Abstract: A method for improving tetracycline-resistance of A. baumannii, by providing a ginger compound combined with tetracycline to against A. baumannii infection, wherein the ginger compound comprises [6]-dehydrogingerdione, [6]-shogaol and [6]-gingerol or [10]-gingerol, [6]-shogaol and [6]-gingerol.

Abstract: Techniques for enhanced isotachophoresis assays using additives with spatial gradients include forming a concentration gradient of an additive along a channel from an input port to an output port. The channel is used for isotachophoresis with ions of a leading electrolyte having a first mobility greater than a mobility of an analyte, and ions of a trailing electrolyte having a second mobility less than the mobility of the analyte. The additive is different from both the leading electrolyte and the trailing electrolyte; and the additive has a third mobility that assures the analyte will encounter the additive. The method further comprises introducing a mixture of the trailing electrolyte and a sample including the analyte. The method further comprises applying an electric field to the channel; and, measuring the analyte.

Abstract: Myeloid differentiating agents can be used in the treatment of myeloid proliferative disorders.

Abstract: A method for manufacturing a compound refractive lens for focusing X-rays in two dimensions. The method includes the following steps: 1) manufacturing a mother lens; 2) manufacturing a daughter lens; and 3) assembling the mother lens and the daughter lens. The assembly of the mother lens and the daughter lens includes: aligning square embedded lens bodies of the daughter lens with square holes of the mother lens, respectively, for allowing the first parabola-shaped holes on the mother lens and the second parabola-shaped holes on the daughter lens to form an orthogonal structure; and inserting and pressing the square embedded lens bodies into the corresponding square holes, respectively. The method of the invention has advantages of high-precision for manufacturing and calibration of optical axis, and meanwhile the compound refractive lens manufactured based the method has high X-rays focusing efficiency.

Abstract: The present invention is directed to a method of determining vein patterns from a colour image for personal identification, the method comprising forming a counterpart of the colour image by applying a functional relationship obtained from optimization on the colour image, wherein the counterpart of the colour image comprises the vein patterns. An apparatus for determining vein patterns from a colour image is also disclosed.

Abstract: The invention relates to genetically modified agricultural plants with increased oil content in vegetative tissues, as well as to expression systems, plant cells, seeds and vegetative tissues related thereto.

Abstract: The present application provides fully human antibodies against N-Cadherin for therapeutic and diagnostic methods in cancer.

Abstract: In some embodiments, the present disclosure pertains to methods of forming single-crystal graphenes by: (1) cleaning a surface of a catalyst; (2) annealing the surface of the catalyst; (3) applying a carbon source to the surface of the catalyst; and (4) growing single-crystal graphene on the surface of the catalyst from the carbon source. Further embodiments of the present disclosure also include a step of separating the formed single-crystal graphene from the surface of the catalyst. In some embodiments, the methods of the present disclosure also include a step of transferring the formed single-crystal graphene to a substrate. Additional embodiments of the present disclosure also include a step of growing stacks of single crystals of graphene.

Abstract: An optoelectronic device as well as its methods of use and manufacture are disclosed. In one embodiment, the optoelectronic device includes a first optoelectronic material that is inhomogeneously strained. A first charge carrier collector and a second charge carrier collector are each in electrical communication with the first optoelectronic material and are adapted to collect charge carriers from the first optoelectronic material. In another embodiment, a method of photocatalyzing a reaction includes using a strained optoelectronic material.

Abstract: The present invention relates to the field of pancreatic progenitor cells. More specifically, the present invention provides methods for isolating self-renewing centroacinar and terminal ductal progenitors from adult human pancreas. In a specific embodiment, the method comprises the steps of (a) providing a population of pancreatic cells; and (b) selecting for high expression of CD133, EpCAM, and CD44 on the pancreatic cells to isolate self-renewing centroacinar and terminal ductal progenitors.

Abstract: Certain embodiments are directed to methods of identifying dementia in subjects comprising, measuring serum levels of one or more of interferon gamma, IL-10, IL-12p40, IL-13, alpha 2 macroglobulin, beta 2 microglobulin, pancreatic polypeptide, prolactin, stem cell factor, thrombopoietin, and Von Willebrand Factor and identifying a subject as having dementia if the levels of the biomarkers is increased.

