Patents Assigned to University
  • Nucleic acid catenane with a linking duplex biosensor for detection of a microorganism target
    Patent number: 10982253
    Abstract: The present application is directed to biosensors and methods for detecting a microorganism target in a sample using a mechanically interlocked nucleic acid catanane, wherein an enzyme from the microorganism target or that is activated by a molecule from the microorganism target cleaves a linkage in a first single-stranded nucleic acid ring of the catanane structure, allowing rolling-circle amplification to occur and the presence of rolling-circle amplification products indicates the presence of the microorganism in the sample.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: April 20, 2021
    Assignee: McMaster University
    Inventors: Yingfu Li, John Brennan, Meng Liu
  • Physical random access channel scheme for wireless networks using an analog bloom filter
    Patent number: 10986669
    Abstract: This disclosure describes a novel PRACH scheme based on an Analog Bloom Filter, in which user equipment is allowed to transmit multiple sequences to a base station, instead of only one sequence as is the case with the current LTE. A new decoding algorithm is disclosed, which copes with the unique challenges in the signal generated with ZC sequences, such as peak shifting and multiple peaks. In addition, when CFO can be removed the new scheme allows the UE to piggyback log 2 ? ? 7 bits of information along with the signal. Evaluation shows that the new scheme outperforms the existing PRACH of LTE by more than an order of magnitude in many cases, and therefore is a good candidate as the PRACH for future wireless networks (e.g., 5G).
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: April 20, 2021
    Assignee: The Florida State University Research Foundation, Inc.
    Inventor: Zhenghao Zhang
  • Methods of determining whether anti-PACAP antibodies inhibit PACAP-associated photophobia or light aversion
    Patent number: 10981984
    Abstract: This invention relates to methods of screening for anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof, for potential use in treating or preventing PACAP-associated photophobia or light aversion, and therapeutic compositions containing and methods of using anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: April 20, 2021
    Assignees: H. LUNDBECK A/S, The University of Iowa Research Foundation
    Inventors: Adisa Kuburas, Bianca Mason, Levi P. Sowers, Andrew F. Russo, Maria-Cristina Loomis, Leon F. Garcia-Martinez, Benjamin H. Dutzar, Daniel S. Allison, Katherine Lee Hendricks, Ethan W. Ojala, Pei Fan, Jeffrey T. L. Smith, John A. Latham, Charlie Karasek, Jenny Mulligan, Michelle Scalley-Kim, Erica Stewart, Vanessa Lisbeth Rubin, Jens J. Billgren
  • Levitated charged nanoparticles as a radio frequency transducer
    Patent number: 10983139
    Abstract: A system includes a vacuum chamber to receive a laser beam and a charged nanoparticle. The nanoparticle oscillates at a trapping frequency in a focus of the laser beam. Resonant oscillation of the nanoparticle is driven by a presence of an ambient electric field adjacent to the vacuum chamber. The system also includes a controller to tune the trapping frequency of an oscillating nanoparticle to be in resonance with the ambient electric field causing on-resonant enhancement of the system; a detector to detect positional changes of the oscillating nanoparticle; and a processor to calculate an electromagnetic force of the ambient electric field based on the positional changes of the oscillating nanoparticle.
