Patents Assigned to University
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Publication number: 20120156280Abstract: Myeloid derived suppressor cell (MDSC) inhibitory agents and vaccine and/or adjuvant enhancers are provided. Improved vaccine treatment regimens employing these agents are also provided. Cancer vaccines and methods for inhibiting tumor growth and cancer metastases are also presented. The myeloid derived suppressor cell (MDSC) inhibiting agents are described as bisphosphonates (such as liposomal clodronate) and CCR2 inhibitors and/or CCR2 antagonists. Methods for enhancing antibody titer levels in response to an antigen of interest are also provided.Type: ApplicationFiled: June 22, 2011Publication date: June 21, 2012Applicant: Colorado State University Research FoundationInventors: Steven W. Dow, Angela J. Henderson, Leah Mitchell
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Publication number: 20120154751Abstract: In one example of the invention a patient display is provided on which a fixation graphic or video is shown in substantially the centre of the display, and then target graphics or video are shown at different positions on the display about the centre. A test subject is positioned in front of the patient display a known distance therefrom, and a camera captures an image of the test subject's eyes, to allow gaze direction determination to be performed. The captured images are displayed to a clinician user by a controlling test application, the clinician making a determination based on the images as to whether the test subject saw a target graphic or video when it was displayed. The clinician user then makes an appropriate input into the controlling test application, which also logs the position at which the target image was displayed.Type: ApplicationFiled: August 24, 2010Publication date: June 21, 2012Applicants: University of York, Cambridge Enterprise LimitedInventors: Adar Pelah, Allen Louise Elizabeth, Slater Michael Edward, Jackson Andrew Robert
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Publication number: 20120155735Abstract: A method of analyzing a stream of imaging data is disclosed. The method comprises: for each picture-element of the data, associating a vector of features indicative of temporal intensity variation relative to baseline intensity, thereby providing a plurality of vectors. The method further comprises clustering the picture-elements according to the vectors, thereby providing a plurality of clusters, and identifying different compartments in the vasculature based on the clusters.Type: ApplicationFiled: September 1, 2009Publication date: June 21, 2012Applicants: Mor Research Applications Ltd, Ben Gurion University Of The Negev Research and Development AuthorityInventors: Alon Friedman, Yoash Chassidim, Ofer Psager, Ilan Shelef
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Publication number: 20120156180Abstract: Provided are compositions and methods for the treatment of Krabbe and other neurodegenerative diseases, including storage diseases such as GM1 gangliosidosis, Niemann-Pick disease, Tay-Sachs disease, Sandhoff disease, metachromatic leukodystrophy, Canavan disease, Pelizaeus-Merzbacher disease, and storage conditions facilitated by aging of lysosomal functions, which are associated with psychosine (and/or other storage material)-mediated axonal degeneration.Type: ApplicationFiled: August 10, 2010Publication date: June 21, 2012Applicant: The Board of Trustees of the University of IllinoisInventor: Ernesto Bongarzone
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Publication number: 20120156731Abstract: Disclosed are methods and materials for assembling long polynucleotides from synthetic oligonucleotides. The use of synthetic oligonucleotides permits non-natural design of sequences. The oligonucleotides used for construction may be relatively short, according to practicalities of nucleotide synthesis. They are assembled using a ligase which is operative over a range of temperatures, i.e., is thermostable. The method and oligonucleotides are designed such that the melting temperature of the strands to be hybridized is set at a number of selected specific temperatures for each group of oligonucleotides to be hybridized and ligated. Hybridization and ligation take place at or near the melting temperature, so that each succeeding ligation is governed by a temperature that will prevent hybridization if any mismatches are present.Type: ApplicationFiled: March 20, 2008Publication date: June 21, 2012Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Yanyi Huang, James Berger, Stephen Quake
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Publication number: 20120157700Abstract: The invention features methods for the preparation of naturally occurring trihydroxy polyunsaturated eicosanoids and their structural analogs. The invention further provides new derivatives and analogs of trihydroxy polyunsaturated eicosanoids that can be prepared according to these methods. The invention also provides compositions and methods using trihydroxy polyunsaturated eicosanoid derivatives for the prevention, amelioration and treatment of a variety of diseases or conditions associated with inflammation or inflammatory response, autoimmune diseases, rheumatoid arthritis, cardiovascular diseases, or abnormal cell proliferation or cancer.Type: ApplicationFiled: February 28, 2012Publication date: June 21, 2012Applicant: University of Southern CaliforniaInventor: Nicos A. Petasis
