Abstract: The invention relates to an amphiphilic polymer comprising at least 75% of amphiphilic monomers of formula (I), the average molar mass of the polymer being between 800 and 100 000, and also water-soluble complexes between the polymer according to the invention and a hydrophobic or amphiphilic compound, in particular a membrane protein, a concentrated aqueous solution of one or more such complex(es), a product comprising one or more such complex(es) attached to a substrate by means of the polymer according to the invention, and various uses of these products.

Abstract: The invention relates to methods of medically treating mammals with Eustachian tube dysfunctions, such as Ménière's disease, vertigo, Otitis Media (including Otitis Media with Effusion (OME), Acute Otitis Media (AOM) and Aerotitis Media (AM)) as well as other disorders which are characterized by ET dysfunction.

Abstract: The present invention relates to materials, methods and apparatuses for performing imprint lithography using amorphous metallic materials. The amorphous metallic materials can be employed as imprint media and thermoplastic forming processes are applied during the pattern transfer procedure to produce micron scale and nanoscale patterns in the amorphous metallic layer. The pattern transfer is in the form of direct mask embossing or through a serial nano-indentation process. A rewriting process is also disclosed, which involves an erasing mechanism that is accomplished by means of a second thermoplastic forming process. The amorphous metallic materials may also be used directly as an embossing mold in imprint lithography to allow high volume imprint nano-manufacturing. This invention also comprises of a method of smoothening surfaces under the action of the surface tension alone.

Abstract: Antioxidant polymeric compounds are provided that comprise a plurality of monomeric portions, where each monomeric portion includes an antioxidant molecule interposed between at least two acrylate molecules, and where at least one acrylate molecule of each monomeric portion is linked by a diamine molecule to an acrylate molecule of an adjacent monomeric portion to thereby form the polymer. Methods of synthesizing polymeric compounds and methods of using the antioxidant polymeric compounds to reduce oxidative stress are also provided.

Abstract: The present invention provides analogs and derivatives of thalidomide which inhibit cancer and angiogenesis. The present invention further provides compounds which disrupt microtubule polymerization. The present further provides methods of treating cancers comprising mutant p53.

Abstract: The present invention relates to a diastereomeric mixture of Silacycle Compounds and methods for using the diastereomeric mixture of Silacycle Compounds for stereoselective synthesis.

Abstract: An approach for defending radio frequency identification (RFID) tags and other contactless cards against ghost-and-leech (a.k.a. proxying, relay, or man-in-the-middle) attacks incorporates gesture recognition techniques directly implemented with the RFID tags or contactless cards. These tags or cards will only engage in wireless communications when they internally detect “secret handshakes.” A secret handshake recognition system is implemented on a passive WISP RFID tag having a built-in accelerometer. This approach is backward compatible with existing deployments of RFID tag and contactless card readers and is also designed to minimize the changes to the existing usage model of certain classes of RFID and contactless cards, such as access cards that are kept in a wallet or purse, by enabling execution of secret handshakes without removing the card. This novel approach can also improve the security and privacy properties in other uses of RFID tags, e.g., contactless payment cards.

Abstract: The present invention relates to an environmental load assessment system, which is capable of efficiently and simply assessing an environmental load of a building in all stages (e.g., a planning stage, a design stage, a construction stage, and a use stage after construction) in doing executing a business by subdividing an assessment process, such as simple assessment in the design stage, detailed assessment in the start stage, and site assessment in the construction stage according to the progress of a construction project.

Abstract: Multiple designs, systems, methods and processes for controlling a system or plant using an extended active disturbance rejection control (ADRC) based controller are presented. The extended ADRC controller accepts sensor information from the plant. The sensor information is used in conjunction with an extended state observer in combination with a predictor that estimates and predicts the current state of the plant and a co-joined estimate of the system disturbances and system dynamics. The extended state observer estimates and predictions are used in conjunction with a control law that generates an input to the system based in part on the extended state observer estimates and predictions as well as a desired trajectory for the plant to follow.

Abstract: An actuator is provided whose expansion in the radial direction can be efficiently translated into longitudinal movement when its length is contracted and extended by injecting a fluid into the tubular body. The fluid injection type actuator includes an actuator body, which is an expansion and contraction section of the actuator. The actuator body is constructed of a cylindrical rubber tube and annular fiber groups inserted and extending longitudinally therein. The annular fiber groups are each a group of fibers, such as glass roving fibers having a diameter of about 10 ?m, arranged in an annular array along the circumference of the rubber tube. The arrangement allows the rubber tube to be restrained over the entirety of the actuator body longitudinally when it is expanded radially.

