Abstract: A degradable composite comprising a degradable matrix, a first fiber type and a second fiber type, wherein the first fiber type has a different rate of degradation to that of the second fiber type.
Type:
Grant
Filed:
September 21, 2007
Date of Patent:
May 22, 2012
Assignee:
University of Nottingham
Inventors:
Christopher Douglas Rudd, Andrew James Parsons, Gavin Stuart Walker
Abstract: Drilling fluids comprising graphenes and nanoplatelet additives and methods for production thereof are disclosed. Graphene includes graphite oxide, graphene oxide, chemically-converted graphene, and functionalized chemically-converted graphene. Derivatized graphenes and methods for production thereof are disclosed. The derivatized graphenes are prepared from a chemically-converted graphene through derivatization with a plurality of functional groups. Derivatization can be accomplished, for example, by reaction of a chemically-converted graphene with a diazonium species. Methods for preparation of graphite oxide are also disclosed.
Type:
Grant
Filed:
July 8, 2010
Date of Patent:
May 22, 2012
Assignee:
William Marsh Rice University
Inventors:
James M. Tour, Howard K. Schmidt, Jay R. Lomeda, Dmitry V. Kosynkin, Condell D. Doyle
Abstract: The invention provides compounds of formula I: wherein Y is F or Br; or a pharmaceutically acceptable salt thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof, and methods of inhibiting cancer cells.
Type:
Grant
Filed:
November 14, 2008
Date of Patent:
May 22, 2012
Assignee:
Wayne State University
Inventors:
Jerome P. Horwitz, Lisa Polin, Stuart T. Hazeldine, Thomas H. Corbett
Abstract: Apparatus and methods for therapy delivery are disclosed. In one embodiment, a therapy delivery system includes a plurality of movable components including a radiation therapy nozzle and a patient pod for holding a patient, a patient registration module for determining a desired position of at least one of the plurality of movable components, and a motion control module for coordinating the movement of the least one of the plurality of movable components from a current position to the desired position. The motion control module includes a path planning module for simulating at least one projected trajectory of movement of the least one of the plurality of moveable components from the current position to the desired position.
Type:
Grant
Filed:
April 7, 2011
Date of Patent:
May 22, 2012
Assignee:
Loma Linda University Medical Center
Inventors:
Chieh C Cheng, David A Lesyna, Michael F Moyers
Abstract: Disclosed is a skull endosseous implant adapted to be implanted in the subject's skull to provide an access channel. A variety of sensor means may be installed in the access channel for monitoring the intracranial status of the subject. The present invention further provides a kit containing the skull endosseous implant.
Abstract: Described herein are compositions and methods for treating cancer, comprising administering to an individual having cancer an agent to prevent MIC shedding (initiated at the alpha-3 ectodomain of MIC) by a tumor cell. Also provided herein are screening assays for identifying, or testing the efficacy of, an agent for increasing sensitivity of a tumor to immune cell-mediated killing.
Abstract: A method of fabricating organic solar arrays for application in DC power supplies for electrostatic microelectromechanical systems (MEMS) devices. A solar array with 20 miniature cells (as small as 1 mm2) interconnected in series is fabricated and characterized. Photolithography is used to isolate individual cells and output contacts of the array, whereas the thermal-vacuum deposition is employed to make the series connections of the array. With 1 mm2 for single cell and a total device area of 2.2 cm2, the organic solar array based on bulk heterojunction structure of ?-conjugated polymers and C60 derivative (6,6)-phenyl C61 butyric acid methyl ester produces an open-circuit voltage of 7.8 V and a short-circuit current of 55 ?A under simulated air mass (AM) 1.5 illumination with an intensity of 132 mW/cm2. The present method can be used in the fabrication of microarrays as small as 0.01 mm2.
Abstract: With a vehicle seat arranging structure, a second-row passenger-side seat may be placed in a rearward slide position by sliding the second-row passenger-side seat toward the rear of a vehicle by 150 millimeters so that the second-row passenger-side seat is closer to the rear of the vehicle than the second-row driver-side seat. In addition, each of the second-row driver-side seat and the second-row passenger-side seat may be placed in an obliquely-inward frontward-oriented position by swiveling each of the second-row driver-side seat and the second-row passenger-side seat from the frontward-oriented position 10 degrees inward in the vehicle-width direction. In this way, the sense of distance between the occupants seated in the second-row driver-side seat and the second-row passenger-side seat is reduced. As a result, it is possible to promote communication between these occupants (to make it easier for these occupants to communicate with each other).
Type:
Grant
Filed:
December 19, 2008
Date of Patent:
May 22, 2012
Assignees:
Toyota Jidosha Kabushiki Kaisha, The University of Tokyo
Abstract: A passive tag receiving a reader signal provided by a reader is disclosed. The passive tag includes an antenna, an oscillator circuit, and an internal chip. The antenna receives the reader signal. The reader signal is within an operation frequency band. The oscillator circuit is coupled to the antenna and generates a frequency signal. The internal chip processes the reader signal according to power provided by the reader signal and the frequency signal when the reader signal is received and the frequency signal is generated.
Type:
Grant
Filed:
February 12, 2009
Date of Patent:
May 22, 2012
Assignee:
National Taiwan University of Science and Technology
Abstract: A tunable current driver comprising a semiconductor memory device and a selective transistor is provided, in which one of the source/drain pair of the semiconductor memory device is electrically coupled with a lighting device, and one of the source/drain pair of the selective transistor is electrically coupled with the gate electrode of the semiconductor memory device. The semiconductor memory device not only acts as “drive transistor” to drive the lighting device, but also is capable of adjusting the threshold voltage thereof.