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Publication number: 20120158221Abstract: Emergency aircraft landing systems and methods are described. In one aspect, an emergency landing apparatus includes a support structure for a fuselage and wings of an aircraft and a control system. The control system includes a processor and a memory containing computer program instructions executable by the processor. Execution of the computer program instructions causes an interface on the aircraft to exchange information between an aircraft guidance and control system on the aircraft and the control system. The computer program instructions further synchronize the speed and position of the emergency aircraft landing apparatus on a runway with the speed and flight path of the aircraft.Type: ApplicationFiled: December 20, 2010Publication date: June 21, 2012Applicant: King Saud UniversityInventor: Abdullah Abdulaziz A. AL Fadhli
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Publication number: 20120153514Abstract: Condensable vapors such as carbon dioxide are separated from light gases in a process stream. The systems and methods employ a direct exchange heat exchanger to desublimate the condensable vapors from the process stream. The condensable vapors are condensed by directly contacting a heat exchange liquid in the direct contact heat exchanger while the uncondensed light gases from the process stream form a separated light-gas stream. The separated light-gas stream can be used in a recuperative heat exchanger to cool the process stream.Type: ApplicationFiled: November 21, 2011Publication date: June 21, 2012Applicant: Brigham Young UniversityInventors: Larry L. Baxter, Christopher S. Bence
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Publication number: 20120156300Abstract: Compositions containing a carrier and microbubbles encapsulating one or more gases, preferably oxygen, and methods for making and using the compositions are described herein. The microbubbles contain a lipid envelope. The compositions may be administered to a patient to quickly deliver large amounts of oxygen to the patient's blood supply or directly to a tissue in need of oxygen. The compositions may be administered via injection or as a continuous infusion. The compositions contain a concentrated microbubble suspension, where the suspension contains at least 40 mL oxygen/dL suspension. The microbubbles are preferably less than 20 microns in diameter, more preferably less than 15 microns in diameter. The microbubbles described herein may be administered to a patient in an effective amount to increase in oxygen concentration in the patient's blood, and/or one or more tissues or organs.Type: ApplicationFiled: February 22, 2012Publication date: June 21, 2012Applicants: The Trustees of Columbia UniversityInventors: John Kheir, Mark Andrew Borden, Francis X. McGowan
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Publication number: 20120151931Abstract: An engine includes: (1) a housing defining a combustion chamber; (2) a set of injection mechanisms connected to the housing and configured to introduce a fuel and nanoparticles into the combustion chamber; and (3) an optical ignition system connected to the housing and configured to irradiate the nanoparticles to ignite the fuel.Type: ApplicationFiled: December 14, 2011Publication date: June 21, 2012Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Xiaolin Zheng, Yuma Ohkura
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Publication number: 20120159604Abstract: An embodiment of the present invention includes a system for communicating digital data from a preferably small battery powered device (e.g., key-chain or pocket-sized form-factor) to a personal electronic device (e.g., a smartphone such as an iPhone or a Nexus One). The communication mechanism of the present invention can be used as second factor authentication. The present invention can also be used as a key for accessing physical locations such as building. Alternatively, the present invention can be used as a manner for transmitting digital data to a personal electronic device such as a smart phone.Type: ApplicationFiled: August 11, 2011Publication date: June 21, 2012Applicant: The Board of Trustees of the Leland Stanford, Junior, UniversityInventors: Hristo Bojinov, Dan Boneh
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Publication number: 20120152229Abstract: A range hood capable of resisting draft is provided above a counter on the top of which an air-generation device is located. The range hood comprises an air-extraction hood that has a bottom provided with an elongate air-extraction slot for drawing air upwards. Besides, an air blow groove is provided in front of the elongate air-extraction slot for blowing air downwards. A long left upright plate and a long right upright plate are respectively provided below the left and right lateral surfaces of the air-extraction hood. Thereby, when the elongate air-extraction slot draws in air, an oblique airflow is formed. Besides, the long left and right upright plates are able to hinder the draft coming from lateral sides, so as to protect the oblique airflow structure. Consequently, an intact upwards-flowing airflow is formed to exhaust soot and harmful gases.Type: ApplicationFiled: June 1, 2011Publication date: June 21, 2012Applicant: National Taiwan University of Science and TechnologyInventor: Rong Fung Huang
