Abstract: A method utilizing cold welding to prepare grain boundaries having different included angles includes using a device including a support member. Two bent members are arranged opposite to each other in the support member. One ends of the two bent members are both fixedly connected to the support member, one end, away from the support member, of any bent member is fixedly connected to a first sample, one end, away from the support member, of the other bent member is fixedly connected to a second sample, and the first sample and the second sample are arranged corresponding to each other. The bent member includes a first metal sheet and a second metal sheet having different thermal expansion coefficients. An angle between the first sample and the second sample during butt welding can be controlled by changing an included angle of a bimetallic sheet.

Abstract: Processes and device configurations are provided for generating and using flexible storage codes. Methods and configurations described herein can reconstruct and recover data from a distributed network in the event of one or more failures or erasures. According to embodiments, a method includes determining the number of nodes and number of symbols of a flexible storage code, and reconstructing the information using the flexible storage code and determined numbers of nodes and symbols. The flexible storage code may be configured for a flexible number of nodes and symbols for information to use a subarray of symbols and nodes of a storage code array for information. Flexible storage codes may provide a framework for a reconstruction configuration using one or more of a flexible locally recoverable code (LRC), flexible partial maximum distance separable code (PMDSC), and flexible minimum storage regenerating code (MSRC).

Abstract: Non-planar holographic beam shaping lenses for acoustics are disclosed herein. In one embodiment, an ultrasonic therapy system that is configured to apply ultrasound to a target in a body includes: an ultrasonic transducer configured to generate the ultrasound; and a customizable holographic lens configured to focus the ultrasound onto a focal area of a target that is an object or a portion of the object in the body. The customizable holographic lens is designed and produced based on the target. Furthermore, the customizable holographic lens is curved to mate with a front surface of the ultrasonic transducer.

Abstract: Embodiments of the present disclosure provide a software defined network publish-subscribe system and method. The software defined network publish-subscribe system comprises a controller, an administrator controller, a sequencing subsystem and a message multi-backup cache subsystem. The controller is configured to process publish-subscribe transactions in clusters, and comprises sequencing nodes used for generating ordered serial numbers for messages and cache nodes for caching the messages. The administrator controller is configured to simultaneously perform functions of the controller and manage software-defined network. The sequencing subsystem is configured to realize the cooperative sequencing between the administrator controller and the sequencing nodes. The message multi-backup cache subsystem is configured to realize the consistency of the messages through the administrator controller and the cache nodes.

Abstract: The invention pertains to a method for treating a neoplasm, such as colorectal cancer, using hollow silica spheres (“HSS”).

Abstract: The present disclosure relates to a difficult airway evaluation method and device based on a machine learning voice technology. The method includes the following steps: acquiring voice data of a patient; carrying out feature extraction on the voice data, obtaining a pitch period of pronunciations, and acquiring a voiced sound feature and unvoiced sound features based on the pitch period of pronunciations; and constructing a difficult airway evaluation classifier based on the machine learning voice technology, analyzing the received voiced sound feature and unvoiced sound features by the trained difficult airway evaluation classifier, and carrying out scoring on the severity of a difficult airway to obtain an evaluation result of the difficult airway.

Abstract: A polymer composition that operates as a polymer compatibilizer is provided. The polymer composition includes a plurality of polymer backbones cross-linked by cross-links that are Diels-Alder reaction products of at least one dienophile-containing moiety and at least one diene-containing moiety.

Abstract: A compound of Formula I, is disclosed. In Formula I, M is Pd or Pt; each of X1 to X12 is C or N; each of X13 and X14 is CH, CD or N; each of Z1, Z2, and Z3 is C or N; L1 is selected from a variety of bivalent linkers; X is selected from O, S, Se, NR?, and CR?R??; each R, R?, R1, R2, R3, RA, RB, RC, RD, and RE is hydrogen or a General Substituent; at least one of Z1, Z2, and Z3 is a carbon atom substituted with a substituent with a molecular weight of at least 16. Formulations, OLEDs, and consumer products that include Formula I are also disclosed.

Abstract: An attack information processing apparatus (10) includes an extraction unit (11) configured to extract first and second attack knowledge pieces indicating conditions of a cyber attack from first and second attack information pieces including descriptions of the cyber attack, a determination unit (12) configured to determine similarity between the first and second attack information pieces, and a complementing unit (13) configured to complement the first attack knowledge piece with the second attack knowledge piece based on the determined similarity.

Abstract: A three-dimensional photonic crystal template on a reflective substrate displays a periodic patterned from multibeam interference lithography with constructive volumes of a cured photoresist composition and destructive volumes that are voids free of mass containing defects and where the reflective substrate is conductive. A method to generate the three-dimensional photonic crystal template includes using at least four laser beams of unequal intensity, oriented such that a dose of light controlled by the irradiation time generates the periodic pattern with a small dose, where the light reflected from the substrate is insufficient to activate a threshold quantity of photoinitiator in the destructive volumes for the formation of any anomalous condensed matter in the intended void volume.

