Patents Assigned to University
  • Methods and compositions for the diagnosis and prognosis of cervical intraepithelial neoplasia and cervical cancer
    Patent number: 8957039
    Abstract: The invention provides methods and compositions for the diagnosis and prognosis of cervical intraepithelial neoplasia and cervical cancer. The methods comprise the step of determining the expression levels or genetic status of specific miRNAs.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: February 17, 2015
    Assignees: CapitalBio Corporation, Tsinghua University
    Inventors: Wenyan Qin, Peng Dong, Tuo Deng, Cailing Ma, Keith Richard Mitchelson, Hao Wen, Jing Cheng
  • Extracranial implantable devices, systems and methods for the treatment of neuropsychiatric disorders
    Patent number: 8958880
    Abstract: The present disclosure relates to methods, devices, and systems used for the treatment of mood, anxiety, cognitive, and behavioral disorders (collectively, neuropsychiatric disorders) via stimulation of the superficial elements of the trigeminal nerve (“TNS”). More specifically, minimally invasive systems, devices and methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: February 17, 2015
    Assignees: The Regents of the University of California, Neurosigma, Inc.
    Inventors: Christopher DeGiorgio, Ian A. Cook, Leon Ekchian
  • Iminosugar treatment of tumors
    Patent number: 8957106
    Abstract: A proliferation of cells can be reduced by contacting the cells with a compound having formula (I) where R and R? are each alkyl groups, R? is hydrogen or an alkyl group and X3, X4 and X5 are each independently selected from the group consisting of hydrogen, benzyl, t-butyldimethylsiloxy radical and triphenylmethyl. Accordingly, compounds of formula (I) can be used for treatment of tumors including melanoma. Also a secretion of a matrix metalloproteinase (MMP) enzyme by cells can be reduced by contacting the cells with the compound having formula (I). Accordingly, compounds of formula (I) can be used for treatment physiological conditions associated with an elevated MMP level, such as tumors.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: February 17, 2015
    Assignee: The Chancellor, Masters and Scholars of the University of Oxford
    Inventors: Raymond Dwek, Wanda Buzgariu, Anca Hirtopeanu, Robert Moriarty, Gabriela Negroiu, Norica Nichita, Livia Zdrentu, Nicole Zitzmann
  • Thermoacoustic device
    Patent number: 8958579
    Abstract: A thermoacoustic device includes a substrate, a sound wave generator and a signal device. The substrate has a net structure and includes a number of first wires and a number of second wires. The first wires and the second wires are crossed with each other. Each of the first wires includes a composite wire. The composite wire includes a carbon nanotube wire structure and a coating layer wrapping the carbon nanotube wire structure. The sound wave generator is located on a surface of the substrate and includes a carbon film. The signal input device is configured to input signals to the sound wave generator.
    Type: Grant
    Filed: December 26, 2011
    Date of Patent: February 17, 2015
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Kai-Li Jiang, Xiao-Yang Lin, Lin Xiao, Shou-Shan Fan
  • Automated mapping of land cover using sequences of aerial imagery
    Patent number: 8958603
    Abstract: A system has an aerial image database containing sensor data representing a plurality of aerial images of an area having multiple sub-areas. A processor applies a classifier to the sensor values to identify a label for each sub-area in each aerial image and to thereby generate an initial label sequence for each sub-area. The processor identifies a most likely land cover state for each sub-area based on the initial label sequence, a confusion matrix and a transition matrix. For each sub-area, the processor stores the most likely land cover state sequence for the sub-area.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: February 17, 2015
    Assignee: Regents of the University of Minnesota
    Inventors: Shyam Boriah, Ankush Khandelwal, Vipin Kumar, Varun Mithal, Karsten Steinhaeuser
  • Piezoelectric material, piezoelectric element, liquid discharge head, ultrasonic motor, and dust removing device
    Patent number: 8955947
    Abstract: Provided is a piezoelectric material which has satisfactory insulation property and piezoelectric property and which does not contain lead and potassium. The piezoelectric material includes a perovskite-type metal oxide that is represented by the following general formula (1): (NaxBa1-y)(NbyTi1-y)O3??General formula (1) where relationships of 0.80?x?0.95 and 0.85?y?0.95 are satisfied, and y×0.05 mol % or more to y×2 mol % or less of copper with respect to 1 mol of the perovskite-type metal oxide.
