Abstract: A new layer tailored for Artificial Intelligence-based communication systems to limit the instantaneous peak power for the signals that relies on manipulation of complementary sequences through neural networks. Disclosed is a method for providing non-linear distortion in end-to-end learning communication systems, the communication system comprising a transmitter and a receiver. The method includes mapping transmitted information bits to an input of a first neural network; controlling, by an output of the neural network, parameters of a complementary sequence (CS) encoder, producing an encoded CS; transmitting the encoded CS through an orthogonal frequency division multiplexing (OFDM) signal; processing, by Discrete Fourier Transform (DFT), the encoded CS, to produce a received information signal in a frequency domain; and processing, by a second neural network, the received information signal.

Abstract: The present invention relates to the unexpected discovery of novel methods of preparing nanodevices and/or microdevices with predetermined patterns. In one aspect, the methods of the invention allow for engineering structures and films with continuous thickness equal to or less than 50 nm.

Abstract: A method for the prediction, prognosis and/or diagnosis of bladder cancer or bladder cancer recurrence in a subject, the method includes: providing a test sample from the subject; measuring DNA methylation levels of at least a portion of two or more polynucleotides selected from the group consisting of HOXA9, SOX1, NPY, IRAK3, L1-MET, and ZO2 in the test sample; calculating a risk score based on the measured DNA methylation levels, comparing the calculated risk score to a cut-off value derived from a reference DNA methylation profile based on DNA methylation levels of the one or more biomarkers derived from a control group, members of which had bladder cancer; and based on the comparison calculated risk score to the cut-off value, determining at least one of: (1) whether bladder cancer has recurred; (2) whether there is likelihood that the bladder cancer will recur; and (3) whether the patient has bladder cancer.

Abstract: An insulating composition having a polymer resin, a nanoclay, and one or more nanofillers. The insulating composition has a thermal conductivity of greater than about 0.8 W/mK, a dielectric constant of less than about 5, a dissipation factor of less than about 3%, and a breakdown strength of greater than about 1,000V/mil. The insulating composition has an endurance life of at least 400 hours at 310 volts per mil.

Abstract: The invention provides for novel MAP kinase inhibitors and compositions comprising the same. In some embodiments, the MAP kinase inhibitors are p38? MAP kinase inhibitors. The invention further provides for methods for treatment of diseases comprising administration of MAP kinase inhibitors or compositions comprising MAP kinase inhibitors. In some embodiments, the disease is Alzheimer's Disease, ALS, Huntington's Disease or Parkinson's Disease.

Abstract: A series of phenelzine analogs comprising a phenelzine scaffold linked to an aromatic moiety and their use as inhibitors of lysine-specific demethylase 1 (LSD1) and/or one or more histone deacetylases (HDACs) is provided. The presently disclosed phenelzine analogs exhibit potency and selectivity for LSD1 versus MAO and LSD2 enzymes and exhibit bulk, as well as, gene specific histone methylation changes, anti-proliferative activity in several cancer cell lines, and neuroprotection in response to oxidative stress. Accordingly, the presently disclosed phenelzine analogs can be used to treat diseases, conditions, or disorders related to LSD1 and/or HDACs, including, but not limited to, cancers and neurodegenerative diseases.

Abstract: The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease.

Abstract: A deformable body for a force/torque sensor which may be attached to robots formed with multiple axes and multiple joints includes a substrate in which a hole is formed, a disc disposed above the hole, and a plurality of hinges protruding from a side surface of the disc and connecting the disc and the substrate.

Abstract: A configurable input element of a controlling device is configured by using a data representative of an over-the-top (OTT) media app determined to be installed on an OTT device and a data representative of the OTT device to identify at least one command that is required to be transmitted to cause the OTT device to launch the OTT media app. The at least one command is provisioned to the controlling device and assigned to the configurable input element. When the input element is subsequently activated, the controlling device will transmit the at least one command to cause the OTT device to launch the OTT media app.

Abstract: In certain embodiments a device is provided for electrorotation flow. In certain embodiments the device comprises a microfluidic channel comprising a plurality of electrodes disposed to provide dielectrophoretic (DEP) forces that are perpendicular to hydrodynamic flows along the channel; and a fluid within the channel providing the hydrodynamic flow along the channel; wherein the device is configured to apply focusing voltages to the electrodes that provide an electric field minimum in the channel and that focus cells, particles, and/or molecules or molecular complexes within the channel; and where the device is configured to apply rotation-inducing voltages to the electrodes that induce rotation of the cells, particles, molecules and/or molecular complexes as they flow through the channel.

