Patents Assigned to University
  • Rapid custom intra-articular ligament reconstruction guide
    Patent number: 8808301
    Abstract: Custom surgical guides based on the patient's unique anatomy that can be quickly and accurately applied intra-operatively without navigation are disclosed. The device is created using preoperative MRI images and uniquely conforms to the bone in the region of the desired tunnel. The images are filtered and used to generate computerized three dimensional models of the patient's anatomy. The models can be introduced through a portal and applied to the bone denuded of soft tissue.
    Type: Grant
    Filed: August 7, 2009
    Date of Patent: August 19, 2014
    Assignee: University of South Florida
    Inventor: Charles Nofsinger
  • Method and compositions for prevention and treatment of malaria infections
    Patent number: 8809494
    Abstract: Isolated proteins and nucleic acid sequence encoding such protein that interacts with a red blood cell to be invaded by a malaria parasite and link with a component of the actin-myosin based machinery of the malaria parasite are provided. In addition methods for identifying agents which inhibit the function of these proteins as chemotherapeutic and/or immunologic agents for treatment and prevention of malaria infections are provided. Compositions for treatment and prevention of malaria infections and methods for preventing and treating malaria infections are also provided.
    Type: Grant
    Filed: November 17, 2005
    Date of Patent: August 19, 2014
    Assignee: Drexel University
    Inventors: Lawrence W. Bergman, Akhil B. Vaidya
  • Platinum complex, manufacturing method thereof and platinum catalyst constructed thereby
    Patent number: 8809564
    Abstract: A manufacturing method of a platinum complex is mixing chloroplatinic acid and a chelating agent with a solvent, wherein [PtCl6]2? ions of the chloroplatinic acid is reacted with the chelating agent to form a platinum complex Pt[R]2+, wherein the chelating agent(R) is selected from ethylenediamine, 1,10-phenanthroline, 2,2?-Bipyridine, diethylenetriamine, triethylenetetraamine, phenanthroline, or bipyridine. Moreover, a method for producing a platinum catalyst on supports is mixing the chloroplatinic acid, a chelating agent and supports with a solvent to form a platinum complex, which is incorporated onto the supports. Following, a reduction step and a drying step are processed to get the platinum catalyst on the supports.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: August 19, 2014
    Assignee: National Cheng Kung University
    Inventors: Weng-Sing Hwang, Shyh-Jiun Liu, Chia-Hung Huang, Chun-Kai Huang
  • Devices and methods for long-term intracellular access
    Patent number: 8808516
    Abstract: Nanoscale probes for forming stable, non-destructive seals with cell membranes. The probes, systems including these probes, and methods of fabricating and using the probes described herein may be used to sense from, stimulate, modify, or otherwise effect individual cells or groups of cells. In particular, described herein are nanoscale cellular probes that may be used to span the lipid membrane of a cell to provide stable and long lasting access to the internal cellular structures. Thus, the probes described herein may be used as part of a system, method or device that would benefit from stable, non-destructive access across a cell membrane. In some variations the nanoscale probe devices or systems described herein may be used as part of a drug screening procedure.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: August 19, 2014
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Nicholas Alexander Melosh, Piyush Verma, Benjamin David Almquist
  • Detection and measurement of mass change using an electromechanical resonator
    Patent number: 8809065
    Abstract: A change in impedance of a electromechanical resonating sensor is utilized to detect and/or measure a change in mass accumulated on the sensor. The impedance is monitored at a fixed frequency. The fixed frequency may be at or near the resonance frequency of the sensor. In various configurations, the sensor comprises a quartz crystal microbalance sensor or a piezoelectric cantilever sensor.
    Type: Grant
    Filed: May 19, 2010
    Date of Patent: August 19, 2014
    Assignee: Drexel University
    Inventors: Rajakkannu Mutharasan, Sen Xu, Blake N. Johnson, Harsh Sharma, Ramji S. Lakshmanan
  • Method for making Schottky barrier diode
    Patent number: 8809107
    Abstract: A method for making a Schottky barrier diode includes the following steps. A first metal layer, a second metal layer and a carbon nanotube composite material are provided. The carbon nanotube composite material is applied on the first metal layer and the second metal layer to form a semiconductor layer. The carbon nanotube composite material includes an insulated polymer and a number of carbon nanotubes dispersed in the insulated polymer. The semiconductor layer is in Schottky contact with the first metal layer and in ohmic contact with the second metal layer.
