Abstract: A temperature-regulating fiber may include a spun phase change polymeric material that may include a plurality of phase change polymer blocks. The fiber may have a fixity ratio of at least 80% and a recovery ratio of at least 74%.
Abstract: A non crystalline or low crystallinity cellulose is able to be formed into a medicine tablet medium. A method of making a tablet of non crystalline or low crystallinity cellulose comprises providing cellulosic material, adding an effective acid in an amount effective to at least wet the cellulosic material, mixing the cellulosic material and acid under conditions effective to form an essentially uniformly wet condition, letting the mixture sit at ambient conditions for a period of time sufficient to form a viscous fluid, adding water or other diluent in an amount sufficient to lower the acid concentration and to form a slurry, dewatering the slurry, removing any residual acid from the dewatered slurry and forming the tablet.
Abstract: The present invention relates to methods for promoting somatic embryogenesis from a tissue or organ of a plant, by overexpressing a Wuschel gene in said tissue or organ. In one embodiment, such overexpression can be used as a silent selectable marker for transgenic plants. In another embodiment, such expression can be used to confer apomixis to a plant. In another embodiment, such overexpression can be used to create haploid plants, which can be used to produce dihaploid plants.
Abstract: The present invention provides compositions and methods for increasing the amount of active Syk protein kinase and or SHP-1 protein phosphatase in a cell. The compositions and methods are useful for increasing the efficacy of anti-neoplastic agents, such as those that target the CD33 protein, and which are used to treat leukemia. The invention thus provides for treatment of cancers, including leukemias. The invention also provides screening assays for anti-neoplastic agents in vitro. Methods of screening patients for responsiveness to anti-CD33 treatments are also provided.
Type:
Grant
Filed:
October 28, 2005
Date of Patent:
July 12, 2011
Assignee:
The Regents of the University of California
Abstract: A method of generating a holographic diffraction pattern and a holographic lithography system. The method involves defining at least one geometrical shape; generating at least one line segment to represent the at least one geometrical shape; calculating a line diffraction pattern on a hologram plane, including calculating the Fresnel diffraction equation for an impulse representing the at least one line segment with a line width control term and a line length control term; and adding vectorially, where there are two or more line segments, the line diffraction patterns to form the holographic diffraction pattern. The method and system enables holographic masks to be generated without creating a physical object to record. The required shapes or patterns are defined in terms of a three-dimensional coordinate space and a holographic pattern is generated at a defined distance from the shapes in the coordinate space.
Type:
Grant
Filed:
August 23, 2005
Date of Patent:
July 12, 2011
Assignee:
University of Durham
Inventors:
Alan Purvis, Richard McWilliam, Nicholas Luke Seed, Gavin Lewis Williams, Peter Anthony Ivey, Andrew Maiden, Simon Johnson
Abstract: Compounds which are FK228 analogues of the general formula (I) or (I?), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.
Type:
Grant
Filed:
June 2, 2006
Date of Patent:
July 12, 2011
Assignee:
University of Southampton Highfield
Inventors:
Arasu Ganesan, Graham Keith Packham, Alexander Yurek-George, Alexander Richard Liam Cecil
Abstract: Methods and systems for realizing high resolution three-dimensional (3-D) optical imaging using diffraction limited low resolution optical signals. Using axial shift-based signal processing via computer based computation algorithm, three sets of high resolution optical data are determined along the axial (or light beam propagation) direction using low resolution axial data. The three sets of low resolution data are generated by illuminating the 3-D object under observation along its three independent and orthogonal look directions (i.e., x, y, and z) or by physically rotating the object by 90 degrees and also flipping the object by 90 degrees. The three sets of high resolution axial data is combined using a unique mathematical function to interpolate a 3-D image of the test object that is of much higher resolution than the diffraction limited direct measurement 3-D resolution. Confocal microscopy or optical coherence tomography (OCT) are example methods to obtain the axial scan data sets.
Type:
Grant
Filed:
February 16, 2010
Date of Patent:
July 12, 2011
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: A channel estimation device for orthogonal frequency division multiplexing system and related method. The transmitting end transmits error detection signal of subcarrier, and the channel estimation is decided by whether the received signal at the receiving end is correct. Furthermore, in order to reduce the calculation complexity of the channel estimation, least square estimation is performed first, then MMSE estimation is performed to obtain more precise channel estimation, and singular value decomposition is utilized to reduce the calculation complexity of MMSE. The above-mentioned channel estimation method can obtain a better system efficiency in fast time variant channel.
Type:
Grant
Filed:
January 16, 2008
Date of Patent:
July 12, 2011
Assignee:
Southern Taiwan University of Technology
Abstract: A light emitting device (LED) structure formed on a Group IV-based semiconductor substrate is provided. The LED structure includes a Group IV-based substrate, an AlN nucleation layer formed on the Group IV-based substrate, a GaN epitaxial layer formed on the AlN nucleation layer, a distributed Bragg reflector (DBR) multi-layer structure formed on the epitaxial layer, and an LED active layer formed on the DBR multi-layer structure.
Abstract: A microfluidic device for preparing a mixture, has a mixer. The mixer includes a plurality of chambers, each chamber having a volume of at most 1 microliter, a first plurality of channels, each channel fluidly connecting 2 chambers, a plurality of chamber valves, each chamber valve controlling fluid flow out of one of the plurality of chambers, and a first plurality of channel valves, each channel valve controlling fluid flow through one of the first plurality of channels.
