Abstract: A contactless system for assessing tissue viability and other hemodynamic parameters includes one or more light sources configured to emit lights at a predetermined wavelength sensitive to hemoglobin concentration associated with spontaneous hemodynamic oscillations at tissue in a predetermined area of a human subject. One or more polarizers are each coupled to one or more of the one or more light sources and are configured to polarize the light to a polarized state such that the polarized light in the polarized state diffuses into the tissue in the predetermined area at a predetermined depth and the polarized light is maintained in the polarized state at the predetermined depth. One or more detectors each including a detector polarizer coupled thereto are configured to discriminate the light maintained in the polarized state and at the predetermined depth and are configured to generate a plurality of frames of the tissue in the predetermined area at the predetermined depth.

Abstract: A simple one pot sol-gel method for the synthesis of bi-metal nanostructures is based on non-noble metals (Fe, Co and Sn) and titanium. The method involves the synthesis of mixed metal nanoscale composites using low cost precursors which allow for the synthesis of desired nanocomposite materials with self-scarifying titanium or silica supports. The procedure does not require any surfactant or any need for pH controlled step. Applicants' method involves the in-situ generation of precursors and their simultaneous entrapment in a gel. This simple one pot synthesis allows for the synthesis of homogenous size, shape and distribution of targeted nanostructures. Further, this method can be applied for the preparation of various nanocomposite materials using different choices of metals and self-scarifying supports. Applicants also show that Pd, the noble metal based nanocomposite is feasible.

Abstract: The present invention provides methods for diagnosing a patient with emphysema, COPD of lung injury caused by tobacco use by detecting the levels of EMAP II in a sample. Disclosed herein are the hypervariable regions for a rat monoclonal antibody that binds to a form of EMAP II. This disclosure also includes a polypeptide sequence included in EMAP II that is the target for the binding of the antibody to its target protein. This epitope serves as the basis for a humanized antibody that can be used to treat patients that suffer from pathologies that exhibit elevated levels of EMAP II expression.

Abstract: Disclosed herein are anti-Galectin-9 antibodies and methods of using such for inhibiting a signaling pathway mediated by Galectin-9 or eliminating pathologic cells expressing Galectin-9. Such anti-Galectin-9 antibodies may also be used to diagnose and/or to treat diseases associated with Galectin-9, such as autoimmune diseases and solid tumors.

Abstract: This invention is directed to a method of diagnosing bladder cancer in dogs.

Abstract: Several methods for prediction and detection of neurological events are proposed based on spatiotemporal patterns in recorded neural signals. The methods are illustrated with examples from neural data recorded from human and non-human primates.

Abstract: Techniques are described for data transfer in spin-based systems where digital bit values are represented by magnetization states of magnetoresistive devices rather than voltages or currents. For data transmission, a spin-based signal is converted to an optical signal and transmitted via an optical transport. For data reception, the optical signal is received via the optical transport and converted back to a spin-based signal. Such data transfer may not require an intervening conversion of the spin-based signal to charge-based signal that relies on voltages or currents to represent digital bit values. In addition, techniques are described to use magnetoresistive devices to control the amount of current or voltage that is delivered, where the magnetization state of the magnetoresistive device is set by an optical signal.

Abstract: A system and method of determining a data collection routing protocol include the steps of perceiving a broadcast beacon message from an i-th sensor node located at an i-th sensor level by one or MOW sensor nodes at one or more other sensor levels of a divided WSN, wherein the i-th sensor level does not include a first sensor level of a sink sensor node; resetting the respective sensor level of the one or more sensor nodes to an (i+1)th sensor level; attempting to connect the i-th sensor node at the i-th sensor level to another sensor node located at an (i?1)th sensor level; and connecting the i-th sensor node to a parent sensor node at the i-th sensor level when certain conditions are met. These conditions are determined and analyzed locally at each sensor node.

Abstract: Provided herein are compounds having the general formula compositions, and methods useful for treating cancer and neurodegeneration. The compounds comprise a mitochondria-targeting moiety linked to ?-lapachone or a ?-lapachone derivative.

Abstract: The invention relates to compositions and methods for reducing excessive vascular development and treat related disorders. In one aspect, the invention provides methods for treating, reducing or inhibiting vascular development in a subject in need thereof. The methods of the invention comprises administering to the subject an effective amount of a HK2 depleting agent that decreases the level of expression and/or activity of HK2. In some embodiments, the level of expression and/or activity of fibroblast growth factor receptor (FGFR), FGF ligand and/or FGF signaling is/are decreased. The invention also includes methods for diagnosing excessive vascular development and for measuring the efficacy of a treatment for an excessive vascular development in a subject in need thereof. The invention further includes a pharmaceutical composition for treating or reducing angiogenesis or lymphangiogenesis, comprising a HK2 depleting agent and a pharmaceutical acceptable carrier.

