Abstract: Systems and methods for generating scheduling options in consideration of space and resource constraints in accordance with embodiments of the invention are disclosed. One embodiment of the invention includes a scheduling application that configures the processor to generate a project schedule from a TODO list comprising a plurality of construction operations, where the construction operations comprise at least one specific space requirements within a construction site, resource requirements, and a duration time.

Abstract: The present disclosure is directed towards a disposable microfluidic cartridge configured for use in a system for the small scale production of nanoparticles used in scientific research or therapeutic applications. The system can be used to produce a wide variety of nanoparticles, including but not limited to lipid and polymer nanoparticles, carrying a variety of payloads. The system provides for a simple workflow which in certain embodiments can be used to produce a sterile product.

Abstract: Electrowetting-actuated optical shutters based on total internal reflection or beam steering. An electrowetting cell contains a conducting liquid and a non-conducting liquid configured to form a liquid-liquid interface extending to the inner walls of the cell. A beam of light is directed to the liquid-liquid interface at an angle near the total internal reflection angle of the interface. Voltage changes the shape of the liquid-liquid interface, without separating it from the inner walls of the cell. Thus, when depending on the voltage applied, the beam is either transmitted in part or substantially totally internal reflected.

Abstract: Disclosed herein is a 3D-printed, biocompatible macroporous device that houses stem cell derived ?-cell (SC-? cell) clusters within a degradable fibrin gel. Cluster sizes are used that avoid severe hypoxia within 3D-printed devices and a microwell-based technique is used for resizing clusters within this range. 3D-printed devices may function for at least 12 weeks, are retrievable, and maintain structural integrity.

Abstract: Disclosed are devices, systems, apparatus, methods, products, media and other implementations, including a method that includes triggering a beacon circuit combined with a hardware-based protection module, included within a hardware device, the hardware-based protection module configured to provide protection against malicious implementations within the hardware device, with the beacon circuit being configured to provide a beacon output when triggered. The method further includes determining based on the beacon output provided by the triggered beacon circuit whether the hardware device includes at least one malicious implementation.

Abstract: A system includes a first energy storage device, a second energy storage device coupled to the first energy storage device and charged via a charging current from the first energy storage device, a power controller having a processor, a memory coupled to the processor and on which charging current instructions are stored, and a converter coupled to the processor and directed via switch control signals from the processor, and an output terminal via which power is provided to a load of the system. The converter is disposed between the first energy storage device and the output terminal. The converter is disposed between the first and second energy storage devices and configured to control a level of the charging current in accordance with the switch control signals. The charging current instructions are executed by the processor to cause the processor to generate the switch control signals such that the level of the charging current is regulated.

Abstract: Methods of improving mammalian carbohydrate metabolism and treating, preventing, or halting the progression of type 2 diabetes mellitus involve the consumption of a nutritional composition containing fruit or vegetable pomace. The pomace is produced from native plant tissue and contains a mixture of soluble and insoluble fiber. Periodic consumption of the composition normalizes blood glucose concentration and controls body weight.

Abstract: A method for detecting distributed concurrency errors in a distributed cloud computing system includes tracing operations that access objects in functions involving inter-process messaging, applying a set of happens-before rules to the traced operations. Analyzing the traced operations to identify concurrent operations that access a common object to generate a list of potential distributed concurrency errors (DCbugs). Pruning the list of DCbugs to remove DCbugs having only local effect and that do not generate run-time errors.

Abstract: Provided herein are compositions, for example: oral rehydration compositions, beverages, food items, methods and uses, which utilise resistant starch to prevent or treat dehydration, including dehydration which is caused by diarrhoea. Beverages, food items and oral rehydration solutions including a resistant starch, which are suitable for aiding in the maintenance and restoration of hydration levels in individuals undertaking physical activities, including sports, are also disclosed.

Abstract: The present disclosure relates to a method of analysis by an optical marker, including: irradiating a broadband light source onto a spherical dielectric material; measuring an interference spectrum of reflected light from the spherical dielectric material; and analyzing the reflected light using thin-film interference theory.

Abstract: Biocompatible hydrogel compositions according to aspects of the present invention are provided wherein the biocompatible hydrogel composition is or includes a physical hydrogel, a chemical hydrogel or both a physical hydrogel and a chemical hydrogel, along with biocompatible hydrogel compositions encapsulating a therapeutic agent and methods of use thereof.

