Patents Assigned to University
  • Patent number: 11492905
    Abstract: A lidar-based convergence deformation monitoring system for surrounding rock around a TBM shield region, including a data acquisition module. The data acquisition module includes: a lidar, a push-rod motor, an H-bridge circuit, a power supply module, an ARM chip, a guide rod, a linear bearing, a tempered glass cover and a protective case. The lidar and the push-rod motor are connected to a lidar connector to acquire raw data of the surrounding rock and store the raw data in the ARM chip. A middle portion of a top plate of the protective case allows the lidar to extend out of the protective case. The protective case is fastened to an inner wall of the TBM shield through two mounting brackets on both sides of the protective case, and the inner wall facilitates the lidar to extend out of the protective case to perform a measurement.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: November 8, 2022
    Assignees: Institute of Rock and Soil Mechanics, Chinese Academy of Sciences, Wuhan University
    Inventors: Xing Huang, Quansheng Liu, Xianze Xu, Tong Zheng, Xiaoping Zhang, Fengqiu Xu
  • Patent number: 11495694
    Abstract: Fabricating a vertical-channel junction field-effect transistor includes forming an unintentionally doped GaN layer on a bulk GaN layer by metalorganic chemical vapor deposition, forming a Cr/SiO2 hard mask on the unintentionally doped GaN layer, patterning a fin by electron beam lithography, defining the Cr and SiO2 hard masks by reactive ion etching, improving a regrowth surface with inductively coupled plasma etching, removing hard mask residuals, regrowing a p-GaN layer, selectively etching the p-GaN layer, forming gate electrodes by electron beam evaporation, and forming source and drain electrodes by electron beam evaporation. The resulting vertical-channel junction field-effect transistor includes a doped GaN layer, an unintentionally doped GaN layer on the doped GaN layer, and a p-GaN regrowth layer on the unintentionally doped GaN layer. Portions of the p-GaN regrowth layer are separated by a vertical channel of the unintentionally doped GaN layer.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: November 8, 2022
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Yuji Zhao, Chen Yang, Houqiang Fu, Xuanqi Huang, Kai Fu
  • Patent number: 11492611
    Abstract: Systems and methods for enhancing RNA translatability and stability are disclosed. Some embodiments describe RNA molecules exhibiting increased translatability and/or stability. Additional embodiments describe methods for screening RNA molecules for increased translatability and/or stability. Various embodiments utilize screening methods, including degenerative sequences to identify sequences or regions that increase the translatability and/or stability of RNA molecules.
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: November 8, 2022
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Maria Barna, Kathrin Leppek, Gun Woo Byeon
  • Patent number: 11491257
    Abstract: Embodiments of the present disclosure provide for structures including an alloy of calcium, strontium, and magnesium.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: November 8, 2022
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Michele Viola Manuel, Ida E. Svensson Berglund, Benjamin G. Keselowsky, Malisa Sarntinoranont, Harpreet Singh Brar, Hunter B. Henderson
  • Patent number: 11491241
    Abstract: This invention relates to polynucleotides comprising optimized aspartylglucosaminidase (AGA) open reading frames and vectors and cells comprising the same. The invention further relates to methods of using the same for delivery of the open reading frame to a cell or a subject and methods for treating aspartylglucosaminuria (AGU) in a subject.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: November 8, 2022
    Assignee: The University of North Carolina at Chapel Hill
    Inventor: Steven James Gray
  • Patent number: 11494643
    Abstract: A noise data artificial intelligence learning method for identifying the source of problematic noise may include a noise data pre-conditioning method for identifying the source of problematic noise including: selecting a unit frame for the problematic noise among noises sampled with time; dividing the unit frame into N segments; analyzing frequency characteristic for each segment of the N segments and extracting a frequency component of each segment by applying Log Mel Filter; and outputting a feature parameter as one representative frame by averaging information on the N segments, wherein an artificial intelligence learning by the feature parameter extracted according to a change in time by the noise data pre-conditioning method applies Bidirectional RNN.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: November 8, 2022
    Assignees: Hyundai Motor Company, Kia Motors Corporation, IUCF-HYU (Industry-University Corporation Foundation Hanyang University)
    Inventors: Dong-Chul Lee, In-Soo Jung, Joon-Hyuk Chang, Kyoung-Jin Noh
  • Patent number: 11492361
    Abstract: The invention relates to compounds of Formula (I), salts thereof, combinations, pharmaceutical compositions thereof, as well as therapeutic methods of treatment and prevention.
