Patents Assigned to University
  • Three dimensional woven lattices as multi-functional heat exchanger
    Patent number: 10982913
    Abstract: The present invention is directed to devices formed from three dimensional (3D) structures composed of wires, yarns of wires, or 3D printed structures. The devices of the present invention offer the potential for 3D structures with multiple properties optimized concurrently, using optimization within the 3D manufacturing constraints. The 3D structures of the present invention include multiple properties that are optimized for heat transfer applications. The present invention also includes the methods for optimization of the 3D woven lattices as well as methods of use of the 3D woven lattices in heat transfer applications.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: April 20, 2021
    Assignees: The Johns Hopkins University, Saertex USA, LLC
    Inventors: Kevin J. Hemker, Timothy P. Weihs, Stephen Ryan, Longyu Zhao, Seunghyun Ha, Yong Zhang, Sen Lin, James K. Guest, Keith Sharp
  • Methods for conductive adhesives based on graphene and applications thereof
    Patent number: 10982119
    Abstract: The present disclosure relates to conductive adhesives and inks. The disclosed conductive adhesives include glues and epoxies, based on graphene and graphene/carbon composites and the methods of manufacture thereof, such conductive adhesives exhibiting excellent conductivity, thermal properties, durability, low curing temperatures, mechanical flexibility, and reduced environmental impact. Further, adhesives with conductive additives such as silver nanowires and the methods of production thereof are disclosed herein.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: April 20, 2021
    Assignees: The Regents of the University of California, Nanotech Energy, Inc.
    Inventors: Maher F. El-Kady, Nahla Mohamed, Jack Kavanaugh, Richard B. Kaner
  • LRH-1 modulators
    Patent number: 10980755
    Abstract: Disclosed herein are compositions and methods for modulating the liver receptor homolog-1.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: April 20, 2021
    Assignee: The Regents of the University of California
    Inventors: Pamela M. England, Felipe de Jesus Cortez
  • Method of designing and manufacturing freeform surface off-axial imaging system
    Patent number: 10983316
    Abstract: The present disclosure relates to a method of designing a freeform surface off-axial imaging system. The method comprises the steps of establishing an initial system and selecting feature fields; gradually enlarging a construction of feature field, and constructing the initial system into a freeform surface system; and expanding a construction area of each freeform surface of the freeform surface system, and reconstructing the freeform surface in an extended construction area.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: April 20, 2021
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Rui-rui Tang, Ben-qi Zhang, Jun Zhu, Guo-Fan Jin, Shou-Shan Fan
  • Non-invasive diagnosis of graft rejection in organ transplant patients
    Patent number: 10982275
    Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.
    Type: Grant
    Filed: October 8, 2019
    Date of Patent: April 20, 2021
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Stephen R. Quake, Thomas M. Snyder, Hannah Valantine
  • Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
    Patent number: 10982230
    Abstract: The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together, with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: April 20, 2021
    Assignees: The Regents of the University of California, University of Vienna, Emmanuelle Charpentier
    Inventors: Jennifer A. Doudna, Martin Jinek, Krzysztof Chylinski, Emmanuelle Charpentier
  • Method and system for secure encryption
    Patent number: 10985906
    Abstract: A method executed by a computer system that transmits a multimedia content through a negative-base number. The method includes generating a binary sequence for the multimedia content, converting the binary sequence into a negative-base number, receiving the negative-base number, retrieving a negative base of the negative base number, calculating the binary sequence based on the negative-base number and the negative base, and obtaining the multimedia content based on the binary sequence.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: April 20, 2021
    Assignee: Macau University of Science and Technology
    Inventors: Zhanchuan Cai, Ting Lan
  • Fluorinated polymer dots
    Patent number: 10983130
    Abstract: This disclosure provides semiconducting polymer dots (Pdots) for use in a wide variety of applications. In particular, this disclosure provides Pdots that are halogenated, including fluorinated Pdots. This disclosure also provides methods for synthesizing Pdots and methods for using Pdots, such as for biological imaging.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: April 20, 2021
    Assignee: University of Washington Through Its Center for Commercialization
    Inventors: Daniel Chiu, Yong Zhang, Jiangbo Yu, Yu Rong
