Patents Assigned to University
  • Bidirectional gear, method, and applications
    Patent number: 9556947
    Abstract: A bidirectional gear set includes a male bidirectional gear component having an array of addendum teeth and a female bidirectional gear component having an array of dedendum sockets, wherein each dedendum socket has a full boundary edge around an open end thereof. One or both of the male and female gear components may have a circular cross sectional geometry, or one may have a non-circular cross sectional geometry. The non-circular cross sectional geometry may be a flat sheet or a sheet with surface contour. In an intermeshed state, neither the male nor the female component can ‘slide’ relative to the other regardless of whether the male and female components are arranged in a parallel or perpendicular orientation. A method of making a bidirectional gear set is disclosed.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: January 31, 2017
    Assignee: Cornell University
    Inventors: Jonathan Hiller, David A. Hjelle, Hod Lipson, Franz Nigl
  • Treatment for pancreatic cancer
    Patent number: 9555042
    Abstract: The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: January 31, 2017
    Assignee: University Health Network
    Inventors: David W. Hedley, Ines Lohse, Jacqueline M. Mason, Mark R. Bray
  • TCR mimic antibodies as vascular targeting tools
    Patent number: 9555108
    Abstract: The present invention includes a method of delivering a therapeutic agent into and across an endothelial cell (EC) in a subject in need thereof, comprising: attaching to a T Cell receptor mimic (TCR mimic) an active agent to form a therapeutic agent; and administering to the subject the therapeutic agent in a pharmaceutically acceptable carrier, wherein the therapeutic agent effectively crosses the EC microvascular barrier. Furthermore, the present invention relates to methods of treating diseases (particularly neuronal diseases) or conditions comprising identifying a subject in need of such a treatment and administering to said subject a composition comprising a TCR mimic conjugated to an active agent.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: January 31, 2017
    Assignee: Texas Tech University System
    Inventors: John A. Weidanz, Ulrich Bickel
  • Home medication manager
    Patent number: 9554969
    Abstract: A portable self medication management system and method of provided. For example, the system may include a removable tote and docking station. The removable tote including a plurality of receptacles, communicating section for transferring data to and from a docking station and a power reception station for receiving power from the docking station. The docking station including a scanner, a display screen, a controller, a storage device, communicating sections for transmitting data to the removable tote and other external devices and a power transmitting section for transferring power to the removable tote.
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: January 31, 2017
    Assignee: The Research Foundation for The State University of New York
    Inventors: Craig Lehmann, John Brittelli, Chang Hong Chen, Tim Kehoe, Robert Barnikel
  • Synthesis and analysis of compounds capable of inducing differentiation of human mesenchymal stems cells into hepatocytes
    Patent number: 9555061
    Abstract: The invention relates to low-molecular-weight compounds which are capable of inducing differentiation of mesenchymal stem cell into hepatocytes.
    Type: Grant
    Filed: April 2, 2012
    Date of Patent: January 31, 2017
    Assignees: National University Corporation Torrori University, Tokyo Women's Medical University
    Inventors: Goshi Shiota, Yoshiko Hoshikawa, Noriko Matsumoto, Yoshiaki Matsumi, Minoru Morimoto, Takayuki Tonoi, Hiroyuki Saimoto, Kazuo Ohashi, Teruo Okano
  • Manganese-oxo clusters as contrast agents for magnetic resonance imaging
    Patent number: 9555134
    Abstract: Nanoparticles for use as magnetic resonance imaging contrast agents are described. The nanoparticles are made up of a polymeric support and a manganese-oxo or manganses-iron-oxo cluster having magnetic properties suitable of a contrast agent. The manganese-oxo clusters may be Mn-12 clusters, which have known characteristics of a single molecule magnet. The polymer support may form a core particle which is coated by the clusters, or the clusters may be dispersed within the polymeric agent.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: January 31, 2017
    Assignee: Georgetown University
    Inventors: Sarah Stoll, Julie Mertzman, Edward Van Keuren, Christopher Albanese, Stanley Fricke
  • System and method for configuring the remote control functionality of a portable device
    Patent number: 9558654
    Abstract: A system and method used to configure a smart device to command functional operations of a target appliance. The smart device retrieves from a controllable appliance, such as a settop box, data indicative of a codeset identity of the target appliance wherein the codeset identity was determined during a process used to configure a conventional universal remote control to command functional operations of the target appliance and wherein the process used to configure the conventional universal remote control is performed in cooperation with the controllable appliance. A remote control application resident on the smart device then uses the data indicative of the codeset identity retrieved from the controllable appliance to also configure the smart device to command functional operations of the target appliance.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: January 31, 2017
    Assignee: Universal Electronics Inc.
