Abstract: In one embodiment, a method for projecting images on a subject includes determining a pose and position of the subject, adjusting a three-dimensional model of an anatomical structure of the subject to match the determined pose and position, and projecting an image of the anatomical structure onto the subject in registration with the actual anatomical structure of the subject to illustrate the location of the structure on or within the subject.

Abstract: The disclosure provides compositions that are useful for eliciting a strain-transcending immune response in an animal or human directed against the blood-stage of the malarial parasite Plasmodium vivax. The compositions are based on the ligand domain of Plasmodium vivax Duffy binding protein (PvDBPII). Polar charged polymorphic residues within the dominant strain-specific B-cell epitope were mutated to uncharged residues (e.g. serine, alanine and threonine). This DEKnull variant of PvDBPII produced in bacteria can be purified and refolded in vitro to mimic conformation and erythrocyte binding function of native DBPII. Immunogenicity of DEKnull was confirmed by administration to mice. Compared to the naturally-occurring, strain variant DBPII, DEKnull elicits antibodies that are more broadly reactive with different strain variants of DBPII and enhances production of functional inhibitory antibodies to the shared protective epitopes of native DBPII.

Abstract: In one embodiment, a variable screen includes a generally flat sheet having a front surface, a back surface, and a plurality of elongated slits that extend through the sheet from the front surface to the back surface, wherein the sheet includes a shape memory material that enables the slits to open into openings through which light and fluid can pass when a tensile force is applied to the sheet in a direction generally perpendicular to the slits and further enables the slits and openings to automatically when the tensile force is removed.