Patents Assigned to University
  • Patent number: 11230606
    Abstract: Humanized antibody to a pathologically mislocated form of N-cadherin detects and eliminates cells that express the protein extracellularly. These cells are found in fibrotic conditions within heart, lung, and liver, as well as kidney, skin, and other organs effected by fibrosis. The antibody does not affect cells with normal, subcellular location of the protein.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: January 25, 2022
    Assignee: Duke University
    Inventors: Paul Ferrell, Salvatore Pizzo, Robin Bachelder
  • Patent number: 11232869
    Abstract: A triage system that determines whether a user is likely to have contracted a disease based on sensor data received from a user device (e.g., a smartphone or activity tracker). Some symptoms are identified by comparing sensor data to a predetermined baseline and comparing the difference to a predetermined symptom threshold. Those comparisons are weighted to form a composite metric, which is compared to a composite threshold to determine if the user is likely to have contracted the disease. Because different individuals are at higher risk of contracting certain diseases, the determined based on specific characteristics of the user (e.g., potential comorbidities, age, gender, ethnic, racial, cultural, or economic status, geographic location, level of interaction with other individuals, etc.) that that have been identified in medical literature as increasing the individual's risk.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: January 25, 2022
    Assignee: Georgetown University
    Inventors: Howard Federoff, Ophir Frieder
  • Patent number: 11232319
    Abstract: A computerized method of providing automatic anatomy recognition (AAR) includes gathering image data from patient image sets, formulating precise definitions of each body region and organ and delineating them following the definitions, building hierarchical fuzzy anatomy models of organs for each body region, recognizing and locating organs in given images by employing the hierarchical models, and delineating the organs following the hierarchy. The method may be applied, for example, to body regions including the thorax, abdomen and neck regions to identify organs.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: January 25, 2022
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Jayaram K. Udupa, Dewey Odhner, Drew A. Torigian, Yubing Tong
  • Patent number: 11230517
    Abstract: Disclosed is a fluorination method comprising providing an aryl fluorosulfonate and a fluorinating reagent to a reaction mixture; and reacting the aryl fluorosulfonate and the fluorinating reagent to provide a fluorinated aryl species. Also disclosed is a fluorination method comprising providing, a salt comprising a cation and an aryloxylate, and SO2F2 to a reaction mixture; reacting the SO2F2 and the ammonium salt to provide a fluorinated aryl species. Further disclosed a fluorination method comprising providing a compound having the structure Ar—OH to a reaction mixture; where Ar is an aryl or heteroaryl; providing SO2F2 to the reaction mixture; providing a fluorinating reagent to the reaction mixture; reacting the SO2F2, the fluorinating reagent and the compound having the structure Ar—OH to provide a fluorinated aryl species having the structure Ar—F.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: January 25, 2022
    Assignees: The Regents of the University of Michigan, Dow Global Technologies LLC
    Inventors: Melanie S. Sanford, Douglas Bland, Patrick S. Hanley, Megan A. Cismesia, Sydonie D. Schimler
  • Patent number: 11229608
    Abstract: Compositions and methods for systemic delivery of at least one cargo in a vascular plant. Compositions may include at least one cargo delivery particle, having a core and a shell; and at least one cargo disposed on the shell. The core may include at least one micronutrient. The shell may include a coating material. The at least one cargo delivery particle may have a size of less than about 10 nanometers. Methods may include administering an effective amount of the compositions to a plant.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: January 25, 2022
    Assignees: University of Central Florida Research Foundation, Inc., ICAR-Central Citrus Research Institute, Indian Institute Technology ROORKEE
    Inventors: Swadeshmukul Santra, Ali Ozcan, Dilip K. Ghosh, Sunil Kokane, Pranav Kumar, Ashwani Kumar Sharma
  • Patent number: 11229683
    Abstract: Methods and compositions comprising hematopoietic growth factor proteins and/or protein analogs thereof and/or combinations thereof and angiotensin converting enzyme inhibitors to treat the acute and long term adverse effects of radiation exposure in subjects who have been or will be exposed to radiation are disclosed.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: January 25, 2022
    Assignees: Bolder Biotechnology, Inc., Indiana University Research and Technology Corporation, The Medical College of Wisconsin, Inc.
