Abstract: A method for producing carbon nanotubes uses a polymer as a raw material to undergo in situ thermal decomposition. The method includes steps of mixing the polymer and metallic catalyst through a multiple heating stage process of in-situ thermal decomposition to carbonize the polymer and release carbon elements to produce carbon nanotubes. Advantages of the present invention include easy to prepare, low temperature in manipulation, low production cost, and high safety.

Abstract: Monoclonal antibodies have been generated that bind to human sialoadhesion factor-2. These antibodies are useful as diagnostic and therapeutic reagents.

Abstract: The invention provides compounds of Formula (I): wherein R1 and R2 have any of the values or specific values defined herein, as well as compositions comprising such compounds and therapeutic methods comprising the administration of such compounds.

Abstract: The present invention provides methods and pharmaceutical formulations for treating diabetic foot ulcers.

Abstract: Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (?)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (?)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration.

Abstract: The present invention provides ?V?3 integrin cysteine loop domain agonists and antagonists (including peptide agonists and antagonists and analogs thereof), along with methods of using the same.

Abstract: Provided are methods of reducing the size of a tumor or inhibiting the growth of cancer cells in an individual or inhibiting the development of metastatic cancer by administering an effective amount of a soluble form of a co-stimulatory molecule from an antigen presenting cell and by reducing the activity of immunoregulatory T cells in the individual. Methods of reduction in the activity of immunoregulatory T cells involve removing them ex vivo or depleting or inactivating them in vivo. Also provided are cancer therapeutic compositions comprising a soluble form of a co-stimulatory molecule from an antigen presenting cell and an antibody specific for an intracellular antigen.

Abstract: A vehicle dispatch system includes a plurality of vehicle loading modules and a vehicle controlling server. The vehicle loading modules comprises a first wireless transmitting apparatus, a global positioning receiver for providing current coordinates of the vehicles, and a meter apparatus for transmitting an activating message when transporting a passenger. The vehicle controlling server comprises a geographic information system database apparatus for receiving and storing current coordinates of the vehicles, a plurality of road information, an operating interface platform for providing a user with a network apparatus to connect to the operating interface platform for inputting a calling request, and a second wireless transmitting apparatus for transmitting a request to a specified vehicle.

Abstract: The present invention relates generally to chemical agents useful in the prophylaxis and/or treatment of disease conditions and in particular chronic disease conditions such as inflammatory including allergic diseases, metastatic cancers and infection by pathogenic agents including bacteria, viruses or parasites. More particularly, the chemical agents contemplated by the present invention are selected from glycosaminoglycan (GAG) molecules derived from a larger GAG, GAG-like molecules which resemble GAGs in some of their characteristics but may be derived from a larger non-GAG polysaccharide and molecules having a GAG-like composite structure as well as agents which bind to the same sites as GAGs, GAG-like molecules or GAG-like composite molecules. The present invention also provides assays to identify GAG and GAG-like therapeutic agents including GAG-like composite structures as well as analogs, homologs and orthologs thereof.

Abstract: A translation graph is created using a plurality of reference sources that include translations between a plurality of different languages. Each entry in a source is used to create a wordsense entry, and each new word in a source is used to create a wordnode entry. A pair of wordnode and wordsense entries corresponds to a translation. In addition, a probability is determined for each wordsense entry and is decreased for each translation entry that includes more than a predefined number of translations into the same language. Bilingual translation entries are removed if subsumed by a multilingual translation entry. Triangulation is employed to identify pairs of common wordsense translations between a first, second, and third language. Translations not found in reference sources can also be inferred from the data comprising the translation graph. The translation graph can then be used for searches of a data collection in different languages.

Abstract: A Multi-Threshold CMOS NULL Convention Logic asynchronous circuit (MTNCL). The MTNCL circuit provides delay-insensitive logic operation with significant leakage power and active energy reduction. The MTNCL circuit is also capable of functioning properly under extreme supply voltage scaling down to the sub-threshold region for further power reduction. Four MTNCL architectures and four MTNCL threshold gate designs offer an asynchronous logic design methodology for glitch-free, ultra-low power, and faster circuits without area overhead.