Type:
Grant
Filed:
July 22, 2008
Date of Patent:
July 12, 2011
Assignee:
The Board of Trustees of the University of Illinois
Inventors:
Paul J. A. Kenis, Joshua D. Tice, Sarah L. Perry, Griffin W. Roberts
Abstract: Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
Type:
Grant
Filed:
March 4, 2010
Date of Patent:
July 12, 2011
Assignee:
Board of Regents, The University of Texas System
Abstract: The present invention discloses a suspended nanochannel transistor structure and a method for fabricating the same. The transistor structure of the present invention comprises a substrate; a side gate formed on the substrate; a dielectric layer covering the substrate and the side gate; a suspended nanochannel formed beside the lateral of the side gate with an air gap existing between the suspended nanochannel and the dielectric layer; a source and a drain formed over the dielectric layer and respectively arranged at two ends of the suspended nanochannel. The electrostatic force of the side gate attracts or repels the suspended nanochannel and thus fast varies the equivalent thickness of the side-gate dielectric layer. Thereby, the on/off state of the element is rapidly switched, or the initial voltage of the channel is altered.
Type:
Grant
Filed:
December 17, 2008
Date of Patent:
July 12, 2011
Assignee:
National Chiao Tung University
Inventors:
Horng-Chih Lin, Chun-Jung Su, Hsing-Hui Hsu, Guan-Jang Li
Abstract: A nano-molding process including an imprint process that replicates features sizes less than 7 nanometers. The nano-molding process produces a line edge roughness of the replicated features that is less than 2 nanometers. The nano-molding process including the steps of: a) forming a first substrate having nano-scale features formed thereon, b) casting at least one polymer against the substrate, c) curing the at least one polymer forming a mold, d) removing the mold from the first substrate, e) providing a second substrate having a molding material applied thereon, f) pressing the mold against the second substrate allowing the molding material to conform to a shape of the mold, g) curing the molding material, and h) removing the mold from the second substrate having the cured molding material revealing a replica of the first substrate.
Type:
Grant
Filed:
September 15, 2005
Date of Patent:
July 12, 2011
Assignees:
The Board of Trustees of The University of Illinois, Dow Corning Corporation
Abstract: A gas or an insulating material having a relative dielectric constant of not more than 2.5 on average is interposed between a first wiring layer and a second wiring layer included in a multilayer wiring structure. Between a wiring of the first wiring layer and a wiring of the second wiring layer, a conductive connector is arranged. Between a predetermined wiring of the first wiring layer and a predetermined wiring of the second wiring layer, an insulating heat conductor having a relative dielectric constant of not more than 5 is arranged.
Type:
Grant
Filed:
August 24, 2007
Date of Patent:
July 12, 2011
Assignees:
National University Corporation Tohoku University, Foundation for Advancement of International Science
Abstract: Light Emitting Diodes (LEDs) where the emission region, usually a (Al,In,Ga)N layer, is structured for efficient light extraction, are disclosed. The structuring is designed for light extraction from thin films, such as a photonic crystal acting as a diffraction grating. In addition, the structuring controls the in-plane emission and allows new modes into which light will be emitted. Various electrode designs are proposed, including ZnO structures which are known to lead to both excellent electrical properties, such as good carrier injection, and high transparency. Alternatively, the (Al,In,Ga)N layer can be replaced by structures with other materials compositions, in order to achieve efficient light extraction.
Type:
Grant
Filed:
November 15, 2007
Date of Patent:
July 12, 2011
Assignee:
The Regents of the University of California
Inventors:
Aurelien J. F. David, Claude C. A. Weisbuch, Steven P. DenBaars, Stacia Keller
Abstract: The subject invention concerns biotin-conjugated platinum complexes that exhibit direct and indirect (immunological) antitumor cell activity. The subject invention also concerns the biotin-platinum complexes of the invention that have another molecule, such as an antibody, a ligand, a receptor, etc., bound to the biotin moiety. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the invention can also be used to treat or prevent infection by a virus or a bacterial or parasitic organism in vivo or in vitro.
Abstract: Compositions and methods of preventing or treating a breast cancer are disclosed. The composition and method can utilize an endothelin B agonist and a chemotherapeutic agent as active ingredients to treat a solid tumor in mammals, including humans. Alternatively, the composition and method can utilize an endothelin B antagonist and an optional angiogenesis inhibitor to treat a solid tumor in mammals, including humans.
Type:
Grant
Filed:
July 26, 2006
Date of Patent:
July 12, 2011
Assignee:
The Board of Trustees of the University of Illinois
Abstract: Methods for measuring expansion of a test sample. One method includes establishing a diffraction slit between two blades, with the position of at least one of the blades being dependent upon the length of a test sample of material. As the temperature of the sample changes, the width of the slit changes. Light is projected through the slit onto a target and an diffraction pattern is measured. Changes in the light diffraction pattern correspond to the thermal expansion of the sample. Another method includes establishing a diffraction slit between two blades, with the position of at least one of the blades being dependent upon a length along a test sample of material. As a load is applied to the test sample, the width of the slit changes. Changes in the light diffraction pattern correspond to Young's Modulus for the sample.
Abstract: The present inventions relate to compositions and methods for providing stress tolerant transgenic plants comprising a RING domain zinc-finger motif transcription factor protein. More particularly, the invention relates to compositions and methods comprising a RING-H2 domain transcription factor protein for providing drought and salt tolerant plants, in particular comprising a recombinant XERICO gene and protein.
Type:
Grant
Filed:
July 12, 2006
Date of Patent:
July 12, 2011
Assignee:
Board of Trustees of Michigan State University
Abstract: A gaming machine switchable between an insurance mode and a non-insurance mode and which activates insurance compensation irrespective of a result of a game when a predetermined condition is established and a playing method thereof are disclosed. In accordance therewith, when a bet value or a payout value to be paid out includes a value less than one credit, that value is accumulatively stored as a fractional value, and the mode is switched from an insurance mode to a non-insurance mode when the accumulatively added fractional values reach a predetermined value or the number of unit games in which the fractional value is accumulatively added reaches a predetermined number.