    Type: Grant
    Filed: February 27, 2012
    Date of Patent: February 17, 2015
    Assignees: Canon Kabushiki Kaisha, University of Yamanashi
    Inventors: Takayuki Watanabe, Shunsuke Murakami, Nobuhiro Kumada
  • LED package and fabrication method of the same
    Patent number: 8957448
    Abstract: An LED package and method thereof include an insulation plate, and a metal board disposed on the insulation plate and etched to form a cavity, wherein the metal board is etched to partially expose the insulation plate to form the cavity. The LED package and method also include an LED chip configured to be mounted inside the cavity, and an encapsulation member filling the cavity, wherein the encapsulation member comprises an epoxy resin. The LED package and method include a through-hole configured to be formed on the insulation plate where the LED chip is mounted. The through-hole enables portions of the LED chip to be exposed, and a metal configured to fill the through-hole to form an electrode to be electrically connected to the LED chip.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: February 17, 2015
    Assignee: Sungkyunkwan University Foundation for Corporate Collaboration
    Inventors: Su Jeong Suh, Haw Sun Park
  • Compound and organic device employing same
    Patent number: 8957236
    Abstract: The compounds represented by the following general formula have excellent properties as a charge transport material. In the formula, R1 to R3 represent a substituent, n1 and n2 indicate an integer of from 0 to 5, n3 indicates an integer of from 0 to 4, X represents a linking group of —O—, —S—, —SO2—, —CS—, —R4—, —C(R5)(R6)—, —PO(R7)—, —Si(R8)(R9)—, >PO—, >Si(R10)— or >Si<, m is an integer of from 2 to 4, R4 represents an aliphatic cyclic linking group, and R5 to R10 represent a hydrogen atom, an alkyl group, an aryl group, etc.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: February 17, 2015
    Assignee: Kyushu University National University Corporation
    Inventors: Qisheng Zhang, Chihaya Adachi, Shigeyuki Matsunami, Kei Sakanoue
  • Power voltage supply apparatus for three dimensional semiconductor
    Patent number: 8957529
    Abstract: Provided is a power voltage supply apparatus of a 3-dimensional (3D) semiconductor. The power voltage supply apparatus includes a plurality of integrated circuits (ICs) which each include a first through silicon via (TSV) and a second TSV, are stacked such that the first TSVs are connected and second TSVs are connected, and are mounted on a printed circuit board (PCB), wherein a first PCB line formed on the PCB and supplying a first voltage is connected to a bottom of a first TSV of a bottom IC from among the plurality of ICs, and a second PCB line formed on the PCB and supplying a second voltage is connected to a top of a second TSV of a top IC.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: February 17, 2015
    Assignee: Soongsil University Research Consortium Techno-Park
    Inventors: Chang Kun Park, Ho Yong Hwang
  • Catalysts comprising salan ligands
    Patent number: 8957171
    Abstract: Catalysts comprising salan ligands with carbazole moieties. Also, catalyst systems comprising the catalyst and an activator; methods to prepare the ligands, catalysts and catalyst systems; processes to polymerize olefins using the catalysts and/or catalyst systems; and the olefin polymers prepared according to the processes.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: February 17, 2015
    Assignees: ExxonMobil Chemical Patents Inc., Ramot at Tel-Aviv University Ltd.
    Inventors: Garth R. Giesbrecht, Gregory S. Day, Matthew W. Holtcamp, Moshe Kol, David A. Cano, Eric D. Whetmore, Konstantin Press
  • Low image sticking OLED display
    Patent number: 8957579
    Abstract: Devices and fabrication methods thereof are provided which reduce image sticking and/or improve lifetime and performance of blue emissive devices. Each device may include non-common transport layers between emissive devices, one or more optical capping layers, light and deep blue emissive devices, a mixed host emissive layer, a high T1 transport layer, and/or a stacked blue device in conjunction with single emissive layer red and/or green devices. The provided structures may be used individually, in combination, or as a group in a single device.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: February 17, 2015
    Assignee: Universal Display Corporation
    Inventors: Michael Stuart Weaver, Michael Hack, Julia J. Brown, Mauro Premutico
  • Method and device for maximum power point tracking of photovoltaic module systems
    Patent number: 8957643
    Abstract: A method of maximum power point tracking for a photovoltaic module system is disclosed. The photovoltaic module system may comprise a photovoltaic module array comprising a plurality of identical photovoltaic modules, and the tracking method may comprise: detecting system parameters and environmental parameters of the photovoltaic module array; estimating a first voltage coefficient of one photovoltaic module according to the system parameters and the environmental parameters; estimating a plurality of second voltage coefficients of the photovoltaic module array according to the first voltage coefficient with different shading ratios; estimating a plurality of local maximum power point powers according to corresponding second voltage coefficients; and determining a whole maximum power point by comparing the local maximum power point powers with one another.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: February 17, 2015
    Assignee: National Taiwan University
    Inventors: Joe Air Jiang, Jen Cheng Wang, Yu Li Su, Kun-Chang Kuo, Jyh-Cherng Shieh
  • Constructs binding to phosphatidylserine and their use in disease treatment
    Patent number: 8956616
    Abstract: Disclosed are new phosphatidylserine binding constructs with surprising combinations of properties, and a range of diagnostic and therapeutic conjugates thereof. The new constructs effectively bind phosphatidylserine targets in disease and enhance their destruction, and can also specifically deliver attached imaging or therapeutic agents to the disease site. Also disclosed are methods of using the new construct compositions, therapeutic conjugates and combinations thereof in tumor vasculature targeting, cancer diagnosis and treatment, and for treating viral infections and other diseases.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: February 17, 2015
    Assignees: Board of Regents, The University of Texas System, Peregrine Pharmaceuticals, Inc.