    Type: Grant
    Filed: October 5, 2020
    Date of Patent: November 8, 2022
    Assignees: GlaxoSmithKline Intellectual Property Development Limited, The University of North Carolina at Chapel Hill, ViiV Healthcare Company
    Inventors: Richard M. Dunham, David Margolis, Vincent Wing-Fai Tai, Jun Tang
  • Patent number: 11492588
    Abstract: The disclosure discloses Lactococcus lactis subsp. lactis CCFM1018 and application thereof in preparation of food and medicine for excreting a plasticizer, and belongs to the technical field of microorganisms. The Lactococcus lactis subsp. lactis CCFM1018 not only is significantly better than the intestinal resident bacteria Escherichia coli and Enterococcus faecalis in terms of the effect of promoting the excretion of DEHP and MEHP, but also is better than the commercial strain Lactobacillus rhamnosus LGG. Therefore, the Lactococcus lactis subsp. lactis CCFM1018 of the disclosure can be used as an effective means to prevent and alleviate body damage caused by DEHP and MEHP, and does not have toxic or side effects of drugs. Lactococcus lactis subsp. lactis CCFM1018 can be used to prepare pharmaceutical compositions and fermented food for alleviating and preventing the toxicity of DEHP and metabolites thereof, and has a very broad application prospect.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: November 8, 2022
    Assignee: Jiangnan University
    Inventors: Gang Wang, Wei Chen, Qian Chen, Jianxin Zhao, Hao Zhang
  • Patent number: 11491210
    Abstract: Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and/or virulent bacteria in a mixed bacteria population, or for reducing any other type of unwanted bacteria in a mixed bacteria population. The compositions and methods involve targeting bacteria that are differentiated from other members of the population by at least one unique clustered regularly interspaced short palindromic repeats (CRISPR) targeted DNA sequence. The compositions and methods can be readily adapted to target any bacteria or any bacteria plasmid, or both.
    Type: Grant
    Filed: March 29, 2022
    Date of Patent: November 8, 2022
    Assignee: The Rockefeller University
    Inventors: David Bikard, Luciano Marraffini
  • Patent number: 11493751
    Abstract: An optical relay comprises a first scan mirror configured to receive an input optical beam, and to reflect the input optical beam as a first intermediate optical beam; a telecentric mirror configured to receive the first intermediate optical beam, and to reflect the first intermediate optical beam as a second intermediate optical beam; a second scan mirror configured to receive the second intermediate optical beam, and to reflect the second intermediate optical beam as an output optical beam; and a lens system disposed between the telecentric mirror and the first and second scan mirrors, such that the first intermediate optical beam and the second intermediate optical beam pass through the lens system. The optical relay may be a component of an optical system which further includes an optical engine.
    Type: Grant
    Filed: January 23, 2020
    Date of Patent: November 8, 2022
    Assignee: Vanderbilt University
    Inventors: Yuankai Tao, Joseph D. Malone
  • Patent number: 11491244
    Abstract: The present application is in the field of imaging reagents. In particular, the present application relates to labelled fluorocarbon imaging reagents, the preparation of the reagents, and their uses for imaging such as PET scanning.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: November 8, 2022
    Assignees: Sunnybrook Research Institute, McMaster University
    Inventors: John Valliant, Naomi Matsuura
  • Patent number: 11494901
    Abstract: A telepathology system is associated with an edge network shared among participating users for remote control of a microscope. The microscope includes a camera operable to receive image data of a specimen. The telepathology system is capable of receiving image data from the microscope, pre-processing the image data at network edge, sending the pre-processed image digitally to the participating users via a web server on the edge network, and controlling the image data, via instructions from the participating users.
    Type: Grant
    Filed: May 21, 2020
    Date of Patent: November 8, 2022
    Assignee: Saint Louis University
    Inventor: Flavio Esposito
  • Patent number: 11492362
    Abstract: Methods of inducing apoptosis of cancer cells by contacting the cancer cells with a pyridine derivative are provided. Methods of treating a subject suffering from a hyperproliferative disease or complications thereof comprising the step of administering a therapeutically effective amount of a composition to the subject, wherein the composition comprises pyridine derivatives are provided.
    Type: Grant
    Filed: February 17, 2022
    Date of Patent: November 8, 2022
    Assignee: King Abdulaziz University
    Inventors: Khadijah M. Al-Zaydi, Meaad Bagazi, Tamer Said Saleh
  • Patent number: 11495355
    Abstract: A method, system and computer readable medium of: providing feature data of at least one organ at risk or target volume of said patient from a database of non-transitory data stored on a data storage device of prior patients data; generating, using a data processor, a distribution of dose points of the at least one organ at risk or target volume of said patient based on said feature data; calculating, using the data processor, at least one of (i) a probability of toxicity for the at least one organ at risk or (ii) a probability of treatment failure for the at least one target volume, based on said distribution of dose points; assessing, using the data processor, a dosimetric-outcome relationship based on the calculated probability; and automatically formulating, using the data processor, a treatment plan using the dosimetric-outcome relationship to minimize the at least one treatment-related risk.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: November 8, 2022
    Assignee: The Johns Hopkins University
    Inventors: Todd McNutt, Joseph Moore, Scott Robertson, Fumbeya Marungo
  • Patent number: 11490987
    Abstract: An ultrasound-detectable marker, ultrasound system, and methods for monitoring vascular flow and patency is disclosed. The ultrasound-detectable marker comprises one or more resorbable polymers, one or more non-resorbable polymers, one or more non-polymeric materials, or any combinations thereof. The ultrasound-detectable marker is adapted for placement underneath, adjacent to, or above one or more vessels at a postoperative site, such as a vascular anastomosis site. Further, the ultrasound imaging system includes certain user guiding software and/or health analysis software for use with the ultrasound-detectable marker.
