Patents Assigned to University
  • Medical image processing apparatus
    Patent number: 9563968
    Abstract: According to an embodiment, a medical image processing apparatus includes an extraction unit, a calculation unit, and a selection unit. The extraction unit extracts an image region having an image element value larger than a predetermined value from a first image of at least one time phase and second images of a plurality of time phases. The calculation unit calculates a feature quantity that fluctuates in accordance with motion of the image region for the first image of at least the one time phase and the second images of the time phases. The selection unit selects the first image and the second image having similar image features of the image region based on the feature quantity from among the first image of at least the one time phase and the second images of the time phases.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: February 7, 2017
    Assignees: Toshiba Medical Systems Corporation, Iwate Medical University
    Inventors: Kimiko Sunami, Kazumasa Arakita, Masahiro Ozaki, Kunihiro Yoshioka, Ryoichi Tanaka, Kenta Muranaka
  • Spraying system and methods of use thereof
    Patent number: 9561514
    Abstract: Embodiments of the present disclosure provide for spraying systems, methods of disposing a layer of matrix onto a sample, and the like.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: February 7, 2017
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Timothy James Garrett, William Pratt Mounfield, III
  • Group of alkaloids, the novel autophagic enhancers for treatment of cancers and neurodegenerative conditions thereof
    Patent number: 9561220
    Abstract: The present invention discloses a method of treating cancer comprising administering an effective amount of an alkaloid, in which the alkaloid is liensinine, isoliensinine, dauricine, cepharanthine, hernandezine or thalidezine and isolated from the traditional Chinese medicinal herbs. The use of the alkaloid in treating neurodegenerative disorder is also disclosed.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: February 7, 2017
    Assignee: Macau University of Science and Technology
    Inventors: Kam Wai Wong, Yuen Kwan Law, Liang Liu, Jingrong Wang
  • Self-assembling peptide cages from coiled-coil peptide modules
    Patent number: 9562074
    Abstract: This invention relates to protein structures, to methods of producing those protein structures, and to peptides used in the formation of the protein structures.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: February 7, 2017
    Assignee: The University of Bristol
    Inventors: Dek Woolfson, Paula Booth, Jordan Fletcher, Richard Sessions, Noah Linden
  • Method of making ultra-high strength stainless steels
    Patent number: 9562274
    Abstract: An ultra-high strength stainless steel alloy with enhanced toughness includes in % by weight: 0 to 0.06% carbon (C); 12.0 to 18% chromium (Cr); 16.5 to 31.0% cobalt (Co); 0 to 8% molybdenum (Mo); 0.5 to 5.0% nickel (Ni); 0 to 0.5% titanium (Ti); 0 to 1.0% niobium (Nb); 0 to 0.5% vanadium (V); 0 to 16% tungsten (W); balance iron (Fe) and incidental deoxidizers and impurities. The heat treating method includes the steps of austenitizing at least once followed by quenching, tempering and sub-zero cooling to obtain no more than about 6-8% retained austenite in the finished alloy.
    Type: Grant
    Filed: September 7, 2011
    Date of Patent: February 7, 2017
    Assignee: Carnegie Mellon University
    Inventor: Warren M. Garrison, Jr.
  • Pyrazolopyrimidine compounds for the treatment of cancer
    Patent number: 9562047
    Abstract: Compounds of Formula I are described, along with pharmaceutically acceptable salts thereof, compositions containing the same, and methods of use thereof.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: February 7, 2017
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Xiaodong Wang, Jing Liu, Chao Yang, Weihe Zhang, Stephen Frye, Dmitri Kireev
  • Haplotying of HLA loci with ultra-deep shotgun sequencing
    Patent number: 9562269
    Abstract: Methods are provided to determine the entire genomic region of a particular HLA locus including both intron and exons. The resultant consensus sequences provides linkage information between different exons, and produces the unique sequence from each of the two genes from the individual sample being typed. The sequence information in intron regions along with the exon sequences provides an accurate HLA haplotype.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: February 7, 2017
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Chunlin Wang, Michael N. Mindrinos, Mark M. Davis, Ronald W. Davis, Sujatha Krishnakumar
  • Apparatus and method for avoiding message collision between V2V communication
    Patent number: 9565705
    Abstract: An apparatus for avoiding a message collision between vehicle to vehicle (V2V) communications may include a channel busy percentage (CBP) determiner configured to determine a CBP and a controller configured to establish a data rate based on the determined CBP. When the CBP exceeds a preset reference value, the controller may adapt the data rate to an upper data rate. A method, system, and computer readable medium are further disclosed for performing the same.
