Abstract: A device for measuring a molecule, wherein a gel substrate material (200) comprises a gel (220) containing a solvent in the network structure thereof and a molecular chain (210), and a cantilever (100) is bound with the molecular chain (210) by a covalent bonding or a physical bonding and pulls up the molecular chain (210) through the above bonding, and wherein the force loaded when the cantilever (100) pull up the molecular chain (210) is measured and the interaction between polymer chains acting between the gel (200) and the molecular chain (210) is detected. The above device can be used for measuring the interaction between molecules, and in particular, can construct an experiment system for measuring the non-covalent bonding interaction between polymer chains at a molecular level.

Abstract: A method of Digital to Analogue conversion of an input signal Do for suppressing the effect of clock-jitter in a Delta-Sigma analogue to digital converter, or class D amplifier, comprises charging a capacitor to a reference voltage value (Vref) during a first phase (?) of a clock signal, discharging the capacitor during a second phase (?2) of the clock signal, wherein the discharge is regulated by a biased transistor, responsive to the voltage on the capacitor, in a first part of the second phase to provide an approximately constant discharge current, and regulated in a second part of the second phase for rapidly discharging the capacitor before the end of the second phase; and providing an output (Ud, OUT) as a function of the discharge current and the input signal Do. The output signal Ud, may be applied as a feedback signal to a loop filter in a Delta-Sigma converter. Alternatively, the output may represent the output of a Class D amplifier.

Abstract: The present invention relates to a limited slip differential with friction using a pressure generating device. The limited slip differential includes a first side pinion gear and a second side pinion gear opposite to each other, a pair of differential pinion gears each of which is rotated in engagement with the first and second side pinion gears friction plates arranged at rear sides of the first and second side pinion gears friction plates arranged at rear sides of the first and second side pinion gears, and a pressure generating device having a cover gear and a piston gear and being constructed such that the cover gear and the piston gear engage with the second side pinion gear and first side pinion gear, respectively, and can be displaced away from each other in a longitudinal direction of the device.

Abstract: A process is provided of introducing an RNA into a living cell to inhibit gene expression of a target gene in that cell. The process may be practiced ex vivo or in vivo. The RNA has a region with double-stranded structure. Inhibition is sequence-specific in that the nucleotide sequences of the duplex region of the RNA and of a portion of the target gene are identical. The present invention is distinguished from prior art interference in gene expression by antisense or triple-strand methods.

Abstract: In an associative memory, when a reference data having the minimum distance with respect to an input data is detected as winner, it is determined whether or not a distance between the input data and winner is less than a threshold value. If the distance is less than the threshold value, it is determined that the reference data detected as winner matches with the input data, and then, a rank of the reference data is improved. If the distance is more than the threshold value, it is determined that the reference data is data different from the input data, and then, the input data is written as new reference data to the associative memory and replaces the reference data with the lowest rank. The upper positions of rank form as a long-term memory, and the lower positions thereof form as a short-term memory.

Abstract: A formulation containing one or more biologically active substances dissolved, dispersed, emulsified, or suspended within a vehicle of one or more citric acid esters and/or citric acid ethers. Methods for making and using are disclosed, as are kits for administration of the pharmaceutical formulation.

Abstract: Provided herein are methods of screening compounds, gene sequences, and gene products in bacteria for agents that are protective against oxidative DNA damage in a human or animal. Gene sequences identified by these screens can also be used in diagnostic assays that identify subjects at increased risk for oxidative DNA damage. Pharmaceutical compositions that include DNA protective agents identified by these screens are also provided.

Abstract: The present invention provides a perfluorocarbon ionomer membrane with aligned fibril-like nanostructures and its preparation method.

Abstract: A device for combining tomographic images with human vision using a half-silvered mirror to merge the visual outer surface of an object (or a robotic mock effector) with a simultaneous reflection of a tomographic image from the interior of the object. The device maybe used with various types of image modalities including ultrasound, CT, and MRI. The image capture device and the display may or may not be fixed to the semi-transparent mirror. If not fixed, the imaging device may provide a compensation device that adjusts the reflection of the displayed ultrasound on the half-silvered mirror to account for any change in the image capture device orientation or location.

Abstract: Disclosed are fine powder of waste polyurethane foam and a manufacturing method thereof. According to this invention, fine powder of waste polyurethane foam can be manufactured using a crushing process including primary and secondary coarse crushing steps and a fine grinding step and a classification process, thereby solving conventional problems of the deterioration of the properties and the difficulty forming a desired cell structure, due to the use of waste polyurethane powder having a large particle diameter, and widening the range of waste polyurethane that can be recycled.

