Abstract: The present disclosure relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present disclosure relates to cancer markers as diagnostic markers and clinical targets for lung cancer.

Abstract: Methods and devices are provided for error correction of distributed data in distributed systems using Reed-Solomon codes. In one embodiment, processes are provided for error correction that include receiving a first correction code for data fragments stored in storage nodes, constructing a second correction code responsive to an unavailable storage node of the storage nodes, performing erasure repair of the unavailable storage node, and outputting a corrected data fragment. The first correction code is a Reed-Solomon code represented as a polynomial and the second correction code is represented as a second polynomial with an increased subpacketization size. Processes are configured to account for repair bandwidth and sub-packetization size. Code constructions and repair schemes accommodate different sizes of evaluation points and provide a flexible tradeoff between the subpacketization size repair bandwidth of codes.

Abstract: A power converter and method for providing surge protection to the power converter is provided herein. An over voltage protection portion of a protection circuit is coupled between the rail voltage and ground reference of the power converter, and senses a first magnitude of the rail voltage. An under voltage protection portion of the protection circuit is coupled to a controller of the power converter and further between the rail voltage and the ground reference, and senses a second magnitude of the rail voltage to be transmitted to the controller. A regulator block is coupled between the over voltage protection portion and the under voltage protection portion, and is configured to compare the first magnitude of the rail voltage to a reference voltage of the regulator block, and to short circuit the under voltage protection portion when the first magnitude of the rail voltage is greater than the reference voltage.

Abstract: Provided is a method for setting an edge blur according to a brightness value including a first step for providing a plurality of target sheets on each of which a reference pattern for detecting a reference line and a grid pattern for detecting an edge position are provided, and in which changes in brightness values included in the grid patterns are different from each other, a second step for capturing images of the target sheets to obtain target sheet images, a third step for analyzing a reference pattern for each corresponding target sheet to estimate the reference line, and analyzing the grid pattern to extract an edge profile provided in the grid pattern, a fourth step for calculating a gradient of a brightness difference between adjacent pixels on the basis of the edge profile, and acquiring a background edge blur parameter and a foreground edge blur parameter on the basis of the gradient according to brightness contrast present in the image, and a fifth step for generating background edge blur predicti

Abstract: Provided are apparatus and methods for generating a representation of a physical environment, comprising: a mobile sensor platform (MSP) including sensors that output sensor signals relating to parameters such as range, gravity, direction of the Earth's magnetic field, and angular velocity. The MSP is adapted to be moved through the environment. The sensor signals are processed and observations of axes in the environment are generated for a sequence of time steps, the orientation of the MSP is estimated for each of the time steps, observed axes are identified at each orientation, and similar axes are associated. The orientations, the axes in the environment, and the directions of gravity and the Earth's magnetic field are linked such that each observation is predicted based on the estimates of the orientations. An estimate of the orientations is optimized and an output of the representation of the physical environment is generated based on the optimized orientation estimates.

Abstract: A graphic arts support assembly is operable to be used with a graphic arts plate assembly in a press. The graphic arts support assembly and the plate assembly are configured for removable association with a lift mechanism including a shiftable lift element. The support assembly includes a graphic arts magnetic support structure operable to removably support the graphic arts plate assembly. The magnetic support structure includes a support plate, a magnet fixed relative to the plate, and an alignment element projecting from the support plate. The support assembly is operable to be mounted on the lift mechanism so that the lift element is aligned with a lift opening of the support plate, with the lift element shiftable through the lift opening to locate at least part of the graphic arts plate assembly away from the support plate.

Abstract: A wide-beam planar backfire and bidirectional circularly-polarized antenna. An entire planar sectorial magnetic dipole is of a semi-closed structure, the planar sectorial magnetic dipole comprises two identical sectorial patches and a vertical short-circuit wall, and the vertical short-circuit wall is connected with straight sides of the two sectorial patches along a radial direction of the planar sectorial magnetic dipole; two sets of concentric annular electric dipoles are respectively used as a top concentric annular radiating element and a bottom concentric annular radiating element, as well as a top concentric annular reflector and a bottom anti-concentric annular reflector; and the top concentric annular radiating element is connected with an upper surface of the planar sectorial magnetic dipole through a top connecting branch, and the bottom concentric annular radiating element is connected with a lower surface of the planar sectorial magnetic dipole through a bottom connecting branch.

