Patents Assigned to University
  • Publication number: 20090170865
    Abstract: Provided is a method of inhibiting the growth of prostate cancer cells comprising administering an effective amount of DZ-50 (2-[4-biphenyl-4-sulfonyl)-piperazin-1-yl]-6,7-diisopropoxyquinazolin-4-yl-amine) to a patient in need thereof. In another aspect, a method is provided for inhibiting the initiation of prostate cancer comprising administering an effective amount of DZ-50 to a patient in need thereof. In yet another aspect, a method is provided for inhibiting the formation of a prostate tumor-derived metastatic lesion comprising administering an effective amount of DZ-50 to a patient in need thereof. In any of the aforementioned methods, a quinazoline-based drug which induces apoptosis of a prostate cancer cell may be coadministered with DZ-50. Also provided is a composition comprising DZ-50, a quinazoline-based drug which induces apoptosis of a prostate cancer cell, and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: November 25, 2008
    Publication date: July 2, 2009
    Applicant: University of Kentucky Research Foundation
    Inventors: Natasha Kyprianou, Jason B. Garrison, Ching-Shih Chen
  • Publication number: 20090167438
    Abstract: Disclosed is a Doherty amplifier which includes a carrier amplifier for always performing a signal amplification operation regardless of a level of an input signal, a peaking amplifier for performing an amplification operation, starting from a high power output where a level of an input signal is equal to or greater than a predetermined level, an output combination circuit for combining and outputting outputs of the carrier amplifier and the peaking amplifier, and an input division circuit for dividing an input signal into the carrier amplifier and the peaking amplifier, the Doherty amplifier including a carrier amplifier output harmonic impedance tuning network which is installed at a rear end of the carrier amplifier so as to tune an output harmonic impedance of the carrier amplifier, and a peaking amplifier output harmonic impedance tuning network which is installed at a rear end of the peaking amplifier so as to tune an output harmonic impedance of the peaking amplifier.
    Type: Application
    Filed: February 20, 2008
    Publication date: July 2, 2009
    Applicant: Sungkyunkwan University Foundation for Corporate Collaboration
    Inventors: Youngoo Yang, Xi Yao, Hyun Chul Park, Sung Wook Kwon
  • Publication number: 20090170866
    Abstract: The invention described herein relates to methods and compositions useful in the diagnosis, treatment and management of cancers that express particular genes, including the moesin, caveolin 1, and/or yes-associated protein 1 genes.
    Type: Application
    Filed: November 10, 2006
    Publication date: July 2, 2009
    Applicants: Bristol-Myers Squibb Pharma Company, The Regents of the University of California
    Inventors: Richard S. Finn, Judy Dering, Dennis J. Slamon, Charles L. Ginther, Edwin A. Clark
  • Publication number: 20090166585
    Abstract: The present invention provides for a composition comprising an inorganic scintillator comprising a gadolinium halide, optionally cerium-doped, having the formula AnGdXm:Ce; wherein A is nothing, an alkali metal, such as Li or Na, or an alkali earth metal, such as Ba; X is F, Br, Cl, or I; n is an integer from 1 to 2; m is an integer from 4 to 7; and the molar percent of cerium is 0% to 100%. The gadolinium halides or alkali earth metal gadolinium halides are scintillators and produce a bright luminescence upon irradiation by a suitable radiation.
    Type: Application
    Filed: October 30, 2008
    Publication date: July 2, 2009
    Applicant: The Regents of the University of California
    Inventors: Edith Bourret-Courchesne, Stephen E. Derenzo, Shameka Parms, Yetta D. Porter-Chapman, Latoria K. Wiggins
  • Publication number: 20090170394
    Abstract: A method for making a thermionic electron source includes the following steps: (a) supplying a substrate; (b) forming a first electrode and a second electrode thereon; and (c) spanning a carbon nanotube film structure on a surface of the first electrode and the second electrode with a space defined between the thermionic emitter and the substrate.