Abstract: Biologically-inspired compositions, including color changing compositions, and corresponding embodiments such as sensors, textile materials, coatings and films, are provided which typically include a solid, transparent and nondegradable matrix. The matrix contains a plurality of (i) synthetic particles having a size in the micrometer or nanometer range, each synthetic particle including one or more aggregates of a pigment selected from phenoxazone, phenoxazine, and a derivate or precursor thereof, and a stabilizing material which has a refractive index larger than 1.45, the aggregates having a size larger than about 100 nm; or (ii) submicrometer natural particles extracted and purified from homogenized tissue.

Abstract: The present disclosure relates to 2-(3-indoyl)indolin-3-one derivatives of the natural product isatisine A, synthesized from dual catalytic synthesis on metallocarbene-azide cascade chemistry, useful for treating a subject having or suspected of having an infectious disease, wherein the infection disease is caused by a virus, wherein the virus is from the family flaviviridae or paramyxoviridae.

Abstract: A renal cortex targeting elastin-like polypeptide (ELP), a renal medulla and cortex targeting ELP, and a method of treating a renal disorder are provided. The renal cortex targeting ELP includes up to 95 repeat units having the sequence VPGXG (SEQ ID NO: 1), where X in each of the repeat units is any amino acid except proline. The renal medulla and cortex targeting ELP includes at least 95 repeat units of SEQ ID NO: 1, where X in each of the repeat units is any amino acid except proline. The method of treating a renal disorder includes administering an ELP and a therapeutic drug to a subject in need thereof, where the ELP includes up to 671 repeat units of SEQ ID NO: 1 and X in each of the repeat units is any amino acid except proline.

Abstract: A system for neuromodulation includes a split-ring resonator (SRR) comprising a resonance circuit, the SRR being implantable in a cranial target site and a source of microwave signals, wherein the microwave signals are deliverable wirelessly to couple with the SRR to produce a localized electrical field, wherein the localized electrical field inhibits one or more neurons at the cranial target site with submillimeter spatial precision.

Abstract: A fuel cell control method and system based on model prediction control are provided. The method includes: (1) obtaining data required for control; (2) determining whether the data required for control are received completely; (3) estimating an internal state of a fuel cell based on outlet pressure of an air compressor and a voltage of the fuel cell to obtain a state estimation result; (4) calculating a target outlet flow of the air compressor and a target current of the fuel cell with a model prediction control algorithm based on the state estimation result; (5) calculating a control voltage of the air compressor, and a target outlet flow of the air compressor; and (6) tracking power of the fuel cell based on the target current of the fuel cell, and controlling air supply of the fuel cell based on the control voltage of the air compressor.

Abstract: A device that non-invasively detects objects beneath or around the foot or a foot position and transmits signals which are processed and then output via an output device on a skin surface not affected by a neurological deficit, such as the hands or thighs. This device is suitable for subjects with diabetic neuropathy who have lost sensation in their feet and are at risk of punctures, cuts or other physical damage and at risk of sprains, strains or falls due to lack of an ability to detect objects underfoot and foot position.

Abstract: An OLED is disclosed that includes an enhancement layer having optically active metamaterials, or hyperbolic metamaterials, which transfer radiative energy from the organic emissive material to a non-radiative mode, wherein the enhancement layer is disposed over the organic emissive layer opposite from the first electrode, and is positioned no more than a threshold distance away from the organic emissive layer, wherein the organic emissive material has a total non-radiative decay rate constant and a total radiative decay rate constant due to the presence of the enhancement layer, and the threshold distance is where the total non-radiative decay rate constant is equal to the total radiative decay rate constant; and an outcoupling layer disposed over the enhancement layer, wherein the outcoupling layer scatters radiative energy from the enhancement layer to free space.

Abstract: Systems, methods, and non-transitory computer-readable storage media for a fast power network simulator. A system configured per this disclosure can use identify a power network, the power network comprising generators, transmission lines, and loads, and receive a model of the power network. The model of the power network can include: models of the generators modeled as differential equations, and models of the transmission lines and the loads modeled as algebraic equations. The system can convert, via a processor, the algebraic equations of the models of the transmission lines and the loads to additional differential equations, then combine, via the processor, the differential equations and the additional differential equations, to yield combined differential equations. The system can then iteratively solve linear equations, via the processor, associated with the combined differential equations, to yield solutions, and output the solutions as part of a power simulation of the power network.

Abstract: Systems and methods for monitoring food intake include an air pressure sensor for detecting ear canal deformation, according to some implementations. For example, the air pressure sensor detects a change in air pressure in the ear canal resulting from mandible movement. Other implementations include systems and methods for monitoring food intake that include a temporalis muscle activity sensor for detecting temporalis muscle activity, wherein at least a portion of the temporalis muscle activity sensor is coupled adjacent a temple portion of eyeglasses and disposed between the temple tip and the frame end piece. The temporalis muscle activity sensor may include an accelerometer, for example, for detecting movement of the temple portion due to mandibular movement from chewing.