Abstract: The present invention relates to identification of a human gene, Complement Factor H (CFH), associated with the occurrence for developing age related macular degeneration (AMD), which is useful for identifying or aiding in identifying individuals at risk for developing AMD, as well as for diagnosing or aiding in the diagnosis of AMD.

Abstract: This disclosure relates to methods of using nitrite to detoxify stroma-free hemoglobin based blood substitutes. In particular, methods are described for using a blood substitute comprised of about equimolar amounts of nitrite and hemoglobin (e.g., nitrite-metHb) to treat, prevent, or ameliorate diseases of the blood in a subject, or as a blood replacement in a subject.

Abstract: According to example embodiments of the invention, a microscale testing stage comprises a frame having first and second opposing ends and first and second side beams, at least one deformable force sensor beam, a first longitudinal beam having a free end, a second longitudinal beam having a facing free end, a support structure, and a pair of slots disposed at each of the free ends. In certain embodiments, a layer of a conductive material defines first and second conductive paths and an open circuit that can be closed by the specimen across the gap. In other embodiments, the stage is formed of a high melting temperature material.

Abstract: This invention provides a device for checking the performance of an image-guided radiation therapy (IGRT) apparatus. The device (referred to here as a phantom) has a central body with detectable markers, rotatably suspended on a ball joint so that the pitch, roll, and yaw may be adjusted. The body is secured against a base plate, which in turn may be positioned laterally, longitudinally, and vertically within the patient treatment area. Thus, the phantom can be adjusted through six degrees of freedom so as to simulate patient positioning. To perform quality control, the phantom is secured at a predetermined offset, and the position is detected by the IGRT apparatus. The robotic couch is then allowed to compensate, a second measurement is made. The measured values are compared with the predetermined offset to assess both the accuracy in detecting the position of the phantom, and the accuracy of the mechanical correction.

Abstract: In one aspect, the invention relates to compounds having a general structure: and methods of using same to modulate calcium release. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: Provided according to embodiments of the invention are novel tertiary alkyl thiol compounds and novel tertiary alkyl nitrosothiol compounds. Further provided according to embodiments of the invention are methods of forming a nitric oxide (NO)-releasing xerogel coating that include (a) co-condensing a sol precursor solution comprising at least one backbone alkoxysilane and at least one tertiary thiol alkoxysilane in a solvent to form a sol; (b) coating a substrate with the sol; (c) optionally, drying the sol to form the xerogel coating; and (d) contacting the xerogel coating with a nitrosating agent. Methods of using xerogel coatings are also included.

Abstract: Described herein are methods of determining an HCC subtype in a subject which includes a) obtaining a sample from the subject, b) assaying the sample to detect the expression of 1 or more biomarkers, and c) correlating the expression of the biomarkers with an HCC subtype in a subject. Also described are methods of detecting HCC stem cells in a sample, and methods and compositions for treating subjects with HCC that take advantage of the biomarkers associated with HCC stem cells.

Abstract: A hardware-in-the-loop (HIL) electrical grid simulation system and method that combines a reactive divider with a variable frequency converter to better mimic and control expected and unexpected parameters in an electrical grid. The invention provides grid simulation in a manner to allow improved testing of variable power generators, such as wind turbines, and their operation once interconnected with an electrical grid in multiple countries. The system further comprises an improved variable fault reactance (reactive divider) capable of providing a variable fault reactance power output to control a voltage profile, therein creating an arbitrary recovery voltage. The system further comprises an improved isolation transformer designed to isolate zero-sequence current from either a primary or secondary winding in a transformer or pass the zero-sequence current from a primary to a secondary winding.

Abstract: The invention described in the application relates to a panel of gene expression markers for node-negative, ER-positive, HER2-negative breast cancer patients. The invention thus provides methods and compositions, e.g., kits and/or microarrays, for evaluating gene expression levels of the markers and methods of using such gene expression levels to evaluate the likelihood of relapse of a node-negative, ER-positive, HER2-negative breast cancer patient. Such information can be used in determining treatment options for patients.