Abstract: A method for coating the tip of a mechanical resonator for use in magnetic force microscopy and magnetic resonance force microscopy in which the tip is coated with a ferromagnetic material and the cantilever is not, and the product resulting from the method. A cantilever and incorporated tip are coated with a photoresist, except that surface tension keeps photoresist off the tip. The cantilever and tip are then coated with a magnetic material. Next, acetone is used to lift off the magnetic material from the cantilever but not from the tip.

Abstract: Detectably-labeled compounds of formula (I) wherein A,B,C,D,E,F,R,X,Y and Z have any of the meanings given in the specification, and their pharmaceutically acceptable salts, are useful in competitive assays to assay for the presence of 2 receptors. Also disclosed are pharmaceutical compositions containing such a compound of formula (I), methods for their use and intermediates useful for preparing such compounds of formula (I).

Abstract: A method for isolating a mixture of anthocyanins, bioflavonoids and phenolics from an edible berry using adsorbent resins which are regenerable for reuse is described. The mixture with a consumable carrier is particularly useful in foods and as a dietary supplement or nutraceutical product.

Abstract: The present invention relates to a human cDNA homologous to the yeast REV1 gene. The sequence of human REV1 (hREV1) gene is described.

Abstract: A process for treating a textile substrate, the process including the steps of providing a textile substrate; providing a treatment bath; entraining a transport material in the treatment bath wherein the transport material further comprises a treatment material dissolved or suspended therein and wherein the transport material is substantially immiscible with the treatment bath; and contacting the textile substrate with the transport material in the treatment bath to thereby treat the textile substrate with the treatment material in the transport material.

Abstract: A ligand expressed by a general formula (1) in claim 1, wherein R1, R2 and R3 denote substituting groups on aromatic rings, X is P or As, and n is 1 to 3.

Abstract: An isolated DNA molecule is provided coding for a polypeptide of the 11-12 transmembrane domain transporter family having a Mg2+/H+ or Zn2+/H+ exchange activity, herein designated MHX. The genomic MHX DNA was isolated from Arabidopsis thaliana cv. C-24. Transgenic plants transformed with said DNA and expressing MHX are shown to have a lower content of sodium as compared with corresponding wild-type plants or a higher dry matter weight upon growth in calcium-rich media as compared with corresponding wild-type plants. These transgenic plants are tolerant to stress conditions, particularly high salinity and calcium-rich media, e.g. saline and calcareous soils.

Abstract: A computer implemented method cross-fades intensities of a plurality of overlapping images by identifying pixels in a target image that are only produced by a first source image. The weights of all the corresponding pixels in the first source image are set to one. Pixels in a second source images contributing to the target image are similarly identified and set to one. the weight of each remaining pixel in the first and second images is inversely proportional to a distance to a nearest pixel having a weight of one. Then, the first and second source image can be projected to form the target image.

Abstract: The present invention provides a method for view-angle tilt magnetic resonance imaging of an object having a localized variation of magnetic susceptibility. The method includes the steps of: applying an RF excitation pulse and a first field gradient simultaneously to the object; applying an RF refocusing pulse and a second field gradient simultaneously to the object; and applying a tilted readout gradient to the object, where the tilt angle is selected to provide incomplete removal of the image distortion produced by the magnetic susceptibility variation. In this manner, magnetic susceptibility contrast is provided in the region of variable magnetic susceptibility. Adjustment of the tilt angle can be used to provide a desired amount of magnetic susceptibility contrast.

Abstract: A new method to analyze and predict the binding energy for enzyme-transition state inhibitor interactions is presented. Computational neural networks are employed to discovery quantum mechanical features of transition states and putative inhibitors necessary for binding. The method is able to generate its own relationship between the quantum mechanical structure of the inhibitor and the strength of binding. Feed-forward neural networks with back propagation of error can be trained to recognize the quantum mechanical electrostatic potential at the entire van der Waals surface, rather than a collapsed representation, of a group of training inhibitors and to predict the strength of interactions between the enzyme and a group of novel inhibitors. The experimental results show that the neural networks can predict with quantitative accuracy the binding strength of new inhibitors.

Abstract: A seating apparatus for supporting a lower body region of an immobilized person for avoidance and relief of decubitus ulcers which provides regular intervals of seating pressure reduction below a predetermined seating pressure for a predetermined relief period. The seating apparatus includes a plurality of slats/cushions which may be displaced between a first support position wherein each of the slats/cushions is co-planar with a defined plane and a second displaced position wherein each of the slats/cushions is displaced a distance D from the defined plane for the predetermined relief period whereby capillary blood pressure is reduced below the predetermined seating pressure in the unsupported portion of the lower body region.

Abstract: The invention involves methods and products for oral gene therapy. Genes under the control of promoters are protectively contained in microparticles and delivered to cells in operative form, thereby obtaining noninvasive gene delivery for gene therapy.

