Patents Assigned to University of Toledo
  • Patent number: 7994279
    Abstract: Modified GAD65 compositions antagonize the activities of islet-specific T cells that contribute to the progression of one or more autoimmune disorders. The compositions are also antagonistic in humanized mice that express human HLA alleles associated with increased-risk of Type 1 diabetes.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: August 9, 2011
    Assignee: The University of Toledo
    Inventor: Anthony Quinn
  • Patent number: 7957609
    Abstract: The present invention provides a method and a system for producing an image using an imaging system by weighting: i) the signals transmitted from at least one element of a transducer array to form limited diffraction transmitted beams or the transmitted beams are steered with linear time delay over transducer aperture; and, ii) weighting the echo signals received at the separate elements to form limited diffraction receive beams or doing Fourier transformations of the echo signals over the transducer aperture. Fourier transformations of the weighted or Fourier transformed signals form multi-dimensional k-space data sets which are used to interpolate into a rectilinear k-space of the object to be imaged. Inverse Fourier transformation along each dimension of the rectilinear k-space to produce an image.
    Type: Grant
    Filed: August 29, 2006
    Date of Patent: June 7, 2011
    Assignee: The University of Toledo
    Inventors: Jian-yu Lu, Jiqi Cheng
  • Patent number: 7893268
    Abstract: Epothilone analogues include a molecular scaffold which holds at least one segment of epothilone in a predetermined orientation and which rigidities a region between the macrolactone ring and the aromatic side-chain.
    Type: Grant
    Filed: July 20, 2006
    Date of Patent: February 22, 2011
    Assignee: University of Toledo
    Inventors: Viranga Tillekeratne, Richard D. Hudson, Mamoun Alhamadsheh
  • Patent number: 7879644
    Abstract: A novel photovoltaic solar cell and method of making the same are disclosed. The solar cell includes: at least one absorber layer which could either be a lightly doped layer or an undoped layer, and at least a doped window-layers which comprise at least two sub-window-layers. The first sub-window-layer, which is next to the absorber-layer, is deposited to form desirable junction with the absorber-layer. The second sub-window-layer, which is next to the first sub-window-layer, but not in direct contact with the absorber-layer, is deposited in order to have transmission higher than the first-sub-window-layer.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: February 1, 2011
    Assignee: The University of Toledo
    Inventors: Xunming Deng, Xianbo Liao, Wenhui Du
  • Publication number: 20100324094
    Abstract: A method for synthesizing anti-leukemic epothilone analogues includes rigidifying a region between the macrolactone ring and the aromatic side-chain. The anti-leukemic compositions are non-naturally occurring epothilone analogue that are rigidified between the macrolactone ring and the aromatic side-chain.
    Type: Application
    Filed: March 20, 2008
    Publication date: December 23, 2010
    Applicant: The University of Toledo
    Inventors: Viranga Tillekeratne, Richard A. Hudson, Mamoun Alhamadsheh
  • Patent number: 7750234
    Abstract: An integrated photoelectrochemical (PEC) cell generates hydrogen and oxygen from water while being illuminated with radiation. The PEC cell employs a liquid electrolyte, a multi-junction photovoltaic electrode, and a thin ion-exchange membrane. A PEC system and a method of making such PEC cell and PEC system are also disclosed.
    Type: Grant
    Filed: May 23, 2005
    Date of Patent: July 6, 2010
    Assignee: The University Of Toledo
    Inventors: Xunming Deng, Liwei Xu
  • Patent number: 7695415
    Abstract: This trunk rotation device uses dynamic movement of one's body such as, shoulder, hip, knee, back, thigh, and abdominal musculature. The device provides a method for exercising the spinal column and the muscles of the torso, including those in the abdominal lumbar and thoracic regions involving rotational torque. In a preferred embodiment, the device is a golf exercise and flexibility apparatus. The golf exercise apparatus provides resistance to a golfer during a golf swing to strengthen and condition the muscles of the axial skeleton of the golfer in a functional posture.