    Type: Application
    Filed: October 23, 2008
    Publication date: July 2, 2009
    Applicants: Tsinghua University, HON HAI Precision Industry CO., LTD.
    Inventors: Peng Liu, Liang Liu, Kai-Li Jiang, Shou-Shan Fan
  • Publication number: 20090165559
    Abstract: A sensor is disclosed for analyzing information, such as interfacial interactions, found in various systems. A sensor is located proximate to an interface that is to be studied. The sensor is actuated in order to produce acoustical signals. The frequency of oscillation of the sensor is varied in order to enable the sensor to produce acoustical signals at different harmonics. The different acoustical signals are used to analyze the system at various distances from the surface of the sensor.
    Type: Application
    Filed: November 23, 2005
    Publication date: July 2, 2009
    Applicant: Drexel University
    Inventor: Ryszard M. Lec
  • Publication number: 20090168420
    Abstract: The optical element apparatus for two-dimensional controllable localized partition backlight module is disclosed. The optical element apparatus comprises of a plurality of optical units which include a plurality of point light sources, light guides and collimating sheets. The point light source is located at the center of the light guide. The light guide includes the incident surface, the bottom place connecting with the light incident surface, and the light output surface. There are micro structures on the bottom place of the light guide and the top surface of the collimating sheet.
    Type: Application
    Filed: December 26, 2007
    Publication date: July 2, 2009
    Applicant: National Chiao Tung University
    Inventors: Chung-Hao Tien, Yen-Hsing Lu, Yu-Kuo Cheng, Po-Yi Lu
  • Publication number: 20090168688
    Abstract: A relay station, including a delay information storage unit to store remaining delay information generated in a path from a target relay node to a destination node; an order determination unit to determine an order of processing service packets with a plurality of quality of service (QoS) levels using the remaining delay information, the service packets being received from a neighbor node; and a processing unit to process the service packets in the determined order.
    Type: Application
    Filed: April 2, 2008
    Publication date: July 2, 2009
    Applicants: Samsung Electronics Co., Ltd., Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Sunggook LIM, Jung Min SO, Mi-Sun DO, Jaiyong LEE
  • Publication number: 20090169463
    Abstract: This invention relates generally to forming an array of fullerene nanotubes. In one embodiment, a macroscopic molecular array is provided comprising at least about 106 fullerene nanotubes in generally parallel orientation and having substantially similar lengths in the range of from about 5 to about 500 nanometers.
    Type: Application
    Filed: August 22, 2006
    Publication date: July 2, 2009
    Applicant: William Marsh Rice University
    Inventors: Richard E. Smalley, Daniel T. Colbert, Hongjie Dai, Jie Liu, Andrew G. Rinzler, Jason H. Hafner, Kenneth A. Smith, Ting Guo, Pavel Nikolaev, Andreas Thess
  • Publication number: 20090169464
    Abstract: The present invention discloses a method for producing carbon nanocoils, which comprises: providing a metal substrate; depositing a tin precursor on the substrate; heating the substrate with the precursor to a predetermined temperature to form a catalyst on the substrate; placing the substrate in a quartz tube furnace; and introducing carbon source gas and protective gas into the quartz tube furnace to allow carbon nanocoils to grow on the surface of the catalyst. Another method for producing carbon nanocoils is also disclosed, which includes: depositing a mixed solution of iron acetate and tin acetate on a substrate; heating the substrate with the mixing solution to a predetermined temperature to form a catalyst on the substrate; placing the substrate in a quartz tube furnace; and introducing carbon source gas and protective gas into the quartz tube furnace to allow carbon nanocoils to grow on the surface of the catalyst.
    Type: Application
    Filed: May 29, 2008
    Publication date: July 2, 2009
    Applicant: National Taiwan University
    Inventors: Shuo-Hung Chang, Bing-Chen Wei, Neng-Kai Chang
  • Publication number: 20090170780
    Abstract: This invention relates to the use of ADNF polypeptides in the treatment of laser-induced retinal damage and related conditions.