Abstract: This invention relates to compositions and methods for the treatment of virus infections and other viral-associated disorders. Compositions comprise an inducing agent and an anti-viral agent. The inducing agent induces the expression of a cellular or viral product, such as viral thymidine kinase, increasing the sensitivity of proliferating cells to the anti-viral agent. Typical anti-viral agents are nucleoside analogs such as ganciclovir that inhibit viral replication. Methods involve administration of therapeutically effective amounts of the inducing agent with the anti-viral agent to destroy virus-infected cells. Viral infections that can be treated include infections by herpes viruses such as Kaposi's-associated herpes virus and Epstein-Barr virus, HIV infections and HTLV infections. These compositions and methods are particularly effective against episomal and latent infections in proliferating cells.

Abstract: A process for attaching a polyethylene glycol compound to a macromolecule to prepare a conjugate or adduct between the polyethylene glycol compound and the macromolecule is described. The process comprises the steps of (1) preparing an activated PEG or an activated PEG derivative by incorporating an acrylic ester, an acrylic thioester or an acrylamido group into the PEG or PEG derivative; (2) reacting the activated PEG or PEG derivative with a macromolecular material comprising one or more sulphydryl groups, primary amino groups and/or secondary amino groups and (3) recovering the conjugate of the PEG or PEG derivative and the macromolecular material.

Abstract: A method of fabricating a fully dense, three dimensional object by direct laser sintering is disclosed. In a chamber with a partial pressure atmosphere, a beam of directed energy melts metallic powder in order to form a solid layer cross section. Another layer of powder is deposited and melted, along with a portion of the previous layer. The energy beam typically is in the form of a laser, scanning along a path resembling a parametric curve or another, arbitrary piecewise parametric curve. In another embodiment, the previous layer is not remelted, thus creating an oxide film that acts as a clean stop to prevent unwanted downward growth.

Abstract: A gas-enriched fluid is provided by the combination of a first fluid, such as a patient's blood, with a second gas-supersaturated fluid, such as an oxygen supersaturated fluid. In this example, a catheter assembly includes a portion that receives the patient's blood from a pump and that receives the oxygen supersaturated fluid from an appropriate fluid source. The oxygen supersaturated fluid is advantageously combined with the blood in an area of laminar flow, and then this gas-enriched fluid is delivered to the patient through an appropriate lumen coupled to the portion of the catheter assembly.

Abstract: The subject invention provides plants with excellent resistance to powdery mildew. In a specific embodiment, the subject invention provides dogwood (Cornus florida) cultivars that are resistant to infestation with powdery mildew. Specifically exemplified herein are culitvars identified as ‘Jean's Appalachian Snow’, ‘Kay's Appalachian Mist’, and ‘Karen's Appalachian Blush’. The present invention also provides materials and methods for identifying, characterizing, and/or producing powdery mildew resistant plants. In a specific embodiment, the subject invention provides polynucleotide sequences, and patterns of polynucleotide sequences, which are associated with resistance to powdery mildew. These polynucleotides are characteristic of the powdery mildew resistant plants as described herein. Such polynucleotides are particularly useful in identifying and characterizing plant having resistance to powdery mildew.

Abstract: Modified starch materials having a number average molecular weight of at least 10,000 for nutritional products provide a relatively slow release of metabolizable carbohydrates, giving a source of carbohydrate energy over a longer period of time than can be obtained from glucose and other carbohydrates such as lactose, fructose, or sucrose. Such modified starch material possess altered processing and pasting profile characteristics.

Abstract: A self-similar log-periodic antenna is described comprising a plurality of substantially triangular conductive elements, 4, symmetrically disposed in either planar or curved configurations about a central conductive boom to form an antenna arm. Two or more antenna arms are assembled into an antenna by symmetrically locating such antenna arms substantially in the shape of a pyramid (for planar arms) or in a conical shape (for curved arms). Some embodiments include a conductive fin, 5, to reduce cross-polarization coupling between antenna arms. Some embodiments include a grounded conductive shield on the interior of the antenna providing electromagnetic shielding for the interior region of the antenna while preserving the self-similar geometry of the antenna and shield combination.

Abstract: A structure and method for providing a broken symmetry reflector structure for a solar concentrator device. The component of the optical direction vector along the symmetry axis is conserved for all rays propagated through a translationally symmetric optical device. This quantity, referred to as the translational skew invariant, is conserved in rotationally symmetric optical systems. Performance limits for translationally symmetric nonimaging optical devices are derived from the distributions of the translational skew invariant for the optical source and for the target to which flux is to be transferred. A numerically optimized non-tracking solar concentrator utilizing symmetry-breaking reflector structures can overcome the performance limits associated with translational symmetry.