    Type: Grant
    Filed: March 5, 2020
    Date of Patent: April 20, 2021
    Assignees: Government of the United States, as represented by the Secretary of the Air Force, Utah State University Space Dynamics Laboratory
    Inventors: Sean Krzyzewski, Maxwell D. Gregoire, Brian L. Kasch
  • Intelligent sensing system for indoor air quality analytics
    Patent number: 10982869
    Abstract: Existing indoor air quality monitoring technologies focus on measuring which turn out to be effective in increasing people's awareness of air quality. However, the lack of identification of pollution sources is prone to lead to general and monotonous suggestions. In this disclosure, an indoor air quality analytics system is presented that is able to detect pollution events and identify pollution sources in real-time. The system can also forecast personal exposure to air pollution and provide actionable suggestions to help people improve indoor air quality.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: April 20, 2021
    Assignee: Board of Trustees of Michigan State University
    Inventors: Mi Zhang, Biyi Fang, Taiwoo Park
  • Antimicrobial therapy
    Patent number: 10980848
    Abstract: Methods and compositions comprising hogocidin peptides (SH-lantibiotics), derivatives and variants are provided. Also provided are methods and compositions comprising probiotic compositions utilizing strains of S. hominis and S. epidermidis that produce hogocidin, hogocidin-like peptides, or other inhibitors of skin pathogens. Methods of treatment for microbial skin infections and atopic dermatitis are also provided.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: April 20, 2021
    Assignee: The Regents of the University of California
    Inventors: Teruaki Nakatsuji, Richard L. Gallo
  • Piezoelectric resonance controlled terahertz wave modulators
    Patent number: 10985700
    Abstract: Disclosed are various embodiments of a terahertz wave modulator. The wave modulator can include one or more layers of piezoelectric/ferroelectric single crystal or polycrystalline material. The crystalline material can be configured to resonate when a low-energy external excitation is applied. An incident terahertz waveform can be dynamically controlled when the incident terahertz waveform interacts with the at least one layer of piezoelectric crystalline material while the at least one layer of piezoelectric crystalline material is resonating. The dynamic control of the incident terahertz waveform can be with respect to at least one of a phase shift and an amplitude modulation of the waveform.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: April 20, 2021
    Assignee: Board of Regents, The University of Texas System
    Inventors: Moumita Dutta, Ruyan Guo, Amar Bhalla, Soutik Betal
  • Ultrasensitive magnetic tunneling junction sensor
    Patent number: 10983182
    Abstract: A magnetic tunneling junction sensor includes a free ferromagnetic layer of material, a pinned ferromagnetic layer of material, the free ferromagnetic layer and the pinned ferromagnetic layer separated by a thin insulating layer of material through which electrons can tunnel, an oxidized silicon wafer, the free ferromagnetic layer, thin insulating layer and the pinned ferromagnetic layer deposited on the oxidized silicon wafer, and extrinsic magnetic flux.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: April 20, 2021
    Assignee: Brown University
    Inventors: Gang Xiao, Guanyang He
  • Method and device for inducing motion information between temporal points of sub prediction unit
    Patent number: 10986359
    Abstract: According to the present invention, there is provided A method of encoding a three-dimensional (3D) image, the method comprising: determining a prediction mode for a current block as an inter prediction mode; determining whether a reference block corresponding to the current block in a reference picture has motion information; when the reference block has the motion information, deriving motion information on the current block for each sub prediction block in the current block; and deriving a prediction sample for the current block based on the motion information on the current block.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: April 20, 2021
    Assignee: University-Industry Cooperation Group of Kyung Hee University
    Inventors: Gwang Hoon Park, Min Seong Lee, Young Su Heo, Yoon Jin Lee
  • Reversal of fosfomycin resistance
    Patent number: 10980811
    Abstract: Compounds, pharmaceutical compositions, and methods for reversing fosfomycin resistance are disclosed. Embodiments of the disclosed compounds inhibit fosfomycin-inhibiting enzymes. Some embodiments of the compounds are FosA inhibitors. The disclosed pharmaceutical compositions include (i) fosfomycin or a pharmaceutically acceptable salt thereof and (ii) a compound, or a pharmaceutically acceptable salt thereof, which inhibits a fosfomycin-inhibiting enzyme. A method of inhibiting growth of a fosfomycin-resistant bacterium includes contacting the bacterium with (i) fosfomycin or a pharmaceutically acceptable salt thereof and (ii) an effective amount of a disclosed compound or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: April 20, 2021
