Abstract: A method for preparing a GaN substrate material includes: performing in-situ epitaxy on a Ga2O3 thin film and a GaN thin film in a multifunctional HVPE growth system. First, the Ga2O3 thin film is grown on a substrate such as sapphire by an HVPE-like method, and the Ga2O3 is nitrided in an ammonia gas atmosphere to form a GaN/Ga2O3 composite thin film. Then, a GaN thick film is grown on the GaN/Ga2O3 composite thin film by HVPE to obtain a high-quality GaN thick film material. The Ga2O3 layer is removed by chemical etching to obtain a self-supporting GaN substrate material. Or, the conventional laser lift-off method is used to separate the GaN thick film from the heterogeneous substrate such as the sapphire to obtain a GaN self-supporting substrate material.

Abstract: The present disclosure as disclosed in various embodiments is related to glueocorticoid compositions and glucocorticoid therapies for treating hematologic or other malignancies, methods and compositions for enhancing the chemotherapeutic effect of glucocorticoids, methods for determining early relapse of a hematologic or other malignancy in a subject, and methods for treating relapse of a hematologic or other malignancy in a subject.

Abstract: The present invention provides a pharmaceutical composition for treating or preventing a cognitive disease or disorder, comprising a compound represented by Formula (I), an enantiomer thereof a diastereomer thereof, or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure provides ?2?-1 C-terminal domain mimetics for the treatment of pain, epilepsy or other disorders in a subject. Further provided is an ?2?-1 C-terminal domain peptide which blocks binding of ?2?-1 to the glutamate receptors NMDAR and AMPAR.

Abstract: A map generation system includes a server configured to: transfer reference curved road constituent points onto a measurement target curved road as virtual constituent points arranged along the measurement target curved road adjacent to the reference curved road; acquire virtual trajectory curvature information based on positions of the virtual constituent points; acquire detailed curve information of the measurement target curved road by acquiring, based on a position of a start point of the measurement target curved road preset in the road map information, travel information of a vehicle traveling on the measurement target curved road, and the virtual trajectory curvature information, measurement target curved road constituent points arranged at preset intervals from the start point along the measurement target curved road, and associating the virtual trajectory curvature information with each of the measurement target curved road constituent points; and generate a map by acquiring the second detailed curve

Abstract: Systems and methods for using near-field inductive coupling between an implanted system and an external transceiver are discloses. In several embodiments, the data link system is based on a free-running oscillator tuned by coupled resonators. The use of an oscillator-based power link can allow for stable power over different inductor distances, or coil distances. In some embodiments, the data link system includes receivers on both sides of the link, where each receiver is composed of a detector, such as but not limited to an analog front-end (“AFE”), and a clock and data recovery (“CDR”) loop.

Abstract: The present invention provides a nanocomplex comprising at least one agent and a nanocarrier. The agent is bound to the nanocarrier. The nanocarrier comprises at least one cationic polymer responsive to a stimulus, at least one anionic polymer and at least one lipid. The agent is capable of being released from the nanocarrier upon exposure to the stimulus. The released agent is active. The nanocomplex may be used to deliver the agent into cells, in which the agent may be released from the nanocarrier upon exposure of the cells to the stimulus.

Abstract: Photoelectrochemical cells including a cathode including alpha-hematite and a metal dichalcogenide, an anode including a conducting polymer, and an electrolyte.

Abstract: A method for treating an inflammatory respiratory disease, comprising administering an effective amount of an RXR agonist represented by formula (1) or (2) as an active ingredient. wherein D, R1, R2, X, Y, Z, R3, R4, X1, Y1, X2, Y2 and Z1 are defined.

Abstract: A membrane distillation module with a circulating line to circulate a portion of distilled water, which is formed and accumulated in a distillate zone, to enhance a permeate flux of water vapor through a hydrophobic membrane of the membrane distillation module. Various combinations of embodiments of the membrane distillation module are provided.

Abstract: A system, method and non-transient computer readable medium for assessing the opportunity to address either hyperglycemic or hypoglycemic risk (or both) in patients with diabetes based on historical continuous glucose monitoring (CGM) data.

Abstract: Various aspects of the present invention provide an apparatus and a method of removing an orthopedic implant from a patient. In one embodiment, the method includes cycling the temperature of at least a portion of the orthopedic implant between a first temperature and a second temperature that differs from the first temperature. In one embodiment, the first temperature is above 0° C. and the second temperature is below 0° C. The temperature cycling causes a thermal expansion differential between at least a portion of the orthopedic implant and material in a region contacting the orthopedic implant. In one embodiment, the thermal expansion differential is of an extent sufficient to cause physical separation of at least a portion of the surface of the orthopedic implant from material contacting the surface of the orthopedic implant.

