Abstract: Disclosed are methods of fiber spinning and polymer fibers that utilize multifunctional thiol and enes compounds. Also, the subject matter disclosed herein relates to uses of polymer fibers and articles prepared from such fibers.

Abstract: Sensing voltage based on a supplied to magneto-resistive random access memory (MRAM) bit cells in an MRAM for tracking write operations. Sensing voltage based on supply voltage applied to an MRAM bit cell in a write operation can be used to detect completion of magnetic tunnel junction (MTJ) switching in an MRAM bit cell to terminate the write operation to reduce power and write times. In exemplary aspects provided herein, reference and write operation voltages sensed from the MRAM bit cell in response to the write operation are compared to each other to detect completion of MTJ switching of voltage based on the supply voltage applied to the MRAM bit cell regardless of whether the write operation is logic ‘0’ or logic ‘1’ write operation. This provides a higher sensing margin, because the change in MTJ resistance after MTJ switching completion is larger at the supply voltage rail.

Abstract: Described herein are recognition modules that bind specifically to a template nucleic acid and which ligate together in a reducing environment to produce a gamma peptide nucleic acid (?PNA) oligomer. Also provided are methods of synthesizing a ?PNA oligomer on a template using the recognition modules.

Abstract: Polymer/copper combinations that can selectively target and kill cancer cells are described. Materials can include the reaction product of a biocompatible hydrophilic polymer and pyridine-2-thiol containing monomer. The copolymer reaction product can include pyridine-2-thiol side groups pendant to the backbone via a disulfide linkage. The hydrophilic component can form the polymer backbone and/or can form hydrophilic pendant groups off of the backbone. Copper ions can be associated with the copolymer.

Abstract: A compact magnetic-based battery device that offers energy, a large number of cycles, a long storage time, and a short charging time is provided. The rechargeable battery device can include a first magnetic layer, a second magnetic layer, a dielectric layer disposed between the first magnetic layer and the second magnetic layer, and a plurality of high anisotropic magnetic nanoparticles embedded into the dielectric layer.

Abstract: The invention includes methods and materials for forming and manipulating aromatic-based polymers and copolymers using biomass compounds as starting materials. Embodiments of the invention can be used in processes designed to replace those used in the petro-chemical industry. Typical embodiments of the invention include methods and materials for forming and/or modifying compounds including dicarboxylic acid ester dimers, benzoxazines and dicarboxylic acid ether dimers. Embodiments of the invention further provide methods and materials for utilizing these compounds to form commercially desirable polymers having structures and physical properties akin to those found in polymers formed from petroleum products.

Abstract: Ritanserin is shown to be an inhibitor of diacylglycerol kinase alpha (DGK?) and to be cytotoxic to glioblastoma and melanoma cells. Ritanserin treatment also provides chemo- and radiosensitization in cancer cells, prolonged survival in mouse models of glioblastoma, decreased melanoma tumor burden in mice, and shows synergistic cytotoxic effects with temozolomide and chloroquine, both singly and in combination. DGK? inhibition with ritanserin shows particular toxicity to the treatment-resistant mesenchymal subtype in glioblastoma and other cancers.

Abstract: The disclosed embodiments relate to a system that implements a photonic neuron. This photonic neuron includes: an excitatory-input photo detector that converts an optical excitatory input signal into a corresponding electrical excitatory input signal; and an inhibitory-input photo detector that converts an optical inhibitory input signal into a corresponding electrical inhibitory input signal. It also includes an electrical neuron that receives the electrical excitatory and inhibitory input signals, and generates an electrical output signal, which includes periodic voltage spikes that are triggered by integration of the electrical excitatory and inhibitory input signals. Finally, the photonic neuron includes a light-emitting output device, which converts the electrical output signal into a corresponding optical output signal.

Abstract: This invention relates to a bridged polyethylene glycol-aliphatic polyester block copolymer, which can be used in the production of delivery carriers for micromolecular chemotherapeutic drugs and nucleic acid drugs. Nanoscale pharmaceutical carriers produced from the bridged block polymer may be subjected to specific degradation under pH environments in tumor tissues or tumor cells so as to change the structure of nanoparticles, enhance cell uptake or intracellular drug release, and improve the sensitivity of tumor cells to drugs.

Abstract: The present disclosure relates to compositions and methods for modulating wound healing and regeneration. More particularly, the present disclosure relates to immunomodulatory agents that promote wound healing and tissue regeneration, and that may be optionally used in combination with synthetic or biomaterial scaffolds.

