Abstract: Various embodiments provide for deep learning-based architectures and design methodologies for an orthogonal frequency division multiplexing (OFDM) receiver under the constraint of one-bit complex quantization. Single bit quantization greatly reduces complexity and power consumption in the receivers, but makes accurate channel estimation and data detection difficult. This is particularly true for OFDM waveforms, which have high peak-to average (signal power) ratio in the time domain and fragile subcarrier orthogonality in the frequency domain. The severe distortion for one-bit quantization typically results in an error floor even at moderately low signal-to-noise-ratio (SNR) such as 5 dB. For channel estimation (using pilots), various embodiments use novel generative supervised deep neural networks (DNNs) that can be trained with a reasonable number of pilots. After channel estimation, a neural network-based receiver specifically, an autoencoder jointly learns a precoder and decoder for data symbol detection.
Type:
Grant
Filed:
October 29, 2019
Date of Patent:
February 7, 2023
Assignee:
Board of Regents, The University of Texas System
Abstract: An electronic or optoelectronic device includes: (1) a layer of a first material; and (2) a layer of a second material disposed on the layer of the first material, wherein the first material is different from the second material, and the layer of the first material is spaced from the layer of the second material by a gap.
Type:
Grant
Filed:
March 19, 2019
Date of Patent:
February 7, 2023
Assignee:
The Regents of the University of California
Abstract: Embodiments include controlling a processor to perform operations, the operations comprising accessing a digitized image of a region of tissue (ROT) demonstrating cancerous pathology; extracting a set of radiomic features from the digitized image, where the set of radiomic features are positively correlated with programmed death-ligand 1 (PD-L1) expression; providing the set of radiomic features to a machine learning classifier; receiving, from the machine learning classifier, a probability that the region of tissue will experience cancer recurrence, where the machine learning classifier computes the probability based, at least in part, on the set of radiomic features; generating a classification of the region of tissue as likely to experience recurrence or non-recurrence based, at least in part, on the probability; and displaying the classification and at least one of the probability, the set of radiomic features, or the digitized image.
Type:
Grant
Filed:
February 18, 2019
Date of Patent:
February 7, 2023
Assignees:
Case Western Reserve University, The Cleveland Clinic Foundation
Abstract: This invention provides substituted bicyclic pyrimidine compounds of the following formula: or a pharmaceutically acceptable salt thereof, wherein R is selected from the group consisting of a straight or a branched chain alkyl group having from 1 to 10 carbon atoms, wherein the alkyl group is partially or completely saturated. Methods of treating a patient diagnosed with cancer are disclosed comprising administering to the patient a therapeutically effective amount of the substituted bicyclic pyrimidine compounds, or a pharmaceutically acceptable salt thereof.
Abstract: A state of a system having a plurality of appliances is controlled by using a device discovery process to establish a listing of each of the plurality of appliances in the system. The listing of each of the plurality of appliances is then used, with reference to a command and/or protocol database, to configure a software agent to exchange communications, via a one or more communication channels, with each of the plurality of appliances. An action triggering state of at least one of the plurality of appliances is associated with an action. The action is performed when it is determined that a current state of the at least one of the plurality of appliances corresponds to the action triggering state.
Abstract: A renal function assessment method includes following steps. A target kidney ultrasound image data of a subject is provided. An image pre-processing step is performed, wherein an image size of the target kidney ultrasound image data is adjusted, and the target kidney ultrasound image data is normalized according to an average and a standard deviation of a visual image database to obtain an after-processed target kidney ultrasound image data. A feature extracting step is performed, wherein the after-processed target kidney ultrasound image data is trained to achieve a convergence by a first deep-learning classifier to obtain an image feature of the after-processed target kidney ultrasound image data. A determining step is performed, wherein the image feature of the after-processed target kidney ultrasound image data is analyzed by the first deep-learning classifier to obtain an assessing result of an estimated glomerular filtration rate (eGFR).
Abstract: A magnetic-field-guidance system and methods of finishing a workpiece using a magnetic-field-guidance system are provided. The magnetic-field-guidance system comprises a workpiece holder, one or more tooling magnets each comprising a finishing tip, and one or more flexible bags containing magnetic media. The workpiece holder is configured to (a) be secured to a base and (b) secure a workpiece relative to the base. The flexible bag(s) are configured to be disposed on the opposite side and/or same side of the workpiece relative to the one or more tooling magnets. In collaboration with the tooling magnets, the magnetic media contained with the flexible bag(s) direct a magnetic field which thereby guides a magnetic-abrasive slurry to finish the workpiece using Magnetic Abrasive Finishing (MAF).