Abstract: Mithramycin side chain carboxylic acid (MTM-SA) derivative are provided, which include a substituted amino acid derivative, a substituted amino acid dipeptide derivative, or an unsubstituted dipeptide derivative. The MTM-SA derivatives are useful for treatment of cancer or neuro-diseases associated with an aberrant erythroblast transformation-specific transcription factor. Unique MTM-SA derivatives have increased selectively toward ETS transcription factor.

Abstract: A human negligence warning method based on augmented reality includes steps of: using a smart wearable device to photograph multiple physical operation elements of an electronic apparatus to obtain interface depth data; performing spatial position calculations according to the interface depth data, to set corresponding wrapping geometry elements between the physical operation elements and the smart wearable device to wrap the physical operation elements, respectively; photograph a hand of a wearer wearing the smart wearable device to obtain a gesture and a spatial position of the hand; and judging whether the hand touches one of the wrapping geometry elements according to the gesture and the spatial position, and further judging whether a corresponding procedure to be initiated by the physical operation element is correct if yes, If the corresponding procedure is not correct, then an warning operation is performed to avoid human negligence.

Abstract: Luminescent solar concentrators in accordance with various embodiments of the invention can be designed to minimize photon thermalization losses and incomplete light trapping using various components and techniques. Cadmium selenide core, cadmium sulfide shell (CdSe/CdS) quantum dot (“QD”) technology can be implemented in such devices to allow for near-unity QDs and sufficiently large Stokes shifts. Many embodiments of the invention include a luminescent solar concentrator that incorporates CdSe/CdS quantum dot luminophores. In further embodiments, anisotropic luminophore emission can be implemented through metasurface/plasmonic antenna coupling. In several embodiments, red-shifted luminophores are implemented. Additionally, top and bottom spectrally-selective filters, such as but not limited to selectively-reflective metasurface mirrors and polymeric stack filters, can be implemented to enhance the photon collection efficiency.

Abstract: Disclosed herein are therapeutic constructs including a delivery particle, at least one mitotic kinase inhibitor, and at least one immune checkpoint inhibitor. Also disclosed are therapeutic constructs including a mitotic kinase inhibitor, an immune checkpoint inhibitor, and a chemical linker. These therapeutic constructs cause cancer death by both therapeutic and immune effects and promote targeted delivery of more therapeutics to the surviving cancer cells in a positive feed-back loop. They enhance therapeutic index of free drugs and can be used intratumorally or systemically. This strategy can treat broad cancer types and is particular useful for cancer without obvious receptors for cancer-targeted delivery of otherwise toxic therapeutics.

Abstract: A knowledge model “overlay” for organizing and analyzing large, dynamic data volumes is implemented as a hypergraph that manifests as a result of a distributed theory-driven data source transformation process. This process maps exponentially growing data into an asymptotically limited information space. Within this space, real-world entities (e.g. people, computers, cities, Earth) and their complex interdependencies (e.g. social networks, connectivity, causal relationships) are represented as attributed hypergraph elements (i.e. both hypervertices and hyperedges). Attributes are represented as state vectors affixed to any hypergraph element. Transformation of source system data into this overlay structure is accomplished with minimal data movement and replication using a universal “pointer” like mechanism that is managed in a decentralized fashion by the respective transformation components.

Abstract: A method of using data-driven predictive modeling to predict and classify battery cells by lifetime is provided that includes collecting a training dataset by cycling battery cells between a voltage V1 and a voltage V2, continuously measuring battery cell voltage, current, can temperature, and internal resistance during cycling, generating a discharge voltage curve for each cell that is dependent on a discharge capacity for a given cycle, calculating, using data from the discharge voltage curve, a cycle-to-cycle evolution of cell charge to output a cell voltage versus charge curve Q(V), generating transformations of ?Q(V), generating transformations of data streams that include capacity, temperature and internal resistance, applying a machine learning model to determine a combination of a subset of the transformations to predict cell operation characteristics, and applying the machine learning model to output the predicted battery operation characteristics.

Abstract: Residuals, such as slag particles, from iron- and/or steel-making, and/or water-leached eluates thereof, are added directly to a conventional or multi-staged anaerobic digester or other sewage sludge or biosolid handling process. The slag particles or other residuals sorb, sequester, immobilize, or otherwise promote the removal of phosphorus and/or sulfur from wastewater, sludge, or biosolids being treated, such that the associated aqueous phase concentrations of phosphorus and sulfur are significantly reduced.

