Abstract: This invention relates to use of a platinum-acridine liposomal formulation and uses thereof in treating cancer in a subject.

Abstract: Aspects of the disclosure provide a wireless node in a wireless network with a grid topology for routing a message. The wireless node includes circuitry configured to receive a message including a destination node identification number, calculate a destination column and a destination row based on the destination node identification number, determine a next hop address based on the destination column and the destination row, and transmit the message including the next hop address to a next hop node.

Abstract: This invention proposes a method for part mobility prediction based on a static snapshot. This part mobility prediction method consists of several steps: constructing mobility units from each 3D model in a set of 3D models with parts segmented according to their motion and grouping all of the mobility units according to their motion type; computing snapshot descriptors for every static snapshot in a mobility unit; learning a snapshot-to-unit distance measure for every motion types of the mobility units; getting the most similar mobility unit and its motion type for a query snapshot by using the snapshot-to-unit distance measure to select with the minimum distance value; generating multiple motion candidates for a query static snapshot according to the achieved mobility unit and its motion type, sampling the generated motion and getting the best motion parameter for the query snapshot. This invention can predict the part mobility from a static snapshot of an object.

Abstract: Disclosed are substituted heterocycle compounds including substituted pyrazoles, substituted pyrimidines, and substitute triazoles. The substituted heterocycles disclosed herein are shown to be useful in inhibiting c-MYC and may be utilized as therapeutics for treating cancer and cell proliferative disorders.

Abstract: Disclosed herein are embodiments of methods for encoding, decoding, and matching patterns in collections of signals. These methods use weighting functions to scale the signals. This scaling enables the use of signals of arbitrary duration, wherein the signals may include discrete sequences and spike trains. In the most general case, the signals can be represented using functionals, which extends the expressive power of the methods. Further disclosed herein are embodiments of a system that performs these methods.

Abstract: A solar carport module including a support structure to provide shelter to a vehicle, the support structure having a pair of trusses rotatably affixed to a ground surface on which vehicle is parked, a plurality of photovoltaic panels mounted between the pair of trusses to provide solar electricity, a battery assembly that electrically connects the plurality of photovoltaic panel to receive, regulate, and store the solar electricity, an articulation system that rotates the pair of trusses between a shelter position and a service position, and an electrical control unit configured to detect a maximum sunlight exposure position and to operate the articulation system to place the plurality of photovoltaic panels in the maximum sunlight exposure position.

Abstract: A method for performing an assessment of mental and behavioral condition of a subject includes displaying, by a virtual reality (VR) device, a VR scene; generating, by the VR device, a notification indicating an assignment for the subject in the VR scene; recording, by a recording device, a response of the subject to the assignment; calculating, by a processing device, at least one score based on the response; and comparing, by the processing device, the score with a pre-established normative scale to generate an assessment result for the mental and behavioral condition of the subject.

Abstract: A hydrogel condom containing an antioxidant can provide increased sexual pleasure, thus improving usage and resulting in prevention of disease and prevention of unwanted pregnancies.

Abstract: The present invention relates to a downhole drilling tool system of torque self-balancing and belongs to a technical field of drilling engineering equipment. The drilling tool system consists of an assembly of internal and external drill bits, power components, a pressure adjustment system for internal and external drill bits, a mud circulating system, and an unfreezing system.

Abstract: A behavioral malware detection involves extracting features from prefetch files, wherein prefetch files; classifying and detecting benign applications from malicious applications using the features of the prefetch files; and quarantining malicious applications based on the detection.

Abstract: An electric motor is provided, comprising: a first magnetic component, a second magnetic component, and a circuit configured to electromagnetically activate at least one of the first magnetic component and the second magnetic component. The electromagnetic activation causes a change in a gap between the first magnetic component and the second magnetic component, the change in the gap resulting in rotation of at least one of the first magnetic component and the second magnetic component.

Abstract: The present disclosure provides nucleic acid compositions that incorporate one or more halouracil molecules. More specifically, the present disclosure reveals that the replacement of uracil nucleotides within a microRNA nucleotide sequence with a 5-halouracil increases the ability of the micro-RNA to inhibit cancer progression and tumorigenesis. As such, the present disclosure provides various nucleic acid (e.g., microRNA) compositions having 5-halouracil molecules incorporated in their nucleic acid sequences and methods for using the same. The present disclosure further provides pharmaceutical compositions comprising the modified nucleic acid compositions, and methods for treating cancers using the same.

Abstract: The present invention provides a retraction device comprising, a shaft, a plurality of arms supported by the shaft, the arms being configured to be moveable between a first orientation in which the device assumes an insertion profile for passage of the device through a surgical incision, and a second orientation in which the device assumes a retraction profile. At least one of the plurality of the arms is adapted to be adjustable between a first length and a second length.

Abstract: A water curtain head according to the present invention may comprise: a head body which is connected to a water supply pipe installed in an inner side of a building and has a water-releasing opening; and a deflector arranged adjacent to the water-releasing opening to allow water discharged by the water-releasing opening to pass therethrough. The deflector may comprise: a first spray nozzle formed on the front surface of the deflector to penetrate the front surface of the deflector; and a second spray nozzle formed to be recessed inward from a side surface of the deflector by a predetermined section.

Abstract: The presently disclosed composition and methods are provided for an in situ forming nanofiber-hydrogel composite, which is formed using non-covalent binding schemes between the fiber surface and hydrogel-forming polymers. A method for healing a soft tissue defect can include applying the said composite material to a soft tissue defect.

Abstract: Provided herein are Mycobacterium smegmatis porin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression.

Abstract: A magnetic measuring apparatus includes an inclination gantry including a mount surface and an inclined surface that is inclined with respect to the mount surface, a cryostat disposed on the inclined surface, a cryocooling system connected to the cryostat, a sensor tube connected to the cryostat and including a curved surface that does not curve in a predetermined direction and curves in a direction orthogonal to the predetermined direction such that a center of the curved surface protrudes with respect to side edges of the curved surface, and a magnetic sensor that measures biomagnetism and is housed in the sensor tube such that a sensor surface of the magnetic sensor faces the curved surface. The sensor surface is inclined with respect to the mount surface in a direction that is the same as a direction in which the inclined surface is inclined.

Abstract: In some aspects, the present disclosure provides vaccine compositions comprising an antigen and a diblock copolymer wherein the diblock copolymer is pH responsive. In some embodiments, these compositions activate the STING and/or the interferon receptor pathways. In some embodiments, the diblock copolymer hits a pKa from about 6 to about 7.5. Also provided herein are methods of treatment using these compositions to treat an infectious disease or cancer.

Abstract: A device for in vitro culture of embryos includes: an array having at least one well formed therein; and a bottom surface formed in the well and made of polydimethylsiloxane (PDMS). The use of the culture vessel having the well bottom surface made of PDMS has the effect of further increasing the blastocyst formation rate of embryos compared to the use of conventional arrays made of plastic.

Abstract: The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, said compound having the structure: Formula (I)