    Inventors: George N. Cox, Christie M. Orschell, Meetha Manek Medhora, Brian Fish
  • Patent number: 11230607
    Abstract: Methods are provided for treating a subject with for an intracellular pathogen infection, by administering an agent that reduces the binding of CD47 on a infected cell to SIRP? on a host phagocytic cell, in an effective dose for increasing the phagocytosis of infected cells.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: January 25, 2022
    Assignees: The Board of Trustees of the Leland Stanford Junior University, The United States of America as represented by the Secretary, Department of Health and Human Services, The Regents of the University of California
    Inventors: Kipp Andrew Weiskopf, Kim J. Hasenkrug, Cheryl A. Stoddart, Joseph McCrary McCune, Irving L. Weissman
  • Patent number: 11231469
    Abstract: A pulsed magnetic particle imaging system includes a magnetic field generating system that includes at least one magnet, the magnetic field generating system providing a spatially structured magnetic field within an observation region of the magnetic particle imaging system such that the spatially structured magnetic field will have a field-free region (FFR) for an object under observation having a magnetic nanoparticle tracer distribution therein. The pulsed magnetic particle imaging system also includes a pulsed excitation system arranged proximate the observation region, the pulsed excitation system includes an electromagnet and a pulse sequence generator electrically connected to the electromagnet to provide an excitation waveform to the electromagnet, wherein the electromagnet when provided with the excitation waveform generates an excitation magnetic field within the observation region to induce an excitation signal therefrom by at least one of shifting a location or condition of the FFR.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: January 25, 2022
    Assignee: The Regents of the University of California
    Inventors: Steven M. Conolly, Patrick W. Goodwill, Daniel Hensley, Zhi Wei Tay, Bo Zheng
  • Patent number: 11229680
    Abstract: Provided herein are recombinant peptides useful for inhibiting the function of autophagy-related 8 (Atg8) proteins. The recombinant peptides can be used in the preparation of imaging agents for monitoring autophagy in a cell or subject and treating autophagy related diseases, such as cancer.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: January 25, 2022
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Mingjie Zhang, Jianchao Li, Ruichi Zhu, Chao Wang
  • Patent number: 11232743
    Abstract: Devices and techniques are provided in which an OLED panel is operated in two modes. The first mode operates in a standard way to display an image or video or otherwise illuminate sub-pixels of the panel. In the second mode, some pixels are operated at a lower brightness than in the first mode. The use of multiple modes allows for improved sub-pixel lifetime and reduced sub-pixel and image degradation.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: January 25, 2022
    Assignee: Universal Display Corporation
    Inventors: Michael Hack, Chun Lin
  • Patent number: 11232941
    Abstract: An electrostatic linear ion trap has first and second axially aligned ion mirrors separated by a charge detection cylinder axially aligned with each ion mirror. Electric fields are selectively established within the first and second ion mirrors in a manner which causes an ion in the trap to oscillate back and forth through the charge detection cylinder between the first and second ion mirrors with a duty cycle, corresponding to a ratio of time spent by the ion passing through the charge detection cylinder and total time spent traversing a combination of the first and second ion mirrors and the charge detection cylinder during one complete oscillation cycle, of approximately 50%.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: January 25, 2022
    Assignee: The Trustees Of Indiana University
    Inventors: Martin F. Jarrold, Joanna A. Hogan
  • Patent number: 11234018
    Abstract: The image decoding method according to the present invention comprises the steps of: determining the availability of a block adjacent to a current block; configuring a merge candidate list for the current block on the basis of the result of the determined availability; and performing motion compensation for the current block on the basis of the merge candidate list, wherein the step of determining availability comprises the steps of inducing block availability information on the adjacent block and inducing the availability of motion information on the adjacent block, and the step of determining the availability of the adjacent block is such that when there is more than one adjacent block, the availability of adjacent blocks can be determined in accordance with a predetermined order restriction.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: January 25, 2022
