Patents Assigned to University of Wollongong
  • Patent number: 11850449
    Abstract: An irradiation method and system for irradiating a target volume, the method comprising: providing thermal neutron absorbing nuclides (such as in the form of a high neutron cross-section agent) at the target volume; and producing neutrons by irradiating nuclei in or adjacent to the target volume with a beam of particles consisting of any one or more of protons, deuterons, tritons and heavy ions, thereby prompting production of the neutrons through non-elastic collisions between the atoms in the path of the beam (including the target) and the particles. The neutron absorbing nuclides absorb neutrons produced in the non-elastic collisions, thereby producing capture products or fragments that irradiate the target volume.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: December 26, 2023
    Assignees: Australian Nuclear Science and Technology Organisation, University of Wollongong
    Inventors: Mitra Safavi-Naeini, Andrew Stephen Chacon
  • Patent number: 11819489
    Abstract: An anti-cancer agent is provided comprising a tumour homing peptide having, or having been modified to present, two cysteine residues, with an arsenic atom between, such that the tumour homing peptide cyclises to give an arsenic-containing anti-cancer agent. This allows for selection of an appropriate tumour homing peptide for treatment of a given cancer whereby the subsequent agent provides for a more targeted delivery of arsenic to the tumour microenvironment.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: November 21, 2023
    Assignee: University of Wollongong
    Inventors: Carolyn Therese Dillon, Judith Anne Carrall
  • Patent number: 11311720
    Abstract: The present disclosure provides methods of making and applying metallized graphene fibers in bioelectronics applications. For example, platinized graphene fibers may be used as an implantable conductive suture for neural and neuro-muscular interfaces in chronic applications. In some embodiments, an implantable electrode includes a multi-layer graphene-fiber core, an insulative coating surrounding the multi-layer graphene-fiber core, and a metal layer disposed between the multi-layer graphene-fiber core and the insulative coating.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: April 26, 2022
    Assignees: University of Wollongong, Board of Regents, The University of Texas System
    Inventors: Mario Romero-Ortega, Gordon Wallace, Maria Gonzalez Gonzalez, Rouhollah Ali Jalili
  • Publication number: 20200155834
    Abstract: The present disclosure provides methods of making and applying metallized graphene fibers in bioelectronics applications. For example, platinized graphene fibers may be used as an implantable conductive suture for neural and neuro-muscular interfaces in chronic applications. In some embodiments, an implantable electrode includes a multi-layer graphene-fiber core, an insulative coating surrounding the multi-layer graphene-fiber core, and a metal layer disposed between the multi-layer graphene-fiber core and the insulative coating.
    Type: Application
    Filed: November 21, 2019
    Publication date: May 21, 2020
    Applicants: Board of Regents, The University of Texas System, University of Wollongong
    Inventors: Mario ROMERO-ORTEGA, Gordon Wallace, Maria Gonzalez Gonzalez, Rouhollah Ali Jalili
  • Publication number: 20180140693
    Abstract: Isolated proteins and immunogenic fragments thereof, for use in the treatment and prevention of a Group A Streptococcus infection are provided. In particular, the invention provides pharmaceutical compositions and methods of prophylactic and/or therapeutic treatment of a Group A Streptococcus infection.
    Type: Application
    Filed: January 5, 2018
    Publication date: May 24, 2018
    Applicant: University of Wollongong
    Inventors: Mark Walker, Jason Cole, Anna Henningham
  • Patent number: 9156855
    Abstract: The present invention relates generally to methods and compounds for regulating the release of nitric oxide in the vicinity of biofilm-forming microorganisms to regulate programmed cell death in the microorganisms and thereby promote dispersal of microorganism from biofilms and/or inhibit biofilm formation or development. More particularly, the invention relates to the use of compounds to provide spatial and temporal control over nitric oxide release.