    Type: Grant
    Filed: December 26, 2011
    Date of Patent: August 19, 2014
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Chun-Hua Hu, Chang-Hong Liu, Shou-Shan Fan
  • RNA complexes, methods of their production and sensors and analytical methods involving same
    Patent number: 8809512
    Abstract: The invention includes RNA complexes comprising at least three monomeric units of an RNA molecule, each monomeric unit comprising an RNA polymer having first and second helical domains that have respective first and second binding sites, wherein the first binding sites are adapted to binding to one another and are not adapted to bind to the second binding sites, and the second binding sites are adapted to binding to one another and are not adapted to bind to the first binding sites; such that the at least three monomeric units are adapted to self-assemble by forming pairs of cognate interactions and so as to form the RNA complex in a circular closed complex. The invention also includes derivatives of these complexes including aptamers, and analytical methods and devices using same.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: August 19, 2014
    Assignee: Bowling Green State University
    Inventor: Neocles Leontis
  • Solar cell system
    Patent number: 8809675
    Abstract: A solar cell system includes a number of P-N junction cells, a number of inner electrodes, a first collecting electrode, a second collecting electrode and a reflector. The number of the P-N junction cells is M. M is equal to or greater than 2. The M P-N junction cells are arranged from a first P-N junction cell to an Mth P-N junction cell along the straight line. The P-N junction cells are arranged in series along a straight line. The number of the inner electrodes is M?1. At least one inner electrode includes a carbon nanotube array. A photoreceptive surface is parallel to the straight line. A reflector is located on an emitting surface opposite to the photoreceptive surface.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: August 19, 2014
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Yuan-Hao Jin, Qun-Qing Li, Shou-Shan Fan
  • Methods of optically monitoring wound healing
    Patent number: 8812083
    Abstract: Optical changes of tissue during wound healing measured by Near Infrared and Diffuse Reflectance Spectroscopy are shown to correlate with histologic changes. Near Infrared absorption coefficient correlated with blood vessel in-growth over time, while Diffuse Reflectance Spectroscopy (DRS) data correlated with collagen concentration. Changes of optical properties of wound tissue at greater depths are also quantified by Diffuse Photon Density Wave (DPDW) methodology at near infrared wavelengths. The diffusion equation for semi-infinite media is used to calculate the absorption and scattering coefficients based on measurements of phase and amplitude with a frequency domain or time domain device. An increase in the absorption and scattering coefficients and a decrease in blood saturation of the wounds compared to the non wounded sites was observed. The changes correlated with the healing stage of the wound.
    Type: Grant
    Filed: April 21, 2009
    Date of Patent: August 19, 2014
    Assignees: Philadelphia Health & Education Corporation, Drexel University
    Inventors: Elisabeth S. Papazoglou, Leonid Zubkov, Michael T. Neidrauer, Linda Zhu, Kambiz Pourrezaei, Michael S. Weingarten
  • Feedforward control of downstream register errors for electronic roll-to-roll printing system
    Patent number: 8807032
    Abstract: An ultra-precision register control method in a continuous roll-to-roll printing process for manufacturing electronic devices via a feedforward register control logic, which compensates for and eliminates additional register errors attributable to variations in the speed of upstream printing cylinders. When used in combination with a conventional feedback register control logic, the feedforward register control logic accomplishes a register control with ultra-precision in a continuous roll-to-roll printing process, and enables implementation of a continuous roll-to-roll printing process for manufacturing electronic devices, for which a roll-to-roll printing process was formerly unavailable.
    Type: Grant
    Filed: August 19, 2010
    Date of Patent: August 19, 2014
    Assignee: Konkuk University Industrial Cooperation Corp.
    Inventors: Kee-Hyun Shin, Hyun-Kyoo Kang
  • Functionalized inorganic films for ion conduction
    Patent number: 8808807
    Abstract: Novel membranes based on functionalized porous inorganic materials for ion exchange and conduction have been synthesized and characterized. The preparation procedure of these new membranes involves the synthesis of porous inorganic films, into which hydrophilic moieties are incorporated along the interior pore surfaces of the inorganic framework. Ion-conducting species are grafted into the pores via reactions with surface groups of the inorganic framework to allow for ion transport through the pore network.
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: August 19, 2014
    Assignee: The Regents of the University of California
    Inventors: Bradley F. Chmelka, George L. Athens
  • Laser ablation electrospray ionization (LAESI) for atmospheric pressure, in vivo, and imaging mass spectrometry
    Patent number: 8809774
    Abstract: The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation with electrospray ionization (ESI).
