Abstract: An improvement of coercive force of Nd—Fe—B base sintered magnet can be realized while suppressing a decrease in remanent magnetic flux density to the minimum using a method for modifying grain boundary which comprises heat-treating an Nd—Fe—B base magnet with a specific alloy disposed on its surface, the alloy having the following Formula 1: RxAyBz??(1) wherein R represents at least one rare earth element including Sc and Y, A represents Ca or Li, B represents an unavoidable impurity, and 2?x?99, 1?y<x, and 0?z<y.
Type:
Grant
Filed:
October 12, 2016
Date of Patent:
March 17, 2020
Assignees:
Nissan Motor Co., Ltd., Osaka University
Abstract: Metal halide optical materials (e.g., scintillator materials or persistent phosphors) are described. More particularly, the optical materials include codoped perovskite-type halides, wherein the codoping ion is present at a molar ratio of 5000 parts per million (ppm) or less with respect to all cations. For example, the optical material can be a codoped trihalide having the formula ABX3 where A is one or more alkali metal, B is one or more alkali earth metal, and X is one or more halide that is doped with up to about 10 atomic percent of a dopant ion and codoped with up to about 5000 ppm of one or more isovalent or aliovalent codopant ion, such as a tetravalent ion (e.g., Zr4+), a trivalent ion (e.g., Sc3+, Y3+, Gd3+, or La3+ ion) or a divalent ion (e.g., Mg2+). The codoped material can have modified afterglow compared to a noncodoped material.
Type:
Grant
Filed:
May 3, 2018
Date of Patent:
March 17, 2020
Assignee:
University of Tennessee Research Foundation
Inventors:
Yuntao Wu, Mariya Zhuravleva, Luis Stand, Charles L. Melcher
Abstract: A radial-gap type superconducting synchronous machine 1 is prepared which includes a rotor 20 having, on its peripheral side, a convex magnetic pole 21 which includes, at its distal end part, bulk superconductors 30. When viewed in the direction of the rotational axis C1 of the rotor 20, the magnetic pole center side of the bulk superconductors 30 is disposed nearer to a stator 10 than the magnetic pole end side of the bulk superconductors 30. A ferromagnet 28 is disposed on the rotational axis C1 side of the bulk superconductors 30. A magnetizing apparatus 100 is disposed outside the bulk superconductors 30 in the radial direction of the rotor 20. Magnetization of the bulk superconductors 30 is performed by directing magnetic flux lines from the magnetizing apparatus 100 toward the bulk superconductors 30.
Type:
Grant
Filed:
March 25, 2015
Date of Patent:
March 17, 2020
Assignee:
National University Corporation Tokyo University of Marine Science and Technology
Abstract: Provided herein are kits, compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to recurrent gene fusions (e.g., recurrent translocations involving TYK2) as diagnostic markers and clinical targets for cutaneous CD30-positive lymphoproliferative disorders (e.g., lymphomatoid papulosis; primary cutaneous anaplastic large cell lymphoma).
Type:
Grant
Filed:
January 29, 2016
Date of Patent:
March 17, 2020
Assignee:
The Regents of the University of Michigan
Inventors:
Kojo Elenitoba-Johnson, Mark J. Kiel, Delphine Rolland, Bryan L. Betz, Nathanael G. Bailey, Thirunavukkarasu Velusamy, Megan Lim
Abstract: Electropolymerized polymer or copolymer films on a conducting substrate (e.g., graphene) and methods of making such films. The films may be part of multilayer structures. The films can be formed by anodic or cathodic electropolymerization of monomers. The films and structures (e.g., multilayer structures) can be used in devices such as, for example, electrochromic devices, electrical-energy storage devices, photo-voltaic devices, field-effect transistor devices, electrical devices, electronic devices, energy-generation devices, and microfluidic devices.
Type:
Grant
Filed:
April 3, 2015
Date of Patent:
March 17, 2020
Assignee:
Cornell University
Inventors:
Sean Conte, Gabriel G. Rodriguez-Calero, Cen Tan, Kenneth Hernandez-Burgos, Hector D. Abruna, Nicole Ritzert, Daniel C. Ralph, Wan Li
Abstract: A three-dimensional electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a flexible deposited fiber network of varying density including a first and second set of set of electrospun fibers. The second set of electrospun fibers is coupled to the first. A first portion of the flexible deposited fiber network includes a higher density of fibers than a second portion of the flexible deposited fiber network, and the tensile strength of first portion is higher than that of the second portion. The scaffold is sufficiently flexible to facilitate application of scaffold to uneven surfaces of the tissue substrate, and enables movement of the scaffold by the tissue substrate. The first and second set of fibers are configured to degrade within three months after application, and each fiber of the deposited fiber network has a diameter of 1-1000 nanometers.
Type:
Grant
Filed:
August 14, 2019
Date of Patent:
March 17, 2020
Assignee:
Washington University
Inventors:
Matthew R. MacEwan, Jingwei Xie, Zack Ray, Younan Xia
Abstract: Provided herein are methods for identifying high potency genomic insulator elements that can be used in a vector composition e.g., that are useful for preventing unwanted expression of neighboring genes, such as proto-oncogenes, when administered to a subject in need thereof. Also provided herein are methods for treating disease and methods for administering a nucleic acid to a subject using such vectors.
Type:
Grant
Filed:
March 13, 2015
Date of Patent:
March 17, 2020
Assignee:
University of Washington
Inventors:
George Stamatoyannopoulos, John Stamatoyannopoulos
Abstract: A system and method for conditioning a tissue are provided. The system includes a substrate, a plurality of microwells formed in the substrate, and a microsphere associated with each of the plurality of microwells. The system also includes a pair of flexible pillars within each of the plurality of microwells. Each flexible pillar includes a first end bonded to a respective microwell and at least one flexible pillar has a second end bonded to the microsphere. The flexible pillars are configured to deflect when exposed to a magnetic field to controllably stretch microtissue spanning the flexible pillars.