Abstract: The invention describes a method of generating antibodies to a mixture of peptidogenic proteins wherein the peptidogenic protein has altered conformational dynamics as compared to a starting protein and wherein the peptidogenic protein has a similar conformation to the starting protein. The peptidogenic proteins can be used to induce an immune response, which can lead to the generation of antibodies and/or can be used to vaccinate a mammal.

Abstract: A learning-based active surface model for medical image segmentation uses a method including: (a) data generation: obtaining medical images and associated ground truths, and splitting the sample images into a training set and a testing set; (b) raw segmentation: constructing a surface initialization network, parameters of the network trained by images and labels in the training set; (c) surface initialization: segmenting the images by the surface initialization network, and generating the point cloud data as the initial surface from the segmentation; (d) fine segmentation: constructing the surface evolution network, the parameters of the network trained by the initial surface obtained in step (c); (e) surface evolution: deforming the initial surface points along the offsets to obtain the predicted surface, the offsets presenting the prediction of the surface evolution network; (f) surface reconstruction: reconstructing the 3D volumes from the set of predicted surface points set to obtain the final segmentatio

Abstract: Disclosed herein are embodiments of a nanoparticle composition suitable for delivering a therapeutic agent to a subject by nebulization. The nanoparticle comprises an ionizable lipid, cholesterol or a derivative thereof, a structural lipid, and a PEG lipid. The nanoparticle may partially or completely encapsulate a therapeutic agent, and may be nebulized for administration, such as by inhalation. In some embodiments, the therapeutic agent is mRNA.

Abstract: Disclosed herein are compositions and methods for the treatment and/or detection of diseases such as, but not limited to Lyme disease, Lyme disease-related disorders including post-treatment Lyme disease syndrome (PTLDS), chronic Lyme disease (CLD) and/or inflammation.

Abstract: A method to control the density of a three-dimensional photonic crystal template involves changing the irradiation time from at least four laser beams to yield a periodic percolating matrix of mass and voids free of condensed matter from a photoresist composition. The photoresist composition includes a photoinitiator at a concentration where the dose or irradiation is controlled by the irradiation time and is less than the irradiation time that would convert all photoinitiator to initiating species such that the density of the three-dimensional photonic crystal template differs for different irradiation times. A deposition of reflecting or absorbing particles can be patterned on the surface of the photoresist composition to form a template with varying densities above different areas of the substrate.

Abstract: The preparation method of a starch-based double-loaded functional nanoparticle includes: performing restrictive hydrolysis treatment on egg high-density lipoprotein using proteases to obtain the polypeptide; performing self-assembling on a mixed system containing the polypeptide and quercetin under the alkaline condition to form a micelle nanoparticle; performing covalent grafting reaction on a mixed system containing the micelle nanoparticle and anthocyanin under the alkaline condition to form a graft; and electrostatically compounding carboxymethyl dextrin with the graft to obtain the starch-based double-loaded functional nanoparticle. In the preparation method, raw materials derived from natural sources are used, and the self-assembled colloid nanoparticle with good properties can be obtained by adjusting the pH without any organic reagents.

Abstract: Disclosed are a surface-modified quantum dot surface-modified with a ligand complex having a specific structure on the surface of the semiconductor nanocrystal, a method for preparing the same, and a quantum dot-polymer composite or electronic device including the same.

Abstract: The current disclosure provides novel compositions for treating bacterial infections. Accordingly, aspects of the disclosure relate to an engineered antibody comprising: LCDR1, LCDR2, and LCDR3 of the light chain variable region of the 3F6 antibody and HCDR1, HCDR2, and HCDR3 of the heavy chain variable region of the 3F6 antibody. Also provided are compositions comprising the antibodies and nucleic acids encoding either the heavy chain or light chain (or both) of the antibodies. Other aspects relate to host cells comprising the antibodies and/or nucleic acids of the disclosure. Further aspects relate to a method of preventing or treating staphylococcal infection comprising the step of administering the antibody of the disclosure to a subject in need thereof. Yet further aspects relate to a method of making the antibody comprising expressing the nucleic acid(s) of the disclosure in a cell and isolating the expressed protein.

Abstract: An image encoding/decoding method using a pixel value range constituting an image is disclosed, wherein the image decoding method using a pixel value range constituting an image comprises the steps of: receiving a bitstream; acquiring information of a pixel value range forming a first unit image included in the received bitstream; and decoding the first unit image on the basis of the acquired information of the pixel value range. Therefore, compression efficiency can be improved in an image encoding or decoding process.

Abstract: There is provided a computer implemented method of compressing a baseline dataset comprising a sequence of a plurality of instances of a plurality of unique data elements, the method comprising: providing a weight function that calculates an increasing value for a weight for each one of the plurality of instances of each one of the plurality of unique data elements in the baseline dataset, as a function of increasing number of previously processed sequential locations of each of the plurality of instances of each respective unique data element within the baseline dataset relative to a current sequential location of the baseline dataset, computing an encoding for the baseline dataset according to a distribution of the weight function computed for the plurality of unique data elements in the baseline dataset, and creating a compressed dataset according to the encoding.