Patents Assigned to University
  • Patent number: 10989695
    Abstract: Disclosed are an online monitoring system for a crack on a hoist spindle and an operation method thereof. The system comprises: a rope power part, a crack detection part, a wireless transmission part, and a computer. The rope power part comprises two traction ropes, two guide wheels, two stepper motors, and two stepper motor drivers. The crack detection part comprises a spiral tube guide rail, a sliding body, and an ultrasonic generator. The wireless transmission part comprises three zigbee wireless sensing modules. The zigbee wireless sensing modules receive instructions from the computer and transmit the instructions to the stepper motor drivers to control the motors to rotate. The stepper motors drive the guide wheels to rotate to realize the winding of the ropes, so as to pull the sliding body to slide on the spiral tube guide rail. The ultrasonic generator clamped on the sliding body monitors the rotating spindle along the spiral tube guide rail.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: April 27, 2021
    Assignee: China University of Mining and Technology
    Inventors: Zhencai Zhu, Hao Lu, Shuang Cao, Yuxing Peng, Gongbo Zhou, Guohua Cao, Gang Shen, Wei Li, Dagang Wang, Fan Jiang
  • Patent number: 10987657
    Abstract: A catalyst comprising Y2O3 nanorods and gold nanoparticles dispersed on a surface of the nanorods is provided. The gold is present at a concentration of 0.5-2 wt %. A method of forming olefins by oxidative cracking is also provided. The method includes reacting an alkane with a reactant gas mixture in the presence of a catalyst under conditions suitable for forming light olefins (ethtylene and propylene).
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: April 27, 2021
    Assignee: King Abdulaziz University
    Inventors: Katabathini Narasimharao, Abdulmohsen Ali Alshehri
  • Patent number: 10991836
    Abstract: A semiconductor device and method for fabricating same is disclosed. Embodiments are directed to a semiconductor device and fabrication of same which include a polycrystalline or amorphous substrate. An electrically conductive Ion Beam-Assisted Deposition (IBAD) template layer is positioned above the substrate. At least one electrically conductive hetero-epitaxial buffer layer is positioned above the IBAD template layer. The at least one buffer layer has a resistivity of less than 100 ??cm. The semiconductor device and method foster the use of bottom electrodes thereby avoiding complex and expensive lithography processes.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: April 27, 2021
    Assignee: University of Houston System
    Inventor: Venkat Selvamanickam
  • Patent number: 10988506
    Abstract: Cyclic tetrapeptide stereochemical isomers of CJ-15,208, pharmaceutical compositions from such cyclic tetrapeptides, and methods of using such pharmaceutical compositions. The cyclic tetrapeptide compounds and pharmaceutical compositions disclosed herein are potent analgesics active in several pain models with generally minimal tolerance and reduced likelihood to induce addiction relative to other known opiates.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: April 27, 2021
    Assignee: University of Kansas
    Inventors: Jane V. Aldrich, S P Sanjeewa Nilendra Senadheera
  • Patent number: 10988519
    Abstract: Provided herein is a recombinant viral vector having packaged therein an expression cassette comprising an engineered complement regulator factor H (fH), wherein the gene encodes a hfH protein variant comprising short consensus repeats (SCRs) 1-4, 6-8, and 17-20. Pharmaceutical compositions containing this vector and plasmids comprising nucleic acid sequences that encode the fH protein variant are also provided.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: April 27, 2021
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Wenchao Song, Damodar Gullipalli, Takashi Miwa
  • Patent number: 10989751
    Abstract: A sparse voltage measurement-based fault location determination system and method for an alternating current (AC) distribution network is described. This method can use sparse voltage measurements and Bayesian compressive sensing (BCS) algorithm to reconstruct a sparse current vector. A fault location is then determined based on the reconstructed sparse current vector. The disclosed method provides robust fault location results under a variety of asymmetrical fault scenarios. Fewer intelligent electronic devices (IEDs) allocated in the terminal buses are needed for determining the fault location; therefore, this implementation is relatively cost effective.