Abstract: The phase locked loop has a phase-frequency detector (PFD), a loop filter (LF), a voltage controlled oscillator (VCO), and a 3-stage frequency divider. The PFD receives a reference signal and a feedback signal to determine phase and frequency errors. The LF), coupled to the phase-frequency detector, filters the phase and frequency errors to generate a control voltage. The VCO, coupled to the loop filter, generates a VCO output signal according to the control voltage. The 3-stage frequency divider, coupled to the voltage controlled oscillator, divides the frequency of the VCO output signal 3 times to generate the feedback signal. The 3-stage frequency divider comprises three cascaded frequency dividers with different rangers of operating frequencies.

Abstract: Medical imaging often involves the collective use of information presented in multiple images of an individual, such as images generated through different imaging modalities (X-ray, CT, PET, etc.) The use of a composite of these images may involve image registration to adjust for the variable position and orientation discrepancies of the individual during imaging. However, registration may be complicated by soft tissue deformation between images, and implementations (particularly pure software implementations) of the mathematical models used in image registration may be computationally complex and may require up to several hours. Hardware architectures are presented that apply the mathematical techniques in an accelerated manner, thereby providing near-realtime image registration that may be of particular use for the short timeframe requirements of surgical environments.

Abstract: Disclosed is an apparatus for performing mass spectrometry and a method of analyzing a sample through mass spectrometry. In particular, the disclosure relates to an apparatus capable of ambient mass spectrometry and mass spectral imaging and a method for the same. The apparatus couples laser ablation, flowing atmospheric-pressure afterglow ionization, and a mass spectrometer.

Abstract: A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures.

Abstract: A pixel-based video encoding apparatus includes a block prediction unit, a residual image generation unit, a pixel prediction unit, and an entropy-coding unit. The block prediction unit performs temporal or spatial prediction between a reference image and a current image in order to generate a prediction block corresponding to a current block to be encoded. The residual image generation unit generates a residual image block composed of a residual signal corresponding to a difference between pixels of the prediction block and pixels of the current block. The pixel prediction unit determines whether to apply differential pulse coded modulation to each of pixels of the residual image block based on a rate distortion optimization value. The entropy-coding unit performs entropy-coding on the residual image block.

Abstract: The present invention relates to systems, devices, and methods for performing biological reactions. In particular, the present invention relates to the use of lipophilic, water immiscible, or hydrophobic barriers in sample separation, purification, modification, and analysis processes.

Abstract: Receivers and reception methods conduct spread spectrum reception using the energy of multiple bits, preferably a substantial number of bits, in a packet for correct alignment of the spreading code at the receiver. Code acquisition, as well as packet detection and acquisition are provided by embodiments of the invention. Preferred embodiment receivers and reception methods provide packet detection at low SINR looking at energy of multiple bits of the packet, frame synchronization using short preamble, timing recovery at low SINR looking at energy of multiple bits of the packet, quick code acquisition using parallel search for all possible code phases, code acquisition at low SINR, and tracking of acquired timing and code phase. Preferred embodiment receivers and reception methods use the energy of multiple bits for making decisions.

Abstract: A window with an integral solar heat-absorber is provided in a compact, low-cost package. Two transparent panes are separated from one another to provide a first passageway for receiving a working fluid. The periphery of the panes is secured in a frame in which a heat exchanger is also secured, the heat exchanger having a second passageway for the working fluid and a third passageway for a service fluid. The first and second passageways are coupled to make a working fluid circuit.

Abstract: A method for analysis of distributed device rule-sets for compliance with global policies includes enabling an administrator to specify a network topology with intercommunicating elements and parameters required to secure the intercommunication with access control elements of the network topology; establishing connections to the access controls elements to capture a snapshot configuration of device rule-sets of the access control elements; enabling the administrator to specify a set of global access constraints with reference to the access control elements; enabling the administrator to select between exhaustive analysis and statistical analysis; conducting the selected analysis to determine violations by the device rule-sets that fail to comply with the set of global access constraints, wherein statistical analysis quantitatively characterizes a level of compliance without conducting analysis of all potential network paths; and providing results of the selected analysis to the administrator through a graphic