    Type: Grant
    Filed: May 16, 2012
    Date of Patent: October 13, 2015
    Assignees: Newsouth Innovation Pty Limited, University of Wollongong
    Inventors: Nicolas Barraud, Bharat Gangadhar Kardak, Michael John Kelso, Staffan Kjelleberg, Scott Rice
  • Patent number: 9140810
    Abstract: A proton computed tomography (pCT) detector system, including two tracking detectors in sequence on a first side of an object to be imaged, two tracking detectors in sequence on an opposite side of the object to be imaged, a calorimeter, and a computer cluster, wherein the tracking detectors include plastic scintillation fibers. All fibers in the detector system are read out by Silicon Photomultipliers (SiPM). A method of imaging an object by emitting protons from a source through two tracking detectors, through and around the object, and through two opposite tracking detectors, detecting energy of the protons with a calorimeter, and imaging the object.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: September 22, 2015
    Assignees: Board of Trustees of Northern Illinois University, Fermi Research Alliance, LLC, University of Wollongong
    Inventors: Nicholas Karonis, George Coutrakon, Kirk Duffin, Bela Erdelyi, Kevin Naglich, Scott Penfold, Paul Rubinov, Victor Rykalin, Vishnu Zutshi
  • Patent number: 8742357
    Abstract: A semiconductor radiation sensor (100), comprising a substrate (102), a carrier material (104) mounted to the substrate (102), and a semiconductor detector (106) mounted to the carrier material (104). A radiation sensitive portion of the semiconductor detector (106) is oriented towards the carrier material (104) and generally away from the substrate (102), and the carrier material is adapted to transmit radiation to the radiation sensitive portion of the semiconductor detector (106). A dosimeter comprising the radiation sensor (100) and a method of manufacturing the radiation sensor (100) are also provided.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: June 3, 2014
    Assignee: University of Wollongong
    Inventor: Anatoly Rozenfeld
  • Patent number: 8715610
    Abstract: The present invention relates to a process for the preparation of graphene which can be used in the development of graphene paper or films, graphene-based composites and articles for nanoelectronics, nanocomposites, batteries, supercapacitors, hydrogen storage and bioapplications. This process comprises reducing purified exfoliated graphite oxide in the presence of a base.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: May 6, 2014
    Assignee: University of Wollongong
    Inventors: Gordon George Wallace, Dan Li
  • Patent number: 8524657
    Abstract: The present invention provides a compound of formula I, II, III and IV as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: September 3, 2013
    Assignee: University of Wollongong
    Inventors: Timothy Patrick Boyle, John Barnard Bremmer, Zinka Brkic, Jonathan Alan Victor Coates, Neal Kevin Dalton, John Joseph Deadman, Paul Anthony Keller, Jody Morgan, Stephen Geoffrey Pyne, David Ian Rhodes, Mark James Robertson
  • Patent number: 8421022
    Abstract: A microdosimeter, comprising an array of three-dimensional p-n junction semiconductor detectors, each providing a sensitive volume-target and a tissue equivalent medium for generating secondary charged particles. The array is manufactured from a semiconductor on insulator wafer and the detectors are located to detect secondary charged particles generated in the tissue equivalent medium.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: April 16, 2013
    Assignee: University of Wollongong
    Inventor: Anatoly Rozenfeld
  • Patent number: 8372834
    Abstract: The present invention relates to compositions comprising 5-fluorouracil, or a pharmaceutically acceptable salt or analogue thereof, folinic acid, or a pharmaceutically acceptable salt thereof and a cyclodextrin, or a pharmaceutically acceptable salt or derivative thereof. The invention also relates to methods for the treatment of cancer using such compositions.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: February 12, 2013
    Assignee: University of Wollongong
    Inventors: John Barnard Bremner, Philip Clingan, Julie Myree Locke
  • Patent number: 8242439
    Abstract: A mass spectrometric method for determining the position of unsaturation in a compound is disclosed.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: August 14, 2012
    Assignee: The University of Wollongong
    Inventors: Stephen James Blanksby, David Grant Harman, Michael Christopher Thomas, Todd William Mitchell
  • Patent number: 8212220
    Abstract: A radiation detection apparatus and method, the apparatus (100) comprising a first scintillator (112) for interacting with radiation and outputting light in response thereto, a first photodetector (102) adjacent to the first scintillator (112) for receiving and detecting light from the first scintillator (112) and outputting (108) a first output signal in response thereto, a second scintillator (114) located around the first scintillator (112), for interacting with radiation and outputting light in response thereto, and a second photodetector (104) adjacent to the second scintillator (114) for receiving and detecting light from the second scintillator (114) and outputting (110) a second output signal in response thereto.