    Type: Grant
    Filed: October 27, 2020
    Date of Patent: April 27, 2021
    Assignee: North China Electric Power University
    Inventors: Ke Jia, Tianshu Bi, Bin Yang, Hao Liu
  • Patent number: 10988748
    Abstract: Polypeptides, and methods for their use, are disclosed that have an amino acid sequence at least 75% identical to the amino acid sequence of SEQ ID NO:1, are provided, wherein (a) the polypeptide degrades a PFQPQLPY (SEQ ID NO: 140) peptide and/or a PFPQPQQPF (SEQ ID NO: 68) at pH 4; (b) residue 467 is Ser, residue 267 is Glu, and residue 271 is Asp; and (c) the polypeptide comprises an amino acid change from SEQ ID NO: 1 at one or more residues selected from the group consisting of 221, 262E, 268, 269, 270, 319A, 320, 354E/Q/R/Y, 358S/Q/T, 368F/Q, 399, 402, 406, 424, 449, 461, 463, 105, 171, 172, 173, 174, and 456.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: April 27, 2021
    Assignees: University of Washington, The Regents of the University of California
    Inventors: Ingrid Swanson Pultz, Clancey Wolf, Justin Bloomfield Siegel, Christine Elaine Tinberg, Lance Stewart, David Baker
  • Patent number: 10988729
    Abstract: Described herein are compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation and/or regulated expression of one or more antigens of interest.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: April 27, 2021
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Roy Curtiss, III, Shifeng Wang
  • Patent number: 10989756
    Abstract: The disclosure provides for systems and methods which utilize an optical scattering microscope with a spatiotemporal approach to measure the nature and extent of energy flow across electronic or semiconductor materials.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: April 27, 2021
    Assignee: The Regents of the University of California
    Inventors: Naomi S. Ginsberg, Milan Edouard Delor
  • Patent number: 10986983
    Abstract: A stereo-imaging device that operates by translating a single lens in front of an exposed imaging sensor, or translating one of the objective lens group for higher image quality. The device and method is used as a surgical instrument guide. An objective lens with a translating lens part can directly attached in front of a camera with an exposed sensor or an endoscopic circuit with an exposed imaging fiber bundle surface to capture/record the image shift generated by the lens translation. The stereo-imaging device can realize a camera which can swing back and forth from regular 2D image capturing mode to the stereo mode to capture images for 3D viewing, or a switchable stereo endoscope without size increases of multiple imaging systems to be used for periodical 3D inspections.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: April 27, 2021
    Assignees: The Regents of the University of California, Optech Ventures, LLC
    Inventors: Wook Choi, Vladimir Rubtsov, Chang-Jin Kim, Gennady Sigal
  • Patent number: 10987433
    Abstract: A nucleic acid trans-splicing molecule is provided that can replace an exon in a targeted mammalian ocular gene carrying a defect or mutation causing an ocular disease with an exon having the naturally-occurring sequence without the defect or mutation. A method of treating an ocular disease, e.g., Stargardt's Disease, caused by a defect or mutation in a target gene, e.g., ABCA4 comprising: administering to the ocular cells of a subject having an ocular disease a composition comprising a recombinant AAV comprising a nucleic acid trans-splicing molecule as described above.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: April 27, 2021
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Jean Bennett, Jeannette Bennicelli, Scott J. Dooley, Lloyd G. Mitchell
  • Patent number: 10989308
    Abstract: A sealing device with convertible magnetic sealing medium includes a housing with an accommodation cavity formed therein, a rotary shaft rotatably disposed in the accommodation cavity, a first pole piece disposed on the rotary shaft, a second pole piece fitted over the rotary shaft, and a permanent magnet fitted over the rotary shaft between the first pole piece and the second pole piece. The rotary shaft has a first blind hole, a second blind hole, a first via hole and a second via hole. A plurality of first pole teeth are provided in an inner circumferential wall of the first pole piece and a plurality of second pole teeth are provided in an inner circumferential wall of the second pole piece. Magnetic powder is provided between a top surface of each of the first and second pole tooth and the outer circumferential surface of the rotary shaft.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: April 27, 2021
    Assignee: Tsinghua University
    Inventors: Decai Li, Zhenghao Li
  • Patent number: 10989867
    Abstract: A fiber-based sensor and a method of forming a fiber-based sensor using microsphere lithography techniques in which a microsphere array is applied to a surface of a tip of an optical fiber to provide for microsphere lithography fabrication of a desired pattern on the tip of the optical fiber. The characteristics of the pattern define sensing capabilities of the sensor to provide for chemical and/or biological sensing.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: April 27, 2021
    Assignee: The Curators of the University of Missouri
    Inventors: Edward C. Kinzel, Mahmoud Almasri, Chuang Qu, Ibrahem Jasim, Jiayu Liu
  • Patent number: 10987598
