Patents Assigned to University
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Patent number: 9571266Abstract: This invention relates to methods and systems for estimating skew based on, for example, the IEEE 1588 Precision Time Protocol (PTP). These methods and systems can allow the clock skew between a master clock (server) and slave clock (client) exchanging PTP messages over a packet network to be estimated. In one embodiment, the slave employs a digital phase-locked loop (DPLL) driven by timestamps supplied from a master clock. The slave is able to process the timestamp information embedded in PTP Sync and Follow_Up messages in order to lock its frequency to that of the master clock. In certain embodiments a frequency locked DPLL and a local free-running counter are used to estimate the skew of the local slave oscillator.Type: GrantFiled: February 25, 2016Date of Patent: February 14, 2017Assignees: British Telecommunications PLC, Khalifa University of Science Technology, and Research, Emirates Telecommunications CorporationInventors: James Aweya, Ivan Boyd
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Patent number: 9566247Abstract: The present invention relates to compositions and methods to treat and/or prevent biofilms and biofilm related diseases. The invention comprises a nanoparticle carrier (NPC) and at least one therapeutic agent therein. The NPC binds within biofilm and to surfaces at risk for biofilm formation and accumulation while providing local, sustained, enhanced and controlled delivery of the therapeutic agent, when triggered for release. In one embodiment, the NPC comprises pH-responsive elements that allows for specific delivery of the therapeutic agent when the local environment dictates that the agent should be delivered precisely when it is most needed.Type: GrantFiled: February 25, 2014Date of Patent: February 14, 2017Assignee: University of RochesterInventors: Hyun Koo, Danielle Benoit, Marlise I. Klein, Megan L. Falsetta Wood
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Patent number: 9566251Abstract: The present invention provides methods for reducing pain in a subject in need thereof by delivering a volatile anesthetic in a solution or an emulsion that can additionally include an extractive solvent in an amount effective to reduce pain without substantially interfering with motor function. Chronic or acute pain may be treated, or the volatile anesthetic may be delivered as a regional anesthetic to a subject to anesthetize a portion of the subject prior to surgery. Dosing regimes including a one-time administration, continuous and/or periodic administration are contemplated.Type: GrantFiled: December 20, 2012Date of Patent: February 14, 2017Assignee: Board of Regents, The University of Texas SystemInventors: Allen Burton, Phillip C. Phan, Hatice Ozsoy, Christopher C. Capelli
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Patent number: 9567648Abstract: The present invention is directed to the detection of problematic foaming and bulking bacterial species in the biological wastewater treatment process. The invention provides various compositions of matter and methods for the detection of foaming and bulking bacterial species and genera in wastewater and other samples. PCR primers capable of amplifying 16s rRNA gene sequences from various foaming and bulking bacterial species are provided, as are probes that will specifically hybridize with PCR amplification products produced by the disclosed primers. In certain embodiments, the use of the disclosed PCR primers and probes in detection assays is disclosed.Type: GrantFiled: February 11, 2016Date of Patent: February 14, 2017Assignee: The Regents of the University of CaliforniaInventors: Betty Olson, Pitiporn Asvapathanagul
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Patent number: 9567257Abstract: The disclosure relates to a method for making a metal nanowire film. The method includes applying a metal layer on a substrate; placing a carbon nanotube composite structure on the metal layer, wherein the carbon nanotube composite structure defines a number of openings and parts of the metal layer are exposed by the number of openings; dry etching the metal layer using the carbon nanotube composite structure as a mask; and removing the carbon nanotube composite structure. The carbon nanotube composite structure includes a carbon nanotube structure and a protective layer coated on the carbon nanotube structure. The carbon nanotube structure includes a number of carbon nanotubes arranged substantially along the same direction.Type: GrantFiled: December 13, 2015Date of Patent: February 14, 2017Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.Inventors: Yuan-Hao Jin, Qun-Qing Li, Shou-Shan Fan
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Patent number: 9569407Abstract: The present invention provides an apparatus for logically processing a composite graph in a formatted document, the apparatus comprising: a composite graph block extraction unit, used to extract a composite graph block in the formatted document; a document parsing unit, used to parse the formatted document to obtain a text element contained therein; a cutline element extraction unit, used to extract a cutline element from the text element; a correlativity detection unit, used to detect correlativity between the composite graph block and the cutline element; a correlativity storage unit, used to store the detected correlativity. The present invention also provides a method for logically processing a composite graph in a formatted document. According to the technical scheme disclosed in the present invention, it is easily achieve layout understanding of the composite graph in a graph-text mixed layout of the formatted document, so as to avoid a logical error.Type: GrantFiled: December 3, 2013Date of Patent: February 14, 2017Assignees: Peking University Founder Group Co., Ltd., Founder Apabi Technology Limited, Peking UniversityInventors: Canhui Xu, Zhi Tang, Xin Tao, Cao Shi
