Abstract: Novel stable, concentrated, biologically active and ready-to-use lipid-comprising drug delivery complexes and methods for their production are described. The biological activity of the complexes produced are comparable to the formulations prepared according to the prior art admixture method and upon purification, the complexes produced by the method of this invention are 50 to 500 fold more concentrated than the complexes formed by admixture. The method described herein provides for the large scale production of lipid-comprising drug delivery systems useful for gene therapy and other applications.

Abstract: Provided is a tag identification method in an RFID system. A tag identification method generates a query tree according to a query and a response between an RFID reader and a tag to identify the tag. In the method, a query message is transmitted from the RFID reader to the tag. A response message for the query message is received from the tag. Herein, the query tree is generated in the reverse order of a string owned by the tag. The query tree is generated in the reverse order of the tag IDs in the query tree-based protocol to reduce the frequency of collisions between the tags, thereby making it possible to reduce the time taken to identify all the tags within the recognizable range of the RFID reader.

Abstract: A method of treating a central nervous system (CNS) disorder, comprises the steps of inserting into a patient's body first and second conduits so that distal ends of the first and second conduits open to a portion of the patient's CNS with direct access to cerebrospinal fluid (CSF) and a proximal end of the first conduit opens into a first reservoir of material to be introduced into the CSF and a proximal end of the second conduit opens to drain CSF withdrawn from the CNS in combination with the steps of detecting and analyzing brain activity of a patient and determining a chemical imbalance present in the CSF by one of a microassay of a sample of CSF withdrawn from the second reservoir and the detected and analyzed brain activity. Based on the determined chemical imbalance, the patient is treated by one of supplying an agent to the CSF via the first conduit and withdrawing a quantity CSF via the second conduit.

Abstract: The present invention describes a novel recombinant NADH recycling system that is used as a process for producing reduced compounds. In a specific embodiment, the reduced compounds include ethanol, succinate, lactate, a vitamin, a pharmaceutical and a biodegraded organic molecule. The NADH recycling system effects metabolic flux of reductive pathways in aerobic and anaerobic environments.

Abstract: A garment for electrically stimulating muscles is provided to be used for, e.g., rehabilitation or exercise whereby an electrode can be conveniently provided at such a position as allowing the electrode to stimulate the nerve-muscular junction of a muscle to be moved in toning up the muscle through electrical stimulation on the muscle by taking advantage of the muscular contraction caused by electrically stimulating the muscle.

Abstract: An image interpolating method and apparatus, in which horizontal and vertical Differences of Absolute Inter-channel Differences (DAIDs) are calculated from a color filter array (CFA) image, and an unknown pixel is interpolated in horizontal and vertical directions estimated in consideration of the DAIDs of R, G, and B pixels. Therefore, the image interpolating method and apparatus provide a large Peak Signal and Noise Ratio (PSNR), a Structural Similarity (SSIM), and high visual quality images.

Abstract: The present invention relates to novel proteins, referred to herein as amidated glial cell line-derived neurotrophic factor (GDNF) peptides (or “Amidated Dopamine Neuron Stimulating peptides (ADNS peptides)”), that are useful for treating brain diseases and injuries that result in dopaminergic deficiencies.

Abstract: The present invention relates to retroviral vectors, particularly lentiviral vectors, pseudotyped with Sindbis envelope and targeted to specific cell types via a targeting moiety linked to the envelope.

Abstract: A field electron emitter includes a thin film layer including a carbon nanotube (“CNT”) disposed on a substrate, wherein the thin film layer includes nucleic acid.

Abstract: A method and corresponding system for providing a uniform nanowire array including uniform nanowires composed of at least three elements is presented. An embodiment of the method includes growing an array of two-element nanowires, and thereafter uniformly doping or alloying each two-element nanowire, with respect to each other two-element nanowire, with at least one doping or alloying element through a wet chemical synthesis with a precursor solution, to produce the uniform array of nanowires composed of at least three elements. The two-element nanowire can include Zn and O, and the at least one doping or alloying element can be Mg, Cd, Mn, Cu, Be, Fe, and Co. Applications of the three-element nanowire array include solar cells and light emitting diodes with improved efficiencies over existing technologies.