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: August 19, 2014
    Assignee: The George Washington University
    Inventors: Akos Vertes, Peter Nemes
  • Designing digital processors using a flexibility metric
    Patent number: 8812285
    Abstract: Techniques, structures, and systems are disclosed for implementing an efficient design of computer hardware using a top-to-bottom approach. In one aspect, a method for designing a processor includes generating an initial architecture for a processor to execute algorithms, simulating execution of the algorithms by the initial architecture to determine a modification to the initial architecture, and creating a processor design based on the modification to the initial architecture. The described method for implementing a hardware design tool provides a push-button transition from high level specification for algorithms to hardware description language.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: August 19, 2014
    Assignee: The Regents of the University of California
    Inventors: Ali Umut Irturk, Ryan Charles Kastner
  • Integrated low-noise sensing circuit with efficient bias stabilization
    Patent number: 8810262
    Abstract: An integrated low-noise sensing circuit with efficient bias stabilization in accordance with the present invention comprises a first capacitance sensing element, a second capacitance sensing element, a sub-threshold transistor and an amplifier circuit wherein the first stage is an input transistor. The second capacitance sensing element is connected to the first capacitance sensing element. The sub-threshold transistor comprises a body, a gate, a source, a drain, a source-body junction diode and a bulk. The gate forms on top of the body. The source forms on the body and is connected to the first capacitance sensing element and the second capacitance sensing element. The drain forms on the body and is connected to the gate and the amplifier output terminal. The source-body junction diode comprises an anode and a cathode. The anode is connected to the ground.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: August 19, 2014
    Assignee: National Tsing Hua University
    Inventors: Yung-Jane Hsu, Siew-Seong Tan
  • Receiver, signal demodulation module and demodulation method thereof
    Patent number: 8811541
    Abstract: A signal demodulation module is disclosed. The signal demodulation module includes an injection-locked oscillator, an envelope detector and a data slicer. The injection-locked oscillator has a central oscillating frequency equal to a frequency of a digital modulation signal received, and outputs a phase-locked oscillating signal which is in phase to the digital modulation signal. When input phase of the digital modulation signal changes, output phase of the injection-locked oscillator changes synchronously. The envelope detector is used for detecting an envelope line of the phase-locked oscillating signal and outputting an envelope signal accordingly. The data slicer is used for receiving the envelop signal and outputting a first digital signal according to a reference voltage and the envelop signal.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: August 19, 2014
    Assignee: National Taiwan University
    Inventors: Yi-Lin Tsai, Jian-You Chen, Bang-Cyuan Wang, Tsung-Hsien Lin
  • Titanium-based thermal ground plane
    Patent number: 8807203
    Abstract: Titanium-based thermal ground planes are described. A thermal ground plane in accordance with the present invention comprises a titanium substrate comprising a plurality of pillars, wherein the plurality of Ti pillars can be optionally oxidized to form nanostructured titania coated pillars, and a vapor cavity, in communication with the plurality of titanium pillars, for transporting thermal energy from one region of the thermal ground plane to another region of the thermal ground plane.
    Type: Grant
    Filed: July 21, 2009
    Date of Patent: August 19, 2014
    Assignee: The Regents of the University of California
    Inventors: Noel C. MacDonald, Carl D. Meinhart, Changsong Ding, Payam Bozorgi, Gaurav Soni, Brian D. Piorek
  • System and method for alignment of nanoparticles on substrate
    Patent number: 8808558
    Abstract: The invention provides a system and method for alignment of nanoparticles on a substrate. The system includes: a substrate; a plurality of polypeptide templates formed on the substrate; and a plurality of nanoparticles formed on the polypeptide templates. The method includes: providing a substrate; forming a plurality of polypeptide templates on the substrate; and forming a plurality of nanoparticles on the polypeptide templates.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: August 19, 2014
    Assignee: National Sun Yat-Sen University
    Inventor: Shu-Chen Hsieh
  • Devices, systems, and methods for dispersive energy imaging
    Patent number: 8809771
    Abstract: Devices, systems, and methods for dispersive energy imaging are disclosed. The full three-dimensional velocity distribution function of a flowing particle stream may be measured and properties of the particle stream characterized. In some devices, an aperture system controls the entry of a stream of particles into the sensor where an electrostatic deflector separates the stream of particles into different species, and a detector system senses the separated species.
    Type: Grant
    Filed: May 13, 2011
    Date of Patent: August 19, 2014
    Assignee: Utah State University Research Foundation
    Inventor: Erik Syrstad
  • Synthetic methods and intermediates for the preparation of xenicanes
    Patent number: 8809558
    Abstract: The invention provides novel synthetic intermediates and synthetic methods that are useful for preparing compounds of the xenicane family. Certain compounds of the invention may also possess anti-cancer properties.
    Type: Grant
    Filed: August 23, 2011
    Date of Patent: August 19, 2014
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Lawrence J. Williams, Michael Drahl, Madhuri Manpadi
  • Thermoacoustic device
    Patent number: 8811633
    Abstract: A thermoacoustic device includes a carbon nanotube composite structure, a sound wave generator and a signal input device. The carbon nanotube composite structure includes a carbon nanotube structure and a matrix. The matrix is located on a surface of the carbon nanotube structure. The sound wave generator is located on a surface of the carbon nanotube composite structure and insulated from the carbon nanotube structure via the coating layer. The sound wave generator includes a carbon film. The signal input device is configured to input signals to the sound wave generator.
    Type: Grant
    Filed: December 26, 2011
    Date of Patent: August 19, 2014
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Kai-Li Jiang, Xiao-Yang Lin, Lin Xiao, Shou-Shan Fan