Abstract: The present disclosure describes operationally simple methods for the low temperature, catalytic activation of carboxylic acids for organic reactions, in particular for direct amidation reactions with amines. The methods involve the use of orthosubstituted arylboromc acids of the formula (I), wherein the groups R1 to R5 are as defined herein. In preferred embodiments R1 is halogen. The arylboromc acids catalyze nucleophilic 1,2-addition reactions, conjugate 1,4-addition reactions, and cycloaddition reactions, including Diels-Alder reactions involving ?,?-unsaturated carboxylic acids.

Abstract: The present invention relates to an oil-pressure type fixed piston sampler for sampling a soil sample for site investigation. The oil-pressure type fixed piston sampler comprises a sampling unit (12) and an oil-pressure controller (14). Here, when the sampling unit (12) inserted into a drilled hole and a movable piston (80) moves downward, a sampling tube (1) moves downward to take a sample. The oil-pressure controller (14) connected with the sampling unit (12) controls oil pressure to cause the movable piston (80) to shift vertically. The sampling unit (12) comprises an upper head (20), a lower head (40), a piston housing (70), a rod block (100), a movable rod (90), a fixed piston (110), a fixed rod (92) and a separation rod (94). Since the sampling tube (1) takes a sample by a piston indentation method, high-quality, undisturbed samples can be obtained.

Abstract: A three dimensional (3-D) light-emitting-diode (LED) stack and method of manufacturing the same, comprising: a substrate; at least a first LED, stacked on said substrate; and at least a second LED, stacked on said first LED, such that energy gap of said first LED is smaller than energy gap of said second LED. In said stack mentioned above, a material of larger energy gap capable of emitting light of shorter wavelength can be penetrated by lights emitted by another material of smaller energy gap capable emitting lights of longer wavelength, such that lights are mixed together and then emitted, and said materials are put into a three dimensional stack arrangement, to form a brand new light emitting device of mixed light, so as to emit lights as required.

Abstract: Provided is alloy for medical use and a medical device that is novel and useful. The alloy for medical use according to, for example, an embodiment of the present invention is mainly composed of three kinds of elements of gold (Au), platinum (Pt), and niobium (Nb). A total content of the three kinds of elements can be no smaller than 99% by weight, in which a platinum content can be no smaller than 5% by weight and no greater than 50% by weight and a niobium content can be no smaller than 3% by weight and no greater than 15% by weight. By adjusting the content ratio of the three elements, for example, it is possible to reduce or prevent artifacts in an MRI. Non-magnetization is also possible.

Abstract: Disclosed are: a ligand for an asymmetric synthesis catalyst; and a process for producing an ?-alkenyl cyclic compound using the ligand. Specifically disclosed are: a ligand for an asymmetric synthesis catalyst, which is represented by any one of formulae (1) to (4) [wherein R1 represents —Cl or —Br; R2 represents —CH3 or —CF3; and R3 represents —CH2—CH?CH2 or —H]; and a process for producing an ?-alkenyl cyclic compound using the ligand.

Abstract: Disclosed is a mobile application search method and system using a human activity knowledge database. The mobile application search system includes a user interface unit that provides an input environment to allow a user to input a user query and displays a mobile application search result related to the user query and a mobile application search engine that receives the user query from the user interface unit and searches for a mobile application related to the user query using an activity knowledge database in which a list of elements involved in achieving a plurality of goals that people desire in daily life is stored. The present invention increases the user's satisfaction by solving a word mismatching problem between a user query and a mobile application and improves mobile application search performance using a human activity knowledge database.

Abstract: Systems and methods selectively stimulate components of the pudendal nerve away from the sacral root to evoke desired physiologic responses in persons who lack the ability to otherwise produce these responses—e.g., maintain continence and/or produce micturition, and/or provide male/female sexuality responses, and/or provide bowel responses. The systems and methods use a multiple electrode array, or individual electrodes, placed on, in, or near the pudendal nerve. The electrode array, or individual electrodes, in association with a pulse generator, provide selective stimulation of individual fascicles within the pudendal nerve, to achieve different physiologic responses.

Abstract: The present invention includes assays and kits for detecting the assembly of an RNA binding protein-RNA complex and for detecting the activity of an RNA binding protein.

Abstract: A method for making a branched carbon nanotube structure includes steps, as follows: providing a substrate and forming a buffer layer on a surface of the substrate; depositing a catalyst layer on the surface of the buffer layer; putting the substrate into a reactive device; and forming the branched carbon nanotubes on the surface of the buffer layer and along the surface of the buffer layer by a chemical vapor deposition method. The material of the catalyst layer is non-wetting with the material of the buffer layer at a temperature that the branched carbon nanotube are formed. A yield of the branched carbon nanotubes in the structure can reach about 50%.

Abstract: Bite blocks providing an instrument lumen 62 for use during transoral medical procedures may be made from a material having a Shore D hardness less than 60 for improved patient comfort. An air way lumen 64 may be provide in side by side arrangement to the instrument lumen 62 for maintaining the patient's airway. The air way 70 may have a concave guiding channel 72 for helping to guide the instruments down the esophagus.

Abstract: Engineered mutant xylose reductases demonstrate higher preference to xylose than arabinose. Amino acid mutations were engineered in to native xylose reductase from Neurospora crassa. Mutant xylose reductases are useful in the production of xylitol and ethanol.