Abstract: The present invention provides compositions suitable for use as biomarkers of vulnerable plaques as well as methods for the use of such compositions. In preferred embodiments, specific molecular imaging agents are provided that permit the selective identification of vulnerable plaques in coronary and other arteries using non-invasive imaging methods. Such specific molecular imaging agents comprise a binding partner linked to a detectable label that can be used in vivo to visualize vulnerable plaques. In certain preferred embodiments, the binding partner is a peptide that binds selectively to a component of a vulnerable plaque. In other preferred embodiments, the binding partner is an antibody that binds selectively to a component of a vulnerable plaque. In other preferred embodiments, the binding partner is a portion of a polypeptide displayed by a bacteriophage that binds selectively to a component of a vulnerable plaque.

Abstract: Techniques are described for generating digital carrier multi-band user codes for a baseband ultra-wideband (UWB) signal. The digital carrier multi-band user codes comprise spreading codes that enable multiple access in a UWB system. The user codes are digital, lead to baseband operation, and provide flexibility in handling narrow band interference (NBI) within the UWB system. In one embodiment, the invention provides a method comprising generating digital carrier multi-band user codes for a baseband ultra-wideband (UWB) signal of a user in an UWB system.

Abstract: The present invention provides titanium dioxide/single-walled carbon nanotube composites (TiO2/SWCNTs), articles of manufacture, and methods of making and using such composites. In certain embodiments, the present invention provides membrane filters and ceramic articles that are coated with TiO2/SWCNT composite material. In other embodiments, the present invention provides methods of using TiO2/SWCNT composite material to purify a sample, such as a water or air sample.

Abstract: The present invention relates to the quarternized amino glucosamine, it can exert an anticancer effect via induction of apoptosis in a dose and time dependant manner through which an anticancer treatment effect can be increased.

Abstract: A method and system for animating a chemical mechanism begins with user selections of an initial chemical structure and an operation to be performed on the chemical structure via a graphical user interface. Based on these selections, an engine determines a resulting modified chemical structure and a chemical mechanism animation. The chemical mechanism animation includes the initial chemical structure, a modified chemical structure and one or more sequential transition frames illustrating a transition between the initial chemical structure and the modified chemical structure. The chemical mechanism is transmitted to a visual display or another readable medium.

Abstract: Provided are diagnostic and therapeutic methods of treating sarcoidosis comprising the use of microbial catalase-peroxidase protein, its peptide fragments, or derivatives thereof.

Abstract: A transfection reagent and a method for enhancing transfection efficiency are described. A nucleic acid is provided, and a disaccharide is added as a transfection reagent. The disaccharide is composed of two identical monosaccharides. The transfection reagent is then applied to cells to introduce the nucleic acid into the cells.

Abstract: An optical fiber includes a cladding with a material having a first refractive index and a pattern of regions formed therein. Each of the regions has a second refractive index lower than the first refractive index. The optical fiber further includes a core region and a core ring having an inner perimeter, an outer perimeter, and a thickness between the inner perimeter and the outer perimeter. The thickness is sized to reduce the number of ring surface modes supported by the core ring.

Abstract: A frequency compensation method for voltage-mode switching regulators is disclosed. A lowpass filter and a bandpass filter are employed in the two signal paths into the dual inputs of PWM comparators. In one embodiment, two zeros are generated to compensate for the L-C output filter poles. Stable operation, low output voltage ripple and fast load transient response are achieved; while the power consumption of error amplifier and the area for implementing on-chip passive components are greatly reduced.

Abstract: An electro-tactile display comprises at least one current source, arrayed electrodes, and a switching circuit for connecting each electrode to the current source or to ground. The electro-tactile display is characterized by selecting one or a plurality of electrodes from the arrayed electrodes and connecting the selected electrodes to the current source to provide current source electrodes, alternately connecting neighboring electrodes in the vicinity of said current source electrodes to the current source and to ground, connecting a plurality of remaining electrodes other than the neighboring electrodes to ground to provide ground electrodes, and providing electrical stimulation from the current source electrodes wherein the current source electrodes are spaced apart from the ground electrodes via the neighboring electrodes. Tactile sensations are presented by switching over the current source electrodes at a predetermined time interval.