    Type: Application
    Filed: April 20, 2006
    Publication date: July 2, 2009
    Applicant: Ramot at Tel Aviv University Ltd.
    Inventors: Illana Gozes, Michael Belkin
  • Publication number: 20090168151
    Abstract: Methods and corresponding apparatus for optical amplification in semiconductors, particularly indirect band-gap semiconductors, and most particularly in silicon. A first aspect of the invention employs certain doping elements to provide inter-band-gap energy levels in combination with optical or current-injection pumping. The doping element, preferably a noble metal and most preferably Gold, is chosen to provide an energy level which enables an energy transition corresponding to a photon of wavelength equal to the signal wavelength to be amplified. The energy transition may be finely “adjusted” by use of standard doping techniques (such as n-type or p-type doping) to alter the conduction and valence band energy levels and thereby also the magnitude of the energy transition. A second aspect of the invention relates to the use of a non-homogeneous heat distribution which has been found to lead to optical amplification effects.
    Type: Application
    Filed: January 25, 2009
    Publication date: July 2, 2009
    Applicant: Ramot At Tel Aviv University Ltd.
    Inventors: Shlomo Ruschin, Stanislav Stepanov
  • Publication number: 20090169634
    Abstract: The present invention provides a DNA vaccine, which comprises a DNA construct comprising an expression vector which is expressible in a eukaryotic cell, and a nucleotide fragment which comprises an IL-6-encoding sequence and an HPV E7-encoding sequence. In addition, the present invention also provides a pharmaceutical composition and a method of generating said DNA vaccine.
    Type: Application
    Filed: January 2, 2008
    Publication date: July 2, 2009
    Applicant: National Taiwan University
    Inventors: Wen-Fang Cheng, Chi-an Chen
  • Publication number: 20090170213
    Abstract: The present invention provides a method for high-throughput screening of enantiomeric excess (ee), comprising synthesizing a sensor made from an aggregate of gold nanoparticles whose surfaces have been elaborated with a chiral “host” that includes two optically pure binaphthol groups linked together by a diethanolamine bridge that is tethered via nitrogen to its associated gold nanoparticle, and in which aggregate the individual particles are held together by a bridging chiral “di-guest,” which contains an amino acid functionality at both ends and which interacts with the surface-bound hosts through hydrogen bonds.
    Type: Application
    Filed: May 23, 2007
    Publication date: July 2, 2009
    Applicant: University of Western Ontario
    Inventors: Nathan Jones, Silvia Mittler, Mohammad Nuruzzaman, Thomas Preston
  • Publication number: 20090171234
    Abstract: Featured are apparatuses for measuring bioimpendence of tissues of the cervix, more specifically the mammalian cervix. Also featured are methods for examining the tissues of the cervix for clinical or diagnostic purposes such as during routine gynecological examinations to determine early onset of labor in pregnant patients or to assess such tissues for the presence of abnormalities such as cancerous lesions in both pregnant and non-pregnant women. Also featured are methods for treating onset of early or pre-term labor that embody such devices, apparatuses and methods of the present invention. Also featured are systems embodying such devices, apparatuses and/or methods, where such systems preferably are configured to provide diagnostic and/or clinical information to further assist the diagnostician or clinician in diagnosing and/or examining pregnant or non-pregnant patients.
    Type: Application
    Filed: May 3, 2004
    Publication date: July 2, 2009
    Applicant: The Johns Hopkins University
    Inventors: Edith D. Gurewitsch, Melanie Ruffner, Kenny H. Ching, Somponnat Sampattavanich, Ashkon Shaahinfar, Yen S. Hoe, Elbert S. Hu
  • Publication number: 20090167711
    Abstract: A touch panel includes a substrate, a transparent conductive layer and a plurality of electrodes. The substrate has a first surface and a second surface opposite to the first surface. The transparent conductive layer is formed on the first surface of the substrate. The transparent conductive layer includes a plurality of separated carbon nanotube structures. The electrodes are electrically connected to the transparent conductive layer. Each electrode is connected with the end of at least one of the carbon nanotube structures such that each carbon nanotube structure is in contact with at least two opposite electrodes. Further, a display device using the above-described touch panel is also included.