Abstract: A generic structure for the peptides of the present invention includes A-X-B-C, where C is a cargo moiety, the B portion includes basic amino acids, X is a cleavable linker sequence, and the A portion includes acidic amino acids. The intact structure is not significantly taken up by cells; however, upon extracellular cleavage of X, the B-C portion is taken up, delivering the cargo to targeted cells. Cargo may be, for example, a contrast agent for diagnostic imaging, a chemotherapeutic drug, or a radiation-sensitizer for therapy. Cleavage of X allows separation of A from B, unmasking the normal ability of the basic amino acids in B to drag cargo C into cells near the cleavage event. X is cleaved extracellularly, preferably under physiological conditions. D-amino acids are preferred for the A and B portions, to minimize immunogenicity and nonspecific cleavage by background peptidases or proteases.

Abstract: A method for making a thermal interface material includes following steps. A substrate having a plurality of CNT arrays arranged thereon and a number of first interspaces defined between the CNT arrays is provided. A container is provided and the substrate with the CNT arrays is disposed into the container. A number of low melting point metallic nanoparticles is provided and filled in the first interspaces. The low melting point metallic nanoparticles in the container is heated into a liquid state, and the low melting point metal nanoparticles in liquid state is combined with the CNT arrays to form a composite material on the substrate. The composite material is peeled off from the substrate, and a thermal interface material is obtained.

Abstract: An apparatus for retaining a photovoltaic panel on a rooftop includes a vessel having a first side, second side, front, bottom, and top panels, wherein the panels are attached to define a void within the vessel. A fill port is disposed on the vessel. A first hole is adapted to receive a screw on the top panel, wherein the first hole is aligned with a second hole disposed on the bottom panel, wherein the first and second holes are adapted to be aligned with a third hole on a first mounting cross arm. The top panel is inclined at an angle relative to the bottom panel.

Abstract: A system for analyzing and detecting early stage damage to the retina related to glaucoma. The reflectance of different wavelengths of light by the retinal nerve fiber layer are compared. Changes in relative reflectance values indicate damage to the retinal nerve fibers and indicate early glaucomatous optical neuropathy.

Abstract: Disclosed herein are methods and devices for delivering gas to a subject and obtaining plethysmograph readings from a subject. Specifically disclosed herein are masks and helmets which comprise one or more pulse oximeter probes associated therewith. The masks and helmets may be used in particular contexts, including, but not limited to, emergency responder personnel, pilots or subjects of medical attention.

Abstract: A system and method for use in NOTES is provided for reducing surgical invasiveness. An insertion body that is connected by an anvil assembly and joined to a thin wire guide or electric guide wire, is inserted via a natural orifice into a hollow organ so as to incise and remove a diseased or defective site from the hollow organ by using a pair of or front-end/rear-end linear cutters of a linear cutting/stapling device or linear stapler, after which the two cut ends of the tract are anastomosed and recovered by a circular anastomosis surgical stapler that is provided with the system.

Abstract: The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described.

Abstract: A method and apparatus for generating an elemental image by an integral image technique are provided. The method includes normalizing coordinates of dots in a frustum formed in perspective projection by mapping the dots in the frustum into a cube; reversing a grade of depth of the cube viewed from a particular viewpoint; and generating a two-dimensional (2D) elemental image necessary for three-dimensional (3D) display from dots in the cube whose grade of depth is reversed.

Abstract: A radiation pattern insulator and an antennae system thereof are proposed. The radiation pattern insulator includes a dielectric substrate and a plurality of radiation pattern insulation elements. The dielectric substrate allocated between a plurality of antennae includes a top surface and a bottom surface, and a normal direction of the dielectric substrate is substantially perpendicular to propagation directions of electromagnetic waves radiated from the antennae. In addition, the radiation pattern insulation elements are allocated on the top surface or the bottom surface of the dielectric substrate, or alternatively, all allocated on the top surface and the bottom surface.

Abstract: Described are methods of determining if a subject has a genetic predisposition to developing prostate cancer (PCa).