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Patent number: 9566355Abstract: The present invention relates to bacteria-targeted contrast agents for magnetic resonance imaging (MRI). In particular, the present invention relates to bacteria targeted MRI contrast agents that can be used to detect bacteria in vivo or in vitro. In certain embodiments, the contrast agents comprise a metal chelate conjugated to at least two Zn-dipicolylamine groups.Type: GrantFiled: March 6, 2014Date of Patent: February 14, 2017Assignee: Northwestern UniversityInventors: Lauren M. Matosziuk, Allison S. Harney, Keith W. MacRenaris, Thomas J. Meade
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Patent number: 9570487Abstract: An optical output photodetector includes a substrate having a semiconductor surface and at least one optical photodetector element on the semiconductor surface. The optical photodetector element includes a plurality of integrated sensing regions which collectively provide a plurality of different absorbance spectra. The plurality of sensing regions includes a plurality of different semiconductor materials or a semiconductor material having a plurality of different dopants. The optical photodetector element can be configured as an array of optical photodetector elements and the dopants can be magnetic dopants.Type: GrantFiled: February 10, 2014Date of Patent: February 14, 2017Assignees: The United States of America, Naval Undersea Warfare Center, University of Central Florida Research Foundation, Inc.Inventors: Tariq Manzur, Aravinda Kar
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Patent number: 9567402Abstract: In various embodiments various cancer specific antibodies and immunoconjugates are provided. In certain embodiments the antibodies specifically bind and are internalized into a prostate cancer cell, where the antibodies specifically binds cells that express or overexpress a CD46, and where the antibodies specifically bind sushi domain 1 of said CD46 (CD46 CPP1).Type: GrantFiled: March 11, 2014Date of Patent: February 14, 2017Assignee: The Regents of the University of CaliforniaInventor: Bin Liu
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Patent number: 9567305Abstract: The present invention provides oxazine compounds, method of using and method of making oxazine compounds and its pharmaceutical use.Type: GrantFiled: January 20, 2014Date of Patent: February 14, 2017Assignee: Southern Methodist UniversityInventors: Edward R. Biehl, Haribabu Ankati, Sukanta Kamila
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Patent number: 9570684Abstract: Example embodiments relate to methods of doping a 2-dimensional semiconductor. The method includes forming a semiconductor layer on a substrate, implanting ions into the semiconductor layer, forming a doped layer formed of a 2-dimensional semiconductor layer or an organic semiconductor layer on the semiconductor layer, and doping the doped layer by diffusing the ions of the semiconductor layer into the doped layer through annealing the substrate.Type: GrantFiled: July 24, 2014Date of Patent: February 14, 2017Assignees: Samsung Electronics Co., Ltd., Research & Business Foundation Sungkyunkwan UniversityInventors: Jin-hong Park, Hyung-youl Park, Jae-woo Shim, Jae-ho Lee
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Patent number: 9568675Abstract: A waveguide coupler comprising: a first coupling portion arranged to couple with a first waveguide and a second coupling portion arranged to couple with a second waveguide so as to connect the first waveguide and the second waveguide together; wherein arranged between the first and second coupling portions is a wave modulation portion arranged to modulate wave signals transferred between the first waveguide and the second waveguide.Type: GrantFiled: June 6, 2014Date of Patent: February 14, 2017Assignee: City University of Hong KongInventors: Sai Tak Chu, Peng Zhou, Jacky Ping Yuen Tsui
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Patent number: 9571204Abstract: A LED optical communication receiving lens includes a first surface and a second surface opposite to the first surface. The first surface includes a first spherical surface and a second spherical surface connected to the first spherical surface. The second surface includes a third spherical surface and a planar surface connected to the third spherical surface. A position of the LED optical communication receiving lens is defined as a three-dimensional Cartesian coordinate system (x, y, z). Sphere centers and symmetric central points of the first spherical surface, the second spherical surface, and the third spherical surface are located on the x axis. The first spherical surface and the planar surface are transmitted surfaces. The second spherical surface and the third spherical surface are reflective surfaces. The present application also relates to a LED optical communication system including the LED optical communication receiving lens.Type: GrantFiled: July 30, 2015Date of Patent: February 14, 2017Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.Inventors: Jun Zhu, Si-Si Xiong, Xiao-Fei Wu, Tong Yang, Guo-Fan Jin, Shou-Shan Fan
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Patent number: 9566436Abstract: Electrode structures for transvascular nerve stimulation combine electrodes with an electrically-insulating backing layer. The backing layer increases the electrical impedance of electrical paths through blood in a lumen of a blood vessel and consequently increases the flow of electrical current through surrounding tissues. The electrode structures may be applied to stimulate nerves such as the phrenic, vagus, trigeminal, obturator or other nerves.Type: GrantFiled: July 6, 2015Date of Patent: February 14, 2017Assignee: Simon Fraser UniversityInventor: Joaquin Andres Hoffer