    Type: Grant
    Filed: August 9, 2005
    Date of Patent: April 13, 2010
    Assignees: University of Toledo, The Turning Point LLC
    Inventors: Vijay K. Goel, Danny M. Pincivero, David Dick, John Jaegly, F. Alan Schultheis, Kathleen Herndon
  • Patent number: 7674608
    Abstract: Dissolution, partial dissolution or softening of cellulose in an ionic liquid (IL) and its subsequent contact with anti-solvent produces regenerated cellulose more amorphous in structure than native cellulose, which can be separated from the IL/anti-solvent mixture by mechanical means such as simple filtration or centrifugation. This altered morphology of IL-treated cellulose allows a greater number of sites for enzyme adsorption with a subsequent enhancement of its saccharification. The IL-treated cellulose exhibits significantly improved hydrolysis kinetics with optically transparent solutions formed after about two hours of reaction. This provides an opportunity for separation of products from the catalyst (enzyme) easing enzyme recovery. With an appropriate selection of enzymes, initial hydrolysis rates for IL-treated cellulose were up to two orders of magnitude greater than those of untreated cellulose.
    Type: Grant
    Filed: February 23, 2007
    Date of Patent: March 9, 2010
    Assignee: The University of Toledo
    Inventors: Sasidhar Varanasi, Constance Ann Schall, Anantharam Prasad Dadi
  • Patent number: 7667418
    Abstract: A control system for an electromagnetic rotary drive for bearingless motor-generators comprises a winding configuration comprising a plurality of individual pole pairs through which phase current flows, each phase current producing both a lateral force and a torque. A motor-generator comprises a stator, a rotor supported for movement relative to the stator, and a control system. The motor-generator comprises a winding configuration supported by the stator. The winding configuration comprises at least three pole pairs through which phase current flows resulting in three three-phase systems. Each phase system has a first rotor reference frame axis current that produces a levitating force with no average torque and a second rotor reference frame axis current that produces torque.
    Type: Grant
    Filed: October 30, 2008
    Date of Patent: February 23, 2010
    Assignee: The University of Toledo
    Inventors: Peter E. Kascak, Ralph H. Jansen, Timothy P. Dever
  • Patent number: 7667133
    Abstract: A novel photovoltaic solar cell and method of making the same are disclosed. The solar cell includes: at least one absorber layer which could either be a lightly doped layer or an undoped layer, and at least a doped window-layers which comprise at least two sub-window-layers. The first sub-window-layer, which is next to the absorber-layer, is deposited to form desirable junction with the absorber-layer. The second sub-window-layer, which is next to the first sub-window-layer, but not in direct contact with the absorber-layer, is deposited in order to have transmission higher than the first-sub-window-layer.
    Type: Grant
    Filed: October 29, 2003
    Date of Patent: February 23, 2010
    Assignee: The University of Toledo
    Inventor: Xunming Deng
  • Patent number: 7667438
    Abstract: An energy storage system for a vehicle includes an ultracapacitor that is electrically coupled in parallel with a battery through a diode connected in series with the battery. The ultracapacitor delivers the energy required for all high current surges that occur during engine start, acceleration, and regeneration. The battery is used only to assist with longer duration, high energy loads, such as accessory loads when an engine of the vehicle is not running. In other words, the battery conducts only during longer and less-frequent pulses and, therefore, does not have to withstand high-power pulses.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: February 23, 2010
    Assignees: Chrysler Group LLC, University of Toledo
    Inventors: Cyrus N Ashtiani, Thomas A Stuart
  • Publication number: 20090305340
    Abstract: Modified GAD65 compositions antagonize the activities of islet-specific T cells that contribute to the progression of one or more autoimmune disorders. The compositions are also antagonistic in humanized mice that express human HLA alleles associated with increased-risk of Type 1 diabetes.
    Type: Application
    Filed: March 30, 2007
    Publication date: December 10, 2009
    Applicant: University of Toledo
    Inventor: Anthony Quinn
  • Publication number: 20090226923
    Abstract: The present invention is directed to methods and compositions for evaluating nucleic acids, methods of preparing such compositions, and applications and business methods employing such compositions and methods. In particular, the present invention provides business methods for operating a gene expression measurement service.