    Assignees: Electronics and Telecommunications Research Institute, University-Industry Cooperation Group of Kyung Hee University
    Inventors: Hui Yong Kim, Sung Chang Lim, Jin Soo Choi, Jin woong Kim, Gwang Hoon Park, Kyung Yong Kim
  • Patent number: 11230701
    Abstract: Provided are a novel hemagglutinin that can remove cells deviated from the undifferentiated state, the cells being cells that emerge in a colony during culture of stem cells having pluripotency, and a novel method for culturing stem cells having pluripotency, the method using hemagglutinin. Provided is a mutant hemagglutinin complex protein derived from Clostridium botulinum type B, the complex protein containing at least subcomponents HA2 and HA3 of hemagglutinin derived from Clostridium botulinum type B, and the complex protein containing amino acids constituting a glycosylation site, with at least one of the amino acids having been mutated. Provided is a method for culturing stem cells having pluripotency, the method including culturing the stem cell having pluriopotency in the presence of a mutant hemagglutinin complex protein of the present disclosure.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: January 25, 2022
    Assignee: Osaka University
    Inventors: Masahiro Kinooka, Meehae Kim, Yukako Fujinaga, Yo Sugawara
  • Patent number: 11229533
    Abstract: Various embodiments of the present invention generally relate to prosthetic partial finger designs that can mimic the last two joints of the finger. Some embodiments include a proximal phalange, a distal phalange coupled to the proximal phalange, and a knuckle track (e.g., formed in an arc). The knuckle track can be moveably coupled to the proximal phalange an may include multiple teeth formed on which the proximal phalange slides along. A ratcheting mechanism can contact the multiple teeth to allow sliding in only a first direction while the ratcheting mechanism is engaged. Some embodiments include a release mechanism (e.g., a button) configured to disengage the ratcheting mechanism from the multiple teeth to allow the distal phalange to slide in a second direction. In some embodiments, the device may include a spring-back capability that automatically extends the finger after reaching full finger flexion, enabling one-handed use.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: January 25, 2022
    Assignee: The Regents of the University of Colorado
    Inventors: Jacob Segil, Stephen Huddle, Levin Sliker, Richard Weir
  • Publication number: 20220016409
    Abstract: A sterilizable connector may include a sterilization fluid reservoir to provide a sterilization fluid. The sterilizable connector may include a connector. The connector may include a first end to receive a first tube to connect to a medical device (e.g., directly or via one or more intervening components). The connector may include a second end to receive a second tube to connect to a patient (e.g., directly or via one or more intervening components). The connector may include a body to couple the first end to the second end to enable fluid transfer between the first tube and the second tube. The connector may include a body opening to couple to the sterilization fluid reservoir. The sterilizable connector may include a sterilization fluid injector to inject the sterilization fluid from the sterilization fluid reservoir to the connector.
    Type: Application
    Filed: October 29, 2019
    Publication date: January 20, 2022
    Applicant: The Johns Hopkins University
    Inventors: Sarah LEE, James QIN, Anna Claire BAILEY, Eugene OH, Tejasvi DESAI, Giang HOANG, Dylan HIRSCH, Hallie HORVATH
  • Publication number: 20220017235
    Abstract: An autonomous landing system for vertical landing aircraft includes a vertical landing aircraft including a powertrain and an onboard camera, a motion-stabilized visual cue including a visual indicator, wherein the visual cue is configured to maintain a fixed orientation of the visual indicator with respect to a horizon, and an autonomous control system configured to control a position of the aircraft with respect to the visual indicator of the visual cue based on image data captured by the onboard camera.