Abstract: Methods and systems are described for digitally reconstructing an unknown 3D structure of a target molecule using orthogonal extension. A plurality of 2D images of the target molecule are captured by an imaging system. An estimated low-order moment of the unknown 3D structure (e.g., a covariance matrix) is calculated based on the 2D images. A homologous molecule having a known 3D structure is identified and at least one expansion coefficient of the known structure of the homologous molecule is determined. At least one estimated expansion coefficient for the unknown structure is calculated based at least in part on the estimated low order moment of the unknown structure and the at least one expansion coefficient of the known structure. An estimated 3D reconstruction of the target molecule is then generated based on the at least one estimated expansion coefficient for the unknown structure of the target molecule.

Abstract: Disclosed herein are methods and compositions for preserving avulsed teeth and/or explanted tissue. The disclosed methods for preserving avulsed teeth and/or explanted tissue typically include placing the avulsed teeth and/or explanted tissue in a preservation solution comprising at least about 2.75 g/L sugar. Suitable explanted tissues for the disclosed methods may include explanted tissues comprising fibroblasts, such as dental tissue and/or oral tissue. The preservation solution of the disclosed preservation methods may include additional components which may include but are not limited to inorganic salts, amino acids, vitamins, and buffering agents. The preservation solution may be prepared from a powder formulation having a long shelf-life.

Abstract: Described herein are systems and methods for ensuring plasma homogeneity in a discharge cell. The discharge cell may include a first hollow electrode and a second hollow electrode spaced away from the first electrode to define a discharge gap therebetween. A fluid inlet port may in fluid communication with an internal bore of the first electrode. A fluid outlet port may be in fluid communication with the discharge gap. A first pair of viewports may define a first optic pathway through the discharge gap. A second pair of viewports may define a second optic pathway through the discharge gap. A third pair of viewports may define a third optic pathway through the discharge gap, the third optic pathway defined through the hollow interior of the first and second electrodes.

Abstract: A method for producing insoluble sulfur, including: heating a sulfur to 200-700° C., quenching it with water, aqueous solution and other solvents, drying and solidifying the resulting substance at 40-80° C. for 3-15 h, to obtain an insoluble sulfur crude product; crushing the crude product in water into particles with a particle size of 50-400 meshes, wherein the water temperature is not higher than 80° C.; pumping the slurry of water and crude product into the upper part of an extraction column, pumping solvent into the lower part thereof; making the water and solvent from the top of the column flow into a separation tank to separate water phase and solvent phase, heating and evaporating the solvent phase to recover solvent and obtain soluble sulfur; heating and evaporating the insoluble sulfur and solvent from the bottom of the column to recover solvent and obtain purified insoluble sulfur.

Abstract: Provided is a drainage grouting pipe and a method of use thereof. The drainage grouting pipe comprises a perforated steel pipe, a plurality of elastic anti-filtration geotextiles, a movable stopper, and a grouting pipe. The perforated steel pipe consists of a front conical tip, a middle grouting section, a rear hole-free section, and a steel pipe seal. The middle grouting section is provided with a plurality of grouting holes. The surface of the middle grouting section of the perforated steel pipe is seamlessly, and circumferentially wrapped by the plurality of elastic anti-filtration geotextiles, and gaps are formed between adjacent elastic anti-filtration geotextiles. Firstly, the geotechnical layer is drained by a pumping system, and then the grouting position in the geotechnical layer is located and controlled by pulling out the grouting pipe to control the plunging depth of the movable stopper, thus achieving the prevention and treatment of groundwater seepage damage.

Abstract: An apparatus including direct-current (DC)-alternating-current (AC) inverter circuitry, first and second circuits, and output circuitry. The DC-AC inverter circuitry inverts a DC input signal corresponding to an input voltage to an AC signal. The first circuit and second circuits respectively include inductive isolation circuits driven in response to power from the at least one AC signal, and rectifier circuits that responds to the inductive isolation circuits by outputting first and second rectified signals, where at least one of the first and second rectifier circuits characterized as being limited by a voltage breakdown rating. The output circuitry provides a DC output voltage signal and to cascade a plurality of signals, including the first and second rectified signals, to provide a voltage source that is dependent on the first and second rectified signals and greater than voltage breakdown rating.