    Inventors: Paul D. Arling, Patrick H. Hayes, Arsham Hatambeiki
  • Method and system for providing a game theory based global routing
    Patent number: 9558313
    Abstract: A system and method for global routing that includes receiving nets that need to be routed and capacity constraints, ordering, using processing circuitry, the nets, routing, using the processing circuitry, the nets based on a maze routing with framing method, determining, using the processing circuitry, whether the routing is congestion free, selecting, using the processing circuitry, a subset of the nets based on a game theory method when the routing is not congestion free, applying a rip-up and re-route process on the subset of the nets, and repeating the selecting and applying steps until the routing is congestion free.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: January 31, 2017
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Umair Farooq Siddiqi, Sadiq M. Sait
  • Methods, systems, and computer readable media for source and listener directivity for interactive wave-based sound propagation
    Patent number: 9560439
    Abstract: Methods, systems, and computer readable media for supporting source or listener directivity in a wave-based sound propagation model are disclosed. According to one method, the method includes computing, prior to run-time, one or more sound fields associated with a source or listener position and modeling, at run-time and using the one or more sound fields and a wave-based sound propagation model, source or listener directivity in an environment.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: January 31, 2017
    Assignee: The University of North Carolina at Chapel Hills
    Inventors: Ravish Mehra, Lakulish Shailesh Antani, Dinesh Manocha
  • Allosteric modulators of CB1 cannabinoid receptors
    Patent number: 9556118
    Abstract: The present invention relates to novel heterocyclic derivatives which are allosteric modulators of cannabinoid receptor 1 (CB1) and which are useful for the treatment or prevention of neurological and psychiatric disorders associated with endocannabinoid dysfunction and diseases in which the CB1 subtype of cannabinoid receptor is involved; to processes for their preparation; to pharmaceutical compositions comprising them; and to methods of using them.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: January 31, 2017
    Assignee: Northeastern University
    Inventors: Ganeshsingh A. Thakur, Pushkar M. Kulkarni
  • Controlled synthesis of bright and compatible lanthanide-doped upconverting nanocrystals
    Patent number: 9556379
    Abstract: Certain nanocrystals possess exceptional optical properties that may make them valuable probes for biological imaging, but rendering these nanoparticles biocompatible requires that they be small enough not to perturb cellular systems. This invention describes a phosphorescent upconverting sub-10 nm nanoparticle comprising a lanthanide-doped hexagonal ?-phase NaYF4 nanocrystal and methods for making the same.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: January 31, 2017
    Assignee: The Regents of the University of California
    Inventors: Bruce E. Cohen, Alexis D. Ostrowski, Emory M. Chan, Daniel J. Gargas, Elan M. Katz, P. James Schuck, Delia J. Milliron
  • Carboxylic acid ester prodrug inhibitors of MEK
    Patent number: 9556112
    Abstract: The invention generally relates to compounds having structure I: wherein x represents alkyl, aryl or het-aryl, each of y independently represents hydrogen or halogen and z represents hydrogen or alkyl. Further, said compounds are inhibitors of MEK 1, 2 and 5. Furthermore, the invention includes methods of making said compounds, compositions including said compounds and uses for inhibiting MEK 1, 2 and 5.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: January 31, 2017
    Assignee: Duquesne University of the Holy Ghost
    Inventors: Suravi Chakrabarty, Darlene Monlish, Patrick Flaherty, Jane E. Cavanaugh, Sneha Potdar
  • Baluster connector
    Patent number: 9556641
    Abstract: A baluster connector for interconnecting a baluster with a hollow end to a portion of a railing system by a fastener having a shaft and a head. The body portion can have an opening of sufficient size to pass the head of the fastener toward the second end of the body to seat against a necked-down portion within the interior of the body. Biasing flanges can extend away from the body to provide resistance when the body is positioned within a hollow end of a baluster.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: January 31, 2017
    Assignee: Universal Consumer Products, Inc.