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Patent number: 9567369Abstract: A method of treating metastatic cancer, comprising the steps of (a) treating a metastatic cancer patient with an isolated therapeutic Cystatin C peptide, and (b) observing a reduction in tumor burden is disclosed.Type: GrantFiled: July 26, 2013Date of Patent: February 14, 2017Assignee: A.T. Still UniversityInventor: James L. Cox
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Patent number: 9566241Abstract: Stable nanoparticle compositions comprising buprenorphine and at least one biodegradable polymer. The disclosure also provides methods of controlling pain in an animal and methods of treating addiction in a human utilizing the stable nanoparticle compositions, as well as pharmaceutical formulations comprising the stable nanoparticle compositions. The stable nanoparticle compositions are capable of releasing buprenorphine over several days, weeks, or months following administration. The stable nanoparticle compositions of buprenorphine utilize biodegradable polymers capable of degrading into non-toxic components in the body of an animal and may be excreted in the urine of the animal following their metabolism in the body. The stable nanoparticle compositions can advantageously provide sustained release of buprenorphine in the body after a single administration without the need for surgical removal of implanted matrices subsequent to depletion of the drug.Type: GrantFiled: February 21, 2013Date of Patent: February 14, 2017Assignee: Auburn UniversityInventors: William R. Ravis, Yuh-Jing Lin
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Patent number: 9568545Abstract: Systems and methods for precision optical imaging of electrical currents and temperature in integrated circuits are disclosed herein. In one aspect of the disclosed subject matter, a method for detecting a characteristic of an integrated circuit can include depositing at least one diamond structure, having at least one color center therein, onto a side of the integrated circuit.Type: GrantFiled: December 10, 2014Date of Patent: February 14, 2017Assignee: The Trustees of Columbia University in the City of New YorkInventors: Dirk R. Englund, Matthew E. Trusheim
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Patent number: 9569887Abstract: The identification and determination of aspects of the construction of a patient's heart is important for cardiologists and cardiac surgeons in the diagnosis, analysis, treatment, and management of cardiac patients. For example minimally invasive heart surgery demands knowledge of heart geometry, heart fiber orientation, etc. While medical imaging has advanced significantly the accurate three dimensional (3D) rendering from a series of imaging slices remains a critical step in the planning and execution of patient treatment. Embodiments of the invention construct using diffuse MRI data 3D renderings from iterating connections forms derived from arbitrary smooth frame fields to not only corroborate biological measurements of heart fiber orientation but also provide novel biological views in respect of heart fiber orientation etc.Type: GrantFiled: May 14, 2015Date of Patent: February 14, 2017Assignee: The Royal Institution for the Advancement of Learning / McGill UniversityInventors: Kaleem Siddiqi, Emmanuel Piuze-Phaneuf, Jon Sporring
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Patent number: 9566428Abstract: An artificial sensory epithelium (1) to be embedded in a cochlea (301) of a patient includes a piezoelectric film (2) and multitude microelectrodes (3), (3), . . . arranged on the cochlea. The piezoelectric film is arranged along a basilar membrane (306) in the cochlea. A portion of the piezoelectric film that corresponds to a portion of the basilar membrane that is induced to vibrate by sound waves coming from outside the cochlea vibrates. A microelectrode of the microelectrodes that is arranged on the portion of the piezoelectric film provides electric stimuli to spiral ganglion neurons (311). The artificial sensory epithelium preferably includes a support member (4) configured to support the piezoelectric film and be fixable in the cochlea.Type: GrantFiled: August 30, 2013Date of Patent: February 14, 2017Assignee: Osaka UniversityInventors: Satoyuki Kawano, Juichi Ito, Takayuki Nakagawa, Hirofumi Shintaku
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Patent number: 9567592Abstract: In one aspect, the invention provides methods and compositions for the expression of small RNA molecules within a cell using a retroviral vector (FIG. 1A). Small interfering RNA (siRNA) can be expressed using the methods of the invention within a cell. In a further aspect, the invention provides methods for producing siRNA encoding lentivirus where the siRNA activity may interfere with the lentiviral life cycle. In yet a further aspect, the invention provides methods for expression of a small RNA molecule within a cell, such as an siRNA capable of downregulating CCR5, wherein expression of the small RNA molecule is relatively non-cytotoxic to the cell. The invention also includes small RNA molecules, such as an siRNA capable of downregulating CCR5, that are relatively non-cytotoxic to cells.Type: GrantFiled: April 24, 2015Date of Patent: February 14, 2017Assignees: California Institute of Technology, The Regents of the University of CaliforniaInventors: Carlos Lois-Caballe, David Baltimore, Xiao-Feng Qin, Irvin S. Y. Chen, Dong Sung An