  • Imaging agents
    Patent number: 10980898
    Abstract: The present disclosure provides imaging agents that are useful for the detection and evaluation of heart conditions, such as myocardial infarction. Upon activation, the imaging agents of the present disclosure may be detected using an ultrasound imaging device.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: April 20, 2021
    Assignee: Drexel University
    Inventors: Steven Wrenn, Brett Angel, Andrew Kohut, Aaron Fafarman, Michael Cimorelli
  • Intelligent sensing system for indoor air quality analytics
    Patent number: 10982869
    Abstract: Existing indoor air quality monitoring technologies focus on measuring which turn out to be effective in increasing people's awareness of air quality. However, the lack of identification of pollution sources is prone to lead to general and monotonous suggestions. In this disclosure, an indoor air quality analytics system is presented that is able to detect pollution events and identify pollution sources in real-time. The system can also forecast personal exposure to air pollution and provide actionable suggestions to help people improve indoor air quality.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: April 20, 2021
    Assignee: Board of Trustees of Michigan State University
    Inventors: Mi Zhang, Biyi Fang, Taiwoo Park
  • Antimicrobial therapy
    Patent number: 10980848
    Abstract: Methods and compositions comprising hogocidin peptides (SH-lantibiotics), derivatives and variants are provided. Also provided are methods and compositions comprising probiotic compositions utilizing strains of S. hominis and S. epidermidis that produce hogocidin, hogocidin-like peptides, or other inhibitors of skin pathogens. Methods of treatment for microbial skin infections and atopic dermatitis are also provided.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: April 20, 2021
    Assignee: The Regents of the University of California
    Inventors: Teruaki Nakatsuji, Richard L. Gallo
  • Piezoelectric resonance controlled terahertz wave modulators
    Patent number: 10985700
    Abstract: Disclosed are various embodiments of a terahertz wave modulator. The wave modulator can include one or more layers of piezoelectric/ferroelectric single crystal or polycrystalline material. The crystalline material can be configured to resonate when a low-energy external excitation is applied. An incident terahertz waveform can be dynamically controlled when the incident terahertz waveform interacts with the at least one layer of piezoelectric crystalline material while the at least one layer of piezoelectric crystalline material is resonating. The dynamic control of the incident terahertz waveform can be with respect to at least one of a phase shift and an amplitude modulation of the waveform.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: April 20, 2021
    Assignee: Board of Regents, The University of Texas System
    Inventors: Moumita Dutta, Ruyan Guo, Amar Bhalla, Soutik Betal
  • Method and device for inducing motion information between temporal points of sub prediction unit
    Patent number: 10986359
    Abstract: According to the present invention, there is provided A method of encoding a three-dimensional (3D) image, the method comprising: determining a prediction mode for a current block as an inter prediction mode; determining whether a reference block corresponding to the current block in a reference picture has motion information; when the reference block has the motion information, deriving motion information on the current block for each sub prediction block in the current block; and deriving a prediction sample for the current block based on the motion information on the current block.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: April 20, 2021
    Assignee: University-Industry Cooperation Group of Kyung Hee University
    Inventors: Gwang Hoon Park, Min Seong Lee, Young Su Heo, Yoon Jin Lee
  • Reversal of fosfomycin resistance
    Patent number: 10980811
    Abstract: Compounds, pharmaceutical compositions, and methods for reversing fosfomycin resistance are disclosed. Embodiments of the disclosed compounds inhibit fosfomycin-inhibiting enzymes. Some embodiments of the compounds are FosA inhibitors. The disclosed pharmaceutical compositions include (i) fosfomycin or a pharmaceutically acceptable salt thereof and (ii) a compound, or a pharmaceutically acceptable salt thereof, which inhibits a fosfomycin-inhibiting enzyme. A method of inhibiting growth of a fosfomycin-resistant bacterium includes contacting the bacterium with (i) fosfomycin or a pharmaceutically acceptable salt thereof and (ii) an effective amount of a disclosed compound or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: April 20, 2021
    Assignees: University of Pittsburgh—of the Commonwealth System of Higher Education, University of Maryland, Baltimore
    Inventors: Nicolas Paul Sluis-Cremer, Adam Daniel Tomich, Yohei Doi, Eric J. Sundberg, Erik H. Klontz, Steven Fletcher
  • Chlamydomonas mutants produced using RGEN RNP and method for preparing pigment using the same