    Inventor: Daniel J. Milanowski
  • Methods for diagnosing human immunodeficiency virus infections
    Patent number: 9556494
    Abstract: Provided is a method for identifying human immunodeficiency virus (HIV) in a sample. The invention involves use of a plurality of fluorescently labeled oligonucleotide probes and flow cytometry to detect the presence or absence of HIV in macrophages that are obtained from a mucosal surface. The invention is particularly useful for detecting HIV infection prior to seroconversion.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: January 31, 2017
    Assignees: Cornell University, Liverpool School of Tropical Medicine
    Inventors: David G. Russell, Henry Mwandumba, Kondwani Jambo
  • Rice comprising an RC responsive promoter driving expression of a heterologous nucleic acid molecule
    Patent number: 9556446
    Abstract: The present invention relates to rice plants, seeds, and cells that include a promoter responsive to a basic helix-turn-helix red anthocyanin transcription factor operably linked to a heterologous nucleic acid molecule.
    Type: Grant
    Filed: September 14, 2006
    Date of Patent: January 31, 2017
    Assignee: Cornell University
    Inventors: Susan McCouch, Megan Sweeney
  • Polyvalent chimeric OSPC vaccinogen and diagnostic antigen
    Patent number: 9556239
    Abstract: A chimeric polyvalent recombinant protein for use as a vaccine and diagnostic for Lyme disease is provided. The chimeric protein comprises epitopes of the loop 5 region and/or the alpha helix 5 region of outer surface protein C (OspC) types. The OspC types may be associated with mammaliran Borrelia infections.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: January 31, 2017
    Assignee: Virgina Commonwealth University
    Inventors: Richard T. Marconi, Christopher Earnhart
  • Method of forming oxide thin film and method of fabricating oxide thin film transistor using hydrogen peroxide
    Patent number: 9558941
    Abstract: Provided are a method of forming an oxide thin film using hydrogen peroxide, and a method of fabricating an oxide thin film transistor using hydrogen peroxide. Embodiments of the present disclosure provide methods of forming an oxide film, including: mixing hydrogen peroxide with a precursor solution in which a precursor material is dissolved in a solvent; applying the precursor solution mixed with the hydrogen peroxide to a substrate; heat treating the substrate.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: January 31, 2017
    Assignee: Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Hyun Jae Kim, Jeong Moo Kwon
  • Compositions and methods for reducing oxidative damage
    Patent number: 9555054
    Abstract: Polymeric compositions are provided that include a poly(ethylene glycol), a viscoelastic polymer, and an antioxidant, where, in polymerized form, the compositions have a refractive index of about 1.30 to about 1.40. Methods of synthesizing the compositions are also provided and include the steps of heating an amount of water; adding a buffering agent to the water to form a buffer solution; mixing a poly(ethylene glycol) and a viscoelastic polymer into the buffer solution to form a reactive mixture; adding a plurality of antioxidant particles to the reactive mixture; and removing suspended gas bubbles from the reactive mixture. Methods of preventing oxidative damage to an eye lens of a subject are further provided and include administering the foregoing polymeric compositions to the eye lens of the subject.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: January 31, 2017
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Tongalp H. Tezel, Andrea S. Gobin, Martin G. O'Toole
  • Polymer coated sand and methods of manufacture and use
    Patent number: 9555454
    Abstract: Described herein are systems for manipulating a flowable substance, comprising: a flowable substance; a heating means; a cooling means; and a composition comprising chemically inert particles coated with a stimuli-responsive material. Compositions and methods for using the compositions are also described herein.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: January 31, 2017
    Assignee: Lehigh University
    Inventors: Sibel Pamukcu, Yi Dong
  • Vinyl terminated macromonomers
    Patent number: 9556287
    Abstract: Polymers produced by a process comprising contacting one or more olefins with a catalyst system comprising an activator and a Salan catalyst disposed on a support.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: January 31, 2017
    Assignees: ExxonMobil Chemical Patents Inc., Ramot at Tel-Aviv University Ltd.
    Inventors: Garth R. Giesbrecht, Matthew W. Holtcamp, Gregory S. Day, John R. Hagadorn