Abstract: An electrode structure includes a mesh substrate and a nanomaterial. The nanomaterial contains oxide of group IVA element and grows on the mesh substrate. A method of manufacturing the electrode structure and a rechargeable battery including the electrode structure are also provided.

Abstract: A method of making a structural lightweight and thermal insulating concrete is described. The concrete has a coarse aggregate partly replaced by recycled plastic pieces. This enables the concrete to maintain a high compressive strength, low thermal conductivity, and low weight, while providing a use for waste plastic. The waste plastic pieces may comprise polyethylene in the form of flakes, fibers, or granules. Due to its low unit weight, adequate compressive strength and high thermal resistance the developed concrete can be used as a structural lightweight and thermal insulating concrete. The use of this concrete leads to economic and environmental benefits.

Abstract: Provided is a liquid droplet collection device including: a substrate having a hydrophobic surface; and a hydrophilic channel arranged in the hydrophobic surface, wherein the hydrophilic channel includes: a first-generation channel including a plurality of tapered channel portions radially extending from an origin point and monotonically tapering with increasing distance from the origin point; and a second-generation channel that includes a plurality of tapered channel portions radially extending from an origin point and monotonically tapering with increasing distance from the origin point, and is scaled down in size as compared to the first-generation channel, wherein the second-generation channel is joined to the first-generation channel to face the same direction as the first-generation channel, and wherein one of the tapered channel portions of the second-generation channel overlaps a distal end portion of one of the tapered channel portions of the first-generation channel, and the hydrophilic channel mon

Abstract: A coiled tubing drilling robot, a robot system and a process parameter control method thereof. The coiled tubing drilling robot is mainly characterized in that a drilling pressure and a drilling speed of a drill string are adjusted by an electric proportional relief valve and an electric proportional flow valve disposed inside the drilling robot; a support mechanism of the drilling robot adopts a single oblique block to prop against a spring piece to clamp a well wall; the coiled tubing drilling robot system consists of a coiled tubing intelligent drilling rig, a wellhead device, a coiled tubing, a drilling robot, a drill string vibration measurement device, a MWD, a power drill and a drill bit.

Abstract: The present invention relates to recombinant self-assembling protein nanoparticles presenting an albumin-binding peptide at the surface. For the recombinant self-assembling protein nanoparticles according to the present invention, an albumin-binding peptide can reduce the immunogenicity of the recombinant self-assembling protein nanoparticles because the albumin-binding peptide is presented at the surface, and thus binds to an albumin protein present in vivo, and the albumin-binding peptide can also provide the cancer delivery function of the recombinant self-assembling protein nanoparticles because the albumin-binding peptide binds to albumin around cancer. Simultaneously, the binding of the albumin-binding peptide to albumin can significantly increase the in vivo residence time of the recombinant self-assembling protein nanoparticles, thus increasing the potential for use in various medical applications.

Abstract: The present invention provides a preparation method of tobacco sheets with a reduced quantity of wood pulp fibers, and belongs to the technical field of reconstituted tobacco. The method includes the steps of: cooking tobacco stem materials by alkaline process, and filtering and washing the cooked tobacco stem materials to obtain tobacco stem fibers; generating mixed pulp by mixing wood pulp fibers, tobacco pulp, filling materials, water and the tobacco stem fibers together as per certain proportions, and subjecting the mixed pulp to a papermaking process in a paper machine to obtain tobacco sheets. By means of adding tobacco stem fibers, the present invention effectively reduces the quantity of wood pulp fibers, ensures the continuous operation of the paper machine, and effectively improves the bulk and tensile index of prepared tobacco sheets.

Abstract: In some aspects, the disclosure relates to compositions and methods of engineering a transgene. In some embodiments, the disclosure provides self-regulating recombinant nucleic acids, viral vectors and pharmaceutical compositions comprising a MeCP2 transgene. In some embodiments, compositions and methods described by the disclosure are useful for treating diseases and disorders associated with a loss of function mutation, for example Rett syndrome.

Abstract: Among the various aspects of the present disclosure is the provision of compositions and methods for mapping transposon insertions. Applications can include mapping the locations of self-reporting transposons (SRTs) from thousands of single cells in parallel, while simultaneously measuring mRNA abundance from the same single cells; analyzing genome-associated protein (GAP) (e.g., transcription factor) binding/interactions in a small number of cells in bulk, without single cell resolution; lineage tracing; or as an improved readout for transposon mutagenesis screens.