Type:
Grant
Filed:
June 5, 2019
Date of Patent:
February 7, 2023
Assignee:
University of Florida Research Foundation, Incorporated
Abstract: Provided is a method of activating immune cells and/or an immune system response in a subject. The method may comprise administering to a subject an effective amount of a compound of Formula (I): or a prodrug, derivative, and/or salt thereof. In some embodiments, the method comprises contacting an immune cell with a compound of Formula (I) or a prodrug, derivative, and/or salt thereof. Also provided are compounds, compositions, and kits for activating immune cells and/or an immune system response in a subject.
Type:
Grant
Filed:
August 30, 2018
Date of Patent:
February 7, 2023
Assignee:
East Carolina University
Inventors:
Rukiyah T. Van Dross-Anderson, Rene Escobedo
Abstract: Face mask communication system 100 includes face mask 10 worn by user 14 and signal receiving hand glove 16 worn by user 18. Glove 16 includes data receiver 66 for data communication with mask 10 and includes multiple vibrotactile devices for generating haptic signals. Mask 10 includes an elastic element of flexible material, and a plurality of EMG sensors 12 fixed to the element, for sensing electrical activity of face regions of the user's 14 face. Mask 10 includes a processor 60; decoding algorithm 110 and transmitter 62 for, respectively, processing signals from the sensors 12; generating command instructions based on the signals; and wirelessly transmitting the signals to receiver 66 of glove 16. Mask 10 includes thread elements connected to the elastic element of mask 10 enabling tensioning of the element to provide for fitment of mask 10 to users of different sizes, for optimal location sensors 12.
Abstract: The present disclosure describes methods for determining the functional consequences of mutations. The methods include the use of machine learning to identify and quantify features of all atom molecular dynamics simulations to obtain the disruptive severity of genetic variants on molecular function.
Abstract: The present invention provides a self-filtering millimeter-wave wideband multilayer planar antenna. The antenna includes a first layer having a slot feed. A second layer includes at least a pair of probes fed by the slot feed from the first layer. A third layer includes at least two substantially planar radiating patches each patch respectively coupled to one of the probes on the second layer. The radiating patches are arranged to radiate a millimeter-wavelength electromagnetic wave when the slot feed receives excitation energy and transmits the energy to the radiating patch through the respective probe. The self-filtering antenna does not require a resonant cavity structure coupled to the radiating patches. Antenna arrays of arbitrary numbers of antenna elements may be constructed from the self-filtering antenna. Such arrays are particularly suitable for 5G mm-wave backhaul communications.
Abstract: A motor and a spoke-type rotor structure thereof are disclosed. The rotor structure comprises a rotor core which has a plurality of spoke-type first magnetic members. Two oblique second magnetic members arranged in a V shape are provided between every adjacent two of the first magnetic members. A radius of the rotor core is R. A length of the first magnetic member is ls. A length of the second magnetic member is lv. A length component of the second magnetic member on the radius of the rotor core is x. An included angle between the first magnetic member and the second magnetic member is ?. An included angle between every adjacent two of the first magnetic members is ?. The parameters satisfy: ls+x<R, wherein x=lv·cos(180°??); 90°+?/2<?<180°.
Type:
Grant
Filed:
November 30, 2020
Date of Patent:
February 7, 2023
Assignee:
National Cheng Kung University
Inventors:
Mi-Ching Tsai, Min-Fu Hsieh, Kai-Jung Shih, Lucio Jose Fernando Caceres Vera
Abstract: New carbon nanomaterials, preferably titanium carbide-derived carbon (CDC) nanoparticles, were embedded into a polyamide film to give CDC/polyamide mixed matrix membranes by the interfacial polymerization reaction of an aliphatic diamine, e.g., piperazine, and an activated aromatic dicarboxylate, e.g., isophthaloyl chloride, supported on a sulfone-containing polymer, e.g., polysulfone (PSF), layer, which is preferably previously prepared by dry/wet phase inversion. The inventive membranes can separate CO2 (or other gases) from mixtures of CO2 and further gases, esp. CH4, based upon the generally selective nanocomposite layer(s) of CDC/polyamide.
Type:
Grant
Filed:
January 2, 2019
Date of Patent:
February 7, 2023
Assignee:
King Fahd University of Petroleum and Minerals
Abstract: Tropistic materials incorporating a class of adaptively configurable materials capable of real-time detection, tracking, and processing incident stimulus are provided. Incident stimulus can comprise any energetic emission or signals, such as electromagnetic waves, acoustics waves, or magnetic fields. The materials comprise a deformable stimuli-responsive material, which can adapt configuratively to a specific stimulus, and may further comprise a plurality of absorbers or photo-sensitive molecules configured to convert external incident stimuli to the specific stimulus type toward which the deformable material is responsive.