    Type: Grant
    Filed: August 13, 2014
    Date of Patent: February 7, 2017
    Assignees: Hyundai Motor Company, Kia Motors Corporation, Korea University Research and Business Foundation
    Inventors: Dong Gyu Noh, Jong Rok Park, Ji Hun Ha, Yong Tae Park, Hyo Gon Kim, Byung Jo Kim
  • Transition metal complexes supported on metal-organic frameworks for heterogeneous catalysts
    Patent number: 9562118
    Abstract: A robust mesoporous metal-organic framework comprising a hafnium-based metal-organic framework and a single-site zirconium-benzyl species is provided. The hafnium, zirconium-benzyl metal-organic framework is useful as a catalyst for the polymerization of an alkene.
    Type: Grant
    Filed: August 12, 2015
    Date of Patent: February 7, 2017
    Assignee: Northwestern University
    Inventors: Omar K. Farha, Joseph T. Hupp, Massimiliano Delferro, Rachel C. Klet
  • Methods for production of fatty acid alkanolamides (FAAAs) from microalgae biomass
    Patent number: 9562210
    Abstract: Provided herein are methods for fatty acid alkanolamide (FAAA) synthesis and isolation from lipid-containing algal biomass, and the products of such methods.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: February 7, 2017
    Assignee: The University of Toledo
    Inventors: Kana Yamamoto, Sridhar Viamajala, Sasidhar Varanasi, Ajith Yapa Mudiyanselage, Pramod Prasad Poudel
  • Group of alkaloids, the novel autophagic enhancers for treatment of cancers and neurodegenerative conditions thereof
    Patent number: 9561222
    Abstract: The present invention discloses a method of treating cancer comprising administering an effective amount of an alkaloid, in which the alkaloid is liensinine, isoliensinine, dauricine, cepharanthine, hernandezine or thalidezine and isolated from the traditional Chinese medicinal herbs. The use of the alkaloid in treating neurodegenerative disorder is also disclosed.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: February 7, 2017
    Assignee: Macau University of Science and Technology
    Inventors: Kam Wai Wong, Yuen Kwan Law, Liang Liu, Jingrong Wang
  • STAT3 inhibitor
    Patent number: 9562002
    Abstract: Provided are STAT3 inhibitors and methods of treating inflammation or a hyperproliferative disease such as, e.g., cancer. In some aspects, compounds may be used to treat breast cancer, a head/neck cancer, a lung cancer, a prostate cancer, or pancreatic cancer.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: February 7, 2017
    Assignee: Board of Regents, The University of Texas System
    Inventors: Jia Zhou, Haijun Chen, Qiang Shen
  • Combination treatments for melanoma
    Patent number: 9561245
    Abstract: The present invention relates to combination therapies for melanoma, and in particular, metastatic melanoma. Drugs for use in such therapies in include BRAF inhibitors such as PLX 4720 and PLX 4734 in combination with RO 31-8220, bafetinib or cardiac glycosides.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: February 7, 2017
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Sean Morrison, Elena Piskounova, Ugur Eskiocak
  • OPTICAL POLARIZATION TRACTOGRAPHY SYSTEMS, METHODS AND DEVICES
    Publication number: 20170031143
    Abstract: High-resolution 3D optical polarization tractography (OPT) images of the internal fiber structure of a target tissue. Manipulation of dual-angle imaging data of the fiber orientation inside a target tissue leads to the determination of 3D imaging properties of the target tissue, allowing transmission of the 3D image properties of the target tissue to an OPT processor to produce high-resolution 3D images.
    Type: Application
    Filed: July 29, 2016
    Publication date: February 2, 2017
    Applicant: The Curators of the University of Missouri
    Inventors: Gang Yao, Dongsheng Duan, Yuanbo Wang
  • ALLENAMIDE AS AN ORTHOGONAL HANDLE FOR SELECTIVE MODIFICATION OF CYSTEINE IN PEPTIDES AND PROTEINS
    Publication number: 20170029373
    Abstract: There is provided a compound of formula I, having the structure: wherein R1 to R5 have the meanings given in the description.