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Publication number: 20120156792Abstract: The invention provides improvements in reagents for use in electron transfer dissociation ionization techniques for use in mass spectrometry, particularly for sequencing peptides and proteins using mass spectrometric techniques involving electro-spray ionization and MS/MS characterization of fragment ions. The novel reagents used in the inventive methods allow for more effective determination of protein sequences, especially of long peptides or post-translationally modified protein fragments. Use of the polycyclic aromatic hydrocarbons azulene, homoazulene, and acenaphthylene, and homodimers and heterodimers thereof, are described.Type: ApplicationFiled: September 2, 2010Publication date: June 21, 2012Applicant: University of Virginia Patent FoundationInventors: John E.P. Syka, Philip D. Compton, Donald F. Hunt
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Publication number: 20120157381Abstract: The invention features compositions comprising agents having cardiac protective activity isolated from epicardial progenitor cells and derivatives thereof, and methods for the use of such compositions.Type: ApplicationFiled: August 29, 2011Publication date: June 21, 2012Applicant: The University of Vermont and State Agriculture CollegeInventor: Jeffrey Spees
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Publication number: 20120154313Abstract: Described herein are finger registration systems and methods for use with a multi-touch device that can facilitate in place execution of commands or operations, thereby reducing focus switching and minimizing hand movement. The finger registration methods are simple and robust, using only contact points on the touch-based device, without requiring additional hardware. Direct mapping of operations to gestures involving individual fingers or combination of fingers (e.g., finger chords), provides a new and rich set of direct manipulation without focus switching for selecting commands/operations.Type: ApplicationFiled: December 16, 2011Publication date: June 21, 2012Applicant: The Hong Kong University of Science and TechnologyInventors: Kin Chung AU, Chiew-Lan TAI
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Publication number: 20120153685Abstract: A sunroof mounting device is provided, which includes guide rails of which the entire width is reduced by a pair of first and second guiders arranged up and down such that a moving-connecting portion connected to a sunroof is vertically combined in an open space from a side, such that the space opened by the sunroof is not covered by guide rails and improved open feel.Type: ApplicationFiled: December 19, 2011Publication date: June 21, 2012Applicants: Kookmin University Industry Academy Cooperation Foundation, DH HOLDINGS CO., LTD.Inventors: Seung-Jin HEO, Jay-Il JEONG, Il-Hwan KIM, In-Sik HWANG
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Patent number: 8202689Abstract: The invention relates to processes and devices for the controlled fabrication of nanostructures from starting components that have high fidelity recognition properties and multiple binding groups. In one embodiment, the invention relates to the formation of nanostructures using controlled sequential addition of nanocomponents at regular intervials via sequential formation of binding pairs or other chemical binding reactions.Type: GrantFiled: May 11, 2006Date of Patent: June 19, 2012Assignee: The Regents of the University of CaliforniaInventors: Michael Heller, Benjamin Sullivan, Dietrich Dehlinger
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Patent number: 8204114Abstract: A block intra prediction direction detection algorithm comprises acts of dividing a block, finding directions from edge assent rules, determining a main edge of the block, selecting prediction modes from the main edge, choosing base prediction modes and using all unique selected and base prediction modes in intra prediction. The algorithms comprise a 4×4 block intra prediction direction detection algorithm, a 16×16 luminance block intra prediction direction detection algorithm and an 8×8 chrominance block intra prediction direction detection algorithm.Type: GrantFiled: July 3, 2008Date of Patent: June 19, 2012Assignee: National Cheng-Kung UniversityInventors: Jhing-Fa Wang, Wei-Guang Lin, An-Chao Tsai
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Patent number: 8202844Abstract: The present invention provides novel chemical compounds, and methods for their use. In particular, the present invention provides indole derivatives (e.g. as shown in Formula (I)) and related compounds and methods of using indole derivatives and related compounds as therapeutic agents to treat a number of conditions, including those associated with viral infection and cardiovascular diseases.Type: GrantFiled: March 31, 2011Date of Patent: June 19, 2012Assignee: The Regents of the University of MichiganInventors: Leroy B. Townsend, John C. Drach
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Patent number: 8204224Abstract: The present invention provides systems and methods for securing communications in a wireless network by utilizing the inherent randomness of propagation errors to enable legitimate users to dynamically create a shared symmetric secret key. In one embodiment, the invention provides a system with two computers each having a wireless network adapter. The sending node encodes the frames, transmits the frames, determines if the frames were correctly received, retransmits the frames if they were not correctly received, stores the frames that were not retransmitted, and uses the stored frames to generate a secret key. The receiving node receives the encoded frames, determines if the frames were retransmitted, stores at least one of the frames that was not retransmitted, and uses the stored frames to generate the same secret key as the receiving node.Type: GrantFiled: November 24, 2008Date of Patent: June 19, 2012Assignee: University of MassachusettsInventors: Sheng Xiao, Weibo Gong