    Abstract: A method in accordance with present embodiments includes receiving a signal that a vehicle is positioned on a motion base system; and actuating a plurality of motion bases of the motion base system to actuate independently of one another to cause the vehicle to roll, pitch, or heave. Actuating the plurality of motion bases includes providing a first signal to an electrical actuator associated with a first motion base; actuating a movable deck of the first motion base to move a first distance relative to its housing at a first time point; providing a second signal to an electrical actuator associated with a second motion base; and actuating a movable deck of the second motion base to move a second distance relative to its housing at the first time point.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: April 27, 2021
    Assignee: Universal City Studios LLC
    Inventors: Ted W. Van Winkle, Paula Stenzler, Steven C. Blum
  • Patent number: 10987375
    Abstract: Novel hydrogels that can serve as 3D hypoxic microenvironments are disclosed. Oxygen controllable, hypoxia-inducible hydrogels (HI hydrogels) are composed of a phenolic agent and polymer backbone, which can form hydrogel networks via oxygen consumption in an enzyme-mediated crosslinking reaction. The HI hydrogels are degradable, cytocompatible, and have tunable mechanical properties. Oxygen levels and gradients within the HI hydrogels are controlled and precisely predicted. As a result, the HI hydrogels induce prolonged hypoxic conditions. The HI hydrogels guide vascular morphogenesis in vitro by activating hypoxia-inducible factors and promote neovascularization from tissue, as well as stimulate tissue in dynamic in vivo environments. The HI hydrogels are a new class of biomaterials that are useful in many applications, ranging from the engineering of de novo tissues and disease models to the treatment of vascular disorders.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: April 27, 2021
    Assignee: The Johns Hopkins University
    Inventors: Sharon Gerecht, Kyung Min Park
  • Patent number: 10988489
    Abstract: Disclosed are novel organoborane compositions of Formula (I), (II) or (III), wherein R1, R2, R3, R?, R?, n, n?, n?, m, m?, and m? are defined hereinabove. Also disclosed is a method of using said compositions for electrolytic media in lithium rechargeable batteries, including lithium-ion or lithium-air rechargeable batteries. Also disclosed are compositions containing said Formula (I), (II) and (III) compounds with lithium salts, useful as electrolytic media or matrices.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: April 27, 2021
    Assignee: Clark Atlanta University
    Inventors: Ishrat Khan, Ahmed Alzharani, Amal Al-abdulrahman, Rasha Alshahrani
  • Patent number: 10988804
    Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: April 27, 2021
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Stephen R. Quake, Thomas M. Snyder, Hannah Valantine
  • Patent number: 10992291
    Abstract: A true random number generator based on a voltage-controlled oscillator includes a thermal noise generator, a ring oscillator, a voltage-controlled oscillator, a D flip-flop, and a post-processing circuit. The D flip-flop has a clock terminal, an input terminal, and an output terminal. An output terminal of the thermal noise generator is connected with an input terminal of the voltage-controlled oscillator. An output terminal of the voltage-controlled oscillator is connected with the clock terminal of the D flip-flop. An output terminal of the ring oscillator is connected with the input terminal of the D flip-flop. The output terminal of the D flip-flop is connected with an input terminal of the post-processing circuit. An input terminal of the thermal noise generator is connected with a reference level. The thermal noise generator includes a digital-analog converter, an operational amplifier, a first resistor, a second resistor, a third resistor, and a fourth resistor.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: April 27, 2021
    Assignee: Ningbo University
    Inventors: Pengjun Wang, Zhen Li, Gang Li, Huihong Zhang
  • Patent number: 10988347
    Abstract: A large-tonnage coal dropping buffer skip for a mine is disclosed. A loading skip box (14) is installed at the top of a large-tonnage skip (12), a coal dropping buffer device (13) is arranged on the inner sidewall of the large-tonnage skip (12), and the coal dropping buffer device (13) includes: a frame (1) fixedly connected with the inner sidewall of the large-tonnage skip (12); a lining plate guide frame (6) connected with the frame (1) through shock absorbers (2), guide sliding grooves being formed in the lining plate guide frame (6); a lining plate support (4) slidably nested in the guide sliding grooves in the lining plate guide frame (6), hoisting lugs (9) for hoisting being arranged at the top end of the lining plate support (4); and a lining plate (5) detachably connected with the lining plate support (4) through fasteners (7).
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: April 27, 2021
    Assignees: China University of Mining and Technology, XUZHOU COAL MINE SAFETY EQUIPMENT MANUFACTURE CO., LTD.
    Inventors: Yuxing Peng, Zhencai Zhu, Gongbo Zhou, Changhua Hu, Qingyong Du, Hao Lu, Guohua Cao, Songyong Liu, Gang Shen
  • Patent number: 10987315
    Abstract: The present disclosure is directed to antithrombotic nanoparticles and methods of treating necrotizing enterocolitis.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: April 27, 2021
    Assignee: University of South Florida
    Inventors: Akhil Maheshwari, Samuel Wickline, Kopperuncholan Namachivayam, Hua Pan