Abstract: Described are the compounds, compositions and methods of treating diseases and disorders characterized by Formyl Peptide Receptor 1 (FPR1) or FPR2 activity.

Abstract: Described are methods for treating diseases and disorders characterized by Formyl Peptide Receptor 1 (FPR1) or FPR2 activity.

Abstract: A printing head assembly for 3D printing and methods of using the same are provided. The printing head incorporates a backing means that can be shaped and positioned by use of an attractive force. This creates the possibility of embodiments in which the head can move in three dimensions, without the need to print each successive layer on the layer below. Methods of ensuring the security and integrity of the 3D printing process are also provided.

Abstract: The disclosure provides chemical compounds possessing therapeutic and/or protective properties against oxidative damage. Methods of making such therapeutic and/or protective compounds and associated compositions are also provided, as are methods for their use, which include protecting cells from oxidative damage and/or inhibiting production of ROS in a cell or subject, as well as preventing or reducing the extent of tissue damage caused by an ischemic event in a subject at elevated risk of such an event.

Abstract: A method of encapsulating an engineered pellet in a porous membrane is disclosed. The method includes the steps of: (i) dissolving a membrane solute in a membrane solvent to produce a membrane solution; (ii) applying the membrane solution to a pellet to form a pellet encapsulated with the membrane solution; (iii) subjecting the membrane solution that encapsulates the pellet to a phase inversion and; (iv) drying the pellet to form a porous membrane encapsulated pellet. A porous membrane encapsulated pellet is also described.

Abstract: The present disclosure generally pertains to methods of treating myocardial infarct involving administering a platelet anti-aggregate, a cysteine-aspartic protease inhibitor, and reperfusion therapy. In certain embodiments, the platelet anti-aggregate is at least one P2Y12 receptor antagonist or Glycoprotein IIb/IIIa inhibitor, the cysteine-aspartic protease inhibitor is selected from the group consisting of Caspase-1, 4, 5, 11 and 12 inhibitors, and reperfusion therapy is percutaneous coronary intervention. In certain embodiments, the at least one P2Y12 receptor antagonist is selected from the group consisting of cangrelor, ticagrelor, clopidogrel and prasugrel. The disclosed methods provide an improved cardioprotective effect against infarction when compared with the current standard of care.

Abstract: A printing head assembly for 3D printing and methods of using the same are provided. The printing head incorporates a backing means that can be shaped and positioned by use of an attractive force. This creates the possibility of embodiments in which the head can move in three dimensions, without the need to print each successive layer on the layer below. Methods of ensuring the security and integrity of the 3D printing process are also provided.

Abstract: A printing head assembly for 3D printing and methods of using the same are provided. The printing head incorporates a backing means that can be shaped and positioned by use of an attractive force. This creates the possibility of embodiments in which the head can move in three dimensions, without the need to print each successive layer on the layer below. Methods of ensuring the security and integrity of the 3D printing process are also provided.

Abstract: A single-use foldable stool specimen collection device supportable atop the top face of a toilet seat is described. The device includes (a) a U-shaped foldable support member having a top surface, a bottom surface, an exterior U-shaped edge and an interior U-shaped edge defining a stool collection aperture; and (b) a foldable stool collection pocket attached to said foldable support member along its bottom surface, wherein the collection pocket spans and extends below the stool collection aperture. A folded stool specimen collection device and a stool specimen collecting system are also disclosed.

Abstract: A new born temperature and heart monitor wrap apparatus and method includes a wrap where the wrap is configured such that a new born is substantially covered by the wrap when the wrap is applied to the new born. A heart monitor device is attached to the wrap and a temperature lead retainer is attached to the wrap. A substrate is provided where the wrap is removably connected to the substrate.

Abstract: The disclosure provides chemical compounds possessing therapeutic and/or protective properties against oxidative damage. Methods of making such therapeutic and/or protective compounds and associated compositions are also provided, as are methods for their use, which include protecting cells from oxidative damage and/or inhibiting production of ROS in a cell or subject, as well as preventing or reducing the extent of tissue damage caused by an ischemic event in a subject at elevated risk of such an event.