Abstract: Luminescent solar concentrators in accordance with various embodiments of the invention can be designed to minimize photon thermalization losses and incomplete light trapping using various components and techniques. Cadmium selenide core, cadmium sulfide shell (CdSe/CdS) quantum dot (“QD”) technology can be implemented in such devices to allow for near-unity QDs and sufficiently large Stokes shifts. Many embodiments of the invention include a luminescent solar concentrator that incorporates CdSe/CdS quantum dot luminophores. In further embodiments, anisotropic luminophore emission can be implemented through metasurface/plasmonic antenna coupling. In several embodiments, red-shifted luminophores are implemented. Additionally, top and bottom spectrally-selective filters, such as but not limited to selectively-reflective metasurface mirrors and polymeric stack filters, can be implemented to enhance the photon collection efficiency.

Abstract: An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 214.

Abstract: Nanoarchitectures comprised of subwavelength metal nanosphere oligomers with uniform narrow gap spacings for plasmonic and metamaterial devices are described, as well as methods of fabrication thereof, a biosensor system based thereon, and methods of detection of pathogenic or other organisms (e.g., bacteria) using the same.

Abstract: Described herein are oral care compositions comprising amphiphilic macromolecules, along with methods of making and using same.

Abstract: The present invention relates to a method and tools for manufacturing of seamless tubular shapes, especially tubes and canisters. In the method of the invention the tubular shape is extracted from the flash (1) continuously produced during the plunging of a consumable rod (2) against a rigid anvil (3). The tools of the invention include a consumable rod (2); a non-consumable or consumable rigid anvil (3); first means for rotating the consumable rod (2) and the non-consumable or consumable rigid anvil (3) relatively with respect of each other; second means for plunging the consumable rod (2) and the non-consumable or consumable rigid anvil (3) relatively against each other; open die condition configuration for continuous production of flash (1) during said plunging.

Abstract: The invention features lentiviral transfer vectors that include heterologous nucleic acids to be introduced into a cell. The lentiviral transfer vector may be characterized by the following features: (a) including a cytomegalovirus (CMV) promoter; (b) including a polynucleotide encoding a partial gag protein that includes a mutated INS1 inhibitory sequence that reduces restriction of nuclear export of RNA; (c) not including a polynucleotide encoding the INS2, INS3, and INS4 inhibitory sequences of gag; (d) not including an SV40 origin of replication and/or an f1 origin of replication; (e) including a cPPT sequence that contains splice site; (f) including an EF1 alpha promoter with intact splice donor and acceptor sites; and (g) including hepatitis B PRE with mutation in start codon of X protein ORF.

Abstract: The invention provides mesoporous nanoparticles loaded within its pores with at least one loaded pharmaceutically active agent and at least one capping pharmaceutically active agent chemically coordinated with at least one ligand being boronic acid or derivative thereof on the surface of said pores; compositions comprising such mesoporous nanoparticles and uses thereof.

Abstract: A motion assistance apparatus includes a force transmitting frame having a sliding space therein, the force transmitting frame configured to support a distal part of a user, a slider configured to slide in the sliding space, and a driving frame connected to the slider and configured to slide with respect to a proximal part of the user.

Abstract: A multi-ringed differential microphone array includes a first number of microphones situated along a first substantial circle having a first radius, a second number of microphones situated along a second substantial circle having a second radius, and a processing device, communicatively coupled to the first number microphones and the second number of microphones, to receive a plurality of electronic signals generated by the first number of microphones and the second number of microphones, determine a differential order (N) based on the second number, and execute an N-th order minimum-norm beamformer to calculate an estimate of the sound source based on the plurality of electronic signals.

Abstract: A laser measurement system and method for measuring a six-degree-of-freedom geometric error of a rotating shaft includes a laser emission unit, a six-degree-of-freedom error measurement unit, a six-degree-of-freedom error sensing unit and a servo tracking unit capable of being installed on the rotating shaft to be measured, in which the error measurement unit enables light to be emergent from the error sensing unit and generates a measuring signal according to emergent light and reflected light and backward reflected light of the error sensing unit, and the servo tracking unit includes a four-dimensional adjustment mechanism for realizing four-dimensional adjustment; a motor fixedly installed on the adjustment mechanism; an angle measurement sensor for measuring a rotation angle of the motor; an installation plane fixed on the adjustment mechanism, coaxially rotating with the motor and used for installing the error sensing unit; and a control circuit for controlling the servo tracking unit according to the me