    Type: Application
    Filed: March 16, 2009
    Publication date: September 10, 2009
    Applicants: University of Toledo, Gene Express, Inc.
    Inventors: James C. Willey, Brad Austermiller, Erin L. Crawford, Charles Knight, Terry Osborn, Robert Zahorchak
  • Patent number: 7547548
    Abstract: The present invention relates to a method of reprogramming plant development that allows flower buds and seeds to arise de novo, directly from a cotyledon or radicle explants or from shoots produced on a cotyledon or radicle. The present invention also provides for an improved culturing media that provide for in vitro flowering.
    Type: Grant
    Filed: May 27, 2005
    Date of Patent: June 16, 2009
    Assignee: University of Toledo
    Inventors: Sairam V. Rudrabhatla, Stephen L. Goldman
  • Publication number: 20090055968
    Abstract: The present invention relates to a method of reprogramming plant development that allows flower buds and seeds to arise de novo, directly from a cotyledon or radicle explants or from shoots produced on a cotyledon or radicle. The present invention also provides for an improved culturing media that provide for in vitro flowering.
    Type: Application
    Filed: October 17, 2008
    Publication date: February 26, 2009
    Applicant: University Of Toledo, A University Instrumentally Of The State Of Ohio
    Inventors: Sairam V. Rudrabhatla, Stephen L. Goldman
  • Patent number: 7456537
    Abstract: A control system for an electromagnetic rotary drive for bearingless motor-generators comprises a winding configuration comprising a plurality of individual pole pairs through which phase current flows, each phase current producing both a lateral force and a torque. A motor-generator comprises a stator, a rotor supported for movement relative to the stator, and a control system. The motor-generator comprises a winding configuration supported by the stator. The winding configuration comprises at least three pole pairs through which phase current flows resulting in three three-phase systems. Each phase system has a first rotor reference frame axis current that produces a levitating force with no average torque and a second rotor reference frame axis current that produces torque.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: November 25, 2008
    Assignee: The University of Toledo
    Inventors: Peter E. Kascak, Ralph H. Jansen, Timothy P. Dever
  • Patent number: 7417407
    Abstract: A circuit for charging a battery combined with a capacitor includes a power supply adapted to be connected to the capacitor, and the battery. The circuit includes an electronic switch connected to the power supply. The electronic switch is responsive to switch between a conducting state to allow current and a non-conducting state to prevent current flow. The circuit includes a control device connected to the switch and is operable to generate a control signal to continuously switch the electronic switch between the conducting and non-conducting states to charge the battery.
    Type: Grant
    Filed: October 12, 2005
    Date of Patent: August 26, 2008
    Assignee: The University of Toledo
    Inventors: Thomas A. Stuart, Cyrus N. Ashtiani
  • Publication number: 20080166833
    Abstract: A novel photovoltaic solar cell and method of making the same are disclosed. The solar cell includes: at least one absorber layer which could either be a lightly doped layer or an undoped layer, and at least a doped window-layers which comprise at least two sub-window-layers. The first sub-window-layer, which is next to the absorber-layer, is deposited to form desirable junction with the absorber-layer. The second sub-window-layer, which is next to the first sub-window-layer, but not in direct contact with the absorber-layer, is deposited in order to have transmission higher than the first-sub-window-layer.
    Type: Application
    Filed: September 7, 2007
    Publication date: July 10, 2008
    Applicant: University of Toledo
    Inventor: Xunming Deng
  • Publication number: 20080073205
    Abstract: A photovoltaic electrolysis (IPE) cell has a photovoltaic component and an electrolysis component which integrated, through an interconnect design, into a single unit.
    Type: Application
    Filed: October 11, 2007
    Publication date: March 27, 2008
    Applicants: University of Toledo, MWOE. Inc.
    Inventors: Mahabala Adiga, Xunming Deng, Aarohi Vijh, Liwei Xu
  • Patent number: D641691
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: July 19, 2011
    Assignee: University of Toledo
    Inventor: Xunming Deng