin (hCG), human chorionic gonadotropin-like material, and a compound similar to and/or identical to the beta-chain of chorionic gonadotropin, or mixtures thereof which would bind specifically to anti-hCG and/or anti-hCG-.beta..

Abstract: A non-invasive birth control device in the form of a custom-formed, valved cervical cap is disclosed. The cervical cap comprises a cup-shaped elastomeric shell substantially complementary with contiguous surface of portio vaginalis cervicis when in contact therewith and having an aperture at the apex of the shell. The aperture is covered by an elastomeric web secured to the shell and defines, together with the shell, a one-way valve means having a discharge port offset from the aperture. The cervical cap can be fabricated from a specially designed blank of a thermoplastic elastomeric material using a replica of cervix uteri as a mold.

Abstract: Conjugated polymers are doped with dopant ions to a preselected room temperature electrical conductivity ranging from that characteristic of semiconductor behavior to that characteristic of metallic behavior, by means of an electrochemical procedure wherein the polymer is employed as one or both of the electrodes of an electrolytic cell, including as the electrolyte a compound which is ionizable into the dopant ions. Upon electrolysis of the electrolyte, the polymer, if used as the anode, becomes doped with anionic dopant ions to a p-type material; or if used as the cathode, becomes doped with cationic dopant ions to an n-type material.The above-described electrochemical doping procedure finds particularly useful application in the charging of novel secondary batteries in which a doped conjugated polymer is employed as one or both of the electrodes. Such secondary batteries, in their charged state, comprise a metal whose Pauling electronegativity value is no greater than 1.

Abstract: Antibody to anti human chorionic gonadotropin and/or antibody to anti human chorionic gonadotropin-beta subunit labeled with technetium-99m, iodine-123, iodine-125 or iodine-131 are/is administered to a human after the human has been administered anti-hCG and/or anti-hCG beta. The biodistribution of the labeled composition accumulates at cancer sites, e.g. tumors that produce human chorionic gonadotropin (hCG), human chorionic gonadotripin-like material, and a compound similar to and/or identical to the beta-chain of chorionic gonadotropin, or mixtures thereof which would bind specifically to anti-hCG and/or anti-hCG-beta.

Abstract: A new method for labeling proteins with 99m-technetium: (1) Start with any volume of technetium (pertechnetate and saline) solution and add 0.1 ml of stannous solution (stannous fluoride-acetate solution) per 15-20 ml of saline. The stannous ions will reduce the pertechnetate to technetium IV. (2) Pour the solution onto a sterile Sephadex G-25 column, The reduced technetium (Tc-IV) will bind to the very top layer of Sephadex. (3) Wash the column with saline solution to remove any free pertechnetate or unusual species of technetium. (4) Add the protein in the minimum volume of water to the top of the Sephadex column. Wait 30 minutes. During this waiting period ligand exchange will occur and the technetium will become bound to the protein, but only to those sites on the protein that form a stronger ligand bond than the Sephadex. This means that the only product that will be formed will be technetium strongly bound to proteins.

Abstract: A battery is provided in which the anode contains an alkali metal in a high state of thermodynamic activity; the cathode comprises a partially alkali metal-intercalated chalcogenide of the formula A.sub.y MZ.sub.x wherein A is an alkali metal more electropositive and larger than the anode alkali metal, M is a transition metal of Group IV or V, x is a numerical value of from about 1.8 to about 2.1, y is a numerical value of from about 0.01 to about 1 and Z is sulfur, selenium or tellurium; and the electrolyte comprises ions of the anode metal in a medium which is compatible with the anode and cathode allowing transport of the ion from anode to intercalate into the cathode.In the discharged state the battery includes a cathode characterized by the presence of A'.sub.z A.sub.y MZ.sub.x in which A' is alkali metal more electronegative than A and z is a numerical value in the range 0<z.ltoreq.3.25.

Abstract: Methods and materials for diagnosis of a multiple sclerosis disease state. Antigenic blood fractions from patients clinically diagnosed for multiple sclerosis are employed to generate heterologous species antibodies. Novel antibody preparations are employed to detect the presence or absence, in a blood sample of a patient to be tested, of immunologically significant components specifically associated with a multiple sclerosis disease state.

Abstract: Estrogen receptor protein, estrophilin, in a tissue sample is detected and quantified by radiochemical methods involving selective binding of the protein to controlled pore glass beads. Also disclosed are methods for selectively removing undesirable degradation products from radiochemically labelled non-polar steroid reagents, especially estradiol.

Abstract: A battery is provided in which the anode contains an alkali metal in a high state of thermodynamic activity; the cathode comprises a partially alkali metal-intercalated chalcogenide of the formula A.sub.y MZ.sub.x wherein A is an alkali metal more electropositive and larger than the anode alkali metal, M is a transition metal of Group IV or V, x is a numerical value of from about 1.8 to about 2.1, y is a numerical value of from about 0.01 to about 1 and Z is sulfur, selenium or tellurium; and the electrolyte comprises ions of the anode metal in a medium which is compatible with the anode and cathode allowing transport of the ion from anode to intercalate into the cathode.In the discharged state the battery includes a cathode characterized by the presence of A'.sub.z A.sub.y MZ.sub.x in which A' is alkali metal more electronegative than A and z is a numerical value in the range 0<z.ltoreq.3.25.

Abstract: A process for separating metal values from sea nodules by sulfating the nodule ore under substantially dry conditions, followed by leaching of the sulfated ore; separation of the leaching solution from water-insoluble residue and recovery of the metal values from the leaching solution.

Abstract: Electrochemical method and associated apparatus permit carbonaceous materials to be gasified to carbon oxides under mild conditions with the attendant formation of fuels or high energy intermediates such as hydrogen, or light hydrocarbons and production of electric power.

Abstract: It has been determined that ingested vitamin B.sub.12 is bound by R protein in gastric juice, but that it is not capable of absorption in this form. In a system with a normally functioning exocrine pancreas, R protein is degraded by pancreatic proteases in the small intestine, which then allows the B.sub.12 to be transferred and bound to intrinsic factor protein (IF) from which it can be absorbed. This phenomenon serves as the basis for a test for pancreatic exocrine function in which the following compositions are ingested: (1) a complex of IF and B.sub.12 in which the B.sub.12 is labelled; (2) a combination of another binding material, such as R protein, and B.sub.12, in which the B.sub.12 is labelled (in preferred embodiments the B.sub.12 is labelled differently than the B.sub.12 in the IF-B.sub.12 complex); and (3) means for preventing R protein in the gastric juices from removing B.sub.12 from the IF-B.sub.12 complex, (in preferred embodiments such means are B.sub.