Type:
Grant
Filed:
November 20, 2015
Date of Patent:
March 17, 2020
Assignee:
The Johns Hopkins University
Inventors:
Daniel H. Reich, Fan Xu, Ruogang Zhao, Alan S. Liu, Tristin Metz, Yu Shi
Abstract: A retrospective reconstruction method uses cardiac self-gating for patients with severe arrhythmias. Self-gated myocardial systolic and diastolic motion is determined from low-spatial and high-temporal resolution images and then the MRI-dataset is retrospectively reconstructed to obtain high quality images. The method uses undersampled image reconstruction to obtain the low-spatial and high-temporal resolution images, including those of different beat morphologies. Processing of these images is utilized to generate a cardiac phase signal. This signal allows for arrhythmia detection and cardiac phase sorting. The cardiac phase signal allows for detection of end-systolic and diastolic events which allows for improved sampling efficiency. In the case of frequent and severe arrhythmia, the method utilizes data from the normal and interrupted beats to improve sampling and image quality.
Type:
Grant
Filed:
April 24, 2015
Date of Patent:
March 17, 2020
Assignee:
The Trustees of the University of Pennsylvania
Inventors:
Francisco Contijoch, Walter R. T. Witschey, Robert C. Gorman, Yuchi Han, Joseph H. Gorman, III
Abstract: Described herein are mutant cyanobacterial cell populations that have a smaller mean cell length than wild type cyanobacterial cell populations of the same species.
Type:
Grant
Filed:
August 22, 2017
Date of Patent:
March 17, 2020
Assignee:
Board of Trustees of Michigan State University
Inventors:
Daniel Christopher Ducat, Katherine Osteryoung, Joshua Scott MacCready
Abstract: A process for producing a munitions structure includes combining two or more transition metals including one or more of Zr, Hf, Ti, Ta, or Nb, and one or more other elements as alloying additions. The process further includes heating and fusing together the two or more transition metals and the one or more alloying additions to form a homogenous molten alloy. The homogenous molten alloy is cooled in a metallic mold to form a solid object with a desired shape for the munitions structure.
Abstract: The present invention relates to novel strains of avian reovirus that were isolated from clinical cases of viral arthritis/tenosynovitis in chickens in the southeast United States. The invention is directed to these novel group 1 and group 2 avian reoviruses, diagnostic assays using antibodies and/or nucleotide- or amino acid-specific components of such viruses, such as the S1 gene encoding the sigma C protein, and to vaccines that protect chickens from disease caused by such viruses.
Type:
Grant
Filed:
April 23, 2018
Date of Patent:
March 17, 2020
Assignee:
University of Georgia Research Foundations, Inc.
Abstract: Disclosed is a limonene-sulfur polysulfide and methods for preparing the same. The polysulfide prepared according to these methods is flexible, moldable and otherwise capable of being formed in any manner consistent with a thermoplastic polymer. The limonene-sulfur polysulfide has been demonstrated to sequester inorganic palladium and inorganic mercury dissolved in water.
Type:
Grant
Filed:
October 13, 2015
Date of Patent:
March 17, 2020
Assignee:
The University of Tulsa
Inventors:
Justin M. Chalker, Sr., Michael P. Crockett, Austin M. Evans, Max Worthington
Abstract: A magnetic current dipole feeding structure for patch and dielectric resonator antennas is disclosed in which a wire coil helix is placed above the ground plane and below the patch or top of the dielectric resonator block, the coil having half wound in a right-hand orientation and another half in a left-hand orientation, meeting at a common point in the middle. One end of the double torsion coil can be excited with radio frequency (RF) signals, and the other can be grounded on the ground plane. Some embodiments have the other end fed by an equal signal. These double torsion coils can be used in pairs to provide differential feeding to the patch or dielectric resonator, and pairs placed orthogonally to a first pair can be used for another polarization.
Abstract: Provided are novel biocompatible copolymers, compositions comprising the copolymers, and methods of using the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers.
Type:
Grant
Filed:
April 14, 2015
Date of Patent:
March 17, 2020
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education
Inventors:
Hongbin Jiang, William R. Wagner, Tomo Yoshizumi, Yang Zhu
Abstract: A method for acquiring magnetic resonance imaging data from a subject. The method includes performing a series of radio frequency pulses formed of individual RF pulses applied with a constant time interval between each of the individual RF pulses to form a consistent magnetic field about at least of a region of interest in the subject, where the RF pulse has a flip angle of less than 30 degrees. The method also includes performing phase encoding gradients to achieve spatial encoding and performing an imaging acquisition process over an acquisition window to acquire imaging data. The method further includes performing phase encoding rephasing gradients and repeating the preceding steps such that a time between a center of the acquisition window and a center of a first RF pulse in a first RF pulse in a repetition of the RF pulses is equal to the constant pulse interval.
Type:
Grant
Filed:
October 13, 2017
Date of Patent:
March 17, 2020
Assignee:
Regents of the University of Minnesota
Inventors:
Naoharu Kobayashi, Djaudat Idiyatullin, Michael Garwood
Abstract: A logic gate and a cascaded logic family is described that uses the unique ambipolar behavior, e.g., of carbon nanotubes. A complementary VT-drop ambipolar carbon nanotube logic can provide a decrease in device count compared to previous ambipolar carbon nanotube field effect transistor logic structures, enabling power and/or speed improvements.
Type:
Grant
Filed:
May 10, 2017
Date of Patent:
March 17, 2020
Assignee:
Northwestern University
Inventors:
Joseph S. Friedman, Michael L. Geier, Mark C. Hersam, Alan V. Sahakian