    Assignees: University of Pittsburgh—of the Commonwealth System of Higher Education, University of Maryland, Baltimore
    Inventors: Nicolas Paul Sluis-Cremer, Adam Daniel Tomich, Yohei Doi, Eric J. Sundberg, Erik H. Klontz, Steven Fletcher
  • Compositions and methods for suppressing or reducing systemic immune response in a subject
    Patent number: 10980820
    Abstract: The present invention includes a method of suppressing systemic immune response in a subject, the method comprising topically administering a pharmaceutically effective amount of a vitamin D analog to a subject in need thereof. The present invention further includes a method of treating an autoimmune disease in a subject, the method comprising topically administering a pharmaceutically effective amount of a vitamin D analog to a subject in need thereof.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: April 20, 2021
    Assignee: The Trustees of the University of Pennsylvania
    Inventor: Taku Kambayashi
  • Device and method for visual quantification of an amount of target species in a sample solution
    Patent number: 10981165
    Abstract: A device for visual quantification of an amount of target species in a sample solution. The device includes an inlet, a separator, and a trap. The inlet is arranged to receive the sample solution. The separator in fluid communication with the inlet and arranged to separate one or more species from the sample solution. The trap is arranged downstream of the separator, in fluid communication with the separator, and arranged to trap one or more species of the sample solution. The trap is arranged such that the trapped species is visible for determination of the amount of target species in the sample solution.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: April 20, 2021
    Assignee: City University of Hong Kong
    Inventors: Ting-Hsuan Chen, Zichen Zhao
  • MATRIX BOUND VESICLES (MBVS) CONTAINING IL-33 AND THEIR USE
    Publication number: 20210106526
    Abstract: Methods are disclosed for treating a subject with a disorder, such as, but not limited to, a) fibrosis of an organ or tissue; b) solid organ transplant rejection; or c) a cardiac disease that is not myocardial infarction or myocardial ischemia. These methods include selecting a subject having or at risk of having the disorder, and administering to the subject a therapeutically effective amount of isolated nanovesicles derived from an extracellular matrix, wherein the nanovesicles contain interleukin (IL)-33 and comprise lysyl oxidase, and wherein the nanovesicles a) do not express CD63 or CD81, or b) are CD63lo CD81lo. In additional embodiments, methods are disclosed for increasing myoblast differentiation.
    Type: Application
    Filed: May 3, 2019
    Publication date: April 15, 2021
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Stephen Francis Badylak, George S. Hussey, Heth Turnquist, Jenna Lynn Dziki, Quan Liu, Zhongqiang Zhang
  • TRIBLOCK COPOLYMER BASED ANION EXCHANGE MEMBRANES (AEMs) AS SEPARATORS IN ELECTROCHEMICAL DEVICES
    Publication number: 20210111414
    Abstract: The present disclosure is directed to triblock copolymer based anion exchange membranes (AEMs) and methods for making same. The membranes are useful as separators in electrochemical devices, such as fuel cells, electrolyzers, water desalination systems, and redox flow batteries.
    Type: Application
    Filed: December 7, 2020
    Publication date: April 15, 2021
    Applicant: Washington University
    Inventors: Zhongyang Wang, Javier Parrondo, Vijay K. Ramani
  • METHOD FOR DETECTING COPPER(II) IONS USING A HYDRAZONE-BASED COLORIMETRIC SENSOR
    Publication number: 20210109027
    Abstract: Cu(II) detection in the presence of main group heavy metal ions and d-, f- and g-element interferents relies on a colorimetric chelating complex between 3-hydroxy-5-nitrobenzaldehyde-4-hydroxybenzoylhydrazone (3-HNHBH) and Cu(II). Derivatives and entrapped forms of the probe were aligned with the methods of analysis, featuring spectrophotometric, reflectometric, lateral flow, microfluidic, lab-on-paper, positional array, dynamic array, flow cytometry and tandem stage devices. A remotely operating software capable of DFT calculations predicted the observed detection limit of 0.34 ?g L?1 (<5 nM) as well as high selectivity towards copper ions in the presence of competing Zn+2 and Ni+2. The probe was readily regenerated against metal complexation by using a 0.5 M HCl solution, indicating its feasibility to be a re-usable sensor for the convenient detection of copper ions in water-organic media.