    Type: Grant
    Filed: February 8, 2008
    Date of Patent: July 3, 2012
    Assignee: University of Wollongong
    Inventors: Michael Lloyd Franz Lerch, Anatoly Rozenfeld, Olexander Gektin
  • Patent number: 8172998
    Abstract: Ionic liquids are incorporated into transducers, actuators or sensors which employ the ionic polymer membranes. The ionic liquids have superior electrochemical stability, low viscosity and low vapor pressure. The transducers, actuators and sensors which utilize ionic polymer membranes solvated with ionic liquids have long term air stability. Superior results are achieved when a conductive powder and ionomer mixture is applied to the ionic polymer membrane to form the electrodes during or after the ionic liquid is imbibed into the ionic polymer membrane.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: May 8, 2012
    Assignees: Virginia Tech Intellectual Properties, Inc., University of Wollongong
    Inventors: Matthew Bennett, Donald Leo, Gordon Wallace, Geoff Spinks
  • Publication number: 20120108499
    Abstract: The invention relates to new peptoid compounds of formula (I), as well as their use in the treatment of bacterial infections, such as those caused by vancomycin resistant microorganisms, and to compositions thereof.
    Type: Application
    Filed: September 6, 2011
    Publication date: May 3, 2012
    Applicant: University of Wollongong
    Inventors: John BREMNER, Stephen PYNE, Paul KELLER, Dan COGHLAN, Adel GARAS, Helen WITCHARD, Tim BOYLE, Jonathan COATES
  • Patent number: 8039430
    Abstract: The present invention provides a compound of formula (I), (II), (III) and (IV) as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: October 18, 2011
    Assignee: University of Wollongong
    Inventors: Timothy Patrick Boyle, John Barnard Bremner, Zinka Brkic, Jonathan Alan Victor Coates, Neal Kevin Dalton, John Joseph Deadman, Paul Anthony Keller, Jody Morgan, Stephen Geoffrey Pyne, David Ian Rhodes, Mark James Robertson
  • Patent number: 7998934
    Abstract: A method is described for detecting, visualizing, or treating cells, particularly cancerous cells, that express a uPA/uPAR complex. The method employs a PAI-2 conjugate molecule that comprises PAI-2 or a functional derivative, homologue, analogue, chemical equivalent or mimetic thereof, which PAI-2 is bound, linked, or otherwise associated with a toxin or label.
    Type: Grant
    Filed: October 14, 2008
    Date of Patent: August 16, 2011
    Assignees: PAI-2 Pty Limited, University of Wollongong, Medical Scitec Australia Pty Ltd.
    Inventors: Marie Ranson, Barry John Allen, Clive Leighton Bunn
  • Publication number: 20110111962
    Abstract: Improved magnesium diboride superconducting materials and methods of synthesis are disclosed. Embodiments of the superconducting material comprise at least two starting materials capable of forming MgB2 and at least one dopant compound comprising silicon, carbon, hydrogen and oxygen. The starting materials and the at least one dopant compound are heated and mixed at an atomic level to produce a silicon-doped MgB2 superconducting material. Examples of the dopant compound include silicone oil, Triacetoxy(methyl)silane (2), 1,7-Dichloro-octamethyltetrasiloxane (2) and Tetramethyl orthosilicate (6).
    Type: Application
    Filed: July 23, 2007
    Publication date: May 12, 2011
    Applicant: University of Wollongong
    Inventors: Xiaolin Wang, Shi Xue Dou, Md. Shahriar Al Hossain, Zhenxiang Cheng
  • Patent number: 7853412
    Abstract: A method of estimating contact forces between the wheels of a railway wagon and a rail track, for use in determining information such as the likelihood of derailment. Accelerations of the body of the wagon are measured using motion sensors located at suitable points on the body. Forces on the side frames of the wagon are calculated based on the accelerations of the body and predetermined parameters of the body. Forces on the wheels of the wagon are calculated based on the accelerations of the body and predetermined parameters of the body. The contact forces between the wheels and the rails are then calculated based on the forces calculated for the side frames and the wheels. The calculations are carried out using an inverse model of the wagon system. Equipment which implements the method is also described.
    Type: Grant
    Filed: June 8, 2006
    Date of Patent: December 14, 2010
    Assignees: QR Limited, Australian Rail Track Corporation Ltd, Pacific National (Victoria) Ltd, Asciano Services Pty Ltd, TMG Rail Technology Pty Ltd, Rail Corporation NSW, Central Queensland University, University of Wollongong, Monash University, University of South Australia, Queensland University of Technology, The University of Queensland
    Inventors: Fujie Xia, Peter Joseph Wolfs