Abstract: A microdosimeter, comprising an array of three-dimensional p-n junction semiconductor detectors, each providing a sensitive volume-target and a tissue equivalent medium for generating secondary charged particles. The array is manufactured from a semiconductor on insulator wafer and the detectors are located to detect secondary charged particles generated in the tissue equivalent medium.

Abstract: The present invention relates to nanostructured composites, in particular nanotube/substrate composites for use in the fields of biomedical materials and devices as well as energy conversion and storage, ion transport and liquid and gas separation. The use of such composites as biomaterials are of particular interest.

Abstract: The present invention relates to compositions comprising 5-fluorouracil, or a pharmaceutically acceptable salt or analogue thereof, folinic acid, or a pharmaceutically acceptable salt thereof and a cyclodextrin, or a pharmaceutically acceptable salt or derivative thereof. The invention also relates to methods for the treatment of cancer using such compositions.

Abstract: The present invention relates to biocompatible composites, in particular biocompatible nanotube composites in the form of a fiber mat and/or film structure, comprising nanotubes and at least one biomolecule. The invention also relates to a process for preparing a biocompatible composite involving (i) forming a dispersing media comprising nanotubes and at least one biomolecule; and either (ii) introducing the dispersing media of step (i) into a coagulating media optionally comprising at least one biomolecule so as to form a continuous fiber; or (iii) filtering the dispersing media of step (i). Alternatively, the process involves (i) forming a dispersing media comprising nanotubes; and (ii) introducing the dispersing media of step (i) into a coagulating media comprising at least one biomolecule so as to form a continuous fiber. The biocompatible composite is useful as a medical device, preferably in a bio-electrode, bio-fuel cell or substrates for electronically stimulated bio-growth.

Abstract: A content based image retrieval system that extracts images from a database of images by constructing a query set of features and displaying images that have a minimum dissimilarity metric from images in the database. The dissimilarity metric is a weighted summation of distances between features in the query set and features of the images in the database. The method is useful for image searching such as web-based image retrieval and facial recognition.

Abstract: A method of separation and/or recovery of a precious metal from a solution containing said precious metal in ionic form, optionally in the presence of impurities, including the step of contacting a solution containing said precious metal in ionic form with a conducting polymer. The method is generally applicable to precious metals including platinum (Pt), palladium (Pd) and more particularly gold (Au). The ionic species may be anionic (for example [AuCl4]?) or cationic. The polymer may be for example, a polypyrrole or polythiophene, optionally doped and are preferably in a high surface area form eg. coated onto cloth or RVC or in self supporting colloidal form. The polymer may also contain species to give further functionality, eg magnetic or heat sensitive species.

Abstract: The invention relates to new peptoid compounds of formula (I), as well as their use in the treatment of bacterial infections, such as those caused by vancomycin resistant microorganisms, and to compositions thereof.

Abstract: A method of transferring a digital item session state between at least two devices (A, B) using digital items, the method including: providing a content digital item to one of said devices (B); the one of said devices (B) configuring said content digital item according to predetermined requirements; transferring one or more context digital items representing the content digital item's session state from the other device (A) to the one device (B) and the one device (B) configuring said content digital item on the basis of the context digital item. A method of configuring a digital content item on the basis of a stored digital context item is also disclosed.

Abstract: A hybrid homogeneous-heterogeneous catalyst containing catalytic groups, wherein the catalytic activity of the catalyst is largely provided as a result of the interaction of catalytic groups in a suitable proximity and disposition to other catalytic groups, the proximity and disposition resulting from statistical considerations, wherein an example of such catalyst is a polypyrrole-ferrocene monosulfate represented by Formula IV.

Abstract: A method is described for detecting, visualizing, or treating cells, particularly cancerous cells, that express a uPA/uPAR complex. The method employs a PAI-2 conjugate molecule that comprises PAI-2 or a functional derivative, homologue, analogue, chemical equivalent or mimetic thereof, which PAI-2 is bound, linked, or otherwise associated with a toxin or label.

Abstract: A method of estimating contact forces between the wheels of a railway wagon and a rail track, for use in determining information such as the likelihood of derailment. Accelerations of the body of the wagon are measured using motion sensors located at suitable points on the body. Forces on the side frames of the wagon are calculated based on the accelerations of the body and predetermined parameters of the body. Forces on the wheels of the wagon are calculated based on the accelerations of the body and predetermined parameters of the body. The contact forces between the wheels and the rails are then calculated based on the forces calculated for the side frames and the wheels. The calculations are carried out using an inverse model of the wagon system. Equipment which implements the method is also described.

Abstract: The present invention provides a compound of formula (I), (II), (III) and (IV) as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention.

Abstract: A mass spectrometric method for determining the position of unsaturation in a compound is disclosed.

Abstract: A method of separation and/or recovery of a precious metal from a solution containing said precious metal in ionic form, optionally in the presence of impurities, including the step of contacting a solution containing said precious metal in ionic form with a conducting polymer. The method is generally applicable to precious metals including platinum (Pt), palladium (Pd) and more particularly gold (Au). The ionic species may be anionic (for example [AuCl.sub.4].sup.-) or cationic. The polymer may be for example, a polypyrrole or polythiophene, optionally doped and are preferably in a high surface area form eg. coated onto cloth or RVC or in self supporting colloidal form. The polymer may also contain species to give further functionality, eg magnetic or heat sensitive species.

Abstract: The present invention provides a method of determining the dose rate of a radiation source including locating three or more detectors in the vicinity of said source, each for providing an output indicative of the amount of radiation received from said source and determining the location of said source from at least some of said detector outputs, wherein as many of said detector outputs is required to provide an acceptably accurate result are used in determining said location whereby the dose of radiation from said source can be determined from said determined location of said source and either a known activity of said source or a measure of the activity of said source determined by said detectors.

Abstract: An electromechanical actuator comprising an inherently conducting polymer and a conductor for conducing voltage along the polymer from a first end region thereof. The conductor is adapted for axially extending and contracting with axial expansion and contraction of the polymer. In one form, the conductor is in the form of a helix embedded in the polymer and extends along substantially the entire length of the polymer. Also disclosed is a method for manufacture of the electromechanical actuator.

Abstract: The invention relates to new peptoid compounds of formula (I), as well as their use in the treatment of bacterial infections, such as those caused by vancomycin resistant microorganisms, and to compositions thereof.

Abstract: An electroconductive textile comprising: a non-conductive textile such as a wool-containing fabric, a macromolecular template which is bonded to or entrapped in the non-conductive textile such as poly 2-methoxyaniline-5-sulfonic acid (PMAS), and a conductive polymer which is ordered by and bonded to the macromolecular template such as polyaniline; in which the macromolecular template binds the conductive polymer to the non-conductive textile.

Abstract: The invention relates to new peptoid compounds of formula (I), as well as their use in the treatment of bacterial infections, such as those caused by vancomycin resistant microorganisms, and to compositions thereof.

Abstract: A method and apparatus for enabling a Digital Item to be consumed or otherwise manipulated according to a set of operations defined by the Digital Item author or other entitled party, the method including the step of incorporating a Digital Item manipulation method or methods defining said set of operations into the Digital Item.