Abstract: An X-ray condensing method and its device are provided with an X-ray mirror that has a wavefront adjustable function to finely adjust a wavefront of a reflecting X-ray, measure an X-ray intensity distribution in the vicinity of a focus, measure an X-ray intensity distribution in the vicinity of the X-ray mirror or use a known X-ray intensity distribution of an incident X-ray, calculate a complex amplitude distribution at the reflective surface by using a phase restoration method from the X-ray intensity distribution in the vicinity of the focus and the X-ray intensity distribution in the vicinity of the reflective surface, calculate a wavefront aberration of an X-ray condensing optical system from the complex amplitude distribution, and control the reflective surface of the X-ray mirror with the wavefront adjustable function so that the wavefront aberration is minimized.

Abstract: The present invention includes compositions and methods for making and using a rapid dissolving, high potency, substantially amorphous nanostructured aggregate for pulmonary delivery of tacrolimus and a stabilizer matrix comprising, optionally, a polymeric or non-polymeric surfactant, a polymeric or non-polymeric saccharide or both, wherein the aggregate comprises a surface area greater than 5 m2/g as measured by BET analysis and exhibiting supersaturation for at least 0.5 hours when 11-15-times the aqueous crystalline solubility of tacrolimus is added to simulated lung fluid.

Abstract: A biopsy device is described. In one aspect, the biopsy device includes a scoop-shaped blade with a distal, pointed tip. A handle is operatively coupled to a proximal end of the scoop-shaped blade. The scoop-shaped blade and handle combination of the biopsy device are configured to provide a tissue biopsy to a practitioner responsive to a manually directed biopsy operation on a patient.

Abstract: The present invention relates to a cell culture device which includes: a cell culture container comprising a container body and a neck connecting to the container body wherein the container contains a top wall, a bottom wall having a first opening, and at least one side wall to define a cell culture zone, and an end of the neck has a second opening for cells or culture media being injected into the cell culture zone; a biosensor chip having a detective surface which faces the top wall of the cell culture container; and a fastening component for the biosensor chip being fastened in the first opening of the bottom wall. The cell culture of the present invention can be used for real-time detection of the cell growth and further for drug screening.

Abstract: The present invention provides systems and methods for improving the efficiency of a transient gene delivery system to differentiating embryonic stem (ES) cells by serum starving the targeted cells for one to three days prior to transfection. Such a serum starvation surprisingly resulted in increased expression of a constitutively-controlled plasmid from 50.4% to 83.2% of the population and increased expression of a promoter/enhancer controlled plasmid from ˜1.4% to ˜3.7% of the population.

Abstract: A shared key management method for a Supervisory Control And Data Acquisition (SCADA) system in which a master terminal unit (MTU), a plurality of sub master terminal units (SUB-MTUs), and a plurality of remote terminal units (RTUs) are configured in a sequential hierarchy, is provided.

Abstract: The present invention provides an NAT (Network Address Translator) traversal method in Session Initiation Protocol (SIP) for solving the problems of SIP in Internet phone (VoIP) under current Internet environment. In other words, the present invention solves the SIP problems caused by NAT (Network Address Translator) that P2P (Peer to Peer) transmission cannot traverse the NAT firewall directly.

Abstract: The present invention relates to methods and compositions for treating and/or preventing inflammation associated with viral infection and solid organ transplant rejection. In particular, the present invention provides therapeutics for impairing the expansion and function of autoreactive T cells, NK cells and/or NKT cells, by modulating NKG2D.

Abstract: A pixel output line (14) is independently provided for each of the pixels arranged in a two-dimensionally array within a pixel area so that pixel signals can be sequentially written in a plurality of memory sections (22) through the pixel output lines (14). When a plurality of frames of pixel signals are held in the memory sections (22), the pixel signals corresponding to two arbitrarily selected frames are read and respectively stored in sample-and-hold circuits (61 and 62), and their difference is obtained. Then, the difference signals corresponding to a predetermined range of the image are integrated, and the integrated value is compared with a threshold. If the integrated value exceeds the threshold, it is presumed that a change in an imaging object has occurred, and a pulse generation circuit (66) generates a trigger signal.

Abstract: The present invention relates to a method of time-domain magnetic resonance imaging and device thereof. The method includes transiently exciting a sample; receiving a signal emitted form the sample; and processing the received signal without Fourier transformation to acquire an image. The device includes an excitation device, a detecting coil and an operating circuit to process a received emitting signal and generating an image, wherein the received emitting signal is a time-domain signal free from Fourier transformation. The time of generating an image can be reduced dramatically by the present invention.