Type:
Grant
Filed:
April 11, 2018
Date of Patent:
February 7, 2023
Assignee:
The Regents of the University of California
Abstract: Disclosed herein, inter alia, are acyclic nucleotide analogs and methods of using an acyclic nucleotide analog for treating and/or ameliorating a papillomavirus infection.
Type:
Grant
Filed:
April 21, 2021
Date of Patent:
February 7, 2023
Assignee:
The Regents of the University of California
Inventors:
Karl Y. Hostetler, James R. Beadle, Nadejda Valiaeva
Abstract: A preparation method of a zirconium-titanium-based alloy embedded aluminized layer includes putting a zirconium-titanium-based alloy and an aluminiferous penetrant into a mould from bottom to top in a sequence of a first penetrant layer, a first zirconium-titanium-based alloy, a second penetrant layer, a second zirconium-titanium-based alloy and a third penetrant layer, and compacting to obtain a mixed sample; sequentially covering a surface of a mixed sample with activated carbon powder and alkali metal halide, and then carrying out heating and cooling treatments to obtain a zirconium-titanium-based alloy embedded aluminized layer. The preparation method does not need to adopt a special heating furnace or carry out heat treatment under a vacuum condition in an actual application, which simplifies operation process and condition and is suitable for large-scale production and application due to few technical difficulties and low equipment investment cost.
Type:
Grant
Filed:
June 11, 2021
Date of Patent:
February 7, 2023
Assignee:
Yanshan University
Inventors:
Xinyu Zhang, Yize Liu, Jiaqian Qin, Riping Liu
Abstract: The disclosure relates to a prefabricated movable photosensitively adjustable solar bionic landscape pavilion capable of being disassembled and constructed quickly. The landscape pavilion comprises a support structure, a ceiling, a movable platform, a linkage system, a lighting system, and an energy system. The support structure is arranged at the center of the movable platform and forms large-area shelter space with the ceiling. The ceiling may rotate around the support structure in the height direction of the support structure, so as to be unfolded or folded. The movable platform is a base of the landscape pavilion, undertakes the support structure and the ceiling above the movable platform, and meanwhile, provides fixing space for the linkage system, the lighting system, and the energy system.
Abstract: Disclosed is a method for determining a mixing temperature of an asphalt mixture which includes the following steps: S100, obtaining a test result of surface energy of hot-melt asphalt; S200, obtaining, according to a calculation formula for total adhesion work and in combination with the test result of the surface energy of the hot-melt asphalt, total adhesion work of an asphalt and aggregate interface at different mixing temperatures; S300, determining a temperature range corresponding to peak values of the total adhesion work of the asphalt and aggregate interface; and S400, calculating a median value of the temperature range determined in S300, so as to determine an optimum mixing temperature of the asphalt mixture.
Type:
Grant
Filed:
June 11, 2021
Date of Patent:
February 7, 2023
Assignee:
Tongji University
Inventors:
Liping Liu, Lijun Sun, Qingbing Lu, Mingchen Li
Abstract: An underwater acoustic communication system for a mobile electronic device, such as a smartphone, has a communication unit with one or more ultrasonic transducers to transmit and receive underwater ultrasonic signals. The communication unit is connected to an audio auxiliary interface of the mobile electronic device. A processing unit in communication with the auxiliary interface receives RF signals from and transmits RF signals to the communication unit via the audio auxiliary interface.
Type:
Grant
Filed:
May 30, 2018
Date of Patent:
February 7, 2023
Assignee:
Northeastern University
Inventors:
Francesco Restuccia, Emrecan Demirors, Tommaso Melodia
Abstract: The disclosure provides products and methods of treating diseases and disorders involving microbial pathogens, such as intestinal microbial pathogens, e.g., Pseudomonas aeruginosa, by administering an effective amount of a phosphorylated polyethylene glycol compound of defined structural organization. Those diseases and disorders characterized by an epithelium attacked by a microbial pathogen are contemplated, including gastrointestinal infections and inflammation, e.g., treatment of intestinal or esophageal anastomosis or treatment or suppression of anastomotic leakage.
Type:
Grant
Filed:
September 29, 2017
Date of Patent:
February 7, 2023
Assignee:
The University of Chicago
Inventors:
John C. Alverdy, Matthew Tirrell, Olga Y. Zaborina, Jun Mao, Wei Chen