    Type: Grant
    Filed: March 3, 2021
    Date of Patent: November 8, 2022
    Assignee: The Johns Hopkins University
    Inventors: Devin O'Brien-Coon, Kaitlyn Harfmann, Ting Yu Lai, David Narrow, Adam Lightman, Youseph Yazdi
  • Patent number: 11491217
    Abstract: The present disclosure relates to Zika vaccines. In certain embodiments, this disclosure relates to vaccine compositions for use in methods of protecting a human subject against Zika disease or infection, wherein said composition comprises a vaccinal for Zika such as a live attenuated or inactivated chimeric Zika virus; live attenuated Zika virus; an inactivated Zika virus; a replication-defective pseudo-infectious Zika virus; a Zika virus-like particle (VLP), a Zika protein or combinations thereof. In certain embodiments, the Zika vaccinal comprises or encodes altered polypeptide sequences disclosed herein.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: November 8, 2022
    Assignees: Emory University, Children's Healthcare of Atlanta, Inc.
    Inventor: Baek Kim
  • Patent number: 11491265
    Abstract: A mechanical vacuum dressing comprising: a first valve layer comprising a first one-way valve; a second valve layer comprising a second one-way valve; the first valve layer being joined to the second valve layer so as to define a chamber therebetween; the first one-way valve being configured to admit fluid into the chamber through the first one-way valve but prevent fluid from exiting the chamber through the first one-way valve; the second one-way valve being configured to exhaust fluid from the chamber through the second one-way valve but prevent fluid from entering the chamber through the second one-way valve; and the second valve layer comprising an elastomeric material such that (i) when the second valve layer is moved away from the first valve layer, the volume of the chamber is increased, and (ii) when the second valve layer is thereafter released, the second valve layer moves back towards the first valve layer and the volume of the chamber is decreased.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: November 8, 2022
    Assignee: Cornell University
    Inventors: Sang Lee, Anthony Assal, Matthew Baird, John Frederick Cornhill, Russell Corwin, Andrew Harvey, Jeffrey Milsom, Anh Nguyen, Jia Xing, James Goldie, Vladimir Gilman, Minh Duong, Jennifer Vondran, Blair Hough, Gerard I. Libby, Timothy Norman Johnson, Darwin T. Keith-Lucas
  • Patent number: 11492494
    Abstract: A method of increasing the strength of a carbonate rock is described. The carbonate rock may be located within a subterranean carbonate formation or may be located on a building exterior. The method involves contacting the carbonate rock with a composition comprising a zinc salt or a silicon alkoxide. This may increase the hardness of the carbonate rock by 10% or more.
    Type: Grant
    Filed: March 24, 2020
    Date of Patent: November 8, 2022
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Mahmoud Desouky, Murtada Al Jawad, Theis Ivan Solling
  • Patent number: 11491327
    Abstract: A bio electrode and a method of forming the same are provided. The bio electrode comprises a first core-shell nanowire/polymer composite comprising a first core-shell nanowire and a first polymer. The method of forming a bio electrode comprises a step of forming a core-shell nanowire by carrying out epitaxial growth of a biocompatible metal on a surface of a core comprising a conductive metal.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: November 8, 2022
    Assignees: Seoul National University R&DB Foundation, INSTITUTE FOR BASIC SCIENCE
    Inventors: Daehyeong Kim, Taeghwan Hyeon, Suji Choi, Sangihn Han, Dongjun Jung
  • Patent number: 11491729
    Abstract: A method for training a machine learning engine for modeling of a physical system includes receiving process data representing measurements of a physical system. The method includes applying a transform to values of the at least two variables of the process data to generate a dimensionless parameter having a parameter value corresponding to each measurement of the physical system for the at least two variables. The method includes training the machine learning engine using a set of generated training data including the non-dimensionalized parameter, to output a prediction of a value of a physical effect of the physical system for values of the variables that are not included in the process data. The method includes controlling an additive manufacturing process for the material by setting the at least one physical property to the value of the at least one process variable during fabrication of a part.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: November 8, 2022
    Assignee: Carnegie Mellon University
    Inventors: Sneha Prabha Narra, Jack Lee Beuth, Jr.