Abstract: An improved skin blood flow measurement apparatus consists of a chassis with an antenna connected with the chassis such that the antenna directs RF energy at an area of a skin surface below the chassis. A temperature sensor is also connected with the chassis such that the temperature sensor is held in fixed relation to the antenna and such that the temperature sensor is also directed to the same said area of a skin surface below the chassis for measurement of temperature of the area and further where the temperature sensor does not contact the skin surface and where the chassis supports the antenna and the temperature sensor in fixed relation to the area.

Abstract: Processes for chemical functionalization of materials are described. The processes generally include chemical reaction between a thiol group of a first compound or material and an alkene group or alkyne group of a second compound or material. Also disclosed are functionalized materials and compounds suitable for functionalizing a material.

Abstract: Useful, accessible, and predictive biomarkers for discriminating between ovarian cancer and benign adnexal masses are provided. Specifically, peptide biomarkers present in bodily fluid samples such as cervical-vaginal fluid (CVF) have been identified as having particularly robust diagnostic for identifying whether ovarian masses such as adnexal masses are benign, and ruling our ovarian cancer. The biomarker peptides disclosed herein therefore provide significantly enhanced sensitivity and specificity levels relative to extant methods for distinguishing benign ovarian masses from ovarian cancers. The biomarkers provide a timely and cost-efficient diagnostic capable of being used in a selection process to identify patients for whom treatment, which may include surgical resection and/or monitoring, may be performed by an obstetric gynecologist rather than a gynecologic oncologist.

Abstract: Processes for chemical functionalization of materials is described. The processed generally include chemical reaction between a thiol group of a first compound or material and an alkane group or alkyne group of a second compound or material. Also disclosed are functionalized materials and compounds suitable for functionalizing a material.

Abstract: Disclosed are genetic delivery systems that utilize genetic elements of the piggyBac family transposon system, and methods of introducing nucleic acid into target cells using the genetic delivery systems.

Abstract: The disclosure provides chemical compounds possessing therapeutic and/or protective properties against oxidative damage. Methods of making such therapeutic and/or protective compounds and associated compositions are also provided, as are methods for their use, which include protecting cells from oxidative damage and/or inhibiting production of ROS in a cell or subject, as well as preventing or reducing the extent of tissue damage caused by an ischemic event in a subject at elevated risk of such an event.

Abstract: Systems and methods for visually displaying instances of increased susceptibility for commission of medical errors are provided. Execution of programming instructions on a computer-readable medium causes a processor to retrieve historical workload data corresponding to environmental conditions experienced by and near misses associated with an individual or team of individuals during a first period of time from one or more data repositories. Retrieved workload data is processed to establish threshold limits for distinct working conditions represented within the workload data for the individual or team of individuals. Workload data corresponding to a second period of time is retrieved for the individual or team of individuals and compared to established threshold limits by the processor. Based on the comparison, the processor generates one or more displayable indicia indicative of the individual's or team of individuals' risk of committing a medical error due to an experienced workload.

Abstract: Processes for chemical functionalization of materials is described. The processed generally include chemical reaction between a thiol group of a first compound or material and an alkane group or alkyne group of a second compound or material. Also disclosed are functionalized materials and compounds suitable for functionalizing a material.

Abstract: Systems and methods for visually displaying instances of increased susceptibility for commission of medical errors are provided. Execution of programming instructions on a computer-readable medium causes a processor to retrieve historical workload data corresponding to environmental conditions experienced by and near misses associated with an individual or team of individuals during a first period of time from one or more data repositories. Retrieved workload data is processed to establish threshold limits for distinct working conditions represented within the workload data for the individual or team of individuals. Workload data corresponding to a second period of time is retrieved for the individual or team of individuals and compared to established threshold limits by the processor. Based on the comparison, the processor generates one or more displayable indicia indicative of the individual's or team of individuals' risk of committing a medical error due to an experienced workload.