    Patent number: 10980252
    Abstract: A new alga having an improved ability to produce a pigment is disclosed. When the alga is used, a carotenoid-based pigment, specifically, a xanthophyll can be produced by consuming less energy, so that it is possible to efficiently produce the pigment at the industrial level. The pigment can be applied as a raw material for a food, a health functional food and a medicine, which include the pigment. Since a DNA fragment is not likely to be inserted into a target base sequence or a base sequence other than the target, it is expected that the procedure of constructing the mutant is not regulated as a GMO.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: April 20, 2021
    Assignee: Industry-University Cooperation Foundation Hanyang University
    Inventors: Eon Seon Jin, Sang Su Bae, Kwang Ryul Baek, Duk Hyoung Kim, Joo Yeon Jeong
  • Proteins comprising MRSA Pbp2a and fragments thereof, nucleic acids encoding the same, and compositions and their use to prevent and treat MRSA infections
    Patent number: 10980870
    Abstract: Nucleic acid molecules which encode an MRSA PBP2a protein or a fragment thereof which comprises at least 245 amino acid are disclosed. Compositions comprising the nucleic acid molecules are disclosed. Novel proteins which comprise a MRSA PBP2a protein or a fragment thereof which comprises at least 245 amino acid are disclosed are disclosed. Methods of inducing an immune response against MRSA PBP2a are disclosed, as are methods of treating an individual who has been diagnosed with MRSA and methods of preventing MRSA infection in an individual.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: April 20, 2021
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: David B. Weiner, Matthew P. Morrow
  • Thermoreversible polymers and methods of use thereof
    Patent number: 10982055
    Abstract: The present disclosure provides thermoreversible polymers, hydrogel compositions comprising the thermoreversible polymers, as well as methods of making and using the thermoreversible polymers.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: April 20, 2021
    Assignee: The Regents of the University of California
    Inventors: Christina Marie Fuentes, Barbara L. Ekerdt, David V. Schaffer, Rachel Segalman, Yuguo Lei
  • Physical random access channel scheme for wireless networks using an analog bloom filter
    Patent number: 10986669
    Abstract: This disclosure describes a novel PRACH scheme based on an Analog Bloom Filter, in which user equipment is allowed to transmit multiple sequences to a base station, instead of only one sequence as is the case with the current LTE. A new decoding algorithm is disclosed, which copes with the unique challenges in the signal generated with ZC sequences, such as peak shifting and multiple peaks. In addition, when CFO can be removed the new scheme allows the UE to piggyback log 2 ? ? 7 bits of information along with the signal. Evaluation shows that the new scheme outperforms the existing PRACH of LTE by more than an order of magnitude in many cases, and therefore is a good candidate as the PRACH for future wireless networks (e.g., 5G).
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: April 20, 2021
    Assignee: The Florida State University Research Foundation, Inc.
    Inventor: Zhenghao Zhang
  • Methods of determining whether anti-PACAP antibodies inhibit PACAP-associated photophobia or light aversion
    Patent number: 10981984
    Abstract: This invention relates to methods of screening for anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof, for potential use in treating or preventing PACAP-associated photophobia or light aversion, and therapeutic compositions containing and methods of using anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: April 20, 2021
    Assignees: H. LUNDBECK A/S, The University of Iowa Research Foundation
    Inventors: Adisa Kuburas, Bianca Mason, Levi P. Sowers, Andrew F. Russo, Maria-Cristina Loomis, Leon F. Garcia-Martinez, Benjamin H. Dutzar, Daniel S. Allison, Katherine Lee Hendricks, Ethan W. Ojala, Pei Fan, Jeffrey T. L. Smith, John A. Latham, Charlie Karasek, Jenny Mulligan, Michelle Scalley-Kim, Erica Stewart, Vanessa Lisbeth Rubin, Jens J. Billgren
  • Nucleic acid catenane with a linking duplex biosensor for detection of a microorganism target
    Patent number: 10982253
    Abstract: The present application is directed to biosensors and methods for detecting a microorganism target in a sample using a mechanically interlocked nucleic acid catanane, wherein an enzyme from the microorganism target or that is activated by a molecule from the microorganism target cleaves a linkage in a first single-stranded nucleic acid ring of the catanane structure, allowing rolling-circle amplification to occur and the presence of rolling-circle amplification products indicates the presence of the microorganism in the sample.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: April 20, 2021
    Assignee: McMaster University
    Inventors: Yingfu Li, John Brennan, Meng Liu