Abstract: Implantable passive engineered mechanisms and a method for implanting such devices in a subject are described. The implantable passive engineered mechanism may be made of or comprise a biocompatible material and is appropriately sized for implantation in a subject. Exemplary implantable passive engineered mechanisms may be selected from a strut, a pulley, a lever, a compliant mechanism, a scissor lift, a tendon network, springs, planetary gears, rigid or soft hydraulics, a linkage system, a cam/clutch system, or combinations thereof. In some embodiments the system comprises plural inserts, such as pulleys, levers, and/or tendon networks. Plural inserts may be arranged hierarchically to distribute force differentially from an input to one or more outputs.

Abstract: Various samples are generated on a substrate. The samples each includes or consists of one or more analytes. In some instances, the samples are generated through the use of gels or through vapor deposition techniques. The samples are used in an instrument for screening large numbers of analytes by locating the samples between a working electrode and a counter electrode assembly. The instrument also includes one or more light sources for illuminating each of the samples. The instrument is configured to measure the photocurrent formed through a sample as a result of the illumination of the sample.

Abstract: To obtain a novel therapeutic drug for a malignant tumor or fibrosis. Used is a compound represented by formula (1), a salt thereof, or a solvate thereof. Also used is a therapeutic drug for a malignant tumor or a therapeutic drug for fibrosis, comprising a compound represented by formula (1), a salt thereof, or a solvate thereof.

Abstract: The present application is directed to electric double layer capacitance (EDLC) devices. In one aspect, the present application is directed to an electrode comprising an activated carbon cryogel having a tunable pore structure wherein: the surface area is at least 1500 m2/g as determined by nitrogen sorption at 77K and BET analysis; and the pore structure comprises a pore volume ranging from about 0.01 cc/g to about 0.25 cc/g for pores having a pore diameter of 0.6 to 1.0 nm. In another aspect, the present application is directed to an Electric Double Layer Capacitor (EDLC) device comprising an activated cryogel.

Abstract: New 1,3-dipenyl pyrazole derived azomethines and N-aryl amines have been synthesized. These anti-MRSA agents combat MRSA and other infections. These azomethine and N-arylamine derivatives of benzoic acid provide combat MRSA and other infections.

Abstract: Surrogates for roadside objects, such as concrete dividers, can be used for vehicle testing. A surrogate for a concrete divider can have substantially the same size and/or shape as the concrete divider that the surrogate is mimicking. The surrogate can be configured to exhibit substantially the same characteristics as their actual counterpart concrete divider when sensed by one or more vehicle sensors (e.g., cameras, radar sensors, and/or LIDAR sensors). Such surrogates can be used to test autonomous vehicles, one or more vehicle sensors, a vehicle sensor system, and/or one or more vehicle system (e.g., a road departure mitigation system). The surrogates can be configured to withstand being crashed into by a test vehicle without being damaged and without damaging the test vehicle.

Abstract: Provided are methods of removing perchlorate from water. The methods include contacting water suspected of containing perchlorate with a cationic material. The cationic material includes one or more cationic metal atoms connected by an atom or molecule into an extended structure, and a charge balancing anion. The contacting removes perchlorate (e.g., selectively), if present, from the water. Water treatment vessels, systems and facilities that find use in practicing the methods of the present disclosure are also provided.

Abstract: Provided herein are methods and devices for the detection of analytes. The methods employ particles formed from a first metal conjugated to analytes. The analyte conjugated to the particle formed from the first metal can be accumulated at a working electrode. The first metal can be galvanically exchanged with ions of a second metal to form a layer of the first metal at the working electrode. The first metal can then be electrochemically detected and/or quantified. Using this method, analytes can be detected at low concentrations a few femtomolar via anodic stripping voltammetry, with no washing steps or electrode modifications.

Abstract: Co-clustering based on generalized conceptual relationships can automatically detect story forms incorporating archetypes/targets and actions. Co-clustering can help in identifying similarities that exist in low-dimensional sub-spaces of sparse data such as textual paragraphs. Through co-clustering, the clusters themselves and their characteristic features are identifiable which can be useful in describing and summarizing their contents. The residual error of factorization with concept-based features is significantly lower than the error with prior keyword-based features. Qualitative evaluations also suggest that concept-based features yield more coherent, distinctive and interesting story forms compared to those produced by using prior keyword-based features.