Abstract: A gas delivery device includes a nitric oxide generating system. The system has a medium including a source of nitrite ions. A working electrode is in contact with the medium. A Cu(II)-ligand complex is in contact with the working electrode. A reference/counter electrode is, or a reference electrode and a counter electrode are in contact with the medium and separated from the working electrode. An inlet conduit is to deliver nitrogen gas to the medium, and an outlet conduit is to transport a stream of nitrogen gas and nitric oxide from the medium. An inspiratory gas conduit is operatively connected to the outlet conduit to introduce an oxygen-containing gas and form an output gas stream of the gas delivery device.

Abstract: The compositions and methods described herein are topically applied to the skin with negligible or no skin irritation and can direct or prevent transport through the skin. The compositions contain neat ionic liquids, optionally in combination with a drug to be delivered. In a preferred embodiment, the compositions increase transdermal transport of the drug to be delivered. In some embodiments, the compositions disrupt bacterial biofilms. This is particularly beneficial in the treatment of antibiotic resistant skin infections. In other embodiments, the compositions direct delivery within the skin. In still other embodiments, the compositions prevent transfer of substances through the stratum corneum. The disclosed compositions and methods can be tuned and modified such that they can be used to treat or prevent a variety of different diseases and disorders.

Abstract: The present disclosure relates to a 5th generation (5G) or pre-5G communication system for supporting a high data transmission rate beyond a 4th generation communication system such as long term evolution (LTE). An operation method of a base station in a wireless communication system according to an embodiment of the present invention comprises the steps of: receiving at least one random access preamble from at least one terminal; and transmitting at least one message including a plurality of random access responses corresponding to the at least one random access preamble.

Abstract: The invention provides a coating which exhibits fast oleophobic-hydrophilic switching behaviour with, for example, equilibration of high oil contact angle (hexadecane=80°) and low water contact angle (<10°) values which occur within 10 s of droplet impact. These optically transparent surfaces display excellent anti-fogging and self-cleaning properties. The magnitude of oleophobic-hydrophilic switching can be further enhanced by the incorporation of surface roughness and in one embodiment the coating is applied to a surface in the form of a mesh in order to form an effective filter.

Abstract: A method for measurement of an information-security-controlling status in accordance with the present disclosure includes receiving actual inspection data obtained by actually inspecting whether each domain complies with each security-controlling item, computing security-controlling status measurement scores for each domain on the basis of a significance grade of each control item, the degree of compliance with a corresponding control item, and a weighting set by a measurement manager, computing a final security-controlling status measurement score for a parent organization to which each domain belongs on the basis of an average of the security-controlling status measurement scores for each domain, and outputting the computed security-controlling status measurement scores and final security-controlling status measurement score.

Abstract: A spectrometer device for analysis of aerosol particles, dusts, and other microparticles and/or nanoparticles includes an electrospray ionization source supplying a particle stream to an aerodynamic lens that focuses and collimates a beam of particles. An electrostatic trap accepts the beam of particles and traps a single trapped particle at a time in the electrostatic trap to oscillate with a measurable amplitude and frequency. A sensor senses the amplitude and frequency, and a processor determines a calculated mass to charge ratio from the amplitude and frequency of oscillation of the trapped particle in real time. A method creates a focused stream of micro or nanoparticles, traps a single particle at a time in an electrostatic trap. The amplitude and frequency of the oscillation of the trapped particle is sensed. The mass to charge ratio is determined from the amplitude and frequency of oscillation. Particles can be accelerated into a target.

Abstract: An object of the present invention is to provide a method for producing conductive mayenite, with which a reaction is completed in a short time, an operation can be simplified, the reaction is easily controlled, and the cost of energy can be reduced. The present invention is a method for producing conductive mayenite, characterized by mixing a mayenite type compound with a carbon component, placing the resulting mixture in an airtight container, and irradiating the mixture with a microwave in an inert gas atmosphere or in a vacuum atmosphere to heat the mixture.

Abstract: The present disclosure discloses an imaging system, method, and apparatus for identifying information of a hidden object. A light source generates a first beam of narrow-band light and a second beam of narrow-band light that has temporal fluctuations correlated with the first beam. The first beam is directed towards a first scattering surface and the second beam is directed towards a second scattering surface. The first scattering surface scatters the first beam to a scattered light that illuminates a hidden object, the hidden object reflects at least a portion of the scattered light towards the second scattering surface, the reflected light interferes with the second beam and produces an interference pattern on the second scattering surface. An image sensor detects irradiance of the interference pattern on the second scattering surface.

Abstract: This document relates to materials and methods for treating cancer (e.g., prostate cancer). For example, methods for using one or more androgen receptor variant (AR-V) inhibitors (e.g., morpholinos) to treat a mammal having prostate cancer (e.g., castration-resistant prostate cancer) are provided.

Abstract: In some embodiments, a beam scanning antenna includes a lens having a focal surface and a microfluidic beam scanning focal plane array associated with the focal surface, the array including: an elongated microfluidic channel that contains an electrically conductive antenna element suspended within a dielectric fluid that is provided within the channel, the channel including multiple microfluidic chambers that are positioned at discrete locations along a length of the channel, wherein the antenna element can be selectively positioned within selected chambers, and means for moving the position of the antenna element along the channel to change a direction along which electromagnetic waves are transmitted or received.