    Type: Application
    Filed: February 19, 2021
    Publication date: January 20, 2022
    Applicant: The Texas A&M University System
    Inventors: Bochan Lee, Moble Benedict
  • Publication number: 20220015651
    Abstract: An apparatus for and a method for estimating blood pressure are provided. The apparatus for estimating blood pressure includes: a sensor configured to measure a pulse wave signal from an object; and a processor configured to obtain a mean arterial pressure (MAP) based on the pulse wave signal, configured to classify a phase of the obtained MAP according to at least one classification criterion, and to obtain a systolic blood pressure (SBP) by using an estimation model corresponding to the classified phase of the MAP among estimation models corresponding to respective phases of the MAP.
    Type: Application
    Filed: November 13, 2020
    Publication date: January 20, 2022
    Applicants: SAMSUNG ELECTRONICS CO., LTD., IUCF-HYU (Industry-University Cooperation Foundation Hanyang University)
    Inventors: Sang Kon Bae, Joon-Hyuk Chang, Chang Mok Choi, Youn Ho Kim, Jin Woo Choi, Jehyun Kyung, Tae-Jun Park, Joon-Young Yang, Inmo Yeon
  • Publication number: 20220017788
    Abstract: A pressure sensitive adhesive construct comprising: (A) a backing substrate; and (B) a pressure sensitive adhesive composition disposed on the backing substrate, wherein the pressure sensitive adhesive composition includes an ultraviolet radiation-cured polymer made from: (a) at least one epoxidized plant oil, at least one epoxidized animal fat, or a mixture thereof; (b) at least one dicarboxylic acid, at least one polycarboxylic acid, or a mixture thereof; and (c) at least one compound that contains both one carbon-carbon double bond (C?C) and at least one carboxylic acid group.
    Type: Application
    Filed: November 18, 2019
    Publication date: January 20, 2022
    Applicant: Oregon State University
    Inventors: Kaichang Li, Anlong Li
  • Publication number: 20220017998
    Abstract: The method of producing composite material with a high complex of mechanical properties, consisting of vanadium alloy inner layer V—3-11 wt % Ti—3-6 wt % Cr and two outer layers of stainless steel of ferritic grade with chromium content of not less than 13 wt %, includes preparation of a composite workpiece consisting of said inner layer and outer layers, hot treatment by pressure and subsequent exposure in furnace. Prepared composite workpiece, thickness of inner layer of which is 1.5-2 times more than total thickness of outer layers of stainless steel, hot working is performed with pressure of the workpiece in the temperature range of 1,050-1,150° C. with degree of reduction from 30 to 40% and with subsequent exposure for 1-3 hours with temperature reduction to 500-700° C., then annealing workpiece by heating to temperature of 850-950° C., holding for 2-4 hours and subsequent cooling in furnace.
    Type: Application
    Filed: December 13, 2019
    Publication date: January 20, 2022
    Applicant: National University of Science and Technology MISIS
    Inventors: Sergey Anatol'evich NIKULIN, Andrey Borisovich ROZHNOV, Stanislav Olegovich ROGACHEV, Vladislav Alekseevich BELOV, Tat'yana Anatol'evna NECHAYKINA, Vladimir Markovich KHATKEVICH, Aleksandra Pavlovna BARANOVA
  • Publication number: 20220016600
    Abstract: Solid phase extraction (SPE) sorbents and liquid chromatography (LC) stationary phases are provided, as well as methods of fabricating the same. The SPE sorbents and LC stationary phases can use microcrystalline cellulose particles as the substrate and sol-gel sorbent coating technology as the polymer/sorbent immobilization technology. The SPE sorbents and LC stationary phases are stable in a pH range of 1-13 and at a temperature of up to 350 ° C.
    Type: Application
    Filed: September 3, 2021
    Publication date: January 20, 2022
    Applicant: The Florida International University Board of Trustees
    Inventors: Abuzar Kabir, Kenneth G. Furton