Abstract: The present invention provides a complementary-conducting-strip (CCS) structure for miniaturizing microwave transmission line. The CCS structure comprises a substrate; a transmission part formed on the substrate, the transmission part consisted of M metal layers and at least one connecting arm extending from the metal layers to connect to an adjacent CCS structure, the M metal layers interlaminated M?1 dielectric layer(s) perforating a plurality of first metal vias to connect the M metal layers, wherein M?2 and M is a nature number; and a frame part formed on the substrate, the frame part surrounding the transmission part and consisted of M?1 metal frame(s), the M?1 metal frame(s) interlaminated M?2 dielectric frame(s) perforating a plurality of second metal vias to connect the metal frames.
Abstract: The invention provides an allergy prevention method or treatment method, diets and oral drugs enabling prevention/treatment of allergic symptoms without trouble such as systemic adverse reaction, immune deficiency and the like caused by transdermal/intravenous administration of TGF-?. The allergy prevention method or treatment method is to orally administer 100 ?g/kg or more of transforming growth factor-beta (TGF-?) relative to a weight of an administration target body and thereby selectively suppress Th2 immune response, while with respect to the diets and oral drugs, the content is set to contain an effective amount of transforming growth factor-beta (TGF-?) therein.
Abstract: The subject invention is drawn to ellagitannin metabolites (e.g., urolithin) that find use in treating or preventing a neoplastic disease in a subject.
Type:
Grant
Filed:
April 26, 2007
Date of Patent:
May 22, 2012
Assignee:
The Regents of the University of California
Abstract: This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo.
Type:
Grant
Filed:
December 10, 2004
Date of Patent:
May 22, 2012
Assignees:
The Scripps Research Institute, The Regents of the University of California
Inventors:
Peter G. Schultz, Lei Wang, John Christopher Anderson, Jason Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan Aaron Mehl, Miro Pastrnak, Steven William Santoro, Zhiwen Zhang
Abstract: An optical system suitable for use in an optical instrument such as a handheld optical probe, the optical system including a scanning element and an objective, the objective including a variable focus lens that can be electronically controlled to change the focal length of the optical system. In some embodiments, the optical system can axially and laterally scan a subject material by sequentially focusing at an axial depth using the variable focus lens and laterally scanning the material at that depth using the scanning element.
Type:
Grant
Filed:
October 20, 2008
Date of Patent:
May 22, 2012
Assignee:
University of Central Florida Research Foundation, Inc.
Inventors:
Jannick P. Rolland, Kevin P. Thompson, Supraja Murali
Abstract: The present invention relates to an optical modulating device with frequency multiplying technique for electrical signals, which primary comprises a mixer, which generates a mixed data signal from a first electrical signal and a second electrical signal. The mixed data signal is then received by a first phase shift device to have its phase shifted and becomes a first shifted signal. The first electrical signal is further received by a second phase shift device to have its phase shifted and becomes a second shifted signal. The present invention further comprises an integrated electro-optic modulator (Mach-Zehnder modulator), which is used to receive an input optical signal, the mixed data signal, the first shifted signal, the second shifted signal and the first electrical signal mentioned above, the integrated electro-optic modulator will then modulates the input optical signal into a frequency multiplying output optical signal that carries the first electrical signal and the second electrical signal.
Type:
Grant
Filed:
April 2, 2009
Date of Patent:
May 22, 2012
Assignee:
National Chiao Tung University
Inventors:
Jyehong Chen, Chun-Ting Lin, Sheng-Peng Dai, Peng-Chun Peng, Po-Tsung Shih, Sien Chi
Abstract: The present invention provides systems and methods for monitoring tissue regions. In particular, the present invention provides systems and methods for detecting changes in tissue regions over a period of time. In some embodiments, the systems and methods of the present invention are used to evaluate the effectiveness of a particular treatment of a tissue region. In some embodiments, the systems and methods employ functional diffusion map algorithms for imaging changes in tissue regions over time and/or in response to therapeutic interventions.
Type:
Grant
Filed:
April 11, 2008
Date of Patent:
May 22, 2012
Assignee:
The Regents of the University of Michigan
Inventors:
Brian D. Ross, Alnawaz Rehemtulla, Thomas L. Chenevert, Charles R. Meyer, Kuei C. Lee, Kenneth Pienta, Maha Hussein, Anne Schott
Abstract: A separator of a battery includes a porous membrane and a modifier layer disposed on a surface of the porous membrane, wherein a material of the modifier layer is a dried mixture of a phosphorus source having a phosphate radical, a trivalent aluminum source, and a metallic oxide in a liquid phase solvent.
Type:
Grant
Filed:
February 25, 2011
Date of Patent:
May 22, 2012
Assignees:
Tsinghua University, Hon Hai Precision Industry Co., Ltd.
Abstract: The present application discloses a method for monitoring abnormal state of Internet information. The method includes obtaining frequency data for current date common words appearing on the current date web pages, combining with a hot words dictionary that Internet users focuses on to determine a list of current date keywords related to the Internet information, determining a weight of each current date keyword, determining an abnormal threshold of the current date keywords, and detecting an abnormal level of the current date keywords to determine current date hot Internet information. The disclose method further calculates an abnormal level of keywords by monitoring the change in the hot words frequency in the Internet information, and generates warning for the abnormal level of hot words frequency change, which allows the Internet users to respond at the first moment.
Abstract: Cochlear implant performance is improved by extracting pitch information and encoding such pitch information into the processor of a cochlear implant. One embodiment of the invention is to explicitly extract the pitch and deliver it to the cochlear implant by co-varying the stimulated site and rate. Another embodiment of the invention is to implicitly encode the pitch information via a code book that serves as the carrier of stimulation in the cochlear implant.
Type:
Grant
Filed:
July 20, 2007
Date of Patent:
May 22, 2012
Assignee:
The Regents of the University of California