    Type: Application
    Filed: September 29, 2008
    Publication date: July 2, 2009
    Applicants: Tsinghua University, HON HAI Precision Industry CO., LTD.
    Inventors: Kai-Li Jiang, Liang Liu, Shou-Shan Fan
  • Publication number: 20090169612
    Abstract: This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in a mammal. The method is particularly effective for protecting a mammal from a disease including cancer, a disease associated with allergic inflammation, or an infectious disease. Also disclosed are therapeutic compositions useful in such a method.
    Type: Application
    Filed: September 30, 2008
    Publication date: July 2, 2009
    Applicants: Juvaris Bio Therapeutics, Inc., Colorado State University Research Foundation
    Inventors: Steven W. Dow, Jeffery Fairman
  • Publication number: 20090171271
    Abstract: Disclosed is a surgical needle, or active cannula, that is capable of following a complex path through cavities and tissue within a patient's anatomy. The needle has a plurality of overlapping flexible tubes, each of which has a pre-formed curvature and a pre-determined flexibility. Each of the plurality of flexible tubes is selected based on their respective pre-formed curvature and flexibility so that a given overlap configuration causes the combination of overlapping flexible tubes to form a predetermined shape that substantially matches a desired path through the anatomy. By individually controlling the translation and angular orientation of each of the flexible tubes, the surgical needle may be guided through the anatomy according to the desired path.
    Type: Application
    Filed: November 15, 2006
    Publication date: July 2, 2009
    Applicant: The Johns Hopkins University
    Inventors: Robert James Webster, Allison M. Okamura, Noah J. Cowan, Russell H. Taylor
  • Publication number: 20090170102
    Abstract: In a first aspect, the present invention features methods for differentiating DNA species originating from different individuals in a biological sample. These methods may be used to differentiate or detect fetal DNA in a maternal sample or to differentiate DNA of an organ donor from DNA of an organ recipient. In preferred embodiments, the DNA species are differentiated by observing epigenetic differences in the DNA species such as differences in DNA methylation. In a second aspect, the present invention features methods of detecting genetic abnormalities in a fetus by detecting fetal DNA in a biological sample obtained from a mother. In a third aspect, the present invention features methods for differentiating DNA species originating from an organ donor from those of an organ recipient. In a fourth aspect, the present invention features kits for differentiating DNA species originating from different individuals in a biological sample.
    Type: Application
    Filed: October 13, 2008
    Publication date: July 2, 2009
    Applicant: The Chinese University of Hong Kong
    Inventors: Yuk Ming Dennis LO, Lit Man Poon
  • Patent number: 7554699
    Abstract: A method of watermark with hybrid halftone dots that is suitable for a printed shadow image. The watermark patterns that are composed of amplitude modulation (AM) and frequency modulation (FM) halftone dots (their concentration has been calibrated) cannot be perceived beyond a certain distance by the human eye. This is done through outputting the density calibration chart to choose the proper density parameters, which are applied to the manufacture process of the watermark with hybrid halftone dots. The hidden patterns of a watermark need to be pre-processed first, and thereby making the image blocks of AM and FM halftone dots to be combined smoothly. The copy machine, the lenticular lens and the optical scanner can detect the hidden watermark in the printed shadow image. Each secured document possesses a different serial number to achieve the document-version control.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: June 30, 2009
    Assignee: National Taipei Normal University
    Inventors: Hsi-Chun Wang, Pei-Chi Hsiao, Chi-Ming Lien