    Type: Application
    Filed: October 9, 2019
    Publication date: April 15, 2021
    Applicant: King Fahd University of Petroleum and Minerals
    Inventors: Chanbasha BASHEER, Abdulaziz A. AL-SAADI, Ismail ABDULAZEEZ
  • DOMINO FULL ADDER BASED ON DELAYED GATING POSITIVE FEEDBACK
    Publication number: 20210109710
    Abstract: A domino full adder based on delayed gating positive feedback comprises a first PMOS transistor, a second PMOS transistor, a third PMOS transistor, a fourth PMOS transistor, a fifth PMOS transistor, a sixth PMOS transistor, a seventh PMOS transistor, an eighth PMOS transistor, a ninth PMOS transistor, a first NMOS transistor, a second NMOS transistor, a third NMOS transistor, a fourth NMOS transistor, a fifth NMOS transistor, a sixth NMOS transistor, a seventh NMOS transistor, an eighth NMOS transistor, a ninth NMOS transistor, a tenth NMOS transistor, an eleventh NMOS transistor, a first inverter, a second inverter, a third inverter and a fourth inverter.
    Type: Application
    Filed: October 13, 2020
    Publication date: April 15, 2021
    Applicant: Ningbo University
    Inventors: Pengjun WANG, Xiaotian ZHANG, Huihong ZHANG, Yuejun ZHANG, Haizhen Yu
  • DESALINATION SYSTEMS, APPARATUS, AND RELATED METHODS FOR USE WITH SALINE FLUIDS
    Publication number: 20210107807
    Abstract: Desalination systems, apparatus, and related methods for use with saline fluids are disclosed. A disclosed desalination system includes an HDH system including a humidifier and a dehumidifier that, together, are configured to process a first saline fluid to produce freshwater in the dehumidifier. The desalination system also includes an AD system operatively coupled to the HDH system. The AD system includes a first bed, a second bed, an evaporator, and a condenser that, together, are configured to process a second saline fluid to produce freshwater in the condenser. The condenser is configured to transfer heat exhausted by the first or second bed from a vapor, obtained from the second saline fluid, to air circulating through the humidifier and the dehumidifier to drive the HDH system. The evaporator is configured to provide a cooling effect.
    Type: Application
    Filed: October 11, 2019
    Publication date: April 15, 2021
    Applicant: King Fahd University of Petroleum and Minerals
    Inventors: Naef A.A. QASEM, Syed M. ZUBAIR
  • BIARYL SULFONAMIDE DERIVATIVE HAVING FILOVIRUS CELL ENTRY INHIBITION ACTIVITY
    Publication number: 20210107871
    Abstract: The objective of the present invention is to provide a novel compound inhibiting the entry of a filovirus into a cell, a medical composition, an anti-filovirus agent, or a filovirus entry inhibitor containing the compound, as well as a method for inhibiting a filovirus cell entry process in vitro, a method for treating a filovirus infectious disease, and the like. The objective has been achieved by providing: the compound represented by formula (I) or a hydrate thereof; or a pharmaceutically acceptable salt of the compound or a hydrate thereof.
    Type: Application
    Filed: March 30, 2018
    Publication date: April 15, 2021
    Applicant: National University Corporation Hokkaido University
    Inventors: Ayato Takada, Masahiro Sakaitani, Wakako Furuyama
  • ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
    Publication number: 20210111354
    Abstract: Provided is a compound of Formula Ir(LA)(LB)(LC), wherein LA is a ligand of LB is a ligand of and LC is a ligand of wherein a structure of is fused to the ligand LB of Formula II through two adjacent C of X1-X4.
    Type: Application
    Filed: September 29, 2020
    Publication date: April 15, 2021
    Applicant: Universal Display Corporation
    Inventors: Jui-Yi TSAI, Alexey Borisovich DYATKIN, Zhiqiang JI, Pierre-Luc T. BOUDREAULT
  • Strawberry plant named ‘UCD Valiant’
    Patent number: PP32984
    Abstract: ‘UCD Valiant’ is a day-neutral cultivar of a strawberry plant that provides high yields and produces large, firm fruit. The variety has performed particularly well in low-input and organic production systems.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: April 20, 2021
    Assignee: The Regents of the University of California
    Inventors: Steven J. Knapp, Glenn S. Cole, Douglas V. Shaw, Kirk D. Larson