    Type: Application
    Filed: March 27, 2015
    Publication date: February 2, 2017
    Applicant: Nanyang Technological University
    Inventors: Ata Abbas, Teck Peng Loh, Bengang Xing
  • SYSTEM & METHOD FOR ESTIMATING SUBSTANCE CONCENTRATIONS IN BODILY FLUIDS
    Publication number: 20170027486
    Abstract: One implementation described herein includes a system for providing at least an estimate of substance concentrations in a bodily fluid. The system comprises a first emitter for generating signals using a first sensing modality, a first detector configured to detect signals from said first emitter that have travelled through the bodily fluid and output a corresponding first detector signal; a second emitter for generating signals using a second sensing modality different to said first sensing modality, a second detector configured to detect signals from said second emitter that have travelled through the bodily fluid and output a corresponding second detector signal; and a processor configured to receive the detector signals from said first and second detectors, to process said signals and to output an indication of at least an estimate of the concentration of said substance in said bodily fluid.
    Type: Application
    Filed: April 7, 2015
    Publication date: February 2, 2017
    Applicant: The City University
    Inventors: Panayiotis Kyriacou, Meha Qassem, Loukas Constantinou, Iasonas Triantis, Michelle Hickey
  • LIPOSOMAL MUPIROCIN
    Publication number: 20170027869
    Abstract: Provided are liposomes encapsulating mupirocin, with particular benefit for systemic therapeutically effective delivery. Also provided herein are pharmaceutical compositions including the liposomes and methods of using them. The liposomes include a lipid membrane and an intraliposomal compartment, the intraliposomal compartment encapsulating mupirocin, at least one cyclodextrin compound and a pH dependent ionizable anion, e.g. acetate.
    Type: Application
    Filed: April 8, 2015
    Publication date: February 2, 2017
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Yechezkel BARENHOLZ, Amiram GOLDBLUM, Ahuva CERN
  • SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS
    Publication number: 20170027890
    Abstract: Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.
    Type: Application
    Filed: September 8, 2016
    Publication date: February 2, 2017
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Hoffmann-La Roche Inc.
    Inventors: Uri BEN-DAVID, Nissim BENVENISTY, Payal ARORA, Qing-Fen GAN, Ralph J. GARIPPA
  • ANTICANCER AGENT AND SIDE-EFFECT-ALLEVIATING AGENT
    Publication number: 20170028065
    Abstract: The purpose of the present invention is to provide an anticancer agent for potentiating an antitumor effect, alleviating side effects, and further extending the survival rate by concomitant use with a component having an anticancer effect. An anticancer agent combining arctigenin and a component other than arctigenin that has an anticancer effect, in which the anticancer agent may be a combination drug or may be a kit configured from a formulation containing arctigenin and a formulation containing a component that has an anticancer effect, and the concomitant use of arctigenin and the component having an anticancer effect more strongly inhibits tumor growth and reduces the proportion of cancer stem cells in the tumor, making it possible to extend the total survival time and to alleviate side effects caused by the component having an anticancer effect.
    Type: Application
    Filed: April 10, 2015
    Publication date: February 2, 2017
    Applicants: National University Corporation University of Toyama, Kracie Pharma, Ltd., National Cancer Center, Tokyo University of Science Foundation
    Inventors: Hiroyasu Esumi, Kouji IKEDA, Katsuya TSUCHIHARA, Shigeki Chiba, Satoshi Yomoda, Takanori Kawashima, Toshiki Okubo, Yasuhiro TEZUKA, Kenta MURATA
  • COMPOSITIONS AND METHODS FOR INDUCTION OF TH17 CELLS
    Publication number: 20170028061
    Abstract: Strains of human-derived bacteria have been obtained from complex fecal samples and shown to induce accumulation of Th17 cells in the intestine and promote immune functions. Pharmaceutical compositions containing these bacteria can be used as anti-infectives and as adjuvants in mucosal vaccines.
    Type: Application
    Filed: April 10, 2015
    Publication date: February 2, 2017
    Applicants: RIKEN, The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institution
    Inventors: Kenya Honda, Koji Atarashi, Masahira Hattori, Hidetoshi Morita