    Inventors: Philip E. Thorpe, Troy A. Luster, Steven W. King
  • Method of inducing antibodies to human immunodeficiency virus involving the administration of MPER peptide-liposome conjugates
    Patent number: 8956627
    Abstract: The present invention relates to a method of inducing the production in a patient of anti-HIV antibodies. The method comprises administering to a patient in need thereof an amount of at least one liposome-peptide conjugate in an amount sufficient to effect that induction. The peptide comprises a membrane external proximal region (MPER) epitope and the liposome comprises lysophosphorylcholine or phosphatidylserine.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: February 17, 2015
    Assignee: Duke University
    Inventors: Barton F. Haynes, S. Munir Alam, Hua-Xin Liao
  • Insect repellant fabrics having nanocapsules with insecticide
    Patent number: 8956634
    Abstract: The present invention relates to method of manufacturing a prytheroid-treated fabric and manufactured products created thereby. Through the development and application of prytheroid nanocapsules to a fabric, the fabric exhibits insecticidal properties, even following successive washings and solar exposure.
    Type: Grant
    Filed: July 2, 2007
    Date of Patent: February 17, 2015
    Assignee: The Hong Kong Polytechnic University
    Inventors: John Haozhong Xin, Fei Bin
  • Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications
    Patent number: 8956658
    Abstract: The presently disclosed subject matter relates to nitric oxide-releasing particles for delivering nitric oxide, and their use in biomedical and pharmaceutical applications.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: February 17, 2015
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Mark H. Schoenfisch, Jae Ho Shin, Nathan Stasko
  • Transparent electrochemical energy storage devices
    Patent number: 8956757
    Abstract: A transparent electrochemical energy storage device includes a pair of electrodes and an electrolyte disposed between the electrodes. Each of the electrodes includes a substrate and a set of electrode materials that are arranged across the substrate in a pattern with a feature dimension no greater than 200 ?m and occupying an areal fraction in the range of 5% to 70%.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: February 17, 2015
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Yuan Yang, Liangbing Hu, Yi Cui, Sangmoo Jeong
  • Proliposomal testosterone formulations
    Patent number: 8957053
    Abstract: Novel testosterone formulations are disclosed where testosterone is incorporated into a phospholipid/cholesterol system to produce a proliposomal powder dispersion. The proliposomal powder dispersions of the invention may be formulated with pharmaceutically acceptable excipients to form pharmaceutical compositions. Enterically coated oral dosage forms are disclosed as are methods of treatment for testosterone replacement therapy.
    Type: Grant
    Filed: January 7, 2014
    Date of Patent: February 17, 2015
    Assignees: Tesorx Pharma, LLC, Western University Health Sciences
    Inventors: Guru V. Betageri, Ramachandran Thirucote, Veeran Gowda Kadajji
  • Cancer treatment targeting non-coding RNA overexpression
    Patent number: 8957042
    Abstract: Provided herein are methods directed to modulating the pro-oncogenic effects of noncoding RNAs (ncRNAs) through their interactions with specificity protein transcription factors (SpTFs). In one aspect, the disclosure provides a method of inhibiting growth of a cell, such as a transformed or cancer cell, characterized by overexpression of at least one specificity protein (Sp)-regulated ncRNA and expression of at least one Sp transcription factor (SpTF), the method comprising contacting the cell with an effective amount of an SpTF agent. In some embodiments, the ncRNA is a long noncoding RNA (lncRNA). In some embodiments, the ncRNA is a microRNA (miR). Also provided are methods of treating a cell proliferative disease, predicting the response of a subject to SpTF agent-based treatment, and monitoring the efficacy of a SpTF agent-based treatment in a subject.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: February 17, 2015
    Assignee: The Texas A&M University System
    Inventors: Stephen Safe, KyoungHyun Kim
  • Use of 5,6-dimethylxanthenone-4-acetic acid as an antiviral agent
    Patent number: 8957108
    Abstract: The invention relates to the areas of therapeutics, pharmaceuticals, drug discovery, and immunotherapy. More specifically, the present invention relates to methods of stimulating the immune system through the administration of flavone acetic acid [FAA] analogs, and in particular, the flavone acetic acid analog, 5,6-dimethylxanthenone-4-acetic acid (DMXAA) so as to comprise an antimicrobial therapeutic agent for the treatment of viral infections of DNA and RNA viruses in humans and non-human animals. The invention is especially suitable for use in a process of treating and preventing infection by, for example, rhinoviruses, enteroviruses, and influenza viruses.
    Type: Grant
    Filed: March 14, 2011
    Date of Patent: February 17, 2015
    Assignee: University of Maryland, Baltimore
    Inventors: Stefanie N. Vogel, Zachary J. Roberts, Jorge Blanco