Abstract: The present invention provides a method for adjusting a maximum power of a circuit having a first voltage output and a first power. The method includes the following steps: (a) obtaining a voltage coefficient by measuring the first power of the circuit and calculating an open-circuit voltage of the first voltage output; (b) estimating an estimated power based on the voltage coefficient; and (c) repeating the steps (a) to (b) for a specific number of times, in which the specific number of times is determined based on a variation of the estimated power during a time period.

Abstract: Si—Ge materials are grown on Si(100) with Ge-rich contents (Ge>50 at. %) and precise stoichiometries SiGe, SiGe2, SiGe3 and SiGe4. New hydrides with direct Si—Ge bonds derived from the family of compounds (H3Ge)xSiH4-x (x=1-4) are used to grow uniform, relaxed, and highly planar films with low defect densities at unprecedented low temperatures between about 300-450° C. At about 500-700° C., SiGex quantum dots are grown with narrow size distribution, defect-free microstructures and highly homogeneous elemental content at the atomic level. The method provides for precise control of morphology, composition, structure and strain. The grown materials possess the required characteristics for high frequency electronic and optical applications, and for templates and buffer layers for high mobility Si and Ge channel devices.

Abstract: The subject invention provides at least one nucleic acid sequence encoding an aldouronate-utilization regulon isolated from Paenibacillus sp. strain JDR-2, a bacterium which efficiently utilizes xylan and metabolizes aldouronates (methylglucuronoxylosaccharides). The subject invention also provides a means for providing a coordinately regulated process in which xylan depolymerization and product assimilation are coupled in Paenibacillus sp. strain JDR-2 to provide a favorable system for the conversion of lignocellulosic biomass to biobased products. Additionally, the nucleic acid sequences encoding the aldouronate-utilization regulon can be used to transform other bacteria to form organisms capable of producing a desired product (e.g., ethanol, 1-butanol, acetoin, 2,3-butanediol, 1,3-propanediol, succinate, lactate, acetate, malate or alanine) from lignocellulosic biomass.

Abstract: A method for forming at least a tooth root in a tooth containing a tooth crown, including: forming a culture core containing the tooth and a cell-containing base material, the tooth being wrapped with the cell-containing base material, and culturing the culture core in a medium to form at least the tooth root in the tooth contained therein, wherein the cell-containing base material contains at least one kind of cells selected from periodontal ligament-derived cells, bone marrow-derived cells, dental follicle-derived cells, dental pulp-derived cells and dental papilla-derived cells, and the medium contains a component contained in a conditioned medium of a serum-free-cultured cell line of a human uterocervical squamous carcinoma cell line; an additive containing at least one selected from IL-1?, IL-6, IL-8, IL-9, EGF, IGF-I, GH, PDGF-AB, VEGF, LIF, HGF, FGF-2, FGF-1, BMP-2, BMP-4, M-CSF, dexamethasone, insulin, thyroxine, thyrocalcitonin, ascorbic acid and ?-glycerophosphate; or both of them.

Abstract: Compositions and methods for targeted delivery of therapeutic agents, and particularly for mucosal, oral, nasal, or parenteral delivery of therapeutic agents. The compositions comprise carrier particles containing or encapsulating a therapeutic agent or agents, which have been modified on their surface to contain one or more targeting moieties that enable the enhanced uptake and transport of the therapeutic agent via receptor-mediated processes such as endocytosis or transcytosis.

Abstract: Provided is a technique for X-ray reflection, such as an X-ray reflecting mirror, capable of achieving a high degree of smoothness of a reflecting surface, high focusing (reflecting) performance, stability in a curved surface shape, and a reduction in overall weight. A silicon plate (silicon wafer) is subjected to thermal plastic deformation to form an X-ray reflecting mirror having a reflecting surface with a stable curved surface shape. The silicon wafer can be deformed to any shape by applying a pressure thereto in a hydrogen atmosphere at a high temperature of about 1300° C. The silicon plate may be simultaneously subjected to hydrogen annealing to further reduce roughness of a silicon surface to thereby provide enhanced reflectance.

Abstract: The disclosure relates to a protein composed of a first polypeptide or polypeptide domain having a first specific binding activity for Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) expressed on a T-cell cell surface and a second specific binding activity for Glucose Transporter 2 (GLUT2) or an extracellular ectodomain thereof expressed on a pancreatic ?-cell surface, wherein binding of the first polypeptide or polypeptide domain to CTLA-4 induces a CTLA-4 specific agonist response in the T-cell, and binding of the second polypeptide or polypeptide domain to GLUT2 or an ectodomain thereof does not inhibit GLUT2 glucose transporter function, wherein said agonist response in the T-cell induces a response that reduces immunoreactivity against pancreatic ?-cells.

Abstract: Methods and systems for cryptography use a reconfigurable platform to perform cryptographic functions. Where a reconfigurable platform is use the configuration may be used as a key or secret. The function schema may be maintained as public. The reconfigurable platform may be implemented in a manner to provide desirable families of functions, including reconfigurable functions which are pseudo one-way and pseudo random. An electronic device may include a reconfigurable platform adapted to perform cryptographic functions wherein a configuration of the reconfigurable platform is used as a secret.

Abstract: A diaphragm includes a diaphragm and a voice coil bobbin. The diaphragm includes a membrane and a first reinforcing structure reinforcing the membrane. The voice coil bobbin includes a base and a second reinforcing structure reinforcing the base. The first reinforcing structure and the second reinforcing structure are a carbon nanotube structure. The carbon nanotube structure is disposed on the membrane and the base, or in the membrane and the base.